Kiichiro Tomoda, PhD
Research Investigator
Business Service Ctr
Chancellor/EVC/FAS
Publications (27)
Top publication keywords:
Pluripotent Stem CellsBlastocystInduced Pluripotent Stem CellsTranscription FactorsCellular Reprogramming TechniquesCellular ReprogrammingLeukemia Inhibitory FactorPhosphoric Diester HydrolasesGerm LayersEmbryonic Stem CellsEmbryo, MammalianCell Culture TechniquesLysophospholipidsBone Morphogenetic Protein 4Embryo Implantation
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The cytotoxicity of gefitinib on patient‑derived induced pluripotent stem cells reflects gefitinib‑induced liver injury in the clinical setting.
Oncology letters 2023 Fujisaka Y, Nakagawa T, Tomoda K, Watanabe M, Matsunaga N, Tamura Y, Ikeda S, Imagawa A, Asahi M -
Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells.
Developmental cell 2023 Vasic I, Libby ARG, Maslan A, Bulger EA, Zalazar D, Krakora Compagno MZ, Streets A, Tomoda K, Yamanaka S, McDevitt TC -
Non-thermal atmospheric-pressure plasma potentiates mesodermal differentiation of human induced pluripotent stem cells.
Heliyon 2022 Kobayashi M, Tomoda K, Morihara H, Asahi M, Shimizu T, Kumagai S -
Corrigendum to "ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages" [Bone. 153 2021 Dec; 116129. doi:10.1016/j.bone.2021.116129. Epub 2021 Jul 24. PMID: 34311122].
Bone 2022 Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC -
ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages.
Bone 2021 Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC
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Reprogramming epiblast stem cells into pre-implantation blastocyst cell-like cells.
Stem cell reports 2021 Tomoda K, Hu H, Sahara Y, Sanyal H, Takasato M, Kime C -
Synthetic embryology: Early mammalian embryo modeling systems from cell cultures.
Development, growth & differentiation 2021 Tomoda K, Kime C -
Fluctuation in O-GlcNAcylation inactivates STIM1 to reduce store-operated calcium ion entry via down-regulation of Ser621 phosphorylation.
The Journal of biological chemistry 2020 Nomura A, Yokoe S, Tomoda K, Nakagawa T, Martin-Romero FJ, Asahi M -
Intravenously Injected Pluripotent Stem Cell-derived Cells Form Fetomaternal Vasculature and Prevent Miscarriage in Mouse.
Cell transplantation 2020 Daimon A, Morihara H, Tomoda K, Morita N, Koishi Y, Kanki K, Ohmichi M, Asahi M -
Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK.
The Journal of biological chemistry 2019 Wakabayashi S, Morihara H, Yokoe S, Nakagawa T, Moriwaki K, Tomoda K, Asahi M -
Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells.
Stem cell reports 2019 Kime C, Kiyonari H, Ohtsuka S, Kohbayashi E, Asahi M, Yamanaka S, Takahashi M, Tomoda K -
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
Proceedings of the National Academy of Sciences of the United States of America 2016 Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S -
Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program.
Proceedings of the National Academy of Sciences of the United States of America 2016 Kime C, Sakaki-Yumoto M, Goodrich L, Hayashi Y, Sami S, Derynck R, Asahi M, Panning B, Yamanaka S, Tomoda K -
Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells.
Current protocols in human genetics 2015 Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K -
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2015 Hayashi Y, Caboni L, Das D, Yumoto F, Clayton T, Deller MC, Nguyen P, Farr CL, Chiu HJ, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Tomoda K, Conklin BR, Wilson IA, Yamanaka S, Fletterick … -
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.
Stem cell reports 2014 Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, January CT, Healy KE, Kamp TJ,… -
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells.
Cell stem cell 2012 Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S -
G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies.
PloS one 2009 Nakamura K, Salomonis N, Tomoda K, Yamanaka S, Conklin BR -
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Cell 2007 Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S -
Preparation and characterization of monoclonal antibodies against mouse Jab1/CSN5 protein.
Hybridoma (2005) 2006 Kato JY, Nakamae I, Tomoda K, Fukumoto A, Yoneda-Kato N -
Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines.
FEBS letters 2006 Fukumoto A, Tomoda K, Yoneda-Kato N, Nakajima Y, Kato JY -
Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.
The EMBO journal 2005 Yoneda-Kato N, Tomoda K, Umehara M, Arata Y, Kato JY -
Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation.
FEBS letters 2005 Fukumoto A, Tomoda K, Kubota M, Kato JY, Yoneda-Kato N -
The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression.
Blood 2004 Tomoda K, Kato JY, Tatsumi E, Takahashi T, Matsuo Y, Yoneda-Kato N -
Multiple functions of Jab1 are required for early embryonic development and growth potential in mice.
The Journal of biological chemistry 2004 Tomoda K, Yoneda-Kato N, Fukumoto A, Yamanaka S, Kato JY -
Prognostic significance of localized p27Kip1 and potential role of Jab1/CSN5 in pancreatic cancer.
Oncology reports 2004 Fukumoto A, Ikeda N, Sho M, Tomoda K, Kanehiro H, Hisanaga M, Tsurui Y, Tsutsumi M, Kato JY, Nakajima Y -
The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex.
The Journal of biological chemistry 2001 Tomoda K, Kubota Y, Arata Y, Mori S, Maeda M, Tanaka T, Yoshida M, Yoneda-Kato N, Kato JY