Kimberly Rickman, MD, PhD
Clinical Fellow
Medicine
School of Medicine

Education & Training

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• Internal Medicine University of California, San Francisco 07/2022
• MD Medicine Weill Cornell Medical College 05/2020
• PhD Genetics, Molecular Biology, DNA Repair The Rockefeller University 08/2019
• Hematology and Oncology University of California, San Francisco

Publications (10)

Top publication keywords:
DNA DamageFanconi AnemiaBRCA2 ProteinDNA ReplicationDNAFanconi Anemia Complementation Group D2 ProteinSulfatesIsoniazidWater PurificationFanconi Anemia Complementation Group L ProteinDNA Repairbeta-LactamsHydroxyl RadicalUbiquitin-Conjugating EnzymesCell Nucleus

• A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype.
  Haematologica 2021 Schultz-Rogers L, Lach FP, Rickman KA, Ferrer A, Mangaonkar AA, Schwab TL, Schmitz CT, Clark KJ, Dsouza NR, Zimmermann MT, Litzow M, Jacobi N, Klee EW, Smogorzewska A, Patnaik MM
• Esophageal cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant.
  Cold Spring Harbor molecular case studies 2020 Lach FP, Singh S, Rickman KA, Ruiz PD, Noonan RJ, Hymes KB, DeLacure MD, Kennedy JA, Chandrasekharappa SC, Smogorzewska A
• Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
  Genes & development 2020 Rickman KA, Noonan RJ, Lach FP, Sridhar S, Wang AT, Abhyankar A, Huang A, Kelly M, Auerbach AD, Smogorzewska A
• Advances in understanding DNA processing and protection at stalled replication forks.
  The Journal of cell biology 2019 Rickman K, Smogorzewska A
• S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.
  Molecular cell 2017 Lv Z, Rickman KA, Yuan L, Williams K, Selvam SP, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK

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• Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.
  Cell reports 2015 Rickman KA, Lach FP, Abhyankar A, Donovan FX, Sanborn EM, Kennedy JA, Sougnez C, Gabriel SB, Elemento O, Chandrasekharappa SC, Schindler D, Auerbach AD, Smogorzewska A
• Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.
  Molecular cell 2014 Ouyang J, Garner E, Hallet A, Nguyen HD, Rickman KA, Gill G, Smogorzewska A, Zou L
• Isoniazid: Radical-induced oxidation and reduction chemistry.
  Bioorganic & medicinal chemistry letters 2013 Rickman KA, Swancutt KL, Mezyk SP, Kiddle JJ
• Reaction kinetics and efficiencies for the hydroxyl and sulfate radical based oxidation of artificial sweeteners in water.
  The journal of physical chemistry. A 2012 Toth JE, Rickman KA, Venter AR, Kiddle JJ, Mezyk SP
• Kinetics and mechanisms of sulfate radical oxidation of β-lactam antibiotics in water.
  Chemosphere 2010 Rickman KA, Mezyk SP