Leila Mohammadi, MD, PhD
Assistant Researcher
Medicine
School of Medicine

Dr. Mohammadi is a physician-scientist and an Early Career Investigator with over 12 years of experience in clinical vascular studies including pre-doctoral work with much of it focused on studying vascular effects of tobacco and marijuana exposure. She has clinical and research background in cardiac arrhythmias, hypertension, and endothelial dysfunction. Dr. Mohammadi is leading the UCSF CANDIDE study, which investigates the effects of chronic cannabis use on vascular function.

Awards

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• Leila Mohammadi, American Heart Association Early Career Travel Award, 2023
• Leila Mohammadi, American Heart Association Postdoctoral Fellowship, 2019-2021

Education & Training

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• Postdoctoral Cardiovascular Diseases Research University of California, San Francisco 04/2021
• PhD Cardiovascular Diseases Research I.M. Sechenov First Moscow State Medical University 11/2014
• Fellowship General Cardiology I.M. Sechenov First Moscow State Medical Univesity 11/2014
• Residency Internal Medicine I.M. Sechenov First Moscow State Medical Univesity I.M. Sechenov 08/2011
• MD General Medicine Moscow Medical Academy I.M. Sechenov 06/2009

Interests

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• Cardiovascular disease
• endothelial function
• Tobacco control
• e-cigarettes
• cannabis use

Websites

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• CANDIDE Study (candide.ucsf.edu)

Grants and Projects

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• Effects of chronic marijuana use on endothelial function, NIH/NIDA, 2023-2028
• Double Trouble: the effects of dual cannabis and tobacco use on vascular function, California Tobacco-Related Disease Research Program Early Career Investigator Award, 2024-2027
• Effects of chronic cannabis use on endothelial function, California Department of Cannabis Control, 2021-2023
• Relative Endothelial Toxicity of Tobacco Smoke and E-Cigarette Aerosol: A Functional and Mechanistic Assessment., UCSF Research Allocation Program, 2020-2021

Publications (20)

Top publication keywords:
Anti-Arrhythmia AgentsEndothelium, VascularEndothelial CellsHypertensionAerosolsReceptor for Advanced Glycation End ProductsNitric Oxide SynthaseHMGB1 ProteinCigarette SmokingVascular Endothelial Growth Factor AElectronic Nicotine Delivery SystemsHydrogen PeroxideVapingTobacco ProductsAtrial Fibrillation

• Chronic E-Cigarette Use Impairs Endothelial Function on the Physiological and Cellular Levels.
  Arteriosclerosis, thrombosis, and vascular biology 2022 Mohammadi L, Han DD, Xu F, Huang A, Derakhshandeh R, Rao P, Whitlatch A, Cheng J, Keith RJ, Hamburg NM, Ganz P, Hellman J, Schick SF, Springer ML
• Impairment of Endothelial Function by Cigarette Smoke and e-Cigarette Aerosol Requires RAGE.
  Arteriosclerosis, thrombosis, and vascular biology 2023 Han DD, Rao P, Qiu H, Navabzadeh M, Wang X, Goyal N, Mohammadi L, Huang A, Perez BG, Schick SF, Springer ML
• Increased vulnerability to atrial and ventricular arrhythmias caused by different types of inhaled tobacco or marijuana products.
  Heart rhythm 2022 Qiu H, Zhang H, Han DD, Derakhshandeh R, Wang X, Goyal N, Navabzadeh M, Rao P, Wilson EE, Mohammadi L, Olgin JE, Springer ML
• Comparable Impairment of Vascular Endothelial Function by a Wide Range of Electronic Nicotine Delivery Devices.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2022 Rao P, Han DD, Tan K, Mohammadi L, Derakhshandeh R, Navabzadeh M, Goyal N, Springer ML
• Functional Impairment of Endothelial Cells in vitro After Exposure to Serum From E-cigarette Users
  Functional Impairment of Endothelial Cells in vitro After Exposure to Serum From E-cigarette Users 2020 Leila Mohammadi , Daniel Han , Ronak Derakhshandeh , Abel Huang , Adam Whitlatch , Fengyun Xu , Rachel J Keith , Naomi Hamburg , Peter Ganz , Judith Hellman , Suzaynn F Schick , Matthew L Springer

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• Circulation
  The Effects of Tobacco Smoking and Electronic Cigarette Use on the Level of Albuminuria and Vascular Augmentation Index in Young Healthy Population 2019 Anna Bragina, Natalia Druzhinina, Leila Mohammadi, Evgenii Khvalin, Artem Dubchak, Luba Vasilyeva, Valery Podzolkov
• Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells.
  Journal of the American College of Cardiology 2019 Lee WH, Ong SG, Zhou Y, Tian L, Bae HR, Baker N, Whitlatch A, Mohammadi L, Guo H, Nadeau KC, Springer ML, Schick SF, Bhatnagar A, Wu JC
• Relative endothelial toxicity of tobacco smoke and e-cigarette aerosol: A functional and mechanistic assessment
  Relative endothelial toxicity of tobacco smoke and e-cigarette aerosol: A functional and mechanistic assessment. 2018 Leila Mohammadi, Ronak Derakhshande, Daniel D Han, Abel Huang, Adam Witlatch, Suzaynn F schick, Matthew L Springer
• Predictors of progression of atrial fibrillation in patients with congestive heart failure
  Predictors of progression of atrial fibrillation in patients with congestive heart failure 2017 Podzolkov V.I., Tarzimanova A.I., Mohammadi L.
• [Progression of Atrial Fibrillation in Patients With Arterial Hypertension When Choosing Different Treatment Strategies for Arrhythmia].
  Kardiologiia 2017 Podzolkov VI, Tarsimanova AI, Mohammadi LN
• Statins in secondary prevention of atrial fibrillation in hypertensive patients
  Statins in secondary prevention of atrial fibrillation in hypertensive patients 2017 Podzolkov, V.; Tarzimanova, A.; Pisarev, M.; Gataulin, R.; Mohammadi, L.
• Changes of vascular wall rigidity and endothelial function in hypertensive patients with atrial fibrillation
  Changes of vascular wall rigidity and endothelial function in hypertensive patients with atrial fibrillation 2014 Leila Mohammadi (Thesis in Russian)
• Change in vascular wall rigidity in hypertensive patients with persistence atrial fibrillation
  2014 A. Tarzimanova, Candidate of Medical Sciences; Professor V. Podzolkov, MD; L. Mokhammadi; I. Loria I.M.
• [The altered endothelial function in patients with arterial hypertension and different forms of atrial fibrillation].
  Klinicheskaia meditsina 2014 Podzolkov VI, Tarzimanova AI, Mokhammadi LN
• Does treatment strategy for atrial fibrillation influence myocardial contractile function?
  2013 Valery Podzolkov, Aida Tarzimanova , Irakli Loriya, Leila Mohammadi
• Correlation of vascular wall stiffness with the left atrial size in hypertensive patients with atrial fibrillation
  Correlation of vascular wall stiffness with the left atrial size in hypertensive patients with atrial fibrillation 2013 Mohammadi LN, Podzolkov VI, Tarzimanova AI, Pisarev MV
• Changes of collagen III binding activity of von Willebrand factor in hypertensive patients with different forms of atrial fibrillation
  Changes of collagen III binding activity of von Willebrand factor in hypertensive patients with different forms of atrial fibrillation 2013 Mohammadi L, Tarzimanova A, Podzolkov V, Pisarev M, Loriya I
• Effects of Propafenone on Myocardial Inotropic Function in Patients with Hypertension and Atrial Fibrillation
  Effects of Propafenone on Myocardial Inotropic Function in Patients with Hypertension and Atrial Fibrillation 2012 Tarzimanova A.I., Podzolkov V.I., Loriya I. Zh., Mokhammadi L.N.
• Comparing the changes in cardiac rhythm turbulence in 2 groups of patients diagnosed with IHD group 1 suffer from Atrial Fibrillation, Group 2 not suffer from Atrial Fibrillation
  Comparing the changes in cardiac rhythm turbulence in 2 groups of patients diagnosed with IHD group 1 suffer from Atrial Fibrillation, Group 2 not suffer from Atrial Fibrillation 2010 Mohammadi L, Podzolkov VI, Matveev VV, Abramova AA
• Cardiac Rhabdomyoma in fetus with Tuberous sclerosis
  Cardiac Rhabdomyoma in fetus with Tuberous sclerosis 2009 Mohammadi L, Kogan E