Klaus Yserentant, PhD
Scientist II
Other
Chancellor/EVC/FAS

Publications (21)

Top publication keywords:
Single-Cell AnalysisMicroscopy, FluorescenceAdaptor Proteins, Signal TransducingClick ChemistryHeterochromatinOptical ImagingGlyceraldehyde-3-Phosphate DehydrogenasesPhotobleachingAmidesPhotonsChromosomal Proteins, Non-HistoneStaining and LabelingCarboxylic AcidsEuchromatinMammalian orthoreovirus 3

• De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles.
  Cell 2026 Chen Y, Yserentant K, Hong K, Chen K, Kuang Y, Picardo RS, Bhowmick A, Charles-Orszag A, Lord SJ, Lu L, Hou K, Mann SI, Bhattacharya S, Horst M, Grimm JB, Lavis LD, Mullins RD, DeGrado WF, Huang B
• Programming protein shape as an explicit design layer via CAD blueprint-guided diffusion.
  bioRxiv : the preprint server for biology 2026 Qi Y, Zhang G, Yserentant K, Lee S, Lyubimov A, Ibrahim K, Cimicata G, Fraser JS, Huang B, Kortemme T
• YAP charge patterning mediates signal integration through transcriptional co-condensates.
  Nature communications 2025 Meyer K, Yserentant K, Cheloor-Kovilakam R, Ruff KM, Chung CI, Shu X, Huang B, Weiner OD
• De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy.
  bioRxiv : the preprint server for biology 2025 Chen Y, Yserentant K, Hong K, Kuang Y, Bhowmick A, Charles-Orszag A, Lord SJ, Lu L, Hou K, Mann SI, Grimm JB, Lavis LD, Mullins RD, DeGrado WF, Huang B
• Accessible and accurate cytometry analysis of adherent cells using fluorescence microscopes.
  Scientific reports 2025 Foyt D, Kuang Y, Rehem S, Yserentant K, Huang B

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• Accessible and accurate cytometry analysis using fluorescence microscopes.
  bioRxiv : the preprint server for biology 2025 Foyt D, Kuang Y, Rehem S, Yserentant K, Huang B
• YAP charge patterning mediates signal integration through transcriptional co-condensates.
  bioRxiv : the preprint server for biology 2024 Meyer K, Yserentant K, Cheloor-Kovilakam R, Ruff KM, Chung CI, Shu X, Huang B, Weiner OD
• ProDOL: a general method to determine the degree of labeling for staining optimization and molecular counting.
  Nature methods 2024 Tashev SA, Euchner J, Yserentant K, Hänselmann S, Hild F, Chmielewicz W, Hummert J, Schwörer F, Tsopoulidis N, Germer S, Saßmannshausen Z, Fackler OT, Klingmüller U, Herten DP
• Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM.
  Proceedings of the National Academy of Sciences of the United States of America 2023 Choi W, Wu H, Yserentant K, Huang B, Cheng Y
• A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene.
  Biophysical reports 2022 Hild F, Werther P, Yserentant K, Wombacher R, Herten DP
• Mandipropamid as a chemical inducer of proximity for in vivo applications.
  Nature chemical biology 2021 Ziegler MJ, Yserentant K, Dunsing V, Middel V, Gralak AJ, Pakari K, Bargstedt J, Kern C, Petrich A, Chiantia S, Strähle U, Herten DP, Wombacher R
• Photobleaching step analysis for robust determination of protein complex stoichiometries.
  Molecular biology of the cell 2021 Hummert J, Yserentant K, Fink T, Euchner J, Ho YX, Tashev SA, Herten DP
• Bio-orthogonal Red and Far-Red Fluorogenic Probes for Wash-Free Live-Cell and Super-resolution Microscopy.
  ACS central science 2021 Werther P, Yserentant K, Braun F, Grußmayer K, Navikas V, Yu M, Zhang Z, Ziegler MJ, Mayer C, Gralak AJ, Busch M, Chi W, Rominger F, Radenovic A, Liu X, Lemke EA, Buckup T, Herten DP, Wombacher R
• Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy.
  Nature communications 2021 Navikas V, Leitao SM, Grussmayer KS, Descloux A, Drake B, Yserentant K, Werther P, Herten DP, Wombacher R, Radenovic A, Fantner GE
• Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation.
  Molecular cell 2020 Erdel F, Rademacher A, Vlijm R, Tünnermann J, Frank L, Weinmann R, Schweigert E, Yserentant K, Hummert J, Bauer C, Schumacher S, Al Alwash A, Normand C, Herten DP, Engelhardt J, Rippe K
• Forces during cellular uptake of viruses and nanoparticles at the ventral side.
  Nature communications 2020 Wiegand T, Fratini M, Frey F, Yserentant K, Liu Y, Weber E, Galior K, Ohmes J, Braun F, Herten DP, Boulant S, Schwarz US, Salaita K, Cavalcanti-Adam EA, Spatz JP
• Live-Cell Localization Microscopy with a Fluorogenic and Self-Blinking Tetrazine Probe.
  Angewandte Chemie (International ed. in English) 2019 Werther P, Yserentant K, Braun F, Kaltwasser N, Popp C, Baalmann M, Herten DP, Wombacher R
• Photons in - numbers out: perspectives in quantitative fluorescence microscopy for in situ protein counting.
  Methods and applications in fluorescence 2019 Grußmayer KS, Yserentant K, Herten DP
• Cell Fixation by Light-Triggered Release of Glutaraldehyde.
  Angewandte Chemie (International ed. in English) 2017 Schelkle KM, Schmid C, Yserentant K, Bender M, Wacker I, Petzoldt M, Hamburger M, Herten DP, Wombacher R, Schröder RR, Bunz UH
• Affinity, stoichiometry and cooperativity of heterochromatin protein 1 (HP1) binding to nucleosomal arrays.
  Journal of physics. Condensed matter : an Institute of Physics journal 2015 Teif VB, Kepper N, Yserentant K, Wedemann G, Rippe K
• Ca2+ dynamics correlates with phenotype and function in primary human neutrophils.
  Biophysical chemistry 2013 Hübner K, Surovtsova I, Yserentant K, Hänsch M, Kummer U