Laura Esserman, MD
Professor
Surgery
School of Medicine
laura.esserman@ucsf.edu 415-885-7691
Dr. Laura Esserman, M.D., M.B.A is a surgeon and breast cancer oncology specialist practicing at the UCSF Breast Care Center where she has also held the position of Director since 1996. She co-leads the Breast Oncology Program, the largest of the UCSF Helen Diller Comprehensive Cancer Center's multidisciplinary programs.
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The program is comprised of 69 faculty members who represent 16 academic specialties and is internationally recognized and well-established with major initiatives in epidemiology, genetics, biology, therapeutics, and clinical cancer care. She is a professor of Surgery & Radiology at UCSF and faculty at the UCSF Helen Diller Family Comprehensive Cancer Center where she founded the program in Translational Informatics. As part of this program, her research has focused on bioinformatics, medical and clinical informatics, systems integration, and clinical care delivery.
She has worked at UCSF to develop interdisciplinary teams of clinicians and researchers to bring the best care to patients and find the best platform to integrate translational research and improve the delivery of breast cancer care. In 2005, she received the NCI SPORE Investigator of the Year Award, an internationally recognized honor and designation.
She is the Principal Investigator of the I-SPY TRIAL program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design.
Dr. Esserman launched a University of California-wide breast cancer initiative called the Athena Breast Health Network, a project designed to follow 400,000 women from screening through treatment and outcomes, incorporating the latest in molecular testing and web-based tools into the course of care.
Dr. Esserman is nationally and internationally known as a leader in the field of breast cancer and has published over 200 articles in peer-reviewed journals covering all aspects of breast health including information systems, immunology, decision making, health policy and the use of imaging. She speaks extensively at public and private forums within the U.S. and internationally. Overall, Dr. Esserman's research and writing tends to focus on the goal of giving patients better access to accurate information so that they can become partners in their health care.
She was a member of President Obama’s Council of Advisors on Science and Technology (PCAST) Working Group on Advancing Innovation in Drug Development and Evaluation, which studied how the federal government can best support science-based innovation in the process of drug development and regulatory evaluation. In addition, she was a contributing member of a “taskforce” for President Obama’s Council of Advisors on Science and Technology.
Dr. Esserman received her Bachelor's degree in History of Science from Harvard University and completed her M.D. at Stanford University. She completed her surgery residency and oncology fellowship at Stanford University Medical Center. After her training, she joined the faculty at Stanford and received a Hartford fellowship to attend Stanford Business School where she received her M.B.A. in 1993. She then joined the faculty at the University of California, San Francisco.
Websites
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- UCSF General Surgery (general.surgery.ucsf.edu)
- Profile at UCSF Cancer Center (cancer.ucsf.edu)
Grants and Projects
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- Surgical Oncology Training Grant, NIH, 2020-2025
- Extending the Diversity, Reach, and Generalizability of the WISDOM Study, NIH, 2020-2025
- I-SPY2 +: Evolving the I-SPY 2 TRIAL to include MRI-directed, adaptive sequential treatment to optimize breast cancer outcomes, NIH, 2017-2022
- Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancers, NIH, 2015-2021
- Modeling the Impact of Targeted Therapy Based on Breast Cancer Subtypes, NIH, 2014-2020
- Integrated Biomarkers to Characterize Breast Cancer Risk, NIH, 2004-2011
Publications (462)
Top publication keywords:
MammographyMammaplastyCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularNeoadjuvant TherapyCarcinoma, Ductal, BreastNeoplasm Recurrence, LocalOrgan Sparing TreatmentsMastectomyReceptors, EstrogenEarly Detection of CancerMastectomy, SegmentalReceptor, ErbB-2NipplesBreast Neoplasms
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Correction: A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.
Breast cancer research and treatment 2024 Leggat-Barr K, Yee D, Duralde E, Hodge C, Borges V, Baxter M, Valdez J, Morgan T, Garber J, Esserman L -
Bilateral Mastectomy vs Lumpectomy and Breast Cancer Mortality Risk.
JAMA oncology 2024 O'Keefe TJ, Alvarado MD, Esserman LJ -
Differential long-term tamoxifen therapy benefit by menopausal status in breast cancer patients: secondary analysis of a controlled randomized clinical trial.
Journal of the National Cancer Institute 2024 Johansson A, Dar H, Nordenskjöld A, Perez-Tenorio G, Tobin NP, Yau C, Benz CC, Esserman LJ, van 't Veer LJ, Nordenskjöld B, Stål O, Fornander T, Lindström LS -
Impact of IVF Restriction on Patients With Cancer and Surgeons.
JAMA surgery 2024 Glencer AC, Esserman LJ -
Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.
Breast cancer research and treatment 2024 Rugo HS, Campbell M, Yau C, Jo Chien A, Wallace AM, Isaacs C, Boughey JC, Han HS, Buxton M, Clennell JL, Asare SM, Steeg K, Wilson A, Singhrao R, Matthews JB, Perlmutter J, Fraser Symmans W, Hylton NM…
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Relationship Between Perceived COVID-19 Risk and Change in Perceived Breast Cancer Risk: Prospective Observational Study.
JMIR cancer 2024 Baxter-King R, Naeim A, Huang TQ, Sepucha K, Stanton A, Rudkin A, Ryu R, Sabacan L, Vavreck L, Esserman L, Stover Fiscalini A, Wenger NS -
Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospective Study.
Tomography (Ann Arbor, Mich.) 2024 Li W, Le NN, Nadkarni R, Onishi N, Wilmes LJ, Gibbs JE, Price ER, Joe BN, Mukhtar RA, Gennatas ED, Kornak J, Magbanua MJM, Van't Veer LJ, LeStage B, Esserman LJ, Hylton NM -
Hormone Receptor Positive HER2-negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple Negative Breast Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Rios-Hoyo A, Xiong K, Dai J, Yau C, Marczyk M, Garcia-Milian R, Wolf DM, Huppert LA, Nanda R, Hirst GL, Cobain EF, van 't Veer LJ, Esserman LJ, Pusztai L -
A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.
Breast cancer research and treatment 2024 Leggat-Barr K, Yee D, Duralde E, Hodge C, Borges V, Baxter M, Valdez J, Morgan T, Garber J, Esserman L -
Balancing risks of surgical complications and positive margins for patients with invasive lobular carcinoma of the breast and elevated BMI: An institutional cohort study.
American journal of surgery 2024 Falade I, Switalla K, Quirarte A, Baxter M, Soroudi D, Rothschild H, Abe SE, Goodwin K, Piper M, Alvarado M, Julian BQ, Ewing C, Wong J, Rose J, Esserman L, Foster R, Mukhtar RA -
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
Cell reports. Medicine 2024 Campbell MJ, Wolf DM, Yau C, Brown-Swigart L, Wulfkuhle J, Gallagher IR, Zhu Z, Bolen J, Vandenberg S, Hoyt C, Mori H, Borowsky A, Sit L, Perlmutter J, Asare SM, I-SPY2 Investigators, Nanda R, Liu MC,… -
Screening Mammography for 40-Year-Old Women-Whose Decision?
JAMA internal medicine 2024 Kerlikowske K, Esserman L, Tice JA -
Gut and oral microbial compositional differences in women with breast cancer, women with ductal carcinoma in situ, and healthy women.
mSystems 2024 McCune E, Sharma A, Johnson B, O'Meara T, Theiner S, Campos M, Heditsian D, Brain S, Gilbert JA, Esserman L, Campbell MJ -
Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.
Annals of oncology : official journal of the European Society for Medical Oncology 2024 Huppert LA, Wolf D, Yau C, Brown-Swigart L, Hirst GL, Isaacs C, Pusztai L, Pohlmann PR, DeMichele A, Shatsky R, Yee D, Thomas A, Nanda R, Perlmutter J, Heditsian D, Hylton N, Symmans F, Veer LJV', … -
Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM study.
NPJ breast cancer 2024 Wang T, Che M, Huilgol YS, Keane H, Goodman D, Soonavala R, Ozanne E, Shieh Y, Belkora JK, Fiscalini AS, Athena Breast Health Network Investigators and Advocate Partners, Esserman LJ -
Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy.
Breast cancer research and treatment 2024 Jacob S, Christofferson A, Fisch S, Norwood P, Castillo P, Yu H, Hirst G, Soliman H, Nanda R, Mukhtar RA, Ewing C, Majure M, Melisko M, Rugo HS, Esserman L, Price E, Chien AJ -
Overcoming challenges in conducting early phase breast cancer prevention trials: Bazedoxifene and conjugated estrogens vs waitlist control.
Contemporary clinical trials 2024 Fabian CJ, Mudaranthakam DP, Gajewski B, Young K, Winblad O, Khan SA, Garber JE, Esserman LJ, Yee LD, Nye L, Powers KR, Ranallo L, Kreutzjans AL, Pittman K, Altman C, Metheny T, Zelenchuk A, Komm BS, … -
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.
Nature medicine 2024 Khoury K, Meisel JL, Yau C, Rugo HS, Nanda R, Davidian M, Tsiatis B, Chien AJ, Wallace AM, Arora M, Rozenblit M, Hershman DL, Zimmer A, Clark AS, Beckwith H, Elias AD, Stringer-Reasor E, Boughey JC, … -
Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.
Nature medicine 2024 Shatsky RA, Trivedi MS, Yau C, Nanda R, Rugo HS, Davidian M, Tsiatis B, Wallace AM, Chien AJ, Stringer-Reasor E, Boughey JC, Omene C, Rozenblit M, Kalinsky K, Elias AD, Vaklavas C, Beckwith H, … -
Implementation and impact of an electronic patient reported outcomes system in a phase II multi-site adaptive platform clinical trial for early-stage breast cancer.
Journal of the American Medical Informatics Association : JAMIA 2024 Northrop A, Christofferson A, Umashankar S, Melisko M, Castillo P, Brown T, Heditsian D, Brain S, Simmons C, Hieken T, Ruddy KJ, Mainor C, Afghahi A, Tevis S, Blaes A, Kang I, Asare A, Esserman L, … -
Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence.
JAMA 2024 Franklin JB, Marra C, Abebe KZ, Butte AJ, Cook DJ, Esserman L, Fleisher LA, Grossman CI, Kass NE, Krumholz HM, Rowan K, Abernethy AP, JAMA Summit on Clinical Trials Participants -
Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.
NPJ breast cancer 2024 Greenwood HI, Maldonado Rodas CK, Freimanis RI, Glencer AC, Miller PN, Mukhtar RA, Brabham C, Yau C, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky A, Hylton N, Esserman LJ, Basu A -
Clipping the Positive Lymph Node in Patients with Clinically Node Positive Breast Cancer Treated with Neoadjuvant Chemotherapy: Impact on Axillary Surgery in the ISPY-2 Clinical Trial.
Annals of surgical oncology 2024 Switalla KM, Boughey JC, Dimitroff K, Yau C, Ladores V, Yu H, Tchou J, Golshan M, Ahrendt G, Postlewait LM, Piltin M, Reyna CR, Matsen CB, Tuttle TM, Wallace AM, Arciero CA, Lee MC, Tseng J, Son J, … -
Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial.
Annals of surgical oncology 2024 Piltin MA, Norwood P, Ladores V, Mukhtar RA, Sauder CA, Golshan M, Tchou J, Rao R, Lee MC, Son J, Reyna C, Hewitt K, Kuerer H, Ahrendt G, Greenwalt I, Tseng J, Postlewait L, Howard-McNatt M, Jaskowiak… -
Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Magbanua MJM, Ahmed Z, Sayaman RW, Brown Swigart L, Hirst GL, Yau C, Wolf DM, Li W, Delson AL, Perlmutter J, Pohlmann P, Symmans WF, Yee D, Hylton NM, Esserman LJ, DeMichele AM, Rugo HS, van 't Veer … -
Tumor microenvironmental determinants of high-risk DCIS progression.
Research square 2024 Borowsky A, Glencer A, Ramalingam K, Schindler N, Mori H, Ghule P, Lee K, Nachmanson D, Officer A, Harismendy O, Stein J, Stein G, Evans M, Weaver D, Yau C, Hirst G, Campbell M, Esserman L -
Reproductive rights in the United States: acquiescence is not a strategy.
Nature medicine 2024 Esserman LJ, Yee D -
Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.
Cancer research communications 2024 Wescott EC, Sun X, Gonzalez-Ericsson P, Hanna A, Taylor BC, Sanchez V, Bronzini J, Opalenik SR, Sanders ME, Wulfkuhle J, Gallagher RI, Gomez H, Isaacs C, Bharti V, Wilson JT, Ballinger TJ, Santa-Maria… -
Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor-Positive Human Epidermal Growth Factor 2-Negative Breast Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2024 Ríos-Hoyo A, Cobain E, Huppert LA, Beitsch PD, Buchholz TA, Esserman L, van 't Veer LJ, Rugo HS, Pusztai L -
RE: Supplemental magnetic resonance imaging plus mammography compared with magnetic resonance imaging or mammography by extent of breast density.
Journal of the National Cancer Institute 2024 Omoleye OJ, Esserman LJ, Olopade OI -
Incidence and Mitigation of Corneal Pseudomicrocysts Induced by Antibody-Drug Conjugates (ADCs).
Current ophthalmology reports 2024 Lindgren ES, Yan R, Cil O, Verkman AS, Chan MF, Seitzman GD, Farooq AV, Huppert LA, Rugo HS, Pohlmann PR, Lu J, Esserman LJ, Pasricha ND -
Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.
bioRxiv : the preprint server for biology 2024 Wang J, Suh JM, Woo BJ, Navickas A, Garcia K, Yin K, Fish L, Cavazos T, Hänisch B, Markett D, Yu S, Hirst G, Brown-Swigart L, Esserman LJ, van 't Veer LJ, Goodarzi H -
18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.
Radiology. Imaging cancer 2024 Diwanji D, Onishi N, Hathi DK, Lawhn-Heath C, Kornak J, Li W, Guo R, Molina-Vega J, Seo Y, Flavell RR, Heditsian D, Brain S, Esserman LJ, Joe BN, Hylton NM, Jones EF, Ray KM -
Circulating tumor cells in early lobular versus ductal breast cancer and their associations with prognosis.
NPJ breast cancer 2024 Alkhafaji S, Wolf DM, Magbanua MJM, J van 't Veer L, Park JW, Esserman L, Mukhtar RA -
Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.
Critical care (London, England) 2024 Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS, I-SPY COVID Consortium -
Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery.
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Albain KS, Yau C, Petricoin EF, Wolf DM, Lang JE, Chien AJ, Haddad T, Forero-Torres A, Wallace AM, Kaplan H, Pusztai L, Euhus D, Nanda R, Elias AD, Clark AS, Godellas C, Boughey JC, Isaacs C, Tripathy… -
Duration of Endocrine Treatment for DCIS impacts second events: Insights from a large cohort of cases at two academic medical centers.
Research square 2024 O'Keefe T, Yau C, Iaconetti E, Jeong E, Brabham C, Kim P, McGuire J, Griffin A, Wallace A, Esserman L, Harismendy O, Hirst G -
Characterizing attitudes related to future child-bearing in young women diagnosed with early-stage breast cancer.
Breast cancer research and treatment 2024 Umashankar S, Li M, Blevins K, Kim MO, Majure M, Park J, Huppert LA, Melisko M, Rugo HS, Esserman L, Chien AJ -
Precision Oncology in Breast Cancer Surgery.
Surgical oncology clinics of North America 2024 Abbasi AB, Wu V, Lang JE, Esserman LJ -
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.
Cell reports. Medicine 2023 Gallagher RI, Wulfkuhle J, Wolf DM, Brown-Swigart L, Yau C, O'Grady N, Basu A, Lu R, Campbell MJ, Magbanua MJ, Coppé JP, I-SPY 2 Investigators, Asare SM, Sit L, Matthews JB, Perlmutter J, Hylton N, … -
Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.
JAMA network open 2023 Kyalwazi B, Yau C, Campbell MJ, Yoshimatsu TF, Chien AJ, Wallace AM, Forero-Torres A, Pusztai L, Ellis ED, Albain KS, Blaes AH, Haley BB, Boughey JC, Elias AD, Clark AS, Isaacs CJ, Nanda R, Han HS, … -
Concordance between patient-reported and physician-documented comorbidities and symptoms among Stage 4 breast cancer patients.
Cancer medicine 2023 Umashankar S, Basu A, Esserman L, Van't Veer L, Melisko ME -
The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB).
Breast cancer research and treatment 2023 Rothschild HT, Clelland EN, Abel MK, Chien AJ, Shui AM, Esserman L, Khan SA, Mukhtar RA -
Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification.
Nature reviews. Endocrinology 2023 Ho KKY, Kaiser UB, Chanson P, Gadelha M, Wass J, Nieman L, Little A, Aghi MK, Raetzman L, Post K, Raverot G, Borowsky AD, Erickson D, Castaño JP, Laws ER, Zatelli MC, Sisco J, Esserman L, Yuen KCJ, … -
Area Deprivation Index in Patients with Invasive Lobular Carcinoma of the Breast: Associations with Tumor Characteristics and Outcomes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2023 Kaur M, Patterson A, Molina-Vega J, Rothschild H, Clelland E, Ewing CA, Mujir F, Esserman LJ, Olopade OI, Mukhtar RA -
Early Ascertainment of Breast Cancer Diagnoses Comparing Self-Reported Questionnaires and Electronic Health Record Data Warehouse: The WISDOM Study.
JCO clinical cancer informatics 2023 Leggat-Barr K, Ryu R, Hogarth M, Stover-Fiscalini A, Veer LV', Park HL, Lewis T, Thompson C, Borowsky A, Hiatt RA, LaCroix A, Parker B, Madlensky L, Naeim A, Esserman L -
The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database.
Research square 2023 Rothschild HT, Clelland EN, Abel MK, Chien AJ, Shui AM, Esserman L, Khan SA, Mukhtar RA -
Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy.
Annals of surgical oncology 2023 Rothschild HT, Clelland EN, Mujir F, Record H, Wong J, Esserman LJ, Alvarado M, Ewing C, Mukhtar RA -
Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment.
Radiology. Imaging cancer 2023 Onishi N, Bareng TJ, Gibbs J, Li W, Price ER, Joe BN, Kornak J, Esserman LJ, Newitt DC, Hylton NM, I-SPY 2 Imaging Working Group, I-SPY 2 Investigator Network -
A Truly Pro-Life Position Requires Access to Reproductive Health Care.
Journal of women's health (2002) 2023 Hull SC, Chou JC, Yee LM, Yee D, Esserman L -
Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial.
Annals of surgical oncology 2023 Boughey JC, Yu H, Dugan CL, Piltin MA, Postlewait L, Son JD, Edmiston KK, Godellas CV, Lee MC, Carr MJ, Tonneson JE, Crown A, Lancaster RB, Woriax HE, Ewing CA, Chau HS, Patterson AK, Wong JM, … -
Breast Conservation Surgery and Mastectomy Have Similar Locoregional Recurrence After Neoadjuvant Chemotherapy: Results From 1462 Patients on the Prospective, Randomized I-SPY2 Trial.
Annals of surgery 2023 Mukhtar RA, Chau H, Woriax H, Piltin M, Ahrendt G, Tchou J, Yu H, Ding Q, Dugan CL, Sheade J, Crown A, Carr M, Wong J, Son J, Yang R, Chan T, Terando A, Alvarado M, Ewing C, Tonneson J, Tamirisa N, … -
Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.
Frontiers in oncology 2023 Yu K, Basu A, Yau C, Wolf DM, Goodarzi H, Bandyopadhyay S, Korkola JE, Hirst GL, Asare S, DeMichele A, Hylton N, Yee D, Esserman L, van 't Veer L, Sirota M -
Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study.
Radiology 2023 Arasu VA, Habel LA, Achacoso NS, Buist DSM, Cord JB, Esserman LJ, Hylton NM, Glymour MM, Kornak J, Kushi LH, Lewis DA, Liu VX, Lydon CM, Miglioretti DL, Navarro DA, Pu A, Shen L, Sieh W, Yoon HC, Lee … -
Prognostic Significance of Residual Ductal Carcinoma In Situ After Complete Response of Invasive Breast Cancer to Neoadjuvant Therapy-Reply.
JAMA surgery 2023 Mukhtar RA, Yau C, Esserman LJ -
Development and testing of a polygenic risk score for breast cancer aggressiveness.
NPJ precision oncology 2023 Shieh Y, Roger J, Yau C, Wolf DM, Hirst GL, Swigart LB, Huntsman S, Hu D, Nierenberg JL, Middha P, Heise RS, Shi Y, Kachuri L, Zhu Q, Yao S, Ambrosone CB, Kwan ML, Caan BJ, Witte JS, Kushi LH, 't Veer… -
Validation Study on Risk-Reduction Activities after Exposure to a Personalized Breast Cancer Risk-Assessment Education Tool in High-Risk Women in the WISDOM Study.
Research square 2023 Wang T, Che M, Huilgol YS, Keane H, Goodman D, Soonavala R, Ozanne E, Shieh Y, Belkora JK, Fiscalini AS, Athena Breast Health Network Investigators and Advocate Partners, Esserman LJ -
Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy.
Cancer cell 2023 Magbanua MJM, Brown Swigart L, Ahmed Z, Sayaman RW, Renner D, Kalashnikova E, Hirst GL, Yau C, Wolf DM, Li W, Delson AL, Asare S, Liu MC, Albain K, Chien AJ, Forero-Torres A, Isaacs C, Nanda R, … -
Time to Surgery in Breast Cancer-Is Faster Always Better?
JAMA surgery 2023 Mukhtar RA, Esserman LJ -
Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.
Breast cancer research and treatment 2023 Parker BA, Shatsky RA, Schwab RB, Wallace AM, I-SPY 2 Consortium, Wolf DM, Hirst GL, Brown-Swigart L, Esserman LJ, van 't Veer LJ, Ghia EM, Yau C, Kipps TJ -
Guiding principles for the responsible development of artificial intelligence tools for healthcare.
Communications medicine 2023 Badal K, Lee CM, Esserman LJ -
Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy.
Communications medicine 2023 Chitalia R, Miliotis M, Jahani N, Tastsoglou S, McDonald ES, Belenky V, Cohen EA, Newitt D, Van't Veer LJ, Esserman L, Hylton N, DeMichele A, Hatzigeorgiou A, Kontos D -
Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression.
bioRxiv : the preprint server for biology 2023 Nguyen HP, Sheng R, Murray E, Ito Y, Bruck M, Biellak C, An K, Lynce F, Dillon DA, Magbanua MJM, Huppert LA, Hammerlindl H, Esserman L, Rosenbluth JM, Ahituv N -
When Less Can Be More: How the 10-Year Updated Results From the Randomized Controlled AMAROS Trial Should Affect Axillary Management in the Setting of a Positive Node.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Esserman LJ, Ali H, McKenzie T -
Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes.
Plastic and reconstructive surgery. Global open 2023 Barnes LL, Foster R, Mukhtar RA, Esserman LJ, Ewing C, Alvarado M, Wong J, Piper M -
Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.
Breast cancer research and treatment 2023 Magbanua MJM, van 't Veer L, Clark AS, Chien AJ, Boughey JC, Han HS, Wallace A, Beckwith H, Liu MC, Yau C, Wileyto EP, Ordonez A, Solanki TI, Hsiao F, Lee JC, Basu A, Brown Swigart L, Perlmutter J, … -
Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.
Cancer research communications 2022 Glencer AC, Miller PN, Greenwood H, Maldonado Rodas CK, Freimanis R, Basu A, Mukhtar RA, Brabham C, Kim P, Hwang ES, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky AD, Esserman LJ -
Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer.
NPJ breast cancer 2022 Lang JE, Forero-Torres A, Yee D, Yau C, Wolf D, Park J, Parker BA, Chien AJ, Wallace AM, Murthy R, Albain KS, Ellis ED, Beckwith H, Haley BB, Elias AD, Boughey JC, Yung RL, Isaacs C, Clark AS, Han HS,… -
Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
Nature communications 2022 Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, … -
Association of Residual Ductal Carcinoma In Situ With Breast Cancer Recurrence in the Neoadjuvant I-SPY2 Trial.
JAMA surgery 2022 Osdoit M, Yau C, Symmans WF, Boughey JC, Ewing CA, Balassanian R, Chen YY, Krings G, Wallace AM, Zare S, Fadare O, Lancaster R, Wei S, Godellas CV, Tang P, Tuttle TM, Klein M, Sahoo S, Hieken TJ, … -
Informed consent process in the ISPY COVID trial is ethically acceptable.
European journal of internal medicine 2022 Files DC, Esserman L, Liu KD, Calfee CS -
Focal Therapy for Prostate Cancer: Evolutionary Parallels to Breast Cancer Treatment.
The Journal of urology 2022 Labbate CV, Klotz L, Morrow M, Cooperberg M, Esserman L, Eggener SE -
Diffusion-Weighted MRI for Predicting Pathologic Complete Response in Neoadjuvant Immunotherapy.
Cancers 2022 Li W, Le NN, Onishi N, Newitt DC, Wilmes LJ, Gibbs JE, Carmona-Bozo J, Liang J, Partridge SC, Price ER, Joe BN, Kornak J, Magbanua MJM, Nanda R, LeStage B, Esserman LJ, Van't Veer LJ, Hylton NM -
Twenty-Year Benefit From Adjuvant Goserelin and Tamoxifen in Premenopausal Patients With Breast Cancer in a Controlled Randomized Clinical Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022 Johansson A, Dar H, van 't Veer LJ, Tobin NP, Perez-Tenorio G, Nordenskjöld A, Johansson U, Hartman J, Skoog L, Yau C, Benz CC, Esserman LJ, Stål O, Nordenskjöld B, Fornander T, Lindström LS -
Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.
Journal of geriatric oncology 2022 Noordhoek I, Bastiaannet E, de Glas NA, Scheepens J, Esserman LJ, Wesseling J, Scholten AN, Schröder CP, Elias SG, Kroep JR, Portielje JEA, Kleijn M, Liefers GJ -
Why It Is Time to Challenge Entrenched Beliefs About Breast Cancer Screening.
Journal of women's health (2002) 2022 Esserman LJ, Parker BA, LaCroix AZ -
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
Nature communications 2022 Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, … -
Optimizing hormone therapy for breast cancer: Translating gains to the early-stage setting.
Cell reports. Medicine 2022 Chien AJ, Kyalwazi B, Esserman LJ -
I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.
BMJ open 2022 Files DC, Matthay MA, Calfee CS, Aggarwal NR, Asare AL, Beitler JR, Berger PA, Burnham EL, Cimino G, Coleman MH, Crippa A, Discacciati A, Gandotra S, Gibbs KW, Henderson PT, Ittner CAG, Jauregui A, … -
Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies.
Cancer cell 2022 Wolf DM, Yau C, Wulfkuhle J, Brown-Swigart L, Gallagher RI, Lee PRE, Zhu Z, Magbanua MJ, Sayaman R, O'Grady N, Basu A, Delson A, Coppé JP, Lu R, Braun J, I-SPY2 Investigators, Asare SM, Sit L, … -
Treatment Efficacy Score-continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials.
Annals of oncology : official journal of the European Society for Medical Oncology 2022 Marczyk M, Mrukwa A, Yau C, Wolf D, Chen YY, Balassanian R, Nanda R, Parker BA, Krings G, Sattar H, Zeck JC, Albain KS, Boughey JC, Liu MC, Elias AD, Clark AS, Venters SJ, Shad S, Basu A, Asare SM, … -
Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer.
Tomography (Ann Arbor, Mich.) 2022 Le NN, Li W, Onishi N, Newitt DC, Gibbs JE, Wilmes LJ, Kornak J, Partridge SC, LeStage B, Price ER, Joe BN, Esserman LJ, Hylton NM -
Association of Residual Cancer Burden After Neoadjuvant Therapy and Event-Free Survival in Breast Cancer-Reply.
JAMA oncology 2022 Mukhtar R, Symmans WF, Esserman LJ -
Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature.
International journal of cancer 2022 Johansson A, Yu NY, Iftimi A, Tobin NP, van 't Veer L, Nordenskjöld B, Benz CC, Fornander T, Perez-Tenorio G, Stål O, Esserman LJ, Yau C, Lindström LS -
Survivorship after neoadjuvant chemotherapy - Authors' reply.
The Lancet. Oncology 2022 Yau C, Osdoit M, Esserman LJ, Symmans WF -
Evaluation of the Pathways for Survivors Program to Address Breast Cancer Survivorship-Associated Distress: Survey Study.
JMIR cancer 2022 Umashankar S, Mamounas ME, Matthys M, Hadeler EK, Wong EC, Hicks G, Hwang J, Chien AJ, Rugo HS, Hamolsky D, Esserman L, Melisko M -
Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022 Lopes Cardozo JMN, Drukker CA, Rutgers EJT, Schmidt MK, Glas AM, Witteveen A, Cardoso F, Piccart M, Esserman LJ, Poncet C, van 't Veer LJ -
The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.
NPJ breast cancer 2022 Nachmanson D, Officer A, Mori H, Gordon J, Evans MF, Steward J, Yao H, O'Keefe T, Hasteh F, Stein GS, Jepsen K, Weaver DL, Hirst GL, Sprague BL, Esserman LJ, Borowsky AD, Stein JL, Harismendy O -
The incidence of discordant clinical and genomic risk in patients with invasive lobular or ductal carcinoma of the breast: a National Cancer Database Study.
NPJ breast cancer 2021 Abel MK, Shui AM, Melisko M, Chien AJ, Yoshida EJ, Lancaster EM, Van 't Veer L, Esserman LJ, Mukhtar RA -
Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.
The Lancet. Oncology 2021 Yau C, Osdoit M, van der Noordaa M, Shad S, Wei J, de Croze D, Hamy AS, Laé M, Reyal F, Sonke GS, Steenbruggen TG, van Seijen M, Wesseling J, Martín M, Del Monte-Millán M, López-Tarruella S, I-SPY 2 … -
A case-case analysis of women with breast cancer: predictors of interval vs screen-detected cancer.
Breast cancer research and treatment 2021 Dreher N, Matthys M, Hadeler E, Shieh Y, Acerbi I, McAuley FM, Melisko M, Eklund M, Tice JA, Esserman LJ, Veer LJV -
Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial.
Nature communications 2021 Clark AS, Yau C, Wolf DM, Petricoin EF, van 't Veer LJ, Yee D, Moulder SL, Wallace AM, Chien AJ, Isaacs C, Boughey JC, Albain KS, Kemmer K, Haley BB, Han HS, Forero-Torres A, Elias A, Lang JE, Ellis … -
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer.
Nature communications 2021 Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A -
Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.
JAMA oncology 2021 Symmans WF, Yau C, Chen YY, Balassanian R, Klein ME, Pusztai L, Nanda R, Parker BA, Datnow B, Krings G, Wei S, Feldman MD, Duan X, Chen B, Sattar H, Khazai L, Zeck JC, Sams S, Mhawech-Fauceglia P, … -
Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST?
NPJ breast cancer 2021 Abel MK, Melisko ME, Rugo HS, Chien AJ, Diaz I, Levine JK, Griffin A, McGuire J, Esserman LJ, Borno HT, Mukhtar RA -
Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.
NPJ breast cancer 2021 Yee D, Isaacs C, Wolf DM, Yau C, Haluska P, Giridhar KV, Forero-Torres A, Jo Chien A, Wallace AM, Pusztai L, Albain KS, Ellis ED, Beckwith H, Haley BB, Elias AD, Boughey JC, Kemmer K, Yung RL, … -
Pre-Appointment Nurse Navigation: Patient-Centered Findings From a Survey of Patients With Breast Cancer.
Clinical journal of oncology nursing 2021 Wang T, Huilgol YS, Black J, D'Andrea C, James J, Northrop A, Belkora J, Esserman LJ -
Health screening needs independent regular re-evaluation.
BMJ (Clinical research ed.) 2021 Ropers FG, Barratt A, Wilt TJ, Nicholls SG, Taylor-Phillips S, Kramer BS, Esserman LJ, Norris SL, Gibson LM, Harris RP, Carter SM, Jacklyn G, Jørgensen KJ -
Trigger point injection for post-mastectomy pain: a simple intervention with high rate of long-term relief.
NPJ breast cancer 2021 Khoury AL, Keane H, Varghese F, Hosseini A, Mukhtar R, Eder SE, Weinstein PR, Esserman LJ -
The WISDOM study: a new approach to screening can and should be tested.
Breast cancer research and treatment 2021 Esserman L, Eklund M, Veer LV, Shieh Y, Tice J, Ziv E, Blanco A, Kaplan C, Hiatt R, Fiscalini AS, Yau C, Scheuner M, Naeim A, Wenger N, Lee V, Heditsian D, Brain S, Parker BA, LaCroix AZ, Madlensky L,… -
The use of neoadjuvant therapy to further personalize breast cancer treatment.
Clinical advances in hematology & oncology : H&O 2021 Esserman LJ -
Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response.
Radiology 2021 Onishi N, Li W, Newitt DC, Harnish RJ, Strand F, Nguyen AA, Arasu VA, Gibbs J, Jones EF, Wilmes LJ, Kornak J, Joe BN, Price ER, Ojeda-Fournier H, Eghtedari M, Zamora KW, Woodard S, Umphrey HR, Nelson … -
Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry.
NPJ breast cancer 2021 Huilgol YS, Keane H, Shieh Y, Hiatt RA, Tice JA, Madlensky L, Sabacan L, Fiscalini AS, Ziv E, Acerbi I, Che M, Anton-Culver H, Borowsky AD, Hunt S, Naeim A, Parker BA, van 't Veer LJ, Athena Breast … -
Authors' Reply: To the Letter to the Editor by Groheux et al.
Journal of the National Comprehensive Cancer Network : JNCCN 2021 Heath CL, Esserman LJ, Flavell RR, Melisko ME -
Advancing precision medicine for acute respiratory distress syndrome.
The Lancet. Respiratory medicine 2021 Beitler JR, Thompson BT, Baron RM, Bastarache JA, Denlinger LC, Esserman L, Gong MN, LaVange LM, Lewis RJ, Marshall JC, Martin TR, McAuley DF, Meyer NJ, Moss M, Reineck LA, Rubin E, Schmidt EP, … -
Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial.
NPJ breast cancer 2021 Keane H, Huilgol YS, Shieh Y, Tice JA, Belkora J, Sepucha K, Shibley WP, Wang T, Che M, Goodman D, Ozanne E, Fiscalini AS, Esserman LJ -
Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial.
Cancer cell 2021 Pusztai L, Yau C, Wolf DM, Han HS, Du L, Wallace AM, String-Reasor E, Boughey JC, Chien AJ, Elias AD, Beckwith H, Nanda R, Albain KS, Clark AS, Kemmer K, Kalinsky K, Isaacs C, Thomas A, Shatsky R, … -
Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies.
American journal of surgery 2021 Hewitt KC, Miller P, Piper M, Prionas N, Son JD, Alvarado M, Esserman LJ, Wong JM, Ewing C, Mukhtar RA -
PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial.
JAMIA open 2021 O'Grady N, Gibbs DL, Abdilleh K, Asare A, Asare S, Venters S, Brown-Swigart L, Hirst GL, Wolf D, Yau C, van 't Veer LJ, Esserman L, Basu A -
Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial.
JAMA network open 2021 Dar H, Johansson A, Nordenskjöld A, Iftimi A, Yau C, Perez-Tenorio G, Benz C, Nordenskjöld B, Stål O, Esserman LJ, Fornander T, Lindström LS -
Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.
NPJ breast cancer 2021 Glencer AC, Wong JM, Hylton NM, Krings G, McCune E, Rothschild HT, Loveday TA, Alvarado MD, Esserman LJ, Campbell MJ -
Incorporation of Patient-Reported Outcomes Measurement Information System to assess quality of life among patients with breast cancer initiating care at an academic center.
Cancer 2021 Matthys MB, Dempsey AM, Melisko ME, Dreher N, Che ML, Van't Veer LJ, Esserman LJ, Basu A -
Mask-Guided Convolutional Neural Network for Breast Tumor Prognostic Outcome Prediction on 3D DCE-MR Images.
Journal of digital imaging 2021 Liu G, Mitra D, Jones EF, Franc BL, Behr SC, Nguyen A, Bolouri MS, Wisner DJ, Joe BN, Esserman LJ, Hylton NM, Seo Y -
Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk.
NPJ breast cancer 2021 Magbanua MJM, Li W, Wolf DM, Yau C, Hirst GL, Swigart LB, Newitt DC, Gibbs J, Delson AL, Kalashnikova E, Aleshin A, Zimmermann B, Chien AJ, Tripathy D, Esserman L, Hylton N, van 't Veer L -
Accuracy of breast MRI in evaluating nodal status after neoadjuvant therapy in invasive lobular carcinoma.
NPJ breast cancer 2021 Abel MK, Greenwood H, Kelil T, Guo R, Brabham C, Hylton N, Wong J, Alvarado M, Ewing C, Esserman LJ, Boughey JC, Mukhtar RA -
Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy.
Annals of oncology : official journal of the European Society for Medical Oncology 2021 Du L, Yau C, Brown-Swigart L, Gould R, Krings G, Hirst GL, Bedrosian I, Layman RM, Carter JM, Klein M, Venters S, Shad S, van der Noordaa M, Chien AJ, Haddad T, Isaacs C, Pusztai L, Albain K, Nanda R,… -
Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.
Journal of mammary gland biology and neoplasia 2021 Mori H, Bolen J, Schuetter L, Massion P, Hoyt CC, VandenBerg S, Esserman L, Borowsky AD, Campbell MJ -
Contralateral prophylactic mastectomy: A narrative review of the evidence and acceptability.
Breast (Edinburgh, Scotland) 2021 Scheepens JCC, Veer LV', Esserman L, Belkora J, Mukhtar RA -
A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Hansen KS, Ghersin H, Piper M, Tavakol M, Lee B, Esserman LJ, Roberts JP, Freise C, Ascher NL, Mukhtar RA -
Characterization of Oligometastatic Disease in a Real-World Nationwide Cohort of 3447 Patients With de Novo Metastatic Breast Cancer.
JNCI cancer spectrum 2021 Steenbruggen TG, Schaapveld M, Horlings HM, Sanders J, Hogewoning SJ, Lips EH, Vrancken Peeters MT, Kok NF, Wiersma T, Esserman L, van 't Veer LJ, Linn SC, Siesling S, Sonke GS -
Accuracy of sentinel lymph node biopsy in invasive lobular carcinoma of the breast: Factors associated with false negatives.
The breast journal 2021 Mukhtar RA, Brabham CE, Guo R, Abel MK, Wong J, Ewing C, Esserman LJ, Alvarado M -
MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit.
NPJ breast cancer 2021 Løkkegaard S, Elias D, Alves CL, Bennetzen MV, Lænkholm AV, Bak M, Gjerstorff MF, Johansen LE, Vever H, Bjerre C, Kirkegaard T, Nordenskjöld B, Fornander T, Stål O, Lindström LS, Esserman LJ, … -
Prime Time for Consultation Audio Recordings: Supporting Shared Decision Making During and After the COVID-19 Era.
JCO oncology practice 2020 Kwon DH, Aggarwal RR, Esserman LJ, Belkora JK -
Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.
Scientific reports 2020 Hathi DK, Li W, Seo Y, Flavell RR, Kornak J, Franc BL, Joe BN, Esserman LJ, Hylton NM, Jones EF -
Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL.
NPJ breast cancer 2020 Li W, Newitt DC, Gibbs J, Wilmes LJ, Jones EF, Arasu VA, Strand F, Onishi N, Nguyen AA, Kornak J, Joe BN, Price ER, Ojeda-Fournier H, Eghtedari M, Zamora KW, Woodard SA, Umphrey H, Bernreuter W, … -
Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival.
Annals of oncology : official journal of the European Society for Medical Oncology 2020 Magbanua MJM, Swigart LB, Wu HT, Hirst GL, Yau C, Wolf DM, Tin A, Salari R, Shchegrova S, Pawar H, Delson AL, DeMichele A, Liu MC, Chien AJ, Tripathy D, Asare S, Lin CJ, Billings P, Aleshin A, Sethi H… -
Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.
BMC medical genomics 2020 Nachmanson D, Steward J, Yao H, Officer A, Jeong E, O'Keefe TJ, Hasteh F, Jepsen K, Hirst GL, Esserman LJ, Borowsky AD, Harismendy O -
Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis.
Journal of the National Comprehensive Cancer Network : JNCCN 2020 Hyland CJ, Varghese F, Yau C, Beckwith H, Khoury K, Varnado W, Hirst GL, Flavell RR, Chien AJ, Yee D, Isaacs CJ, Forero-Torres A, Esserman LJ, Melisko ME -
Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement.
Nature reviews. Clinical oncology 2020 Pashayan N, Antoniou AC, Ivanus U, Esserman LJ, Easton DF, French D, Sroczynski G, Hall P, Cuzick J, Evans DG, Simard J, Garcia-Closas M, Schmutzler R, Wegwarth O, Pharoah P, Moorthie S, De … -
The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology.
NPJ breast cancer 2020 Basu A, Philip EJ, Dewitt B, Hanmer J, Chattopadhyay A, Yau C, Melisko ME, Esserman LJ -
The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020 Hewitt K, Son J, Glencer A, Borowsky AD, Cooperberg MR, Esserman LJ -
Oncological Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of the Breast: A 20-Year Institutional Experience.
Annals of surgical oncology 2020 Son JD, Piper M, Hewitt K, Alvarado M, Esserman LJ, Ewing C, Wong JM, Mukhtar RA -
Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial.
NPJ breast cancer 2020 Wolf DM, Yau C, Wulfkuhle J, Brown-Swigart L, Gallagher RI, Magbanua MJM, O'Grady N, Hirst G, I-SPY 2 TRIAL Investigators, Asare S, Tripathy D, Berry D, Esserman L, Chien AJ, Petricoin EF, van 't Veer… -
Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.
JAMA oncology 2020 I-SPY2 Trial Consortium, Yee D, DeMichele AM, Yau C, Isaacs C, Symmans WF, Albain KS, Chen YY, Krings G, Wei S, Harada S, Datnow B, Fadare O, Klein M, Pambuccian S, Chen B, Adamson K, Sams S, Mhawech-… -
Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.
Surgery 2020 Sharib J, Esserman L, Koay EJ, Maitra A, Shen Y, Kirkwood KS, Ozanne EM -
Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.
Journal of breast imaging 2020 Arasu VA, Kim P, Li W, Strand F, McHargue C, Harnish R, Newitt DC, Jones EF, Glymour MM, Kornak J, Esserman LJ, Hylton NM, ISPY2 investigators -
Evaluating the impact of axillary dissection on recurrence-free survival by extent of nodal disease in invasive lobular carcinoma of the breast.
Breast cancer research and treatment 2020 Abel MK, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Park C, Mukhtar RA -
Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater.
American journal of surgery 2020 Abel MK, Brabham CE, Guo R, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Mukhtar RA -
Personalized early detection and prevention of breast cancer: ENVISION consensus statement.
Nature reviews. Clinical oncology 2020 Pashayan N, Antoniou AC, Ivanus U, Esserman LJ, Easton DF, French D, Sroczynski G, Hall P, Cuzick J, Evans DG, Simard J, Garcia-Closas M, Schmutzler R, Wegwarth O, Pharoah P, Moorthie S, De … -
Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy.
Cancers 2020 Jones EF, Hathi DK, Freimanis R, Mukhtar RA, Chien AJ, Esserman LJ, Van't Veer LJ, Joe BN, Hylton NM -
Comparison of Segmentation Methods in Assessing Background Parenchymal Enhancement as a Biomarker for Response to Neoadjuvant Therapy.
Tomography (Ann Arbor, Mich.) 2020 Nguyen AA, Arasu VA, Strand F, Li W, Onishi N, Gibbs J, Jones EF, Joe BN, Esserman LJ, Newitt DC, Hylton NM -
Impact of MRI Protocol Adherence on Prediction of Pathological Complete Response in the I-SPY 2 Neoadjuvant Breast Cancer Trial.
Tomography (Ann Arbor, Mich.) 2020 Onishi N, Li W, Gibbs J, Wilmes LJ, Nguyen A, Jones EF, Arasu V, Kornak J, Joe BN, Esserman LJ, Newitt DC, Hylton NM -
Tumor Sphericity Predicts Response in Neoadjuvant Chemotherapy for Invasive Breast Cancer.
Tomography (Ann Arbor, Mich.) 2020 Li W, Newitt DC, Yun B, Jones EF, Arasu V, Wilmes LJ, Gibbs J, Nguyen AA, Onishi N, Kornak J, Joe BN, Esserman LJ, Hylton NM -
Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial.
JAMA oncology 2020 Nanda R, Liu MC, Yau C, Shatsky R, Pusztai L, Wallace A, Chien AJ, Forero-Torres A, Ellis E, Han H, Clark A, Albain K, Boughey JC, Jaskowiak NT, Elias A, Isaacs C, Kemmer K, Helsten T, Majure M, … -
Personalization of Treatment is the Way Forward in Care and Trials.
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Esserman LJ -
Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival.
Breast cancer research and treatment 2020 Mukhtar RA, Krings G, Chen YY, Mamounas ME, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Rugo H -
Response to Carter et al.
JNCI cancer spectrum 2020 Eklund M, Broglio K, Yau C, Connor JT, Fiscalini AS, Esserman LJ -
Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Hwang ES, Hyslop T, Hendrix LH, Duong S, Bedrosian I, Price E, Caudle A, Hieken T, Guenther J, Hudis CA, Winer E, Lyss AP, Dickson-Witmer D, Hoefer R, Ollila DW, Hardman T, Marks J, Chen YY, Krings G,… -
We need more evidence to answer questions about screening.
Nature 2020 Esserman L -
Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.
Journal of the American College of Surgeons 2019 Cao CX, Sharib JM, Blanco AM, Goldberg D, Bracci P, Mukhtar RA, Esserman LJ, Kirkwood KS -
Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast.
NPJ breast cancer 2019 Piper ML, Wong J, Fahrner-Scott K, Ewing C, Alvarado M, Esserman LJ, Mukhtar RA -
Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.
JAMA oncology 2019 Yu NY, Iftimi A, Yau C, Tobin NP, van 't Veer L, Hoadley KA, Benz CC, Nordenskjöld B, Fornander T, Stål O, Czene K, Esserman LJ, Lindström LS -
A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel.
NPJ breast cancer 2019 Piawah S, Hyland C, Umetsu SE, Esserman LJ, Rugo HS, Chien AJ -
Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Magbanua MJM, Yau C, Wolf DM, Lee JS, Chattopadhyay A, Scott JH, Bowlby-Yoder E, Hwang ES, Alvarado M, Ewing CA, Delson AL, Van't Veer LJ, Esserman L, Park JW -
Fitbit Usage in Patients With Breast Cancer Undergoing Chemotherapy.
Clinical breast cancer 2019 Dreher N, Hadeler EK, Hartman SJ, Wong EC, Acerbi I, Rugo HS, Majure MC, Chien AJ, Esserman LJ, Melisko ME -
Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.
Journal of magnetic resonance imaging : JMRI 2019 Li W, Newitt DC, Wilmes LJ, Jones EF, Arasu V, Gibbs J, La Yun B, Li E, Partridge SC, Kornak J, I-SPY 2 Consortium, Esserman LJ, Hylton NM -
Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol.
NPJ breast cancer 2019 Jones EF, Ray KM, Li W, Chien AJ, Mukhtar RA, Esserman LJ, Franc BL, Seo Y, Pampaloni MH, Joe BN, Hylton NM -
A response to "Personalised medicine and population health: breast and ovarian cancer".
Human genetics 2019 Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, … -
MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2019 Chien AJ, Tripathy D, Albain KS, Symmans WF, Rugo HS, Melisko ME, Wallace AM, Schwab R, Helsten T, Forero-Torres A, Stringer-Reasor E, Ellis ED, Kaplan HG, Nanda R, Jaskowiak N, Murthy R, Godellas C, … -
Should we rename low risk cancers?
BMJ (Clinical research ed.) 2019 Esserman LJ, Varma M -
Evaluation of National Comprehensive Cancer Network guideline-based Tool for Risk Assessment for breast and ovarian Cancer (N-TRAC): A patient-reported survey for genetic high-risk assessment for breast and ovarian cancers in women.
Journal of genetic counseling 2019 Ozanne EM, Howe R, Mallinson D, Esserman L, Van't Veer LJ, Kaplan CP -
The WISDOM Personalized Breast Cancer Screening Trial: Simulation Study to Assess Potential Bias and Analytic Approaches.
JNCI cancer spectrum 2019 Eklund M, Broglio K, Yau C, Connor JT, Stover Fiscalini A, Esserman LJ -
Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.
NPJ breast cancer 2019 Boughey JC, Alvarado MD, Lancaster RB, Symmans WF, Mukhtar R, Wong JM, Ewing CA, Potter DA, Tuttle TM, Hieken TJ, Carter JM, Jakub JW, Kaplan HG, Buchanan CL, Jaskowiak NT, Sattar HA, Mueller J, Nanda… -
Functional Status and Survival After Breast Cancer Surgery in Nursing Home Residents.
JAMA surgery 2018 Tang V, Zhao S, Boscardin J, Sudore R, Covinsky K, Walter LC, Esserman L, Mukhtar R, Finlayson E -
Precision risk-based screening might maximize benefit and minimize harm.
Nature reviews. Clinical oncology 2018 Esserman LJ, LaCroix AZ -
Test-retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial.
Journal of magnetic resonance imaging : JMRI 2018 Newitt DC, Zhang Z, Gibbs JE, Partridge SC, Chenevert TL, Rosen MA, Bolan PJ, Marques HS, Aliu S, Li W, Cimino L, Joe BN, Umphrey H, Ojeda-Fournier H, Dogan B, Oh K, Abe H, Drukteinis J, Esserman LJ, … -
Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.
NPJ breast cancer 2018 Magbanua MJM, Rugo HS, Hauranieh L, Roy R, Scott JH, Lee JC, Hsiao F, Sosa EV, Van't Veer L, Esserman LJ, Park JW -
Diffusion-weighted MRI Findings Predict Pathologic Response in Neoadjuvant Treatment of Breast Cancer: The ACRIN 6698 Multicenter Trial.
Radiology 2018 Partridge SC, Zhang Z, Newitt DC, Gibbs JE, Chenevert TL, Rosen MA, Bolan PJ, Marques HS, Romanoff J, Cimino L, Joe BN, Umphrey HR, Ojeda-Fournier H, Dogan B, Oh K, Abe H, Drukteinis JS, Esserman LJ, … -
Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.
NPJ breast cancer 2018 Boughey JC, Alvarado MD, Lancaster RB, Fraser Symmans W, Mukhtar R, Wong JM, Ewing CA, Potter DA, Tuttle TM, Hieken TJ, Carter JM, Jakub JW, Kaplan HG, Buchanan CL, Jaskowiak NT, Sattar HA, Mueller J,… -
Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.
JCO precision oncology 2018 Wulfkuhle JD, Yau C, Wolf DM, Vis DJ, Gallagher RI, Brown-Swigart L, Hirst G, Voest EE, DeMichele A, Hylton N, Symmans F, Yee D, Esserman L, Berry D, Liu M, Park JW, Wessels LFA, Van't Veer L, … -
Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.
NPJ breast cancer 2018 Huang SY, Franc BL, Harnish RJ, Liu G, Mitra D, Copeland TP, Arasu VA, Kornak J, Jones EF, Behr SC, Hylton NM, Price ER, Esserman L, Seo Y -
Breast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 Patients.
Annals of surgical oncology 2018 Mukhtar RA, Wong J, Piper M, Zhu Z, Fahrner-Scott K, Mamounas M, Sbitany H, Alvarado M, Foster R, Ewing C, Esserman L -
The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.
Future oncology (London, England) 2018 Mustoe MM, Lee CM, Melisko ME, Esserman LJ, Rugo HS -
Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.
Journal of the National Cancer Institute 2018 Lindström LS, Yau C, Czene K, Thompson CK, Hoadley KA, Van't Veer LJ, Balassanian R, Bishop JW, Carpenter PM, Chen YY, Datnow B, Hasteh F, Krings G, Lin F, Zhang Y, Nordenskjöld B, Stål O, Benz CC, … -
Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.
Journal of the National Cancer Institute 2018 Bidard FC, Michiels S, Riethdorf S, Mueller V, Esserman LJ, Lucci A, Naume B, Horiguchi J, Gisbert-Criado R, Sleijfer S, Toi M, Garcia-Saenz JA, Hartkopf A, Generali D, Rothé F, Smerage J, Muinelo-… -
Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.
BJS open 2018 Winters ZE, Horsnell J, Elvers KT, Maxwell AJ, Jones LJ, Shaaban AM, Schmid P, Williams NR, Beswick A, Greenwood R, Ingram JC, Saunders C, Vaidya JS, Esserman L, Jatoi I, Brunt AM -
MRI, Clinical Examination, and Mammography for Preoperative Assessment of Residual Disease and Pathologic Complete Response After Neoadjuvant Chemotherapy for Breast Cancer: ACRIN 6657 Trial.
AJR. American journal of roentgenology 2018 Scheel JR, Kim E, Partridge SC, Lehman CD, Rosen MA, Bernreuter WK, Pisano ED, Marques HS, Morris EA, Weatherall PT, Polin SM, Newstead GM, Esserman LJ, Schnall MD, Hylton NM, ACRIN 6657 Trial Team … -
Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy.
BMC anesthesiology 2018 Chiu C, Aleshi P, Esserman LJ, Inglis-Arkell C, Yap E, Whitlock EL, Harbell MW -
Initial Clinical Experience With an Inducible Magnetic Seed System for Preoperative Breast Lesion Localization.
AJR. American journal of roentgenology 2018 Price ER, Khoury AL, Esserman LJ, Joe BN, Alvarado MD -
Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction.
Annals of plastic surgery 2018 Peled AW, Sears M, Wang F, Foster RD, Alvarado M, Wong J, Ewing CA, Sbitany H, Esserman LJ, Fowble B -
Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.
Journal of medical imaging (Bellingham, Wash.) 2017 Olshen A, Wolf D, Jones EF, Newitt D, van ‘t Veer LJ, Yau C, Esserman L, Wulfkuhle JD, Gallagher RI, Singer L, Petricoin EF, Hylton N, Park CC -
Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.
Oncotarget 2017 Kwong A, Ho JCW, Shin VY, Kurian AW, Tai E, Esserman LJ, Weitzel JN, Lin PH, Field M, Domchek SM, Lo J, Ngan HYS, Ma ESK, Chan TL, Ford JM -
Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.
The New England journal of medicine 2017 DeMichele A, Yee D, Esserman L -
Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.
JAMA oncology 2017 Esserman LJ, Yau C, Thompson CK, van 't Veer LJ, Borowsky AD, Hoadley KA, Tobin NP, Nordenskjöld B, Fornander T, Stål O, Benz CC, Lindström LS -
The value of embedding: integrated palliative care for patients with metastatic breast cancer.
Breast cancer research and treatment 2017 Rabow M, Small R, Jow A, Majure M, Chien A, Melisko M, Belkora J, Esserman LJ, Rugo H -
Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.
Breast cancer research and treatment 2017 Rice BA, Ver Hoeve ES, DeLuca AN, Esserman LJ, Rugo HS, Melisko ME -
The WISDOM Study: breaking the deadlock in the breast cancer screening debate.
NPJ breast cancer 2017 Esserman LJ, WISDOM Study and Athena Investigators -
Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.
Breast cancer research : BCR 2017 Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, … -
DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.
NPJ breast cancer 2017 Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, … -
Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.
Breast cancer research and treatment 2017 van 't Veer LJ, Yau C, Yu NY, Benz CC, Nordenskjöld B, Fornander T, Stål O, Esserman LJ, Lindström LS -
Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.
Breast cancer research and treatment 2017 Chien AJ, Chambers J, Mcauley F, Kaplan T, Letourneau J, Hwang J, Kim MO, Melisko ME, Rugo HS, Esserman LJ, Rosen MP -
Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women.
Clinical breast cancer 2017 Fowble B, Jairam AK, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Park C, Lazar A -
Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Breast cancer research and treatment 2017 Campbell JI, Yau C, Krass P, Moore D, Carey LA, Au A, Chhieng D, Giri D, Livasy C, Mies C, Rabban J, Sarode VR, Singh B, Esserman L, Chen YY -
Receptor activator of nuclear factor kappa B (RANK) expression in primary breast cancer correlates with recurrence-free survival and development of bone metastases in I-SPY1 (CALGB 150007/150012; ACRIN 6657).
Breast cancer research and treatment 2017 Vidula N, Yau C, Li J, Esserman LJ, Rugo HS -
Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.
Breast cancer research and treatment 2017 Chien AJ, Chambers J, Mcauley F, Kaplan T, Letourneau J, Hwang J, Kim MO, Melisko ME, Rugo HS, Esserman LJ, Rosen MP -
Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.
JAMA oncology 2017 Melisko ME, Goldman ME, Hwang J, De Luca A, Fang S, Esserman LJ, Chien AJ, Park JW, Rugo HS -
Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.
JAMA 2017 Rugo HS, Klein P, Melin SA, Hurvitz SA, Melisko ME, Moore A, Park G, Mitchel J, Bågeman E, D'Agostino RB, Ver Hoeve ES, Esserman L, Cigler T -
Precision surgery and avoiding over-treatment.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2017 Hosseini A, Khoury AL, Esserman LJ -
Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.
Journal of the National Cancer Institute 2017 Shieh Y, Eklund M, Madlensky L, Sawyer SD, Thompson CK, Stover Fiscalini A, Ziv E, Van't Veer LJ, Esserman LJ, Tice JA, Athena Breast Health Network Investigators -
Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Ellis MJ, Suman VJ, Hoog J, Goncalves R, Sanati S, Creighton CJ, DeSchryver K, Crouch E, Brink A, Watson M, Luo J, Tao Y, Barnes M, Dowsett M, Budd GT, Winer E, Silverman P, Esserman L, Carey L, Ma CX… -
Dedicated Breast Positron Emission Tomography for the Evaluation of Early Response to Neoadjuvant Chemotherapy in Breast Cancer.
Clinical breast cancer 2016 Jones EF, Ray KM, Li W, Seo Y, Franc BL, Chien AJ, Esserman LJ, Pampaloni MH, Joe BN, Hylton NM -
MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial.
Journal of magnetic resonance imaging : JMRI 2016 Bolan PJ, Kim E, Herman BA, Newstead GM, Rosen MA, Schnall MD, Pisano ED, Weatherall PT, Morris EA, Lehman CD, Garwood M, Nelson MT, Yee D, Polin SM, Esserman LJ, Gatsonis CA, Metzger GJ, Newitt DC, … -
Do Prolonged Prophylactic Antibiotics Reduce the Incidence of Surgical-Site Infections in Immediate Prosthetic Breast Reconstruction?
Plastic and reconstructive surgery 2016 Wang F, Chin R, Piper M, Esserman L, Sbitany H -
Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.
Tomography (Ann Arbor, Mich.) 2016 Li W, Arasu V, Newitt DC, Jones EF, Wilmes L, Gibbs J, Kornak J, Joe BN, Esserman LJ, Hylton NM, ACRIN 6657 Trial Team and I-SPY Investigators Network -
Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.
Breast cancer research and treatment 2016 Amara D, Wolf DM, van 't Veer L, Esserman L, Campbell M, Yau C -
Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.
Breast cancer research and treatment 2016 Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L -
Adaptive Randomization of Neratinib in Early Breast Cancer.
The New England journal of medicine 2016 Berry D, Esserman L -
PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms.
Clinical pharmacology and therapeutics 2016 Trusheim MR, Shrier AA, Antonijevic Z, Beckman RA, Campbell RK, Chen C, Flaherty KT, Loewy J, Lacombe D, Madhavan S, Selker HP, Esserman LJ -
The I-SPY approach to drug development.
Clinical advances in hematology & oncology : H&O 2016 Esserman L -
Laura Esserman and Ian Thompson Discuss Strategies for Screening and Treatment of Early-Stage Cancers, and How Clinicians Can Learn From Each Other's Experiences.
Oncology (Williston Park, N.Y.) 2016 Esserman LJ, Thompson IM -
The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016 Mukhtar RA, Piper ML, Freise C, Van't Veer LJ, Baehner FL, Esserman LJ -
Adaptive Randomization of Neratinib in Early Breast Cancer.
The New England journal of medicine 2016 Park JW, Liu MC, Yee D, Yau C, van 't Veer LJ, Symmans WF, Paoloni M, Perlmutter J, Hylton NM, Hogarth M, DeMichele A, Buxton MB, Chien AJ, Wallace AM, Boughey JC, Haddad TC, Chui SY, Kemmer KA, … -
Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.
The New England journal of medicine 2016 Rugo HS, Olopade OI, DeMichele A, Yau C, van 't Veer LJ, Buxton MB, Hogarth M, Hylton NM, Paoloni M, Perlmutter J, Symmans WF, Yee D, Chien AJ, Wallace AM, Kaplan HG, Boughey JC, Haddad TC, Albain KS,… -
When Less Is Better, but Physicians Are Afraid Not to Intervene.
JAMA internal medicine 2016 Esserman L -
Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.
Proteomics. Clinical applications 2016 Katchman BA, Barderas R, Alam R, Chowell D, Field MS, Esserman LJ, Wallstrom G, LaBaer J, Cramer DW, Hollingsworth MA, Anderson KS -
Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.
Annals of plastic surgery 2016 Piper ML, Esserman LJ, Sbitany H, Peled AW -
Population-based screening for cancer: hope and hype.
Nature reviews. Clinical oncology 2016 Shieh Y, Eklund M, Sawaya GF, Black WC, Kramer BS, Esserman LJ -
When the Gold Standard Loses Its Luster, Perhaps It Is Time to Change Nomenclature.
Annals of internal medicine 2016 Borowsky A, Esserman L -
Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ-Reply.
JAMA oncology 2016 Esserman L, Yau C -
Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.
PloS one 2016 Lo WC, Li W, Jones EF, Newitt DC, Kornak J, Wilmes LJ, Esserman LJ, Hylton NM -
A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.
Breast cancer research and treatment 2016 Chien AJ, Cockerill A, Fancourt C, Schmidt E, Moasser MM, Rugo HS, Melisko ME, Ko AH, Kelley RK, Korn WM, Esserman LJ, van't Veer L, Yau C, Wolf DM, Munster PN -
Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?
Breast (Edinburgh, Scotland) 2016 Winters ZE, Horsnell J, Schmid P, Jones JL, Shaaban A, Maxwell AJ, Williams N, Esserman L, Jatoi I, Brunt AM, MIAMI (Multiple Ipsilateral breast conserving surgery versus mastectomy) Trial Management … -
Detection of ductal carcinoma in situ and subsequent interval cancers.
BMJ (Clinical research ed.) 2016 Shieh Y, Eklund M, Esserman L -
CLINICAL DECISIONS. Ductal Carcinoma In Situ.
The New England journal of medicine 2016 Merrill AL, Esserman L, Morrow M -
Less Is More: The Evolving Surgical Approach to Breast Cancer.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2016 Esserman L, Gallant E, Alvarado M -
Neoadjuvant as Future for Drug Development in Breast Cancer--Response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 DeMichele A, Yee D, Paoloni M, Berry D, Esserman LJ, I-SPY2 Investigators -
The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction.
Plastic and reconstructive surgery 2016 Wang F, Peled AW, Chin R, Fowble B, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H -
Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation.
Annals of plastic surgery 2016 Sbitany H, Wang F, Peled AW, Alvarado M, Ewing CA, Esserman LJ, Foster RD -
Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.
Annals of surgical oncology 2015 Johnson J, Esserman L, Ewing C, Alvarado M, Park C, Fowble B -
Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL.
Radiology 2015 Hylton NM, Gatsonis CA, Rosen MA, Lehman CD, Newitt DC, Partridge SC, Bernreuter WK, Pisano ED, Morris EA, Weatherall PT, Polin SM, Newstead GM, Marques HS, Esserman LJ, Schnall MD, ACRIN 6657 Trial … -
Rethinking the Standard for Ductal Carcinoma In Situ Treatment.
JAMA oncology 2015 Esserman L, Yau C -
Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer.
Annals of surgical oncology 2015 Wang F, Amara D, Peled AW, Sbitany H, Foster RD, Ewing CA, Alvarado M, Esserman LJ -
Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer.
Breast cancer research and treatment 2015 Chien AJ, Duralde E, Hwang R, Tsung K, Kao CN, Rugo HS, Melisko ME, Esserman LJ, Munster PN, Cedars M, Kerlikowske K, McCulloch CE, Rosen MP -
Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2015 Provenzano E, Bossuyt V, Viale G, Cameron D, Badve S, Denkert C, MacGrogan G, Penault-Llorca F, Boughey J, Curigliano G, Dixon JM, Esserman L, Fastner G, Kuehn T, Peintinger F, von Minckwitz G, White … -
How to use magnetic resonance imaging following neoadjuvant chemotherapy in locally advanced breast cancer.
World journal of clinical cases 2015 Price ER, Wong J, Mukhtar R, Hylton N, Esserman LJ -
Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease?
Annals of surgical oncology 2015 Peled AW, Wang F, Foster RD, Alvarado M, Ewing CA, Sbitany H, Esserman LJ -
In Regard to Hepel and Wazer.
International journal of radiation oncology, biology, physics 2015 Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M -
Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care.
Journal of the National Comprehensive Cancer Network : JNCCN 2015 Mukhtar RA, Wong JM, Esserman LJ -
Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.
Breast cancer research : BCR 2015 Magbanua MJ, Wolf DM, Yau C, Davis SE, Crothers J, Au A, Haqq CM, Livasy C, Rugo HS, I-SPY 1 TRIAL Investigators, Esserman L, Park JW, van 't Veer LJ -
Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management.
Annals of surgical oncology 2015 Amara D, Peled AW, Wang F, Ewing CA, Alvarado M, Esserman LJ -
Coaching patients in the use of decision and communication aids: RE-AIM evaluation of a patient support program.
BMC health services research 2015 Belkora J, Volz S, Loth M, Teng A, Zarin-Pass M, Moore D, Esserman L -
Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.
Annals of oncology : official journal of the European Society for Medical Oncology 2015 Bossuyt V, Provenzano E, Symmans WF, Boughey JC, Coles C, Curigliano G, Dixon JM, Esserman LJ, Fastner G, Kuehn T, Peintinger F, von Minckwitz G, White J, Yang W, Badve S, Denkert C, MacGrogan G, … -
Comparison of Mammographic Findings Following Oncoplastic Mammoplasty and Lumpectomy Without Reconstruction.
Annals of surgical oncology 2015 Piper M, Peled AW, Sbitany H, Foster RD, Esserman LJ, Price ER -
Approaches to microvascular breast reconstruction after total skin-sparing mastectomy: a comparison of techniques.
Annals of plastic surgery 2015 Raghavan S, Peled AW, Hansen SL, Esserman LJ, Sbitany H -
Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy.
International journal of radiation oncology, biology, physics 2015 Fowble B, Park C, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H, Hanlon A -
Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.
International journal of radiation oncology, biology, physics 2015 Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M, TARGIT trialists' group -
The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction.
Plastic and reconstructive surgery 2015 Wang F, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H -
The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 DeMichele A, Yee D, Berry DA, Albain KS, Benz CC, Boughey J, Buxton M, Chia SK, Chien AJ, Chui SY, Clark A, Edmiston K, Elias AD, Forero-Torres A, Haddad TC, Haley B, Haluska P, Hylton NM, Isaacs C, … -
Development, implementation, and initial evaluation of a foundational open interoperability standard for oncology treatment planning and summarization.
Journal of the American Medical Informatics Association : JAMIA 2015 Warner JL, Maddux SE, Hughes KS, Krauss JC, Yu PP, Shulman LN, Mayer DK, Hogarth M, Shafarman M, Stover Fiscalini A, Esserman L, Alschuler L, Koromia GA, Gonzaga Z, Ambinder EP -
Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.
Journal of pain and symptom management 2014 Langford DJ, Schmidt B, Levine JD, Abrams G, Elboim C, Esserman L, Hamolsky D, Mastick J, Paul SM, Cooper B, Kober K, Dodd M, Dunn L, Aouizerat B, Miaskowski C -
Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014 Marks JR, Anderson KS, Engstrom P, Godwin AK, Esserman LJ, Longton G, Iversen ES, Mathew A, Patriotis C, Pepe MS -
SIS.NET: a randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer.
Cancer 2014 Wheelock AE, Bock MA, Martin EL, Hwang J, Ernest ML, Rugo HS, Esserman LJ, Melisko ME -
Expression profiling of circulating tumor cells in metastatic breast cancer.
Breast cancer research and treatment 2014 Lang JE, Scott JH, Wolf DM, Novak P, Punj V, Magbanua MJ, Zhu W, Mineyev N, Haqq CM, Crothers JR, Esserman LJ, Tripathy D, van 't Veer L, Park JW -
Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes.
Plastic and reconstructive surgery 2014 Sbitany H, Wang F, Peled AW, Lentz R, Alvarado M, Ewing CA, Esserman LJ, Fowble B, Foster RD -
Aggregate cost of mammography screening in the United States.
Annals of internal medicine 2014 Eklund M, O'Donoghue C, Esserman LJ -
Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.
Annals of surgical oncology 2014 Degnim AC, Hoskin TL, Brahmbhatt RD, Warren-Peled A, Loprinzi M, Pavey ES, Boughey JC, Hieken TJ, Jacobson S, Lemaine V, Jakub JW, Irwin C, Foster RD, Sbitany H, Saint-Cyr M, Duralde E, Ramaker S, … -
Haste makes waste, but lack of urgency is opportunity lost.
Breast cancer research and treatment 2014 Esserman L, Hayes M, Alvarado M -
Impact of total skin-sparing mastectomy incision type on reconstructive complications following radiation therapy.
Plastic and reconstructive surgery 2014 Peled AW, Foster RD, Ligh C, Esserman LJ, Fowble B, Sbitany H -
Moving beyond the breast cancer screening debate.
Journal of women's health (2002) 2014 Esserman L, O'Kane ME -
Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes.
Annals of surgical oncology 2014 Wang F, Peled AW, Garwood E, Fiscalini AS, Sbitany H, Foster RD, Alvarado M, Ewing C, Hwang ES, Esserman LJ -
Immediate implant-based breast reconstruction following total skin-sparing mastectomy in women with a history of augmentation mammaplasty: assessing the safety profile.
Plastic and reconstructive surgery 2014 Sbitany H, Wang F, Saeed L, Alvarado M, Ewing CA, Esserman LJ, Foster RD -
Imaging features of HER2 overexpression in breast cancer: a systematic review and meta-analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014 Elias SG, Adams A, Wisner DJ, Esserman LJ, van't Veer LJ, Mali WP, Gilhuijs KG, Hylton NM -
Addressing overdiagnosis and overtreatment in cancer: a prescription for change.
The Lancet. Oncology 2014 Esserman LJ, Thompson IM, Reid B, Nelson P, Ransohoff DF, Welch HG, Hwang S, Berry DA, Kinzler KW, Black WC, Bissell M, Parnes H, Srivastava S -
Fifty years of age-based screening: time for a new risk-based screening approach.
Evidence-based medicine 2014 Kerlikowske K, O'Kane ME, Esserman LJ -
Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657).
Annals of surgical oncology 2014 Cureton EL, Yau C, Alvarado MD, Krontiras H, Ollila DW, Ewing CA, Monnier S, Esserman LJ -
Oncoplastic mammoplasty as a strategy for reducing reconstructive complications associated with postmastectomy radiation therapy.
The breast journal 2014 Peled AW, Sbitany H, Foster RD, Esserman LJ -
Patient-reported outcomes and satisfaction after total skin-sparing mastectomy and immediate expander-implant reconstruction.
Annals of plastic surgery 2014 Peled AW, Duralde E, Foster RD, Fiscalini AS, Esserman LJ, Hwang ES, Sbitany H -
Accelerated approval for pertuzumab in the neoadjuvant setting: winds of change?
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Esserman LJ, DeMichele A -
Pretreatment vitamin D level and response to neoadjuvant chemotherapy in women with breast cancer on the I-SPY trial (CALGB 150007/150015/ACRIN6657).
Cancer medicine 2014 Clark AS, Chen J, Kapoor S, Friedman C, Mies C, Esserman L, DeMichele A, I-SPY1 Investigators -
Setting a research agenda for ductal carcinoma in situ that meets the current need for change.
Annals of internal medicine 2014 Esserman L, Alvarado M -
Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?
Breast cancer research and treatment 2014 Esserman LJ, Alvarado MD, Howe RJ, Mohan AJ, Harrison B, Park C, O'Donoghue C, Ozanne EM -
Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years.
Plastic and reconstructive surgery 2014 Wang F, Peled A, Foster R, Wang E, Ewing C, Alvarado M, Esserman L, Sbitany H -
Making better doctors: a survey of premedical interns working as health coaches.
Journal of cancer education : the official journal of the American Association for Cancer Education 2014 Zarin-Pass M, Belkora J, Volz S, Esserman L -
Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.
Cancer 2014 Jackson SA, Davis AA, Li J, Yi N, McCormick SR, Grant C, Fallen T, Crawford B, Loranger K, Litton J, Arun B, Vande Wydeven K, Sidani A, Farmer K, Sanders M, Hoskins K, Nussbaum R, Esserman L, Garber … -
Aggregate cost of mammography screening in the United States: comparison of current practice and advocated guidelines.
Annals of internal medicine 2014 O'Donoghue C, Eklund M, Ozanne EM, Esserman LJ -
Real-Time Measurement of Functional Tumor Volume by MRI to Assess Treatment Response in Breast Cancer Neoadjuvant Clinical Trials: Validation of the Aegis SER Software Platform.
Translational oncology 2014 Newitt DC, Aliu SO, Witcomb N, Sela G, Kornak J, Esserman L, Hylton NM -
Mammographic screening detects low-risk tumor biology breast cancers.
Breast cancer research and treatment 2014 Drukker CA, Schmidt MK, Rutgers EJ, Cardoso F, Kerlikowske K, Esserman LJ, van Leeuwen FE, Pijnappel RM, Slaets L, Bogaerts J, Van't Veer LJ -
Development of a personalized decision aid for breast cancer risk reduction and management.
BMC medical informatics and decision making 2014 Ozanne EM, Howe R, Omer Z, Esserman LJ -
Changing the terminology of cancer--reply.
JAMA 2014 Esserman LJ, Thompson IM, Reid BJ -
Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.
Journal of magnetic resonance imaging : JMRI 2013 Jafri NF, Newitt DC, Kornak J, Esserman LJ, Joe BN, Hylton NM -
Evolving paradigm for imaging, diagnosis, and management of DCIS.
Journal of the American College of Radiology : JACR 2013 Wells CJ, O'Donoghue C, Ojeda-Fournier H, Retallack HE, Esserman LJ -
Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery.
Breast cancer research and treatment 2013 Alvarado MD, Conolly J, Park C, Sakata T, Mohan AJ, Harrison BL, Hayes M, Esserman LJ, Ozanne EM -
Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.
Lancet (London, England) 2013 Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C, Eiermann W, Metaxas M, Sperk E, Sütterlin M, Brown D, Esserman L, Roncadin M, Thompson A,… -
Screening: biology dictates the fate of young women with breast cancer.
Nature reviews. Clinical oncology 2013 Eklund M, Esserman LJ -
The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.
PloS one 2013 Campbell MJ, Wolf D, Mukhtar RA, Tandon V, Yau C, Au A, Baehner F, van't Veer L, Berry D, Esserman LJ -
Impact of ductal carcinoma in situ terminology on patient treatment preferences.
JAMA internal medicine 2013 Omer ZB, Hwang ES, Esserman LJ, Howe R, Ozanne EM -
Overdiagnosis and overtreatment in cancer: an opportunity for improvement.
JAMA 2013 Esserman LJ, Thompson IM, Reid B -
Total skin-sparing mastectomy in BRCA mutation carriers.
Annals of surgical oncology 2013 Peled AW, Irwin CS, Hwang ES, Ewing CA, Alvarado M, Esserman LJ -
The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care.
Breast cancer research and treatment 2013 Elson SL, Hiatt RA, Anton-Culver H, Howell LP, Naeim A, Parker BA, Van't Veer LJ, Hogarth M, Pierce JP, Duwors RJ, Hajopoulos K, Esserman LJ, Athena Breast Health Network -
Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer.
Annals of surgical oncology 2013 Alvarado MD, Mohan AJ, Esserman LJ, Park CC, Harrison BL, Howe RJ, Thorsen C, Ozanne EM -
Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Annals of surgical oncology 2013 Mukhtar RA, Yau C, Rosen M, Tandon VJ, I-SPY 1 TRIAL and ACRIN 6657 Investigators, Hylton N, Esserman LJ -
Feasibility of Performing Total Skin-Sparing Mastectomy in Patients With Prior Circumareolar Mastopexy or Reduction Mammoplasty Incisions.
Annals of plastic surgery 2013 Vaughn CJ, Peled AW, Esserman LJ, Foster RD -
Reducing false-positive biopsies: a pilot study to reduce benign biopsy rates for BI-RADS 4A/B assessments through testing risk stratification and new thresholds for intervention.
Breast cancer research and treatment 2013 Flowers CI, O'Donoghue C, Moore D, Goss A, Kim D, Kim JH, Elias SG, Fridland J, Esserman LJ -
Recognising the benefits and harms of breast cancer screening: an opportunity to target improvement.
British journal of cancer 2013 O'Donoghue C, Esserman L -
Total skin-sparing mastectomy: a systematic review of oncologic outcomes and postoperative complications.
Annals of plastic surgery 2013 Piper M, Peled AW, Foster RD, Moore DH, Esserman LJ -
Developing safety criteria for introducing new agents into neoadjuvant trials.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 DeMichele A, Berry DA, Zujewski J, Hunsberger S, Rubinstein L, Tomaszewski JE, Kelloff G, Perlmutter J, Buxton M, Lyandres J, Albain KS, Benz C, Chien AJ, Haluska P, Leyland-Jones B, Liu MC, Munster P… -
Reply: The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy.
Plastic and reconstructive surgery 2013 Peled AW, Esserman LJ -
An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.
Breast cancer research : BCR 2013 Yau C, Sninsky J, Kwok S, Wang A, Degnim A, Ingle JN, Gillett C, Tutt A, Waldman F, Moore D, Esserman L, Benz CC -
Physician behaviors surrounding the implementation of decision and communication AIDS in a breast cancer clinic: a qualitative analysis of staff intern perceptions.
Journal of cancer education : the official journal of the American Association for Cancer Education 2012 Pass M, Volz S, Teng A, Esserman L, Belkora J -
Will early detection for breast cancer ever work?
Clinical chemistry 2012 Esserman L, Ozanne E, van't Veer L -
Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Yee D, Haddad T, Albain K, Barker A, Benz C, Boughey J, Buxton M, Chien AJ, DeMichele A, Dilts D, Elias A, Haluska P, Hogarth M, Hu A, Hytlon N, Kaplan HG, Kelloff GG, Khan Q, Lang J, Leyland-Jones B,… -
Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Khatcheressian JL, Hurley P, Bantug E, Esserman LJ, Grunfeld E, Halberg F, Hantel A, Henry NL, Muss HB, Smith TJ, Vogel VG, Wolff AC, Somerfield MR, Davidson NE, American Society of Clinical Oncology -
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Wulfkuhle JD, Berg D, Wolff C, Langer R, Tran K, Illi J, Espina V, Pierobon M, Deng J, DeMichele A, Walch A, Bronger H, Becker I, Waldhör C, Höfler H, Esserman L, I-SPY 1 TRIAL Investigators, Liotta … -
Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.
Breast cancer research and treatment 2012 Lips EH, Mukhtar RA, Yau C, de Ronde JJ, Livasy C, Carey LA, Loo CE, Vrancken-Peeters MJ, Sonke GS, Berry DA, Van't Veer LJ, Esserman LJ, Wesseling J, Rodenhuis S, Shelley Hwang E, I-SPY TRIAL … -
Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors.
Breast cancer research and treatment 2012 Petrillo LA, Wolf DM, Kapoun AM, Wang NJ, Barczak A, Xiao Y, Korkaya H, Baehner F, Lewicki J, Wicha M, Park JW, Spellman PT, Gray JW, Van't Veer L, Esserman LJ -
Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure.
Plastic and reconstructive surgery 2012 Peled AW, Foster RD, Esserman LJ, Park CC, Hwang ES, Fowble B -
Breast cancer screening: the questions answered.
Nature reviews. Clinical oncology 2012 Autier P, Esserman LJ, Flowers CI, Houssami N -
The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors.
Breast cancer research and treatment 2012 Bock M, Moore D, Hwang J, Shumay D, Lawson L, Hamolsky D, Esserman L, Rugo H, Chien AJ, Park J, Munster P, Melisko M -
Adoption, acceptability, and accuracy of an online clinical trial matching website for breast cancer.
Journal of medical Internet research 2012 Cohen E, Belkora J, Tyler J, Schreiner J, Deering MJ, Grama L, Duggan B, Illi J, Pederson J, Anand A, Teng A, McCreary E, Moore D, Tripathy D, Hogarth M, Lieberman M, Park J, Esserman L -
Biology of breast cancer in Nigerian women: a pilot study.
Annals of African medicine 2012 Adisa CA, Eleweke N, Alfred AA, Campbell MJ, Sharma R, Nseyo O, Tandon V, Mukhtar R, Greninger A, Risi JD, Esserman LJ -
Whole-genome analysis informs breast cancer response to aromatase inhibition.
Nature 2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, Weber J, Chen K, Koboldt DC, Kandoth C, Schierding WS,… -
A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.
The Lancet. Oncology 2012 Fumagalli D, Bedard PL, Nahleh Z, Michiels S, Sotiriou C, Loi S, Sparano JA, Ellis M, Hylton N, Zujewski JA, Hudis C, Esserman L, Piccart M, BIG-NABCG collaboration -
Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.
Annals of surgery 2012 Chang EI, Peled AW, Foster RD, Lin C, Zeidler KR, Ewing CA, Alvarado M, Hwang ES, Esserman LJ -
Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL.
Radiology 2012 Hylton NM, Blume JD, Bernreuter WK, Pisano ED, Rosen MA, Morris EA, Weatherall PT, Lehman CD, Newstead GM, Polin S, Marques HS, Esserman LJ, Schnall MD, ACRIN 6657 Trial Team and I-SPY 1 TRIAL … -
The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study.
Plastic and reconstructive surgery 2012 Peled AW, Foster RD, Garwood ER, Moore DH, Ewing CA, Alvarado M, Hwang ES, Esserman LJ -
Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Esserman LJ, Berry DA, DeMichele A, Carey L, Davis SE, Buxton M, Hudis C, Gray JW, Perou C, Yau C, Livasy C, Krontiras H, Montgomery L, Tripathy D, Lehman C, Liu MC, Olopade OI, Rugo HS, Carpenter JT,… -
Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.
Annals of surgical oncology 2012 Mukhtar RA, Moore AP, Tandon VJ, Nseyo O, Twomey P, Adisa CA, Eleweke N, Au A, Baehner FL, Moore DH, McGrath MS, Olopade OI, Gray JW, Campbell MJ, Esserman LJ -
Breast cancer recurrence is dictated by high-risk biology, not choice of surgery.
Oncology (Williston Park, N.Y.) 2012 Esserman LJ -
Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts.
Annals of surgical oncology 2012 Warren Peled A, Foster RD, Stover AC, Itakura K, Ewing CA, Alvarado M, Hwang ES, Esserman LJ -
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.
The Journal of experimental medicine 2012 Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A -
Overdiagnosis and overtreatment of breast cancer.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2012 Alvarado M, Ozanne E, Esserman L -
Targeting Molecular Aberrations in Breast Cancer: Is It about Time?
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2012 Esserman L, Benz C, Demichele A -
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Breast cancer research and treatment 2011 Esserman LJ, Berry DA, Cheang MC, Yau C, Perou CM, Carey L, DeMichele A, Gray JW, Conway-Dorsey K, Lenburg ME, Buxton MB, Davis SE, van't Veer LJ, Hudis C, Chin K, Wolf D, Krontiras H, Montgomery L, … -
Accelerating identification and regulatory approval of investigational cancer drugs.
JAMA 2011 Esserman LJ, Woodcock J -
Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types.
The Lancet. Oncology 2011 Loi S, Symmans WF, Bartlett JM, Fumagalli D, Van't Veer L, Forbes JF, Bedard P, Denkert C, Zujewski J, Viale G, Pusztai L, Esserman LJ, Leyland-Jones BR -
Impact of mammographic screening on the detection of good and poor prognosis breast cancers.
Breast cancer research and treatment 2011 Esserman LJ, Shieh Y, Rutgers EJ, Knauer M, Retèl VP, Mook S, Glas AM, Moore DH, Linn S, van Leeuwen FE, van 't Veer LJ -
Outcome of long term active surveillance for estrogen receptor-positive ductal carcinoma in situ.
Breast (Edinburgh, Scotland) 2011 Meyerson AF, Lessing JN, Itakura K, Hylton NM, Wolverton DE, Joe BN, Esserman LJ, Hwang ES -
Leukocyte composition of human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011 Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, Coussens LM -
Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN 6657, InterSPORE Trial).
Breast cancer research and treatment 2011 Lin C, Buxton MB, Moore D, Krontiras H, Carey L, DeMichele A, Montgomery L, Tripathy D, Lehman C, Liu M, Olapade O, Yau C, Berry D, Esserman LJ, I-SPY TRIAL Investigators -
Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.
Breast cancer research and treatment 2011 Mukhtar RA, Moore AP, Nseyo O, Baehner FL, Au A, Moore DH, Twomey P, Campbell MJ, Esserman LJ -
Biologic markers determine both the risk and the timing of recurrence in breast cancer.
Breast cancer research and treatment 2011 Esserman LJ, Moore DH, Tsing PJ, Chu PW, Yau C, Ozanne E, Chung RE, Tandon VJ, Park JW, Baehner FL, Kreps S, Tutt AN, Gillett CE, Benz CC -
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
JAMA 2011 Hatzis C, Pusztai L, Valero V, Booser DJ, Esserman L, Lluch A, Vidaurre T, Holmes F, Souchon E, Wang H, Martin M, Cotrina J, Gomez H, Hubbard R, Chacón JI, Ferrer-Lozano J, Dyer R, Buxton M, Gong Y, … -
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Ellis MJ, Suman VJ, Hoog J, Lin L, Snider J, Prat A, Parker JS, Luo J, DeSchryver K, Allred DC, Esserman LJ, Unzeitig GW, Margenthaler J, Babiera GV, Marcom PK, Guenther JM, Watson MA, Leitch M, Hunt … -
Characterizing the impact of 25 years of DCIS treatment.
Breast cancer research and treatment 2011 Ozanne EM, Shieh Y, Barnes J, Bouzan C, Hwang ES, Esserman LJ -
The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ.
Clinical breast cancer 2011 Itakura K, Lessing J, Sakata T, Heinzerling A, Vriens E, Wisner D, Alvarado M, Esserman L, Ewing C, Hylton N, Hwang ES -
Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.
Expert review of molecular diagnostics 2011 Mukhtar RA, Nseyo O, Campbell MJ, Esserman LJ -
A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Breast cancer research : BCR 2010 Yau C, Esserman L, Moore DH, Waldman F, Sninsky J, Benz CC -
The Communication and Care Plan: a novel approach to patient-centered clinical information systems.
Journal of biomedical informatics 2010 Hogarth M, Hajopoulos K, Young M, Cowles N, Churin J, Hornthal B, Esserman L -
Long-term prognostic role of functional limitations among women with breast cancer.
Journal of the National Cancer Institute 2010 Braithwaite D, Satariano WA, Sternfeld B, Hiatt RA, Ganz PA, Kerlikowske K, Moore DH, Slattery ML, Tammemagi M, Castillo A, Melisko M, Esserman L, Weltzien EK, Caan BJ -
Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.
Breast cancer research and treatment 2010 Campbell MJ, Tonlaar NY, Garwood ER, Huo D, Moore DH, Khramtsov AI, Au A, Baehner F, Chen Y, Malaka DO, Lin A, Adeyanju OO, Li S, Gong C, McGrath M, Olopade OI, Esserman LJ -
Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience.
Cancer 2010 Liu LC, Lang JE, Lu Y, Roe D, Hwang SE, Ewing CA, Esserman LJ, Morita E, Treseler P, Leong SP -
Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction.
Archives of surgery (Chicago, Ill. : 1960) 2010 Warren Peled A, Itakura K, Foster RD, Hamolsky D, Tanaka J, Ewing C, Alvarado M, Esserman LJ, Hwang ES -
Lessons learned from genetic testing.
JAMA 2010 Esserman L, Kaklamani V -
Expanding the reach of decision and communication aids in a breast care center: a quality improvement study.
Patient education and counseling 2010 Belkora JK, Teng A, Volz S, Loth MK, Esserman LJ -
Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.
Lancet (London, England) 2010 Vaidya JS, Joseph DJ, Tobias JS, Bulsara M, Wenz F, Saunders C, Alvarado M, Flyger HL, Massarut S, Eiermann W, Keshtgar M, Dewar J, Kraus-Tiefenbacher U, Sütterlin M, Esserman L, Holtveg HM, Roncadin … -
Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins?
International journal of radiation oncology, biology, physics 2010 Chan LW, Rabban J, Hwang ES, Bevan A, Alvarado M, Ewing C, Esserman L, Fowble B -
Solving the overdiagnosis dilemma.
Journal of the National Cancer Institute 2010 Esserman L, Thompson I -
Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.
Breast cancer research and treatment 2010 Garwood ER, Kumar AS, Baehner FL, Moore DH, Au A, Hylton N, Flowers CI, Garber J, Lesnikoski BA, Hwang ES, Olopade O, Port ER, Campbell M, Esserman LJ -
Application of screening principles to the reconstructed breast.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Zakhireh J, Fowble B, Esserman LJ -
Rethinking screening for breast cancer and prostate cancer.
JAMA 2009 Esserman L, Shieh Y, Thompson I -
Bacteriologic features of surgical site infections following breast surgery.
American journal of surgery 2009 Mukhtar RA, Throckmorton AD, Alvarado MD, Ewing CA, Esserman LJ, Chiu C, Hwang ES -
Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.
BMC cancer 2009 Chen YY, DeVries S, Anderson J, Lessing J, Swain R, Chin K, Shim V, Esserman LJ, Waldman FM, Hwang ES -
A comparison of RNA amplification techniques at sub-nanogram input concentration.
BMC genomics 2009 Lang JE, Magbanua MJ, Scott JH, Makrigiorgos GM, Wang G, Federman S, Esserman LJ, Park JW, Haqq CM -
I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.
Clinical pharmacology and therapeutics 2009 Barker AD, Sigman CC, Kelloff GJ, Hylton NM, Berry DA, Esserman LJ -
Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.
Journal of the American College of Surgeons 2009 Olson JA, Budd GT, Carey LA, Harris LA, Esserman LJ, Fleming GF, Marcom PK, Leight GS, Giuntoli T, Commean P, Bae K, Luo J, Ellis MJ -
Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.
The breast journal 2009 Lang JE, Liu LC, Lu Y, Jenkins T, Hwang SE, Esserman LJ, Ewing CA, Alvarado M, Morita E, Treseler P, Leong SP -
Oncologist use of the Adjuvant! model for risk communication: a pilot study examining patient knowledge of 10-year prognosis.
BMC cancer 2009 Belkora JK, Rugo HS, Moore DH, Hutton DW, Chen DF, Esserman LJ -
The UCSC Cancer Genomics Browser.
Nature methods 2009 Zhu J, Sanborn JZ, Benz S, Szeto C, Hsu F, Kuhn RM, Karolchik D, Archie J, Lenburg ME, Esserman LJ, Kent WJ, Haussler D, Wang T -
Hypertension is an independent predictor of survival disparity between African-American and white breast cancer patients.
International journal of cancer 2009 Braithwaite D, Tammemagi CM, Moore DH, Ozanne EM, Hiatt RA, Belkora J, West DW, Satariano WA, Liebman M, Esserman L -
Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients.
Annals of surgery 2009 Garwood ER, Moore D, Ewing C, Hwang ES, Alvarado M, Foster RD, Esserman LJ -
When informed, all women do not prefer breast conservation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Throckmorton AD, Esserman LJ -
Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Ozanne EM, Braithwaite D, Sepucha K, Moore D, Esserman L, Belkora J -
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.
BMC cancer 2008 Tutt A, Wang A, Rowland C, Gillett C, Lau K, Chew K, Dai H, Kwok S, Ryder K, Shu H, Springall R, Cane P, McCallie B, Kam-Morgan L, Anderson S, Buerger H, Gray J, Bennington J, Esserman L, Hastie T, … -
Converting evidence to practice: a guide for the clinical application of MRI for the screening and management of breast cancer.
European journal of cancer (Oxford, England : 1990) 2008 Zakhireh J, Gomez R, Esserman L -
Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer?
Journal of the American College of Surgeons 2008 Liu LC, Lang JE, Jenkins T, Lu Y, Ewing CA, Hwang SE, Sokol S, Alvarado M, Esserman LJ, Morita E, Treseler P, Leong SP -
Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center.
Patient education and counseling 2008 Belkora JK, Loth MK, Chen DF, Chen JY, Volz S, Esserman LJ -
Invasive breast cancer: predicting disease recurrence by using high-spatial-resolution signal enhancement ratio imaging.
Radiology 2008 Li KL, Partridge SC, Joe BN, Gibbs JE, Lu Y, Esserman LJ, Hylton NM -
Risk communication with patients with breast cancer: cautionary notes about printing Adjuvant! estimates.
The Lancet. Oncology 2008 Belkora J, Rugo HS, Moore DH, Hutton D, Esserman L -
Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 Kumar AS, Benz CC, Shim V, Minami CA, Moore DH, Esserman LJ -
Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Buchholz TA, Lehman CD, Harris JR, Pockaj BA, Khouri N, Hylton NF, Miller MJ, Whelan T, Pierce LJ, Esserman LJ, Newman LA, Smith BL, Bear HD, Mamounas EP -
Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.
Journal of proteome research 2008 Wulfkuhle JD, Speer R, Pierobon M, Laird J, Espina V, Deng J, Mammano E, Yang SX, Swain SM, Nitti D, Esserman LJ, Belluco C, Liotta LA, Petricoin EF -
Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning.
Implementation science : IS 2008 Belkora J, Edlow B, Aviv C, Sepucha K, Esserman L -
Optimizing the total skin-sparing mastectomy.
Archives of surgery (Chicago, Ill. : 1960) 2008 Wijayanayagam A, Kumar AS, Foster RD, Esserman LJ -
A role for biomarkers in the screening and diagnosis of breast cancer in younger women.
Expert review of molecular diagnostics 2007 Esserman LJ, Shieh Y, Park JW, Ozanne EM -
Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Park JW, Melisko ME, Esserman LJ, Jones LA, Wollan JB, Sims R -
Fluorescence in situ hybridization of ductal lavage samples identifies malignant phenotypes from cytologically normal cells in women with breast cancer.
Cancer 2007 Adduci KM, Annis CE, DeVries S, Chew KL, Boutin J, Magrane G, Ljung BM, Waldman FM, Esserman LJ -
Pilot trial of a computerized decision aid for breast cancer prevention.
The breast journal 2007 Ozanne EM, Annis C, Adduci K, Showstack J, Esserman L -
Ductal carcinoma in situ in BRCA mutation carriers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Hwang ES, McLennan JL, Moore DH, Crawford BB, Esserman LJ, Ziegler JL -
Analysis of molecular inversion probe performance for allele copy number determination.
Genome biology 2007 Wang Y, Moorhead M, Karlin-Neumann G, Wang NJ, Ireland J, Lin S, Chen C, Heiser LM, Chin K, Esserman L, Gray JW, Spellman PT, Faham M -
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.
Cancer cell 2006 Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, Chen F, Feiler H, Tokuyasu T, Kingsley C, Dairkee S, Meng Z, Chew K, Pinkel D, Jain A, Ljung BM, … -
Type and duration of exogenous hormone use affects breast cancer histology.
Annals of surgical oncology 2006 Kumar AS, Cureton E, Shim V, Sakata T, Moore DH, Benz CC, Esserman LJ, Hwang ES -
Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ.
American journal of surgery 2006 Kumar AS, Chen DF, Au A, Chen YY, Leung J, Garwood ER, Gibbs J, Hylton N, Esserman LJ -
Magnetic resonance imaging captures the biology of ductal carcinoma in situ.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006 Esserman LJ, Kumar AS, Herrera AF, Leung J, Au A, Chen YY, Moore DH, Chen DF, Hellawell J, Wolverton D, Hwang ES, Hylton NM -
Breast cancer growth prevention by statins.
Cancer research 2006 Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, Baehner F, Kumar AS, Adduci K, Marx C, Petricoin EF, Liotta LA, Winters M, Benz S, Benz CC -
Evaluation of a visit preparation intervention implemented in two rural, underserved counties of Northern California.
Patient education and counseling 2006 Belkora J, Katapodi M, Moore D, Franklin L, Hopper K, Esserman L -
Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice.
Cancer gene therapy 2006 Jabrane-Ferrat N, Campbell MJ, Esserman LJ, Peterlin BM -
Clinical trials are required to prove the chemopreventive worth of statins.
Archives of internal medicine 2006 Kumar AS, Benz CC, Esserman LJ -
A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006 Kumar AS, Campbell M, Benz CC, Esserman LJ -
Mammographic, sonographic, and pathologic characteristics of Burkitt's lymphoma in a patient referred for diagnostic mammography.
AJR. American journal of roentgenology 2006 Esserman L, Sexton R, Yu QQ, Cabello-Inchausti B -
Breast cancer risk assessment and prevention: a framework for shared decision-making consultations.
The breast journal 2006 Ozanne EM, Klemp JR, Esserman LJ -
Genetic/familial high-risk assessment: breast and ovarian.
Journal of the National Comprehensive Cancer Network : JNCCN 2006 Daly MB, Axilbund JE, Bryant E, Buys S, Eng C, Friedman S, Esserman LJ, Farrell CD, Ford JM, Garber JE, Jeter JM, Kohlmann W, Lynch PM, Marcom PK, Nabell LM, Offit K, Osarogiagbon RU, Pasche B, Reiser… -
Statins: health-promoting agents show promise for breast cancer prevention.
Clinical breast cancer 2005 Kumar AS, Esserman LJ -
Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.
Breast cancer research : BCR 2005 Esserman LJ, Ozanne EM, Dowsett M, Slingerland JM -
Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.
JAMA 2005 Nanda R, Schumm LP, Cummings S, Fackenthal JD, Sveen L, Ademuyiwa F, Cobleigh M, Esserman L, Lindor NM, Neuhausen SL, Olopade OI -
Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.
The breast journal 2005 Tan YY, Wu CT, Fan YG, Hwang S, Ewing C, Lane K, Esserman L, Lu Y, Treseler P, Morita E, Leong SP -
The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer.
Annals of surgical oncology 2005 Fan YG, Tan YY, Wu CT, Treseler P, Lu Y, Chan CW, Hwang S, Ewing C, Esserman L, Morita E, Leong SP -
Ratio of positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients.
The breast journal 2005 Tan YY, Fan YG, Lu Y, Hwang S, Ewing C, Esserman L, Morita E, Treseler P, Leong SP -
MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.
AJR. American journal of roentgenology 2005 Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Tripathy D, Wolverton DS, Rugo HS, Hwang ES, Ewing CA, Hylton NM -
Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Petricoin EF, Bichsel VE, Calvert VS, Espina V, Winters M, Young L, Belluco C, Trock BJ, Lippman M, Fishman DA, Sgroi DC, Munson PJ, Esserman LJ, Liotta LA -
Immune dysfunction and micrometastases in women with breast cancer.
Breast cancer research and treatment 2005 Campbell MJ, Scott J, Maecker HT, Park JW, Esserman LJ -
Integration of imaging in the management of breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Esserman L -
Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans.
Breast cancer research and treatment 2005 Misell LM, Hwang ES, Au A, Esserman L, Hellerstein MK -
Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease.
Archives of surgery (Chicago, Ill. : 1960) 2005 Foster RD, Hansen SL, Esserman LJ, Hwang ES, Ewing C, Lane K, Anthony JP -
Internal mammary sentinel lymph node mapping for invasive breast cancer: implications for staging and treatment.
The breast journal 2005 Park C, Seid P, Morita E, Iwanaga K, Weinberg V, Quivey J, Hwang ES, Esserman LJ, Leong SP -
Recruitment, genetic counseling, and BRCA testing for underserved women at a public hospital.
Genetic testing 2005 Lee R, Beattie M, Crawford B, Mak J, Stewart N, Komaromy M, Esserman L, Shaw L, McLennan J, Strachowski L, Luce J, Ziegler J -
Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation.
Journal of the American College of Surgeons 2004 Lang JE, Esserman LJ, Ewing CA, Rugo HS, Lane KT, Leong SP, Hwang ES -
Evaluation of breast cancer risk assessment techniques: a cost-effectiveness analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004 Ozanne EM, Esserman LJ -
Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.
Cancer 2004 Hwang ES, Nyante SJ, Yi Chen Y, Moore D, DeVries S, Korkola JE, Esserman LJ, Waldman FM -
Applying the neoadjuvant paradigm to ductal carcinoma in situ.
Annals of surgical oncology 2004 Esserman L, Sepucha K, Ozanne E, Hwang ES -
Neoadjuvant chemotherapy for primary breast cancer: lessons learned and opportunities to optimize therapy.
Annals of surgical oncology 2004 Esserman L -
Neoadjuvant hormonal therapy for ductal carcinoma in situ: trial design and preliminary results.
Annals of surgical oncology 2004 Hwang ES, Esserman L -
An XML message broker framework for exchange and integration of microarray data.
Bioinformatics (Oxford, England) 2003 Tjandra D, Wong S, Shen W, Pulliam B, Yu E, Esserman L -
Racial differences in mammographic breast density.
Cancer 2003 del Carmen MG, Hughes KS, Halpern E, Rafferty E, Kopans D, Parisky YR, Sardi A, Esserman L, Rust S, Michaelson J -
Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium.
Cancer research 2003 Shim V, Gauthier ML, Sudilovsky D, Mantei K, Chew KL, Moore DH, Cha I, Tlsty TD, Esserman LJ -
Magnetic resonance imaging in patients diagnosed with ductal carcinoma-in-situ: value in the diagnosis of residual disease, occult invasion, and multicentricity.
Annals of surgical oncology 2003 Hwang ES, Kinkel K, Esserman LJ, Lu Y, Weidner N, Hylton NM -
MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?
International immunology 2003 Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman L, Peterlin BM -
Failure to harvest sentinel lymph nodes identified by preoperative lymphoscintigraphy in breast cancer patients.
The breast journal 2003 Wu CT, Morita ET, Treseler PA, Esserman LJ, Hwang ES, Kuerer HM, Santos CL, Leong SP -
Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions.
AJR. American journal of roentgenology 2003 Parisky YR, Sardi A, Hamm R, Hughes K, Esserman L, Rust S, Callahan K -
Improving the quality of decision making in breast cancer: consultation planning template and consultation recording template.
Oncology nursing forum 2003 Sepucha KR, Belkora JK, Aviv C, Mutchnik S, Esserman LJ -
Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy.
AJR. American journal of roentgenology 2002 Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Sudilovsky D, Hylton NM -
Axillary metastasis from a malignant mullerian mixed tumor.
The breast journal 2002 Cura MA, Blanco M, Esserman L -
Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers.
Molecular and cellular biology 2002 Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman LJ, Peterlin BM -
Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.
Journal of the National Cancer Institute 2002 Euhus DM, Smith KC, Robinson L, Stucky A, Olopade OI, Cummings S, Garber JE, Chittenden A, Mills GB, Rieger P, Esserman L, Crawford B, Hughes KS, Roche CA, Ganz PA, Seldon J, Fabian CJ, Klemp J, … -
Consultation planning to help breast cancer patients prepare for medical consultations: effect on communication and satisfaction for patients and physicians.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002 Sepucha KR, Belkora JK, Mutchnick S, Esserman LJ -
Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.
In vitro cellular & developmental biology. Animal 2002 Campbell MJ, Wollish WS, Lobo M, Esserman LJ -
Magnetic resonance imaging for primary breast cancer management: current role and new applications.
Endocrine-related cancer 2002 Esserman L, Wolverton D, Hylton N -
Skin-sparing mastectomy and immediate breast reconstruction: a prospective cohort study for the treatment of advanced stages of breast carcinoma.
Annals of surgical oncology 2002 Foster RD, Esserman LJ, Anthony JP, Hwang ES, Do H -
New approaches to the imaging, diagnosis, and biopsy of breast lesions.
Cancer journal (Sudbury, Mass.) 2002 Esserman LJ -
Improving the accuracy of mammography: volume and outcome relationships.
Journal of the National Cancer Institute 2002 Esserman L, Cowley H, Eberle C, Kirkpatrick A, Chang S, Berbaum K, Gale A -
Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.
Journal of the National Cancer Institute 2001 Dooley WC, Ljung BM, Veronesi U, Cazzaniga M, Elledge RM, O'Shaughnessy JA, Kuerer HM, Hung DT, Khan SA, Phillips RF, Ganz PA, Euhus DM, Esserman LJ, Haffty BG, King BL, Kelley MC, Anderson MM, Schmit… -
Does timely assessment affect the anxiety associated with an abnormal mammogram result?
Journal of women's health & gender-based medicine 2001 Haas J, Kaplan C, McMillan A, Esserman LJ -
MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer.
Annals of surgical oncology 2001 Esserman L, Kaplan E, Partridge S, Tripathy D, Rugo H, Park J, Hwang S, Kuerer H, Sudilovsky D, Lu Y, Hylton N -
The impact of alternative practices on the cost and quality of mammographic screening in the United States.
Clinical breast cancer 2001 Burnside E, Belkora J, Esserman L -
Ductal growth is impeded in mammary glands of C-neu transgenic mice.
Oncogene 2000 Mukherjee S, Louie SG, Campbell M, Esserman L, Shyamala G -
MR imaging of the breast in patients with positive margins after lumpectomy: influence of the time interval between lumpectomy and MR imaging.
AJR. American journal of roentgenology 2000 Frei KA, Kinkel K, Bonel HM, Lu Y, Esserman LJ, Hylton NM -
Integration of breast imaging into cancer management.
Current oncology reports 2000 Esserman LJ, Wolverton D, Hylton N -
Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability.
AJR. American journal of roentgenology 2000 Kinkel K, Helbich TH, Esserman LJ, Barclay J, Schwerin EH, Sickles EA, Hylton NM -
Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.
Annals of surgical oncology 2000 Kuerer HM, Hwang ES, Anthony JP, Dudley RA, Crawford B, Aubry WM, Esserman LJ -
Building bridges between physicians and patients: results of a pilot study examining new tools for collaborative decision making in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000 Sepucha KR, Belkora JK, Tripathy D, Esserman LJ -
Management of ductal carcinoma in situ.
The Surgical clinics of North America 1999 Hwang ES, Esserman LJ -
Biological therapies for breast carcinoma: concepts for improvement in survival.
Seminars in oncology 1999 Borden EC, Esserman L, Linder DJ, Campbell MJ, Fulton AM -
Prophylactic mastectomy in women with a high risk of breast cancer.
The New England journal of medicine 1999 Kuerer HM, Hwang ES, Esserman LJ -
Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.
Cancer immunology, immunotherapy : CII 1999 Esserman LJ, Lopez T, Montes R, Bald LN, Fendly BM, Campbell MJ -
Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor Histopathology and Angiogenesis in Breast Carcinoma.
The breast journal 1999 Esserman L, Hylton N, George T, Weidner N -
Utility of magnetic resonance imaging in the management of breast cancer: evidence for improved preoperative staging.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999 Esserman L, Hylton N, Yassa L, Barclay J, Frankel S, Sickles E -
A multicenter randomized trial of DIAC for cyclical mastopathy.
Primary care update for Ob/Gyns 1998 Ballagh SA, Stover TL, Maragos TG, Reynolds MD, Wolfley GD, Esserman LJ, Herbst JR, Kirkegaard LW, Teichman SL -
Is routine frozen section assessment feasible in the practice environment of the 1990s?
The cancer journal from Scientific American 1997 Esserman L, Weidner N -
Hormone replacement therapy and breast cancer risk.
Cancer practice 1997 Burke CC, Gullatte MM, Vigliani M, Ruggiero RJ, Esserman L, Crawford B -
Ultrasound tissue characterization of breast biopsy specimens: expanded study.
Ultrasonic imaging 1996 Mortensen CL, Edmonds PD, Gorfu Y, Hill JR, Jensen JF, Schattner P, Shifrin LA, Valdes AD, Jeffrey SS, Esserman LJ -
Barriers to care and treatment: the challenge of daily radiation therapy.
Cancer practice 1996 Igoe S, Collins C, Hamolsky D, Esserman LJ -
Should we recommend screening mammography for women aged 40 to 49?
Oncology (Williston Park, N.Y.) 1996 Esserman L, Kerlikowske K -
Breast.
Pathology (Philadelphia, Pa.) 1996 Weidner N, Esserman LJ -
Trade-offs between survival and breast preservation for three initial treatments of ductal carcinoma-in-situ of the breast.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996 Hillner BE, Desch CE, Carlson RW, Smith TJ, Esserman L, Bear HD -
Potentially ineffective care. A new outcome to assess the limits of critical care.
JAMA 1995 Esserman L, Belkora J, Lenert L -
Cost per anomaly: what does a diaphragmatic hernia cost?
Journal of pediatric surgery 1995 Metkus AP, Esserman L, Sola A, Harrison MR, Adzick NS -
An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site.
Blood 1991 Takahashi S, Esserman L, Levy R -
Follicular lymphoma: a model of lymphoid tumor progression in man.
Annals of oncology : official journal of the European Society for Medical Oncology 1991 Zelenetz AD, Campbell MJ, Bahler DW, Takahashi S, Oren R, Esserman L, Umetsu DT, Kwak LW, Maloney DG, Brown S -
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 1990 Campbell MJ, Esserman L, Byars NE, Allison AC, Levy R -
Development of a new therapeutic approach to B cell malignancy. The induction of immunity by the host against cell surface receptor on the tumor.
International reviews of immunology 1989 Campbell MJ, Esserman L, Byars NE, Allison AC, Levy R -
Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide.
Journal of immunology (Baltimore, Md. : 1950) 1988 Campbell MJ, Esserman L, Levy R -
Myocardial performance and extracellular ionized calcium in a severely failing human heart.
Annals of internal medicine 1983 Ginsburg R, Esserman LJ, Bristow MR -
A novel method for emergency immobilization of the wrist during cross-country skiing.
The American journal of sports medicine 1980 Goldman MP, Esserman LJ, Bausback KN, Camargo CA, Nagel DA