Kathleen Lamborn, PhD
Professor Emeritus
Neurological Surgery
School of Medicine

Grants and Projects

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• Brain Tumor SPORE Grant, NIH, 2002-2023
• Cancer Center Support Grant, NIH, 1999-2023
• Translational Multimodality " Antibody" Therapy, NIH, 1988-2009

Publications (208)

Top publication keywords:
Iodine RadioisotopesNeoplasm Recurrence, LocalGlioblastomaLymphoma, Non-HodgkinQuinazolinesAntineoplastic AgentsRadioimmunotherapyAntibodies, MonoclonalSupratentorial NeoplasmsBrain NeoplasmsDacarbazineClinical Trials, Phase II as TopicDisease-Free SurvivalGliomaHeterocyclic Compounds

• Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02.
  Neuro-oncology advances 2020 Chen H, Kuhn J, Lamborn KR, Abrey LE, DeAngelis LM, Lieberman F, Robins HI, Chang SM, Yung WKA, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Wen PY, Gilbert…
• Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02.
  Neuro-oncology 2014 Wen PY, Chang SM, Lamborn KR, Kuhn JG, Norden AD, Cloughesy TF, Robins HI, Lieberman FS, Gilbert MR, Mehta MP, Drappatz J, Groves MD, Santagata S, Ligon AH, Yung WK, Wright JJ, Dancey J, Aldape KD, …
• Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group.
  The Lancet. Oncology 2013 Lin NU, Lee EQ, Aoyama H, Barani IJ, Baumert BG, Brown PD, Camidge DR, Chang SM, Dancey J, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Lamborn KR, Linskey ME, Macdonald DR, Margolin K, Mehta MP, …
• Visual field defects after radiosurgery for mesial temporal lobe epilepsy.
  Epilepsia 2013 Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R
• Survival analysis in patients with newly diagnosed glioblastoma using pre- and postradiotherapy MR spectroscopic imaging.
  Neuro-oncology 2013 Li Y, Lupo JM, Parvataneni R, Lamborn KR, Cha S, Chang SM, Nelson SJ

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• Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02.
  Neuro-oncology 2012 Lee EQ, Kuhn J, Lamborn KR, Abrey L, DeAngelis LM, Lieberman F, Robins HI, Chang SM, Yung WK, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Gilbert MR, Wen …
• Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Lee EQ, Puduvalli VK, Reid JM, Kuhn JG, Lamborn KR, Cloughesy TF, Chang SM, Drappatz J, Yung WK, Gilbert MR, Robins HI, Lieberman FS, Lassman AB, McGovern RM, Xu J, Desideri S, Ye X, Ames MM, Espinoza…
• Phase 2 trial design in neuro-oncology revisited: a report from the RANO group.
  The Lancet. Oncology 2012 Galanis E, Wu W, Cloughesy T, Lamborn K, Mann B, Wen PY, Reardon DA, Wick W, Macdonald D, Armstrong TS, Weller M, Vogelbaum M, Colman H, Sargent DJ, van den Bent MJ, Gilbert M, Chang S
• Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors.
  Cancer discovery 2012 Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, Nghiemphu PL, Kubek S, Oldrini B, Chheda MG, Yannuzzi N, Tao H, Zhu S, Iwanami A, Kuga D, Dang J, Pedraza A, Brennan CW, Heguy A, Liau LM, Lieberman…
• The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.
  Journal of neuro-oncology 2012 Schoenfeld A, Pekmezci M, Barnes MJ, Tihan T, Gupta N, Lamborn KR, Banerjee A, Mueller S, Chang S, Berger MS, Haas-Kogan D
• Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment.
  Neurosurgery 2012 Clark AJ, Lamborn KR, Butowski NA, Chang SM, Prados MD, Clarke JL, McDermott MW, Parsa AT, Berger MS, Aghi MK
• Spatial characteristics of newly diagnosed grade 3 glioma assessed by magnetic resonance metabolic and diffusion tensor imaging.
  Translational oncology 2012 Ozturk-Isik E, Pirzkall A, Lamborn KR, Cha S, Chang SM, Nelson SJ
• Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy.
  International journal of radiation oncology, biology, physics 2011 Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura JL, Barani IJ, McDermott MW
• Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes.
  Neurosurgery 2011 Potts MB, Jahangiri A, Lamborn KR, Blevins LS, Kunwar S, Aghi MK
• Conditional probability of survival in patients with newly diagnosed glioblastoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Polley MY, Lamborn KR, Chang SM, Butowski N, Clarke JL, Prados M
• Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
  Neuro-oncology 2011 Butowski N, Chang SM, Lamborn KR, Polley MY, Pieper R, Costello JF, Vandenberg S, Parvataneni R, Nicole A, Sneed PK, Clarke J, Hsieh E, Costa BM, Reis RM, Hristova-Kazmierski M, Nicol SJ, Thornton DE,…
• Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?
  Neuro-oncology 2011 Clarke JL, Ennis MM, Yung WK, Chang SM, Wen PY, Cloughesy TF, Deangelis LM, Robins HI, Lieberman FS, Fine HA, Abrey L, Gilbert MR, Mehta M, Kuhn JG, Aldape KD, Lamborn KR, Prados MD, North American …
• Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery.
  Journal of neuro-oncology 2011 Gilbert MR, Kuhn J, Lamborn KR, Lieberman F, Wen PY, Mehta M, Cloughesy T, Lassman AB, Deangelis LM, Chang S, Prados M
• Factors associated with delay to pituitary adenoma diagnosis in patients with visual loss.
  Journal of neurosurgery 2011 Jahangiri A, Lamborn KR, Blevins L, Kunwar S, Aghi MK
• Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 de Groot JF, Lamborn KR, Chang SM, Gilbert MR, Cloughesy TF, Aldape K, Yao J, Jackson EF, Lieberman F, Robins HI, Mehta MP, Lassman AB, Deangelis LM, Yung WK, Chen A, Prados MD, Wen PY
• Neuropsychological outcomes after Gamma Knife radiosurgery for mesial temporal lobe epilepsy: a prospective multicenter study.
  Epilepsia 2011 Quigg M, Broshek DK, Barbaro NM, Ward MM, Laxer KD, Yan G, Lamborn K, Radiosurgery Epilepsy Study Group
• A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03.
  Neuro-oncology 2011 Iwamoto FM, Lamborn KR, Kuhn JG, Wen PY, Yung WK, Gilbert MR, Chang SM, Lieberman FS, Prados MD, Fine HA
• Identifying the needs of brain tumor patients and their caregivers.
  Journal of neuro-oncology 2011 Parvataneni R, Polley MY, Freeman T, Lamborn K, Prados M, Butowski N, Liu R, Clarke J, Page M, Rabbitt J, Fedoroff A, Clow E, Hsieh E, Kivett V, Deboer R, Chang S
• Clinical trial end points for high-grade glioma: the evolving landscape.
  Neuro-oncology 2011 Reardon DA, Galanis E, DeGroot JF, Cloughesy TF, Wefel JS, Lamborn KR, Lassman AB, Gilbert MR, Sampson JH, Wick W, Chamberlain MC, Macdonald DR, Mehta MP, Vogelbaum MA, Chang SM, Van den Bent MJ, Wen …
• A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
  International journal of radiation oncology, biology, physics 2010 Nghiemphu PL, Wen PY, Lamborn KR, Drappatz J, Robins HI, Fink K, Malkin MG, Lieberman FS, DeAngelis LM, Torres-Trejo A, Chang SM, Abrey L, Fine HA, Demopoulos A, Lassman AB, Kesari S, Mehta MP, Prados…
• Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Wen PY, Macdonald DR, Reardon DA, Cloughesy TF, Sorensen AG, Galanis E, Degroot J, Wick W, Gilbert MR, Lassman AB, Tsien C, Mikkelsen T, Wong ET, Chamberlain MC, Stupp R, Lamborn KR, Vogelbaum MA, van…
• Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.
  Journal of neuro-oncology 2010 Mishra KK, Squire S, Lamborn K, Banerjee A, Gupta N, Wara WM, Prados MD, Berger MS, Haas-Kogan DA
• Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02).
  Neuro-oncology 2010 Iwamoto FM, Lamborn KR, Robins HI, Mehta MP, Chang SM, Butowski NA, Deangelis LM, Abrey LE, Zhang WT, Prados MD, Fine HA
• Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
  Neuro-oncology 2010 Butowski N, Chang SM, Lamborn KR, Polley MY, Parvataneni R, Hristova-Kazmierski M, Musib L, Nicol SJ, Thornton DE, Prados MD
• Joint NCCTG and NABTC prognostic factors analysis for high-grade recurrent glioma.
  Neuro-oncology 2009 Wu W, Lamborn KR, Buckner JC, Novotny PJ, Chang SM, O'Fallon JR, Jaeckle KA, Prados MD
• Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
  Neuro-oncology 2009 Polley MY, Lamborn KR, Chang SM, Butowski N, Clarke JL, Prados M
• A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas.
  Neuro-oncology 2009 Raizer JJ, Abrey LE, Lassman AB, Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Aldape KD, Wen PY, Fine HA, Mehta M, Deangelis LM, Lieberman F, Cloughesy TF, Robins HI, Dancey J, Prados MD, North…
• A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy.
  Neuro-oncology 2009 Raizer JJ, Abrey LE, Lassman AB, Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Aldape KA, Wen PY, Fine HA, Mehta M, Deangelis LM, Lieberman F, Cloughesy TF, Robins HI, Dancey J, Prados MD, North…
• Multiparametric characterization of grade 2 glioma subtypes using magnetic resonance spectroscopic, perfusion, and diffusion imaging.
  Translational oncology 2009 Bian W, Khayal IS, Lupo JM, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).
  Neuro-oncology 2009 Wen PY, Yung WK, Lamborn KR, Norden AD, Cloughesy TF, Abrey LE, Fine HA, Chang SM, Robins HI, Fink K, Deangelis LM, Mehta M, Di Tomaso E, Drappatz J, Kesari S, Ligon KL, Aldape K, Jain RK, Stiles CD, …
• Tumor regrowth between surgery and initiation of adjuvant therapy in patients with newly diagnosed glioblastoma.
  Neuro-oncology 2009 Pirzkall A, McGue C, Saraswathy S, Cha S, Liu R, Vandenberg S, Lamborn KR, Berger MS, Chang SM, Nelson SJ
• Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.
  Journal of neuro-oncology 2009 McBride SM, Perez DA, Polley MY, Vandenberg SR, Smith JS, Zheng S, Lamborn KR, Wiencke JK, Chang SM, Prados MD, Berger MS, Stokoe D, Haas-Kogan DA
• Radiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD.
  Free radical biology & medicine 2009 Fishman K, Baure J, Zou Y, Huang TT, Andres-Mach M, Rola R, Suarez T, Acharya M, Limoli CL, Lamborn KR, Fike JR
• Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma.
  Journal of neuro-oncology 2009 Norden AD, Raizer JJ, Abrey LE, Lamborn KR, Lassman AB, Chang SM, Yung WK, Gilbert MR, Fine HA, Mehta M, Deangelis LM, Cloughesy TF, Robins HI, Aldape K, Dancey J, Prados MD, Lieberman F, Wen PY
• Adjuvant enoxaparin therapy may decrease the incidence of postoperative thrombotic events though does not increase the incidence of postoperative intracranial hemorrhage in patients with meningiomas.
  Journal of neuro-oncology 2009 Cage TA, Lamborn KR, Ware ML, Frankfurt A, Chakalian L, Berger MS, McDermott MW
• Apparent diffusion coefficient and fractional anisotropy of newly diagnosed grade II gliomas.
  NMR in biomedicine 2009 Khayal IS, McKnight TR, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• A multicenter, prospective pilot study of gamma knife radiosurgery for mesial temporal lobe epilepsy: seizure response, adverse events, and verbal memory.
  Annals of neurology 2009 Barbaro NM, Quigg M, Broshek DK, Ward MM, Lamborn KR, Laxer KD, Larson DA, Dillon W, Verhey L, Garcia P, Steiner L, Heck C, Kondziolka D, Beach R, Olivero W, Witt TC, Salanova V, Goodman R
• Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.
  Journal of neuro-oncology 2009 Lim DA, Tarapore P, Chang E, Burt M, Chakalian L, Barbaro N, Chang S, Lamborn KR, McDermott MW
• Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Prados MD, Chang SM, Butowski N, DeBoer R, Parvataneni R, Carliner H, Kabuubi P, Ayers-Ringler J, Rabbitt J, Page M, Fedoroff A, Sneed PK, Berger MS, McDermott MW, Parsa AT, Vandenberg S, James CD, …
• Prognostic factors and grading systems for overall survival in patients treated with radiosurgery for brain metastases: variation by primary site.
  Journal of neurosurgery 2008 Golden DW, Lamborn KR, McDermott MW, Kunwar S, Wara WM, Nakamura JL, Sneed PK
• Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM.
  Journal of neuro-oncology 2008 Crawford FW, Khayal IS, McGue C, Saraswathy S, Pirzkall A, Cha S, Lamborn KR, Chang SM, Berger MS, Nelson SJ
• Preoperative prognostic classification system for hemispheric low-grade gliomas in adults.
  Journal of neurosurgery 2008 Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, Barbaro NM, Parsa AT, Berger MS, McDermott MM
• A North American brain tumor consortium phase II study of poly-ICLC for adult patients with recurrent anaplastic gliomas.
  Journal of neuro-oncology 2008 Butowski N, Lamborn KR, Lee BL, Prados MD, Cloughesy T, DeAngelis LM, Abrey L, Fink K, Lieberman F, Mehta M, Ian Robins H, Junck L, Salazar AM, Chang SM
• Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy.
  Journal of neuro-oncology 2008 Saraswathy S, Crawford FW, Lamborn KR, Pirzkall A, Chang S, Cha S, Nelson SJ
• A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05).
  Journal of neuro-oncology 2008 Butowski N, Chang SM, Junck L, DeAngelis LM, Abrey L, Fink K, Cloughesy T, Lamborn KR, Salazar AM, Prados MD
• Signal transduction molecules in gliomas of all grades.
  Journal of neuro-oncology 2008 Ermoian RP, Kaprealian T, Lamborn KR, Yang X, Jelluma N, Arvold ND, Zeidman R, Berger MS, Stokoe D, Haas-Kogan DA
• In reference to lamborn et Al. (Neuro-oncology. 2008;10:162-170).
  Neuro-oncology 2008 Meyers CA, Lamborn KR, Prados MD
• Quality of life in low-grade glioma patients receiving temozolomide.
  Neuro-oncology 2008 Liu R, Solheim K, Polley MY, Lamborn KR, Page M, Fedoroff A, Rabbitt J, Butowski N, Prados M, Chang SM
• Neurooncology clinical trial design for targeted therapies: lessons learned from the North American Brain Tumor Consortium.
  Neuro-oncology 2008 Chang SM, Lamborn KR, Kuhn JG, Yung WK, Gilbert MR, Wen PY, Fine HA, Mehta MP, DeAngelis LM, Lieberman FS, Cloughesy TF, Robins HI, Abrey LE, Prados MD, North American Brain Tumor Consortium
• Hippocampal neurogenesis and neuroinflammation after cranial irradiation with (56)Fe particles.
  Radiation research 2008 Rola R, Fishman K, Baure J, Rosi S, Lamborn KR, Obenaus A, Nelson GA, Fike JR
• Radiation is an important component of multimodality therapy for pediatric non-pineal supratentorial primitive neuroectodermal tumors.
  International journal of radiation oncology, biology, physics 2008 McBride SM, Daganzo SM, Banerjee A, Gupta N, Lamborn KR, Prados MD, Berger MS, Wara WM, Haas-Kogan DA
• Long-term recurrence and mortality after surgery and adjuvant radiotherapy for nonfunctional pituitary adenomas.
  Journal of neurosurgery 2008 Chang EF, Zada G, Kim S, Lamborn KR, Quinones-Hinojosa A, Tyrrell JB, Wilson CB, Kunwar S
• Relationship between choline and apparent diffusion coefficient in patients with gliomas.
  Journal of magnetic resonance imaging : JMRI 2008 Khayal IS, Crawford FW, Saraswathy S, Lamborn KR, Chang SM, Cha S, McKnight TR, Nelson SJ
• Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS
• Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas.
  Neuro-oncology 2008 Lamborn KR, Yung WK, Chang SM, Wen PY, Cloughesy TF, DeAngelis LM, Robins HI, Lieberman FS, Fine HA, Fink KL, Junck L, Abrey L, Gilbert MR, Mehta M, Kuhn JG, Aldape KD, Hibberts J, Peterson PM, Prados…
• New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.
  Neuro-oncology 2008 Hashizume R, Ozawa T, Gryaznov SM, Bollen AW, Lamborn KR, Frey WH, Deen DF
• Seizure characteristics and control following resection in 332 patients with low-grade gliomas.
  Journal of neurosurgery 2008 Chang EF, Potts MB, Keles GE, Lamborn KR, Chang SM, Barbaro NM, Berger MS
• Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome.
  Neurosurgery 2008 Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA
• Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Kuhn JG, Chang SM, Wen PY, Cloughesy TF, Greenberg H, Schiff D, Conrad C, Fink KL, Robins HI, Mehta M, DeAngelis L, Raizer J, Hess K, Lamborn KR, Dancey J, Prados MD, North American Brain Tumor …
• Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Loghin ME, Prados MD, Wen P, Junck L, Lieberman F, Fine H, Fink KL, Metha M, Kuhn J, Lamborn K, Chang SM, Cloughesy T, DeAngelis LM, Robins IH, Aldape KD, Yung WK
• Effect of antilymphoma antibody, 131I-Lym-1, on peripheral blood lymphocytes in patients with non-Hodgkin's lymphoma.
  Cancer biotherapy & radiopharmaceuticals 2007 Schillaci O, DeNardo GL, DeNardo SJ, Goldstein DS, Kroger LA, O'Donnell RT, Lamborn KR
• Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.
  AJNR. American journal of neuroradiology 2007 Cha S, Lupo JM, Chen MH, Lamborn KR, McDermott MW, Berger MS, Nelson SJ, Dillon WP
• Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2007 Chen AM, Chang S, Pouliot J, Sneed PK, Prados MD, Lamborn KR, Malec MK, McDermott MW, Berger MS, Larson DA
• Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma.
  Neuro-oncology 2007 Wiencke JK, Zheng S, Jelluma N, Tihan T, Vandenberg S, Tamgüney T, Baumber R, Parsons R, Lamborn KR, Berger MS, Wrensch MR, Haas-Kogan DA, Stokoe D
• Historical controls for phase II surgically based trials requiring gross total resection of glioblastoma multiforme.
  Journal of neuro-oncology 2007 Butowski N, Lamborn KR, Berger MS, Prados MD, Chang SM
• Correlation of magnetic resonance spectroscopic and growth characteristics within Grades II and III gliomas.
  Journal of neurosurgery 2007 McKnight TR, Lamborn KR, Love TD, Berger MS, Chang S, Dillon WP, Bollen A, Nelson SJ
• Cytosine deaminase/5-fluorocytosine exposure induces bystander and radiosensitization effects in hypoxic glioblastoma cells in vitro.
  International journal of radiation oncology, biology, physics 2007 Chen JK, Hu LJ, Wang D, Lamborn KR, Deen DF
• Treatment for posterior fossa dissemination of primary supratentorial glioma.
  Journal of neurosurgery 2007 Smith JS, Parney IF, Lamborn KR, McDermott MW, Sneed PK, Chang SM
• In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas.
  Neuro-oncology 2007 Entin-Meer M, Yang X, VandenBerg SR, Lamborn KR, Nudelman A, Rephaeli A, Haas-Kogan DA
• Synthesis and comparative toxicology of a series of polyhedral borane anion-substituted tetraphenyl porphyrins.
  Journal of medicinal chemistry 2007 Koo MS, Ozawa T, Santos RA, Lamborn KR, Bollen AW, Deen DF, Kahl SB
• Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Yoo H, Baia GS, Smith JS, McDermott MW, Bollen AW, Vandenberg SR, Lamborn KR, Lal A
• A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
  Journal of neuro-oncology 2006 Groves MD, Puduvalli VK, Chang SM, Conrad CA, Gilbert MR, Tremont-Lukats IW, Liu TJ, Peterson P, Schiff D, Cloughesy TF, Wen PY, Greenberg H, Abrey LE, DeAngelis LM, Hess KR, Lamborn KR, Prados MD, …
• Response of intracerebral human glioblastoma xenografts to multifraction radiation exposures.
  International journal of radiation oncology, biology, physics 2006 Ozawa T, Faddegon BA, Hu LJ, Bollen AW, Lamborn KR, Deen DF
• Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Wen PY, Yung WK, Lamborn KR, Dahia PL, Wang Y, Peng B, Abrey LE, Raizer J, Cloughesy TF, Fink K, Gilbert M, Chang S, Junck L, Schiff D, Lieberman F, Fine HA, Mehta M, Robins HI, DeAngelis LM, Groves …
• Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006 Cloughesy TF, Wen PY, Robins HI, Chang SM, Groves MD, Fink KL, Junck L, Schiff D, Abrey L, Gilbert MR, Lieberman F, Kuhn J, DeAngelis LM, Mehta M, Raizer JJ, Yung WK, Aldape K, Wright J, Lamborn KR, …
• Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
  Journal of neurosurgery 2006 Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
• Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival.
  Cancer research 2006 Wrensch M, Wiencke JK, Wiemels J, Miike R, Patoka J, Moghadassi M, McMillan A, Kelsey KT, Aldape K, Lamborn KR, Parsa AT, Sison JD, Prados MD
• A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
  Neuro-oncology 2006 Prados MD, Lamborn K, Yung WK, Jaeckle K, Robins HI, Mehta M, Fine HA, Wen PY, Cloughesy T, Chang S, Nicholas MK, Schiff D, Greenberg H, Junck L, Fink K, Hess K, Kuhn J, North American Brain Tumor …
• Prognostic value of detecting recurrent glioblastoma multiforme in surgical specimens from patients after radiotherapy: should pathology evaluation alter treatment decisions?
  Human pathology 2006 Tihan T, Barletta J, Parney I, Lamborn K, Sneed PK, Chang S
• Survival benefit associated with human anti-mouse antibody (HAMA) in patients with B-cell malignancies.
  Cancer immunology, immunotherapy : CII 2006 Azinovic I, DeNardo GL, Lamborn KR, Mirick G, Goldstein D, Bradt BM, DeNardo SJ
• The role of up-front radiation therapy for incompletely resected pediatric WHO grade II low-grade gliomas.
  Neuro-oncology 2006 Mishra KK, Puri DR, Missett BT, Lamborn KR, Prados MD, Berger MS, Banerjee A, Gupta N, Wara WM, Haas-Kogan DA
• Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme.
  Genes, chromosomes & cancer 2006 Misra A, Pellarin M, Hu L, Kunwar S, Perhouse M, Lamborn KR, Deen DF, Feuerstein BG
• Diagnostic, treatment, and demographic factors influencing survival in a population-based study of adult glioma patients in the San Francisco Bay Area.
  Neuro-oncology 2006 Wrensch M, Rice T, Miike R, McMillan A, Lamborn KR, Aldape K, Prados MD
• Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
  Neuro-oncology 2006 Prados MD, Lamborn KR, Chang S, Burton E, Butowski N, Malec M, Kapadia A, Rabbitt J, Page MS, Fedoroff A, Xie D, Kelley SK
• Implantation of different malignant human cell lines in an athymic mouse does not alter success and growth rates of either xenograft.
  Cancer biotherapy & radiopharmaceuticals 2005 Miers L, DeNardo SJ, Lamborn K, DeNardo GL
• Bromophenol blue staining of tumors in a rat glioma model.
  Neurosurgery 2005 Ozawa T, Britz GW, Kinder DH, Spence AM, VandenBerg S, Lamborn KR, Deen DF, Berger MS
• Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Lassman AB, Rossi MR, Raizer JJ, Razier JR, Abrey LE, Lieberman FS, Grefe CN, Lamborn K, Pao W, Shih AH, Kuhn JG, Wilson R, Nowak NJ, Cowell JK, DeAngelis LM, Wen P, Gilbert MR, Chang S, Yung WA, …
• A design of phase II cancer trials using total and complete response endpoints.
  Statistics in medicine 2005 Lu Y, Jin H, Lamborn KR
• Biomarkers to predict response to epidermal growth factor receptor inhibitors.
  Cell cycle (Georgetown, Tex.) 2005 Haas-Kogan DA, Prados MD, Lamborn KR, Tihan T, Berger MS, Stokoe D
• Does paclitaxel (Taxol) given after (111)In-labeled monoclonal antibodies increase tumor-cumulated activity in epithelial cancers?
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Miers L, Lamborn K, Yuan A, Richman C, Natarajan A, DeNardo S, DeNardo G
• GNOSIS: guidelines for neuro-oncology: standards for investigational studies-reporting of phase 1 and phase 2 clinical trials.
  Neuro-oncology 2005 Chang SM, Reynolds SL, Butowski N, Lamborn KR, Buckner JC, Kaplan RS, Bigner DD
• Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Cloughesy TF, Kuhn J, Robins HI, Abrey L, Wen P, Fink K, Lieberman FS, Mehta M, Chang S, Yung A, DeAngelis L, Schiff D, Junck L, Groves M, Paquette S, Wright J, Lamborn K, Sebti SM, Prados M
• Toxicity, biodistribution, and convection-enhanced delivery of the boronated porphyrin BOPP in the 9L intracerebral rat glioma model.
  International journal of radiation oncology, biology, physics 2005 Ozawa T, Afzal J, Lamborn KR, Bollen AW, Bauer WF, Koo MS, Kahl SB, Deen DF
• High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Richman CM, Denardo SJ, O'Donnell RT, Yuan A, Shen S, Goldstein DS, Tuscano JM, Wun T, Chew HK, Lara PN, Kukis DL, Natarajan A, Meares CF, Lamborn KR, DeNardo GL
• Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.
  Investigational new drugs 2005 Chang SM, Wen P, Cloughesy T, Greenberg H, Schiff D, Conrad C, Fink K, Robins HI, De Angelis L, Raizer J, Hess K, Aldape K, Lamborn KR, Kuhn J, Dancey J, Prados MD, North American Brain Tumor …
• High failure rate in spinal ependymomas with long-term follow-up.
  Neuro-oncology 2005 Gomez DR, Missett BT, Wara WM, Lamborn KR, Prados MD, Chang S, Berger MS, Haas-Kogan DA
• Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.
  Journal of the National Cancer Institute 2005 Haas-Kogan DA, Prados MD, Tihan T, Eberhard DA, Jelluma N, Arvold ND, Baumber R, Lamborn KR, Kapadia A, Malec M, Berger MS, Stokoe D
• Hypoxia-induced BAX overexpression and radiation killing of hypoxic glioblastoma cells.
  Radiation research 2005 Chen JK, Hu LJ, Wang J, Lamborn KR, Kong EL, Deen DF
• Changes in transcranial motor evoked potentials during intramedullary spinal cord tumor resection correlate with postoperative motor function.
  Neurosurgery 2005 Quiñones-Hinojosa A, Lyon R, Zada G, Lamborn KR, Gupta N, Parsa AT, McDermott MW, Weinstein PR
• Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model.
  Cancer gene therapy 2005 Ozawa T, Hu JL, Hu LJ, Kong EL, Bollen AW, Lamborn KR, Deen DF
• Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein BG
• Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Liang Y, Diehn M, Watson N, Bollen AW, Aldape KD, Nicholas MK, Lamborn KR, Berger MS, Botstein D, Brown PO, Israel MA
• A phase II study of concurrent temozolomide and cis-retinoic acid with radiation for adult patients with newly diagnosed supratentorial glioblastoma.
  International journal of radiation oncology, biology, physics 2005 Butowski N, Prados MD, Lamborn KR, Larson DA, Sneed PK, Wara WM, Malec M, Rabbitt J, Page M, Chang SM
• Prognostic significance of intracranial dissemination of glioblastoma multiforme in adults.
  Journal of neurosurgery 2005 Parsa AT, Wachhorst S, Lamborn KR, Prados MD, McDermott MW, Berger MS, Chang SM
• Development of a hypoxia-inducible cytosine deaminase expression vector for gene-directed prodrug cancer therapy.
  Cancer gene therapy 2005 Wang D, Ruan H, Hu L, Lamborn KR, Kong EL, Rehemtulla A, Deen DF
• Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results.
  The Journal of clinical endocrinology and metabolism 2004 Hammer GD, Tyrrell JB, Lamborn KR, Applebury CB, Hannegan ET, Bell S, Rahl R, Lu A, Wilson CB
• Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 2004 Chang SM, Lamborn KR, Malec M, Larson D, Wara W, Sneed P, Rabbitt J, Page M, Nicholas MK, Prados MD
• In vivo evaluation of the boronated porphyrin TABP-1 in U-87 MG intracerebral human glioblastoma xenografts.
  Molecular pharmaceutics 2004 Ozawa T, Santos RA, Lamborn KR, Bauer WF, Koo MS, Kahl SB, Deen DF
• Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
  Neuro-oncology 2004 Ozawa T, Gryaznov SM, Hu LJ, Pongracz K, Santos RA, Bollen AW, Lamborn KR, Deen DF
• Prognostic factors for survival of patients with glioblastoma: recursive partitioning analysis.
  Neuro-oncology 2004 Lamborn KR, Chang SM, Prados MD
• Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome.
  Neurosurgery 2004 Papavassiliou E, Rau G, Heath S, Abosch A, Barbaro NM, Larson PS, Lamborn K, Starr PA
• Permanent iodine 125 brachytherapy in patients with progressive or recurrent glioblastoma multiforme.
  Neuro-oncology 2004 Larson DA, Suplica JM, Chang SM, Lamborn KR, McDermott MW, Sneed PK, Prados MD, Wara WM, Nicholas MK, Berger MS
• Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients.
  Journal of neurosurgery 2004 Keles GE, Lundin DA, Lamborn KR, Chang EF, Ojemann G, Berger MS
• Temozolomide in the treatment of recurrent malignant glioma.
  Cancer 2004 Chang SM, Theodosopoulos P, Lamborn K, Malec M, Rabbitt J, Page M, Prados MD
• Volume of residual disease as a predictor of outcome in adult patients with recurrent supratentorial glioblastomas multiforme who are undergoing chemotherapy.
  Journal of neurosurgery 2004 Keles GE, Lamborn KR, Chang SM, Prados MD, Berger MS
• Incidence of venous thromboembolism in patients undergoing craniotomy and motor mapping for glioma without intraoperative mechanical prophylaxis to the contralateral leg.
  Journal of neurosurgery 2003 Auguste KI, Quinones-Hinojosa A, Gadkary C, Zada G, Lamborn KR, Berger MS
• Characterization of human IgG antimouse antibody in patients with B-cell malignancies.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 DeNardo GL, Mirick GR, Kroger LA, Bradt BM, Lamborn KR, DeNardo SJ
• Coregistration accuracy and detection of brain shift using intraoperative sononavigation during resection of hemispheric tumors.
  Neurosurgery 2003 Keles GE, Lamborn KR, Berger MS
• Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 DeNardo SJ, Yao Z, Lam KS, Song A, Burke PA, Mirick GR, Lamborn KR, O'Donnell RT, DeNardo GL
• Enhanced therapeutic index of radioimmunotherapy (RIT) in prostate cancer patients: comparison of radiation dosimetry for 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)-peptide versus 2IT-DOTA monoclonal antibody linkage for RIT.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 DeNardo SJ, DeNardo GL, Yuan A, Richman CM, O'Donnell RT, Lara PN, Kukis DL, Natarajan A, Lamborn KR, Jacobs F, Siantar CL
• Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 DeNardo GL, DeNardo SJ, Peterson JJ, Miers LA, Lam KS, Hartmann-Siantar C, Lamborn KR
• Selection and characterization of anti-MUC-1 scFvs intended for targeted therapy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Winthrop MD, DeNardo SJ, Albrecht H, Mirick GR, Kroger LA, Lamborn KR, Venclovas C, Colvin ME, Burke PA, DeNardo GL
• Gliomatosis cerebri: a review of 22 cases.
  Neurosurgery 2003 Vates GE, Chang S, Lamborn KR, Prados M, Berger MS
• Detection of hypoxia in human brain tumor xenografts using a modified comet assay.
  Neoplasia (New York, N.Y.) 2003 Wang J, Klem J, Wyrick JB, Ozawa T, Cunningham E, Golinveaux J, Allen MJ, Lamborn KR, Deen DF
• Radiation therapy for intracranial germ cell tumors.
  International journal of radiation oncology, biology, physics 2003 Haas-Kogan DA, Missett BT, Wara WM, Donaldson SS, Lamborn KR, Prados MD, Fisher PG, Huhn SL, Fisch BM, Berger MS, Le QT
• Repeated operations for infiltrative low-grade gliomas without intervening therapy.
  Journal of neurosurgery 2003 Schmidt MH, Berger MS, Lamborn KR, Aldape K, McDermott MW, Prados MD, Chang SM
• Grade II astrocytomas are subgrouped by chromosome aberrations.
  Cancer genetics and cytogenetics 2003 Hirose Y, Aldape KD, Chang S, Lamborn K, Berger MS, Feuerstein BG
• Anti-CD22 ligand-blocking antibody HB22.7 has independent lymphomacidal properties and augments the efficacy of 90Y-DOTA-peptide-Lym-1 in lymphoma xenografts.
  Blood 2003 Tuscano JM, O'Donnell RT, Miers LA, Kroger LA, Kukis DL, Lamborn KR, Tedder TF, DeNardo GL
• Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma.
  International journal of radiation oncology, biology, physics 2002 Larson DA, Prados M, Lamborn KR, Smith V, Sneed PK, Chang S, Nicholas KM, Wara WM, Devriendt D, Kunwar S, Berger M, McDermott MW
• Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma.
  Cancer research 2002 Burton EC, Lamborn KR, Feuerstein BG, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD
• Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors.
  Nature genetics 2002 Zardo G, Tiirikainen MI, Hong C, Misra A, Feuerstein BG, Volik S, Collins CC, Lamborn KR, Bollen A, Pinkel D, Albertson DG, Costello JF
• Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts.
  Cancer research 2002 Burke PA, DeNardo SJ, Miers LA, Lamborn KR, Matzku S, DeNardo GL
• Predictive model for pain recurrence after posterior fossa surgery for trigeminal neuralgia.
  Archives of neurology 2002 Theodosopoulos PV, Marco E, Applebury C, Lamborn KR, Wilson CB
• VAMP and low-dose, involved-field radiation for children and adolescents with favorable, early-stage Hodgkin's disease: results of a prospective clinical trial.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002 Donaldson SS, Hudson MM, Lamborn KR, Link MP, Kun L, Billett AL, Marcus KC, Hurwitz CA, Young JA, Tarbell NJ, Weinstein HJ
• Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas.
  Neuro-oncology 2002 Kuriyama H, Lamborn KR, O'Fallon JR, Iturria N, Sebo T, Schaefer PL, Scheithauer BW, Buckner JC, Kuriyama N, Jenkins RB, Israel MA
• Delayed surgical resection reduces intraoperative blood loss for embolized meningiomas.
  Neurosurgery 2002 Chun JY, McDermott MW, Lamborn KR, Wilson CB, Higashida R, Berger MS
• Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2002 Ermoian RP, Furniss CS, Lamborn KR, Basila D, Berger MS, Gottschalk AR, Nicholas MK, Stokoe D, Haas-Kogan DA
• Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2002 Burton EC, Lamborn KR, Forsyth P, Scott J, O'Campo J, Uyehara-Lock J, Prados M, Berger M, Passe S, Uhm J, O'Neill BP, Jenkins RB, Aldape KD
• Combined modality radioimmunotherapy for human prostate cancer xenografts with taxanes and 90yttrium-DOTA-peptide-ChL6.
  The Prostate 2002 O'Donnell RT, DeNardo SJ, Miers LA, Lamborn KR, Kukis DL, DeNardo GL, Meyers FJ
• Growth of human glioblastomas as xenografts in the brains of athymic rats.
  In vivo (Athens, Greece) 2002 Ozawa T, Wang J, Hu LJ, Bollen AW, Lamborn KR, Deen DF
• Dose conformity of gamma knife radiosurgery and risk factors for complications.
  International journal of radiation oncology, biology, physics 2001 Nakamura JL, Verhey LJ, Smith V, Petti PL, Lamborn KR, Larson DA, Wara WM, McDermott MW, Sneed PK
• Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcome.
  Journal of neurosurgery 2001 Keles GE, Lamborn KR, Berger MS
• Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival.
  Cancer research 2001 Kunwar S, Mohapatra G, Bollen A, Lamborn KR, Prados M, Feuerstein BG
• A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy.
  Neoplasia (New York, N.Y.) 2001 Ruan H, Su H, Hu L, Lamborn KR, Kan YW, Deen DF
• Relationship between pattern of enhancement and local control of brain metastases after radiosurgery.
  International journal of radiation oncology, biology, physics 2001 Goodman KA, Sneed PK, McDermott MW, Shiau CY, Lamborn KR, Chang S, Park E, Wara WM, Larson DA
• Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
  Cancer research 2001 Kuriyama N, Kuriyama H, Julin CM, Lamborn KR, Israel MA
• Radiosurgery for brain metastases from primary lung carcinoma.
  Cancer journal (Sudbury, Mass.) 2001 Hoffman R, Sneed PK, McDermott MW, Chang S, Lamborn KR, Park E, Wara WM, Larson DA
• Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients.
  Cancer research 2001 Simmons ML, Lamborn KR, Takahashi M, Chen P, Israel MA, Berger MS, Godfrey T, Nigro J, Prados M, Chang S, Barker FG, Aldape K
• Efficacy and toxicity of radioimmunotherapy with (90)Y-DOTA-peptide-ChL6 for PC3-tumored mice.
  The Prostate 2000 O'Donnell RT, DeNardo SJ, DeNardo GL, Miers L, Lamborn KR, Kukis DL, Meyers FJ
• Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy.
  Cancer biotherapy & radiopharmaceuticals 2000 DeNardo SJ, Burke PA, Leigh BR, O'Donnell RT, Miers LA, Kroger LA, Goodman SL, Matzku S, Jonczyk A, Lamborn KR, DeNardo GL
• A clinical trial of radioimmunotherapy with 67Cu-2IT-BAT-Lym-1 for non-Hodgkin's lymphoma.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999 O'Donnell RT, DeNardo GL, Kukis DL, Lamborn KR, Shen S, Yuan A, Goldstein DS, Carr CE, Mirick GR, DeNardo SJ
• Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX.
  Neoplasia (New York, N.Y.) 1999 Ruan H, Wang J, Hu L, Lin CS, Lamborn KR, Deen DF
• Long-term impairment of subependymal repopulation following damage by ionizing irradiation.
  Experimental neurology 1999 Tada E, Yang C, Gobbel GT, Lamborn KR, Fike JR
• 67Copper-2-iminothiolane-6-[p-(bromoacetamido)benzyl-TETA-Lym-1 for radioimmunotherapy of non-Hodgkin's lymphoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 1999 O'Donnell RT, DeNardo GL, Kukis DL, Lamborn KR, Shen S, Yuan A, Goldstein DS, Mirick GR, DeNardo SJ
• Radiopotentiation of human brain tumor cells by sodium phenylacetate.
  Cancer letters 1999 Ozawa T, Lu RM, Hu LJ, Lamborn KR, Prados MD, Deen DF
• Critical Lym-1 binding residues on polymorphic HLA-DR molecules.
  Molecular immunology 1999 Rose LM, Deng CT, Scott SL, Xiong CY, Lamborn KR, Gumerlock PH, DeNardo GL, Meares CF
• Factors affecting 131I-Lym-1 pharmacokinetics and radiation dosimetry in patients with non-Hodgkin's lymphoma and chronic lymphocytic leukemia.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999 DeNardo GL, DeNardo SJ, Shen S, DeNardo DA, Mirick GR, Macey DJ, Lamborn KR
• Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors.
  Cancer 1999 Russo C, Pellarin M, Tingby O, Bollen AW, Lamborn KR, Mohapatra G, Collins VP, Feuerstein BG
• Radiation-induced DNA double-strand breaks and rejoining in malignant glioma cells.
  International journal of radiation biology 1999 Ozawa T, Wang J, Lamborn KR, Deen DF
• Toxicology of a boronated porphyrin in dogs.
  Photochemistry and photobiology 1999 Tibbitts J, Fike JR, Lamborn KR, Bollen AW, Kahl SB
• Final report on the University of California-San Francisco experience with bromodeoxyuridine labeling index as a prognostic factor for the survival of glioma patients.
  Cancer 1999 Lamborn KR, Prados MD, Kaplan SB, Davis RL
• Radiosurgery for brain metastases: is whole brain radiotherapy necessary?
  International journal of radiation oncology, biology, physics 1999 Sneed PK, Lamborn KR, Forstner JM, McDermott MW, Chang S, Park E, Gutin PH, Phillips TL, Wara WM, Larson DA
• Transsphenoidal microsurgical therapy of prolactinomas: initial outcomes and long-term results.
  Neurosurgery 1999 Tyrrell JB, Lamborn KR, Hannegan LT, Applebury CB, Wilson CB
• Synergistic therapy of breast cancer with Y-90-chimeric L6 and paclitaxel in the xenografted mouse model: development of a clinical protocol.
  Anticancer research 1998 Denardo SJ, Richman CM, Kukis DL, Shen S, Lamborn KR, Miers LA, Kroger LA, Perez EA, Denardo GL
• Tumor cell apoptosis present at diagnosis may predict treatment outcome for patients with medulloblastoma.
  Journal of pediatric hematology/oncology 1998 Haslam RH, Lamborn KR, Becker LE, Israel MA
• Comparison of 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid (DOTA)-peptide-ChL6, a novel immunoconjugate with catabolizable linker, to 2-iminothiolane-2-[p-(bromoacetamido)benzyl]-DOTA-ChL6 in breast cancer xenografts.
  Clinical cancer research : an official journal of the American Association for Cancer Research 1998 DeNardo GL, Kroger LA, Meares CF, Richman CM, Salako Q, Shen S, Lamborn KR, Peterson JJ, Miers LA, Zhong GR, DeNardo SJ
• Maximum-tolerated dose, toxicity, and efficacy of (131)I-Lym-1 antibody for fractionated radioimmunotherapy of non-Hodgkin's lymphoma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 DeNardo GL, DeNardo SJ, Goldstein DS, Kroger LA, Lamborn KR, Levy NB, McGahan JP, Salako Q, Shen S, Lewis JP
• Transsphenoidal microsurgery for growth hormone-secreting pituitary adenomas: initial outcome and long-term results.
  The Journal of clinical endocrinology and metabolism 1998 Abosch A, Tyrrell JB, Lamborn KR, Hannegan LT, Applebury CB, Wilson CB
• Low-dose, fractionated radioimmunotherapy for B-cell malignancies using 131I-Lym-1 antibody.
  Cancer biotherapy & radiopharmaceuticals 1998 DeNardo GL, DeNardo SJ, Lamborn KR, Goldstein DS, Levy NB, Lewis JP, O'Grady LF, Raventos A, Kroger LA, Macey DJ, McGahan JP, Mills SL, Shen S
• Characterization of human glioblastoma xenograft growth in athymic mice.
  In vivo (Athens, Greece) 1998 Ozawa T, Wang J, Hu LJ, Lamborn KR, Bollen AW, Deen DF
• Cerebrovascular effects of the bradykinin analog RMP-7 in normal and irradiated dog brain.
  Journal of neuro-oncology 1998 Fike JR, Gobbel GT, Mesiwala AH, Shin HJ, Nakagawa M, Lamborn KR, Seilhan TM, Elliott PJ
• Quantification of iodine-131 in tumors using a threshold based on image contrast.
  European journal of nuclear medicine 1998 DeNardo GL, Shen S, DeNardo SJ, Liao SQ, Lamborn KR, DeNardo DA, Yuan A
• Yttrium-90-DOTA-peptide-chimeric L6 radioimmunoconjugate: efficacy and toxicity in mice bearing p53 mutant human breast cancer xenografts.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998 DeNardo SJ, Kukis DL, Miers LA, Winthrop MD, Kroger LA, Salako Q, Shen S, Lamborn KR, Gumerlock PH, Meares CF, DeNardo GL
• Second cancers following pediatric Hodgkin's disease.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Wolden SL, Lamborn KR, Cleary SF, Tate DJ, Donaldson SS
• Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 1998 Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH
• Radiation in pediatric Hodgkin's disease.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Donaldson SS, Lamborn KR
• Enhancement of 67Cu-2IT-BAT-LYM-1 therapy in mice with human Burkitt's lymphoma (Raji) using interleukin-2.
  Cancer 1997 DeNardo GL, Kukis DL, DeNardo SJ, Shen S, Mausner LF, O'Donnell RT, Lamborn KR, Meyers FJ, Srivastava SC, Miers LA
• Importance of temporal relationships in combined modality radioimmunotherapy of breast carcinoma.
  Cancer 1997 DeNardo SJ, Kroger LA, Lamborn KR, Miers LA, O'Donnell RT, Kukis DL, Richman CM, DeNardo GL
• Increased survival associated with radiolabeled Lym-1 therapy for non-Hodgkin's lymphoma and chronic lymphocytic leukemia.
  Cancer 1997 DeNardo GL, Lamborn KR, Goldstein DS, Kroger LA, DeNardo SJ
• Treatment-related parameters predicting efficacy of Lym-1 radioimmunotherapy in patients with B-lymphocytic malignancies.
  Clinical cancer research : an official journal of the American Association for Cancer Research 1997 Lamborn KR, DeNardo GL, DeNardo SJ, Goldstein DS, Shen S, Larkin EC, Kroger LA
• Adult medulloblastoma: an analysis of survival and prognostic factors.
  The cancer journal from Scientific American 1997 Le QT, Weil MD, Wara WM, Lamborn KR, Prados MD, Edwards MS, Gutin PH
• Apoptosis in the subependyma of young adult rats after single and fractionated doses of X-rays.
  Cancer research 1997 Shinohara C, Gobbel GT, Lamborn KR, Tada E, Fike JR
• Effects of Matrigel on the SF-767 malignant glioma athymic mouse tumor model.
  Anticancer research 1997 Wyrick BJ, Ozawa T, Lamborn KR, Bollen AW, Deen DF
• Radioimmunotherapy for advanced breast cancer using I-131-ChL6 antibody.
  Anticancer research 1997 Denardo SJ, O'Grady LF, Richman CM, Goldstein DS, O'Donnell RT, Denardo DA, Kroger LA, Lamborn KR, Hellström KE, Hellström I, Denardo GL
• Synergy of Taxol and radioimmunotherapy with yttrium-90-labeled chimeric L6 antibody: efficacy and toxicity in breast cancer xenografts.
  Proceedings of the National Academy of Sciences of the United States of America 1997 DeNardo SJ, Kukis DL, Kroger LA, O'Donnell RT, Lamborn KR, Miers LA, DeNardo DG, Meares CF, DeNardo GL
• Radiosurgery for brain metastases: relationship of dose and pattern of enhancement to local control.
  International journal of radiation oncology, biology, physics 1997 Shiau CY, Sneed PK, Shu HK, Lamborn KR, McDermott MW, Chang S, Nowak P, Petti PL, Smith V, Verhey LJ, Ho M, Park E, Wara WM, Gutin PH, Larson DA
• Reproducibility of operator processing for radiation dosimetry.
  Nuclear medicine and biology 1997 Shen S, DeNardo GL, DeNardo SJ, Yuan A, DeNardo DA, Lamborn KR
• Prediction of radiation doses from therapy using tracer studies with iodine-131-labeled antibodies.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996 DeNardo DA, DeNardo GL, Yuan A, Shen S, DeNardo SJ, Macey DJ, Lamborn KR, Mahe M, Groch MW, Erwin WD
• Factors influencing survival after gamma knife radiosurgery for patients with single and multiple brain metastases.
  The cancer journal from Scientific American 1996 Shu HK, Sneed PK, Shiau CY, McDermott MW, Lamborn KR, Park E, Ho M, Petti PL, Smith V, Verhey LJ, Wara WM, Gutin PH, Larson DA
• Microglial responses after focal radiation-induced injury are affected by alpha-difluoromethylornithine.
  International journal of radiation oncology, biology, physics 1996 Nakagawa M, Bellinzona M, Seilhan TM, Gobbel GT, Lamborn KR, Fike JR
• Long-term follow-up after high-activity 125I brachytherapy for pediatric brain tumors.
  Pediatric neurosurgery 1996 Sneed PK, Russo C, Scharfen CO, Prados MD, Malec MK, Larson DA, Lamborn KR, Lamb SA, Voss B, Weaver KA, Phillips TL, Gutin PH, Wara WM, Edwards MS
• Demonstration of brachytherapy boost dose-response relationships in glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 1996 Sneed PK, Lamborn KR, Larson DA, Prados MD, Malec MK, McDermott MW, Weaver KA, Phillips TL, Wara WM, Gutin PH
• Bromodeoxyuridine labeling index in glioblastoma multiforme: relation to radiation response, age, and survival.
  International journal of radiation oncology, biology, physics 1996 Barker FG, Prados MD, Chang SM, Davis RL, Gutin PH, Lamborn KR, Larson DA, McDermott MW, Sneed PK, Wilson CB
• Radiation response and survival time in patients with glioblastoma multiforme.
  Journal of neurosurgery 1996 Barker FG, Prados MD, Chang SM, Gutin PH, Lamborn KR, Larson DA, Malec MK, McDermott MW, Sneed PK, Wara WM, Wilson CB
• Prognostic factors for radioimmunotherapy in patients with B-lymphocytic malignancies.
  Cancer research 1995 DeNardo GL, Lamborn KR, DeNardo SJ, Goldstein DS, Dolber-Smith EG, Kroger LA, Larkin EC, Shen S
• Yttrium-90 chimeric L6 therapy of human breast cancer in nude mice and apoptosis-related messenger RNA expression.
  Cancer research 1995 DeNardo SJ, Gumerlock PH, Winthrop MD, Mack PC, Chi SG, Lamborn KR, Shen S, Miers LA, deVere White RW, DeNardo GL
• Large effect of age on the survival of patients with glioblastoma treated with radiotherapy and brachytherapy boost.
  Neurosurgery 1995 Sneed PK, Prados MD, McDermott MW, Larson DA, Malec MK, Lamborn KR, Davis RL, Weaver KA, Wara WM, Phillips TL
• Analysis of antiglobulin (HAMA) response in a group of patients with B-lymphocytic malignancies treated with 131I-Lym-1.
  The International journal of biological markers 1995 De Nardo GL, Kroger LA, Mirick GR, Lamborn KR, De Nardo SJ
• The biologic window for chimeric L6 radioimmunotherapy.
  Cancer 1994 DeNardo SJ, Mirick GR, Kroger LA, O'Grady LF, Erickson KL, Yuan A, Lamborn KR, Hellstrom I, Hellstrom KE, DeNardo GL
• Use of response surface statistical designs to detect effects of biologic response modifiers such as IL-2.
  Biotechnology therapeutics 1994 DeNardo GL, Lamborn KR, DeNardo SJ, Kroger LA
• High activity iodine-125 interstitial implant for gliomas.
  International journal of radiation oncology, biology, physics 1992 Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Prados MD, Weaver KA, Malec M, Acord P, Lamborn KR
• Quantitative imaging of mouse L-6 monoclonal antibody in breast cancer patients to develop a therapeutic strategy.
  International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991 DeNardo SJ, O'Grady LF, Macey DJ, Kroger LA, DeNardo GL, Lamborn KR, Levy NB, Mills SL, Hellstrom I, Hellstrom KE
• Trimetrexate in locally advanced or metastatic adenocarcinoma of the pancreas. A phase II study of the Northern California Oncology Group.
  Investigational new drugs 1990 Carlson RW, Doroshow JH, Odujinrin OO, Flam MS, Malec M, Lamborn KR