Kirsten Tolstrup, MD
Professor
Medicine
School of Medicine

Kirsten Tolstrup is a non-invasive cardiologist with special interest in echocardiography, valvular and structural heart disease. Her clinical interests include use of transthoracic echocardiography, transesophageal and three-dimensional transesophageal echocardiography and supine bicycle stress testing with echocardiography for the evaluation of cardiovascular disease in general and valvular heart disease in particular. Dr. Tolstrup works closely with the interventional team on transcatheter based procedures such as TAVR and MitraClip.

Academic Interests:

Dr. Tolstrup’s focus is on implementation of new noninvasive procedures and development of multidisciplinary team approach to cardiovascular care. Her research interests are primarily centered around valvular heart disease and echocardiography as they relate to clinical aspects.

• A Case-Based Discussion on the Management of Cryptogenic Stroke and Patent Foramen Ovale in the Patient With a Hypercoagulable Disorder.
  Journal of cardiothoracic and vascular anesthesia 2019 Gerstein NS, Clegg SD, Levin DB, Fish AC, Tolstrup K, Nakanishi K, Yoshida Y, Homma S
• Ratio of transmitral early filling velocity to early diastolic strain rate predicts long-term risk of cardiovascular morbidity and mortality in the general population.
  European heart journal 2019 Lassen MCH, Biering-Sørensen SR, Olsen FJ, Skaarup KG, Tolstrup K, Qasim AN, Møgelvang R, Jensen JS, Biering-Sørensen T
• Guidelines for the Use of Echocardiography in the Evaluation of a Cardiac Source of Embolism.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2016 Saric M, Armour AC, Arnaout MS, Chaudhry FA, Grimm RA, Kronzon I, Landeck BF, Maganti K, Michelena HI, Tolstrup K
• Lambl's Excrescences: Association with Cerebrovascular Disease and Pathogenesis.
  Cerebrovascular diseases (Basel, Switzerland) 2015 Roldan CA, Schevchuck O, Tolstrup K, Roldan PC, Macias L, Qualls CR, Greene ER, Hayek R, Charlton GA, Sibbitt WL
• Libman-Sacks Endocarditis: Detection, Characterization, and Clinical Correlates by Three-Dimensional Transesophageal Echocardiography.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2015 Roldan CA, Tolstrup K, Macias L, Qualls CR, Maynard D, Charlton G, Sibbitt WL
• Comparison of two-dimensional versus real-time three-dimensional transesophageal echocardiography for evaluation of patent foramen ovale morphology.
  The American journal of cardiology 2013 Tanaka J, Izumo M, Fukuoka Y, Saitoh T, Harada K, Harada K, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T
• Comparison of real-time three-dimensional transesophageal echocardiography to two-dimensional transesophageal echocardiography for quantification of mitral valve prolapse in patients with severe mitral regurgitation.
  The American journal of cardiology 2012 Izumo M, Shiota M, Kar S, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T
• Non-circular shape of right ventricular outflow tract: a real-time 3-dimensional transesophageal echocardiography study.
  Circulation. Cardiovascular imaging 2012 Izumo M, Shiota M, Saitoh T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T
• Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion.
  The American journal of cardiology 2012 Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T
• Comparison of left ventricular outflow geometry and aortic valve area in patients with aortic stenosis by 2-dimensional versus 3-dimensional echocardiography.
  The American journal of cardiology 2012 Saitoh T, Shiota M, Izumo M, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T
• Left atrial size and function are related to pulmonary hypertension in coronary artery disease.
  Echocardiography (Mount Kisco, N.Y.) 2012 Miyata-Fukuoka Y, Izumo M, Shimada Y, Kuwahara E, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T
• Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product.
  European heart journal. Cardiovascular Imaging 2012 Nalawadi SS, Tolstrup K, Cuk O, Shiota T, Gurudevan SV, Siegel RJ, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California
• Left atrial myxomas: correlation of two-dimensional and live three-dimensional transesophageal echocardiography with the clinical and pathologic findings.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2011 Tolstrup K, Shiota T, Gurudevan S, Luthringer D, Luo H, Siegel RJ
• Utility of three-dimensional transesophageal echocardiography in the diagnosis of valvular perforations.
  The American journal of cardiology 2011 Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ
• Septal thrombus in the left atrium: is the left atrial septal pouch the culprit?
  JACC. Cardiovascular imaging 2010 Gurudevan SV, Shah H, Tolstrup K, Siegel R, Krishnan SC
• Morphologic features of carcinoid heart disease as assessed by three-dimensional transesophageal echocardiography.
  Echocardiography (Mount Kisco, N.Y.) 2010 Nalawadi SS, Siegel RJ, Wolin E, Yu R, Trento A, Shiota T, Tolstrup K, Luthringer D, Gurudevan S
• Diastolic dysfunction: improved understanding using emerging imaging techniques.
  American heart journal 2010 Daneshvar D, Wei J, Tolstrup K, Thomson LE, Shufelt C, Merz CN
• Reproducibility of proximal isovelocity surface area, vena contracta, and regurgitant jet area for assessment of mitral regurgitation severity.
  JACC. Cardiovascular imaging 2010 Biner S, Rafique A, Rafii F, Tolstrup K, Noorani O, Shiota T, Gurudevan S, Siegel RJ
• Meta-analysis of prognostic value of stress testing in patients with asymptomatic severe aortic stenosis.
  The American journal of cardiology 2009 Rafique AM, Biner S, Ray I, Forrester JS, Tolstrup K, Siegel RJ
• Aortopathy is prevalent in relatives of bicuspid aortic valve patients.
  Journal of the American College of Cardiology 2009 Biner S, Rafique AM, Ray I, Cuk O, Siegel RJ, Tolstrup K
• Visual assessment of left ventricular dyssynchrony using tissue synchronization imaging.
  Cardiology 2009 Biner S, Rafique AM, Wolak A, Tolstrup K, Siegel RJ
• Predictors of reduction in mitral regurgitation in patients undergoing cardiac resynchronisation treatment.
  Heart (British Cardiac Society) 2008 Naqvi TZ, Rafique AM, Swerdlow C, Verma S, Siegel RJ, Tolstrup K, Kerwin W, Goodman J, Gallik D, Gang E, Peter CT
• Thoracic aortic arteriosclerosis in patients with degenerative aortic stenosis with and without coexisting coronary artery disease.
  The Annals of thoracic surgery 2008 Goland S, Trento A, Czer LS, Eshaghian S, Tolstrup K, Naqvi TZ, De Robertis MA, Mirocha J, Iida K, Siegel RJ
• Chlamydia pneumoniae antibody titers and cardiac calcifications: a cross-sectional serological-echocardiographic correlative study.
  The Israel Medical Association journal : IMAJ 2007 Atar S, Tolstrup K, Cercek B, Siegel RJ
• Assessment of aortic stenosis by three-dimensional echocardiography: an accurate and novel approach.
  Heart (British Cardiac Society) 2007 Goland S, Trento A, Iida K, Czer LS, De Robertis M, Naqvi TZ, Tolstrup K, Akima T, Luo H, Siegel RJ
• Stress echocardiography in octogenarians: transesophageal atrial pacing is accurate, safe, and well tolerated.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006 Kobal SL, Pollick C, Atar S, Miyamoto T, Aslanian N, Neuman Y, Tolstrup K, Naqvi TZ, Luo H, Macrum B, Siegel RJ
• Non-invasive resting magnetocardiographic imaging for the rapid detection of ischemia in subjects presenting with chest pain.
  Cardiology 2006 Tolstrup K, Madsen BE, Ruiz JA, Greenwood SD, Camacho J, Siegel RJ, Gertzen HC, Park JW, Smars PA
• Comparison of effectiveness of hand-carried ultrasound to bedside cardiovascular physical examination.
  The American journal of cardiology 2005 Kobal SL, Trento L, Baharami S, Tolstrup K, Naqvi TZ, Cercek B, Neuman Y, Mirocha J, Kar S, Forrester JS, Siegel RJ
• Pseudomyxoma originating from the interatrial septum in a heart transplant patient.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2005 Neuman Y, Tolstrup K, Blanche C, Luthringer D, Kobal S, Miyamoto T, Luo H, Siegel RJ
• Comparison of frequency of left ventricular wall motion abnormalities in patients with a first acute myocardial infarction with versus without left ventricular hypertrophy.
  The American journal of cardiology 2004 Neuman Y, Cercek B, Aragon J, Lee S, Kobal S, Miyamoto T, Luo H, Tolstrup K, Naqvi TZ, Birnbaum Y, Siegel RJ
• Usefulness of a hand-carried cardiac ultrasound device for bedside examination of pericardial effusion in patients after cardiac surgery.
  The American journal of cardiology 2004 Luo H, Chen M, Trento A, Miyamoto T, Kobal SL, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ
• Usefulness of a hand-carried cardiac ultrasound device to detect clinically significant valvular regurgitation in hospitalized patients.
  The American journal of cardiology 2004 Kobal SL, Tolstrup K, Luo H, Neuman Y, Miyamoto T, Mirocha J, Naqvi TZ, Siegel RJ
• Correlation of echo-Doppler aortic valve regurgitation index with angiographic aortic regurgitation severity.
  The American journal of cardiology 2003 Chen M, Luo H, Miyamoto T, Atar S, Kobal S, Rahban M, Brasch AV, Makkar R, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ
• Aortic valve sclerosis, mitral annular calcium, and aortic root sclerosis as markers of atherosclerosis in men.
  The American journal of cardiology 2002 Tolstrup K, Roldan CA, Qualls CR, Crawford MH