Kondapa Naidu Bobba, PhD
Associate Researcher
Radiology
School of Medicine

Publications (24)

Top publication keywords:
Precision MedicineProstatic NeoplasmsRadiopharmaceuticalsPositron Emission Tomography Computed TomographyMembrane Cofactor ProteinMitochondriaTissue DistributionFluorescent DyesCopperHydrogen SulfideCoordination Complexes2,4-DinitrophenolRadioisotopesMuramic AcidsPositron-Emission Tomography

• CD46-Targeted Theranostics for PET and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Wadhwa A, Wang S, Patiño-Escobar B, Bidkar AP, Bobba KN, Chan E, Meher N, Bidlingmaier S, Su Y, Dhrona S, Geng H, Sarin V, VanBrocklin HF, Wilson DM, He J, Zhang L, Steri V, Wong SW, Martin TG, Seo Y,…
• Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection.
  JACS Au 2024 Sorlin AM, López-Álvarez M, Biboy J, Gray J, Rabbitt SJ, Rahim JU, Lee SH, Bobba KN, Blecha J, Parker MFL, Flavell RR, Engel J, Ohliger M, Vollmer W, Wilson DM
• Development of CD46 targeted alpha theranostics in prostate cancer using 134Ce/225Ac-Macropa-PEG4-YS5.
  Theranostics 2024 Bobba KN, Bidkar AP, Wadhwa A, Meher N, Drona S, Sorlin AM, Bidlingmaier S, Zhang L, Wilson DM, Chan E, Greenland NY, Aggarwal R, VanBrocklin HF, He J, Chou J, Seo Y, Liu B, Flavell RR
• Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers.
  ACS sensors 2023 Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM
• Coded aperture and Compton imaging for the development of 225 Ac-based radiopharmaceuticals.
  Medical physics 2023 Frame E, Bobba K, Gunter D, Mihailescu L, Bidkar A, Flavell R, Vetter K

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• Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo.
  Journal of the American Chemical Society 2023 Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, …
• Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects.
  ACS central science 2023 Klauser PC, Chopra S, Cao L, Bobba KN, Yu B, Seo Y, Chan E, Flavell RR, Evans MJ, Wang L
• Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from [ 18 F]FDG yield potent sensors of living bacteria in vivo.
  bioRxiv : the preprint server for biology 2023 Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, …
• Evaluation of 134Ce/134La as a PET Imaging Theranostic Pair for 225Ac α-Radiotherapeutics.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2023 Bobba KN, Bidkar AP, Meher N, Fong C, Wadhwa A, Dhrona S, Sorlin A, Bidlingmaier S, Shuere B, He J, Wilson DM, Liu B, Seo Y, VanBrocklin HF, Flavell RR
• Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Bidkar AP, Wang S, Bobba KN, Chan E, Bidlingmaier S, Egusa EA, Peter R, Ali U, Meher N, Wadhwa A, Dhrona S, Dasari C, Beckford-Vera D, Su Y, Tang R, Zhang L, He J, Wilson DM, Aggarwal R, VanBrocklin …
• Chalcone: A Promising Bioactive Scaffold in Medicinal Chemistry.
  Pharmaceuticals (Basel, Switzerland) 2022 Rajendran G, Bhanu D, Aruchamy B, Ramani P, Pandurangan N, Bobba KN, Oh EJ, Chung HY, Gangadaran P, Ahn BC
• Correction: A short PEG linker alters the in vivo pharmacokinetics of trastuzumab to yield high-contrast immuno-PET images.
  Journal of materials chemistry. B 2021 Lee W, Bobba KN, Kim JY, Park H, Bhise A, Kim W, Lee K, Rajkumar S, Nam B, Lee KC, Lee SH, Ko S, Lee HJ, Jung ST, Yoo J
• A short PEG linker alters the in vivo pharmacokinetics of trastuzumab to yield high-contrast immuno-PET images.
  Journal of materials chemistry. B 2021 Lee W, Bobba KN, Kim JY, Park H, Bhise A, Kim W, Lee K, Rajkumar S, Nam B, Lee KC, Lee SH, Ko S, Lee HJ, Jung ST, Yoo J
• Successful Application of CuAAC Click Reaction in Constructing 64Cu-Labeled Antibody Conjugates for Immuno-PET Imaging.
  ACS applied bio materials 2021 Lee W, Sarkar S, Pal R, Kim JY, Park H, Huynh PT, Bhise A, Bobba KN, Kim KI, Ha YS, Soni N, Kim W, Lee K, Jung JM, Rajkumar S, Lee KC, Yoo J
• Molecular Theranostic Agent with Programmed Activation for Hypoxic Tumors.
  ACS applied bio materials 2019 Koo S, Bobba KN, Cho MY, Park HS, Won M, Velusamy N, Hong KS, Bhuniya S, Kim JS
• Development of dansyl based copper(ii) complex to detect hydrogen sulfide in hypoxia.
  Organic & biomolecular chemistry 2019 Kim JY, Sarkar S, Bobba KN, Huynh PT, Bhise A, Yoo J
• Direct readout protonophore induced selective uncoupling and dysfunction of individual mitochondria within cancer cells.
  Chemical communications (Cambridge, England) 2019 Bobba KN, Binoy A, Koo S, Nedungadi D, Podder A, Sharma A, Mishra N, Kim JS, Bhuniya S
• Endogenous H2S-Assisted Cancer-Cell-Specific Activation of Theranostics with Emission Readout.
  ACS applied bio materials 2019 Bobba KN, Saranya G, Sujai PT, Joseph MM, Velusamy N, Podder A, Maiti KK, Bhuniya S
• FRET-based dual channel fluorescent probe for detecting endogenous/exogenous H2O2/H2S formation through multicolor images.
  Journal of photochemistry and photobiology. B, Biology 2018 Velusamy N, Thirumalaivasan N, Bobba KN, Podder A, Wu SP, Bhuniya S
• Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy.
  Journal of controlled release : official journal of the Controlled Release Society 2018 Zhou Y, Maiti M, Sharma A, Won M, Yu L, Miao LX, Shin J, Podder A, Bobba KN, Han J, Bhuniya S, Kim JS
• A bioorthogonal fluorescent probe for mitochondrial hydrogen sulfide: new strategy for cancer cell labeling.
  Chemical communications (Cambridge, England) 2017 Velusamy N, Binoy A, Bobba KN, Nedungadi D, Mishra N, Bhuniya S
• A bioorthogonal 'turn-on' fluorescent probe for tracking mitochondrial nitroxyl formation.
  Chemical communications (Cambridge, England) 2017 Sunwoo K, Bobba KN, Lim JY, Park T, Podder A, Heo JS, Lee SG, Bhuniya S, Kim JS
• A biotinylated piperazine-rhodol derivative: a 'turn-on' probe for nitroreductase triggered hypoxia imaging.
  The Analyst 2017 Zhou Y, Bobba KN, Lv XW, Yang D, Velusamy N, Zhang JF, Bhuniya S
• New Insight into a Cancer Theranostic Probe: Efficient Cell-Specific Delivery of SN-38 Guided by Biotinylated Poly(vinyl alcohol).
  ACS applied materials & interfaces 2016 Dutta D, Alex SM, Bobba KN, Maiti KK, Bhuniya S