Lee Schnaider, PhD
Postdoctoral Scholar
Pharmaceutical Chemistry
School of Pharmacy

Publications (19)

Top publication keywords:
Anti-Infective AgentsMetal NanoparticlesSilkStaphylococcus epidermidisBiocompatible MaterialsCandida albicansBacterial AdhesionMolecular Dynamics SimulationSilverNanotechnologyHydrogelsDipeptidesNanostructuresHistatinsNanofibers

• De novo design of semisynthetic conduction pores.
  Nature structural & molecular biology 2026 Schnaider L, Hatstat AK, Scott AJ, Tan SK, Hambley RG, Dawson WM, Griffiths RC, Kormos RC, Melo AA, Tse E, Polizzi NF, Wallace EJ, Merz GE, DeGrado WF
• BoltzGen: Toward Universal Binder Design.
  bioRxiv : the preprint server for biology 2025 Stark H, Faltings F, Choi M, Xie Y, Hur E, O'Donnell T, Bushuiev A, Uçar T, Passaro S, Mao W, Reveiz M, Bushuiev R, Pluskal T, Sivic J, Kreis K, Vahdat A, Ray S, Goldstein JT, Savinov A, Hambalek JA, …
• De novo design of semisynthetic protein nanopores.
  bioRxiv : the preprint server for biology 2025 Schnaider L, Hatstat AK, Scott AJ, Tan SK, Hambley RG, Dawson WM, Griffiths RC, Kormos RC, Melo AA, Tse E, Polizzi NF, Wallace EJ, Merz GE, DeGrado WF
• SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex.
  Journal of the American Chemical Society 2024 Schnaider L, Tan S, Singh PR, Capuano F, Scott AJ, Hambley R, Lu L, Yang H, Wallace EJ, Jo H, DeGrado WF
• Ultrashort Cell-Penetrating Peptides for Enhanced Sonophoresis-Mediated Transdermal Transport.
  ACS applied bio materials 2020 Schnaider L, Shimonov L, Kreiser T, Zaguri D, Bychenko D, Brickner I, Kolusheva S, Lichtenstein A, Kost J, Gazit E

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• Biomimetic peptide self-assembly for functional materials.
  Nature reviews. Chemistry 2020 Levin A, Hakala TA, Schnaider L, Bernardes GJL, Gazit E, Knowles TPJ
• Peptide Self-Assembly Is Linked to Antibacterial, but Not Antifungal, Activity of Histatin 5 Derivatives.
  mSphere 2020 Schnaider L, Rosenberg A, Kreiser T, Kolusheva S, Gazit E, Berman J
• Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo.
  Nano letters 2020 Schnaider L, Toprakcioglu Z, Ezra A, Liu X, Bychenko D, Levin A, Gazit E, Knowles TPJ
• High-Efficiency Fluorescence through Bioinspired Supramolecular Self-Assembly.
  ACS nano 2020 Chen Y, Orr AA, Tao K, Wang Z, Ruggiero A, Shimon LJW, Schnaider L, Goodall A, Rencus-Lazar S, Gilead S, Slutsky I, Tamamis P, Tan Z, Gazit E
• Reevaluating the Microbial Infection Link to Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD 2020 Schnaider L, Arnon ZA, Gazit E
• Composite of Peptide-Supramolecular Polymer and Covalent Polymer Comprises a New Multifunctional, Bio-Inspired Soft Material.
  Macromolecular rapid communications 2019 Chakraborty P, Ghosh M, Schnaider L, Adadi N, Ji W, Bychenko D, Dvir T, Adler-Abramovich L, Gazit E
• Unravelling the role of amino acid sequence order in the assembly and function of the amyloid-β core.
  Chemical communications (Cambridge, England) 2019 Bera S, Arad E, Schnaider L, Shaham-Niv S, Castelletto V, Peretz Y, Zaguri D, Jelinek R, Gazit E, Hamley IW
• Enhanced Nanoassembly-Incorporated Antibacterial Composite Materials.
  ACS applied materials & interfaces 2019 Schnaider L, Ghosh M, Bychenko D, Grigoriants I, Ya'ari S, Shalev Antsel T, Matalon S, Sarig R, Brosh T, Pilo R, Gazit E, Adler-Abramovich L
• Expanding the Functional Scope of the Fmoc-Diphenylalanine Hydrogelator by Introducing a Rigidifying and Chemically Active Urea Backbone Modification.
  Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Basavalingappa V, Guterman T, Tang Y, Nir S, Lei J, Chakraborty P, Schnaider L, Reches M, Wei G, Gazit E
• Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity.
  Nature communications 2017 Schnaider L, Brahmachari S, Schmidt NW, Mensa B, Shaham-Niv S, Bychenko D, Adler-Abramovich L, Shimon LJW, Kolusheva S, DeGrado WF, Gazit E
• Extension of the generic amyloid hypothesis to nonproteinaceous metabolite assemblies.
  Science advances 2015 Shaham-Niv S, Adler-Abramovich L, Schnaider L, Gazit E
• Computational and experimental characterization of dVHL establish a Drosophila model of VHL syndrome.
  PloS one 2014 Shmueli MD, Schnaider L, Herzog G, Gazit E, Segal D
• The influence of chemical chaperones on enzymatic activity under thermal and chemical stresses: common features and variation among diverse chemical families.
  PloS one 2014 Levy-Sakin M, Berger O, Feibish N, Sharon N, Schnaider L, Shmul G, Amir Y, Buzhansky L, Gazit E
• Structural insights into the folding defects of oncogenic pVHL lead to correction of its function in vitro.
  PloS one 2013 Shmueli MD, Schnaider L, Rosenblum D, Herzog G, Gazit E, Segal D