Kuan Zhang, PhD
Associate Specialist
Cardiovascular Research Inst
School of Medicine

Publications (13)

Top publication keywords:
Focal AdhesionsMitochondrial MembranesEndothelial CellsMyofibroblastsLungMechanistic Target of Rapamycin Complex 1Pulmonary AlveoliCystsGTP PhosphohydrolasesAlveolar Epithelial CellsCytoskeletonWnt ProteinsReceptor Tyrosine Kinase-like Orphan ReceptorsMetalloendopeptidasesWnt-5a Protein

• Lung patterning: Is a distal-to-proximal gradient of cell allocation and fate decision a general paradigm?: A gradient of distal-to-proximal distribution and differentiation of tip progenitors produces distinct compartments in the lung.
  BioEssays : news and reviews in molecular, cellular and developmental biology 2023 Zhang K, Aung T, Yao E, Chuang PT
• mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity.
  Nature communications 2022 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT
• Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions.
  PLoS biology 2022 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Volk RF, Hofmann KL, Zaro B, Chuang PT
• A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange.
  Developmental cell 2022 Zhang K, Yao E, Wang SA, Chuang E, Wong J, Minichiello L, Schroeder A, Eckalbar W, Wolters PJ, Chuang PT
• Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria.
  eLife 2022 Zhang K, Yao E, Chen B, Chuang E, Wong J, Seed RI, Nishimura SL, Wolters PJ, Chuang PT

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• A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis.
  eLife 2020 Zhang K, Yao E, Lin C, Chou YT, Wong J, Li J, Wolters PJ, Chuang PT
• Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact.
  Cell death and differentiation 2019 Tang J, Zhang K, Dong J, Yan C, Hu C, Ji H, Chen L, Chen S, Zhao H, Song Z
• Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury.
  Stem cells (Dayton, Ohio) 2017 Yao E, Lin C, Wu Q, Zhang K, Song H, Chuang PT
• YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
  eLife 2017 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT
• Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma.
  The Journal of biological chemistry 2017 Song H, Lin C, Yao E, Zhang K, Li X, Wu Q, Chuang PT
• Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
  Cell death and differentiation 2015 Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z
• Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage.
  EMBO reports 2014 Zhang K, Li H, Song Z
• Loss of Yme1L perturbates mitochondrial dynamics.
  Cell death & disease 2013 Ruan Y, Li H, Zhang K, Jian F, Tang J, Song Z