Kristen Berendzen, MD, PhD
Assistant Professor
Psychiatry
School of Medicine

Education & Training

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• Residency Psychiatry University of California, San Francisco 06/2019
• M.D. Medicine University of California, San Diego 06/2015
• Ph.D. Neuroscience University of California, San Diego 06/2013
• BS Neuroscience Vanderbilt University 06/2004

Websites

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• Berendzen Lab (berendzenlab.ucsf.edu)

Publications (20)

Top publication keywords:
GrasslandUnfolded Protein ResponseSocial BehaviorSexual Behavior, AnimalPair BondNeurobiologyArvicolinaePyruvate Dehydrogenase ComplexDichloroacetic AcidCaenorhabditis elegansHealthy AgingCaenorhabditis elegans ProteinsHomeostasisPyruvate Dehydrogenase Complex Deficiency DiseaseReceptors, Oxytocin

• Dimorphic substrates, monomorphic outcomes: Social behavior neural circuit tuning in social monogamy.
  Progress in neurobiology 2026 Shvareva VA, Berendzen KM, Bender KJ, Manoli DS
• Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding.
  Cell genomics 2026 Abuelanin M, Kaya G, Lake JA, Lambert C, Wu MV, Berendzen KM, Wood J, Krasheninnikova K, Solomon NG, Donaldson ZR, Bales KL, Howe K, Korlach J, Manoli D, Tollkuhn J, Dennis MY
• Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding.
  bioRxiv : the preprint server for biology 2026 Abuelanin M, Kaya G, Lake JA, Lambert C, Wu MV, Berendzen KM, Krasheninnikova K, Wood JMD, Solomon NG, Donaldson ZR, Bales KL, Howe K, Korlach J, Manoli D, Tollkuhn J, Dennis MY
• Oxytocin receptor controls promiscuity and development in prairie voles.
  bioRxiv : the preprint server for biology 2024 Sharma R, Berendzen KM, Everitt A, Wang B, Williams G, Wang S, Quine K, Larios RD, Long KLP, Hoglen N, Sulaman BA, Heath MC, Sherman M, Klinkel R, Cai A, Galo D, Caamal LC, Goodwin NL, Beery A, Bales …
• The germline coordinates mitokine signaling.
  Cell 2024 Shen K, Durieux J, Mena CG, Webster BM, Tsui CK, Zhang H, Joe L, Berendzen KM, Dillin A

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• Understanding social attachment as a window into the neural basis of prosocial behavior.
  Frontiers in neurology 2023 Berendzen KM
• The germline coordinates mitokine signaling.
  bioRxiv : the preprint server for biology 2023 Shen K, Durieux J, Mena CG, Webster BM, Kimberly Tsui C, Zhang H, Joe L, Berendzen K, Dillin A
• Attachment across the lifespan: Examining the intersection of pair bonding neurobiology and healthy aging.
  Neuroscience and biobehavioral reviews 2023 Berendzen KM, Bales KL, Manoli DS
• Oxytocin receptor is not required for social attachment in prairie voles.
  Neuron 2023 Berendzen KM, Sharma R, Mandujano MA, Wei Y, Rogers FD, Simmons TC, Seelke AMH, Bond JM, Larios R, Goodwin NL, Sherman M, Parthasarthy S, Espineda I, Knoedler JR, Beery A, Bales KL, Shah NM, Manoli DS
• Rethinking the Architecture of Attachment: New Insights into the Role for Oxytocin Signaling.
  Affective science 2022 Berendzen KM, Manoli DS
• Genetic Loss of Oxytocin Receptor Signaling Sex-Specifically Affects the Dynamics of Pair Bond Formation and Promiscuity in Prairie Voles.
  Biological Psychiatry 2021 Kristen Berendzen, Ruchira Sharma, Amanda Everitt, Rose Larios, Gina Williams, Shuyu Wang, Kim Long, Jeremy Willsey, Devanand Manoli
• Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.
  Cell 2016 Berendzen KM, Durieux J, Shao LW, Tian Y, Kim HE, Wolff S, Liu Y, Dillin A
• Poster Number: EI 6 Metabolism, Mitochondrial Stress, and Aging: How Neuroendocrine Signaling Coordinates Metabolic State in Aging and Neurodegenerative Disease Models.
  American Journal of Geriatric Psychiatry 2016 Kristen Berendzen, Jenni Durieux, Andrew Dillin
• Systemic stress signalling: understanding the cell non-autonomous control of proteostasis.
  Nature reviews. Molecular cell biology 2014 Taylor RC, Berendzen KM, Dillin A
• A combined therapeutic approach for pyruvate dehydrogenase deficiency using self-complementary adeno-associated virus serotype-specific vectors and dichloroacetate.
  Molecular genetics and metabolism 2008 Han Z, Berendzen K, Zhong L, Surolia I, Chouthai N, Zhao W, Maina N, Srivastava A, Stacpoole PW
• NMR investigation of metabolism in cultured human fibroblasts: Effects of PDC deficiency and DCA administration.
  Mitochondrion 2006 P.W. Stacpoole, N.E. Simpson, Z. Han, K.M. Berendzen, C.A. Sweeney, J.A. Oca-Cossio, I. Constantinidis
• Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.
  Mitochondrion 2006 K.M. Berendzen, D.W. Theriaque, J.J. Shuster, P.W. Stacpoole
• Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.
  Molecular genetics and metabolism 2006 Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW
• Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.
  Mitochondrion 2006 Berendzen K, Theriaque DW, Shuster J, Stacpoole PW
• 13C and 31P NMR investigation of pyruvate dehydrogenase complex (PDC)-deficient human fibroblasts.
  The FASEB Journal 2006 Nicholas Simpson, Zongchao Han, Kristen Berendzen, Carol Sweeney, Jose Oca-Cossio, Ioannis Constantinidis, Peter Stacpoole