Karuna Subramaniam, PhD
Associate Professor
Psychiatry
School of Medicine

Grants and Projects

Show all (2) Hide

• Causal Role of Medial Prefrontal Neural Activity in Self-Agency in Schizophrenia, NIH, 2020-2025
• Neural Impact of Positive Mood on Motivation and Reward Networks in Schizophrenia, NIH, 2014-2021

Publications (42)

Top publication keywords:
Memory, Short-TermMemoryAnticipation, PsychologicalCognition DisordersBrain MappingMetaphorPsychotic DisordersSchizophrenic PsychologyMental RecallPrefrontal CortexTinnitusBeta RhythmSpeechAffectSchizophrenia

• A randomised controlled trial investigating the causal role of the medial prefrontal cortex in mediating self-agency during speech monitoring and reality monitoring.
  Scientific reports 2024 Tan S, Jia Y, Jariwala N, Zhang Z, Brent K, Houde J, Nagarajan S, Subramaniam K
• Causal role of medial superior frontal cortex on enhancing neural information flow and self-agency judgments in the self-agency network.
  medRxiv : the preprint server for health sciences 2024 Jia Y, Kudo K, Jariwala N, Tarapore P, Nagarajan S, Subramaniam K
• A randomised controlled trial investigating the causal role of the medial prefrontal cortex in mediating self-agency during speech monitoring and reality monitoring.
  Research square 2023 Tan S, Jia Y, Jariwala N, Zhang Z, Brent K, Houde J, Nagarajan S, Subramaniam K
• Reduced neural connectivity in the caudate anterior head predicts hallucination severity in schizophrenia.
  Schizophrenia research 2023 Hinkley LBN, Haas SS, Cheung SW, Nagarajan SS, Subramaniam K
• Abnormal resting-state functional connectivity underlies cognitive and clinical symptoms in patients with schizophrenia.
  Frontiers in human neuroscience 2023 Jia Y, Jariwala N, Hinkley LBN, Nagarajan S, Subramaniam K

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• Abnormal Information Flow in Schizophrenia Is Linked to Psychosis.
  Schizophrenia bulletin 2022 Jia Y, Kudo K, Hinkley LBN, Fisher M, Vinogradov S, Nagarajan S, Subramaniam K
• The Role of the Medial Prefontal Cortex in Self-Agency in Schizophrenia.
  Journal of psychiatry and brain science 2021 Subramaniam K
• Author Correction: Multivariate pattern analysis of brain structure predicts functional outcome after auditory-based cognitive training interventions.
  NPJ schizophrenia 2021 Kambeitz-Ilankovic L, Vinogradov S, Wenzel J, Fisher M, Haas SS, Betz L, Penzel N, Nagarajan S, Koutsouleris N, Subramaniam K
• Multivariate pattern analysis of brain structure predicts functional outcome after auditory-based cognitive training interventions.
  NPJ schizophrenia 2021 Kambeitz-Ilankovic L, Vinogradov S, Wenzel J, Fisher M, Haas SS, Betz L, Penzel N, Nagarajan S, Koutsouleris N, Subramaniam K
• A Neural Biomarker for Hallucinations: Medial Prefrontal Aberrations in Neural Connectivity Predict Self-Agency Deficits and Hallucination Severity in Schizophrenia.
  Journal of brain research 2021 Haas SS, Hinkley LBN, Fisher M, Vinogradov S, Nagarajan S, Subramaniam K
• The Visual Word Form Area compensates for auditory working memory dysfunction in schizophrenia.
  Scientific reports 2020 Herman AB, Brown EG, Dale CL, Hinkley LB, Subramaniam K, Houde JF, Fisher M, Vinogradov S, Nagarajan SS
• Establishing a Causal Role for Medial Prefrontal Cortex in Reality Monitoring.
  Frontiers in human neuroscience 2020 Subramaniam K, Kothare H, Hinkley LB, Tarapore P, Nagarajan SS
• Intervention-specific patterns of cortical function plasticity during auditory encoding in people with schizophrenia.
  Schizophrenia research 2019 Dale CL, Brown EG, Herman AB, Hinkley LBN, Subramaniam K, Fisher M, Vinogradov S, Nagarajan SS
• Multi-outcome meta-analysis (MOMA) of cognitive remediation in schizophrenia: Revisiting the relevance of human coaching and elucidating interplay between multiple outcomes.
  Neuroscience and biobehavioral reviews 2019 Kambeitz-Ilankovic L, Betz LT, Dominke C, Haas SS, Subramaniam K, Fisher M, Vinogradov S, Koutsouleris N, Kambeitz J
• Beta-band activity in medial prefrontal cortex predicts source memory encoding and retrieval accuracy.
  Scientific reports 2019 Subramaniam K, Hinkley LBN, Mizuiri D, Kothare H, Cai C, Garrett C, Findlay A, Houde JF, Nagarajan SS
• 145. Social Cognitive Training Enhances Neural Activation Patterns Associated With Reward Processing in Schizophrenia.
  Biological Psychiatry 2019 Karuna Subramaniam, Bruno Biagianti, Christine Hooker, Melissa Fisher, Srikantan Nagarjan, Sophia Vinogradov
• 5.3 SOCIAL COGNITIVE TRAINING IMPROVES MOTIVATION TO EARN REWARDING OUTCOMES IN PSYCHOSIS.
  Schizophrenia Bulletin 2019 Karuna Subramaniam, Bruno Biagianti, Christine Hooker, Melissa Fisher, Srikantan Nagarajan, Sophia Vinogradov
• 5.4 INDIVIDUALIZED PREDICTION OF FUNCTIONAL OUTCOMES IN SCHIZOPHRENIA PATIENTS IN RESPONSE TO NEURO-COGNITIVE INTERVENTION: A MACHINE LEARNING ANALYSIS.
  Schizophrenia Bulletin 2019 Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris, Julian Wenzel, Shalaila Haas, Melissa Fisher, Sophia Vinogradov, Karuna Subramaniam
• Functional and Structural Brain Plasticity in Adult Onset Single-Sided Deafness.
  Frontiers in human neuroscience 2018 Shang Y, Hinkley LB, Cai C, Subramaniam K, Chang YS, Owen JP, Garrett C, Mizuiri D, Mukherjee P, Nagarajan SS, Cheung SW
• F149. NEUROBIOLOGY OF SELF-AGENCY DURING REALITY MONITORING AND SPEECH FEEDBACK MONITORING: IMPLICATIONS FOR TREATMENT DEVELOPMENT IN SCHIZOPHRENIA.
  Schizophrenia Bulletin 2018 Karuna Subramaniam, Leighton Hinkley, Hardik Kothare, Danielle Mizuiri, Sophia Vinogradov, John Houde, Srikantan Nagarajan
• Reality Monitoring and Feedback Control of Speech Production Are Related Through Self-Agency.
  Frontiers in human neuroscience 2018 Subramaniam K, Kothare H, Mizuiri D, Nagarajan SS, Houde JF
• White matter microstructure predicts cognitive training-induced improvements in attention and executive functioning in schizophrenia.
  Schizophrenia research 2017 Subramaniam K, Gill J, Fisher M, Mukherjee P, Nagarajan S, Vinogradov S
• Neural mechanisms of mood-induced modulation of reality monitoring in schizophrenia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2017 Subramaniam K, Ranasinghe KG, Mathalon D, Nagarajan S, Vinogradov S
• Neural Mechanisms of Positive Mood Induced Modulation of Reality Monitoring.
  Frontiers in human neuroscience 2016 Subramaniam K, Gill J, Slattery P, Shastri A, Mathalon DH, Nagarajan S, Vinogradov S
• Neural signal during immediate reward anticipation in schizophrenia: Relationship to real-world motivation and function.
  NeuroImage. Clinical 2015 Subramaniam K, Hooker CI, Biagianti B, Fisher M, Nagarajan S, Vinogradov S
• Auditory Cortical Plasticity Drives Training-Induced Cognitive Changes in Schizophrenia.
  Schizophrenia bulletin 2015 Dale CL, Brown EG, Fisher M, Herman AB, Dowling AF, Hinkley LB, Subramaniam K, Nagarajan SS, Vinogradov S
• Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains.
  NeuroImage 2014 Subramaniam K, Luks TL, Garrett C, Chung C, Fisher M, Nagarajan S, Vinogradov S
• BEHAVIORAL AND NEURAL SYSTEM EFFECTS OF COMPUTERIZED SOCIAL COGNITIVE TRAINING EXERCISES IN SCHIZOPHRENIA.
  Schizophrenia Research 2014 Sophia Vinogradov, Mor Nahum, Karuna Subramaniam, Melissa Fisher, Christine Hooker
• COMBINING COGNITIVE AND SOCIAL COGNITIVE TRAINING FOR INDIVIDUALS WITH SCHIZOPHRENIA.
  Schizophrenia Research 2014 Sophia Vinogradov, Karuna Subramaniam, Bruno Biagianti, Christine Hooker, Melissa Fisher
• Improving the neural mechanisms of cognition through the pursuit of happiness.
  Frontiers in human neuroscience 2013 Subramaniam K, Vinogradov S
• Positively valenced stimuli facilitate creative novel metaphoric processes by enhancing medial prefrontal cortical activation.
  Frontiers in psychology 2013 Subramaniam K, Beeman M, Faust M, Mashal N
• Cognitive training for psychiatric disorders.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013 Subramaniam K, Vinogradov S
• Computerized cognitive training in schizophrenia: current knowledge and future directions.
  Cognitive Impairment in Schizophrenia 2013 Melissa Fisher, Karuna Subramaniam, Rogerio Panizzutti, Sophia Vinogradov
• The repetition paradigm: enhancement of novel metaphors and suppression of conventional metaphors in the left inferior parietal lobe.
  Neuropsychologia 2012 Subramaniam K, Faust M, Beeman M, Mashal N
• Computerized cognitive training restores neural activity within the reality monitoring network in schizophrenia.
  Neuron 2012 Subramaniam K, Luks TL, Fisher M, Simpson GV, Nagarajan S, Vinogradov S
• NEUROPLASTICITY-BASED COGNITIVE TRAINING IMPROVES REALITY MONITORING IN SCHIZOPHRENIA PATIENTS: BEHAVIORAL AND FMRI ASSESSMENTS.
  Schizophrenia Research 2010 Karuna Subramaniam, Tracy Luks, Stephanie Aldebot, Adelaide Hearst, Arul Thangavel, Melissa Fisher, Gregory V. Simpson, Srikantan Nagarajan, Sophia Vinogradov
• Timing is everything: neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects.
  International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2009 Dale CL, Findlay AM, Adcock RA, Vertinski M, Fisher M, Genevsky A, Aldebot S, Subramaniam K, Luks TL, Simpson GV, Nagarajan SS, Vinogradov S
• Neuroplasticity-based cognitive training improves working-memory and self-referential source-memory in schizophrenia patients: Behavioral and fMRI assessments.
  NeuroImage 2009 K. Subramaniam, T. Luks, S. Aldebot, A. Hearst, A. Thangavel, M. Fisher, M. Vertinski, C. Garrett, G.V. Simpson, S. Nagarajan, S. Vinogradov
• Neuroplasticity-based cognitive training in schizophrenia: an interim report on the effects 6 months later.
  Schizophrenia bulletin 2009 Fisher M, Holland C, Subramaniam K, Vinogradov S
• A brain mechanism for facilitation of insight by positive affect.
  Journal of cognitive neuroscience 2009 Subramaniam K, Kounios J, Parrish TB, Jung-Beeman M
• NEUROPLASTICITY-BASED COGNITIVE TRAINING IMPROVES SELF-REFERENTIAL SOURCE MEMORY COMPARED TO BASELINE PERFORMANCE IN SCHIZOPHRENIA PATIENTS.
  Schizophrenia Research 2008 Karuna Subramaniam, Stephanie Aldebot, Arul Thangavel, Coleman Garrett, Christine Holland, Melissa Fisher, Adelaide Hearst, Tracy Luks, Sophia Vinogradov
• The prepared mind: neural activity prior to problem presentation predicts subsequent solution by sudden insight.
  Psychological science 2006 Kounios J, Frymiare JL, Bowden EM, Fleck JI, Subramaniam K, Parrish TB, Jung-Beeman M