Karthik Srinivasan, PhD
Postdoctoral Scholar
Pharmaceutical Chemistry
School of Pharmacy

Education & Training

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• PhD Structural, Biophysical, and Computational Biology Purdue University 08/2023
• M.Sc. (Hons.) Biological Sciences BITS Pilani 08/2017
• B.E. (Hons.) Mechanical Engineering BITS Pilani 08/2017

Publications (5)

Top publication keywords:
Protein TransportScattering, Small AngleMethyltransferasesUbiquitinsBacterial Outer Membrane ProteinsCatalytic DomainNeisseria gonorrhoeaeViral Nonstructural ProteinsX-Ray DiffractionMiddle East Respiratory Syndrome CoronavirusProtein PrecursorsArabidopsis ProteinsChloroplastsPlant ProteinsArabidopsis

• Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.
  ACS central science 2025 Vigneron SF, Ohno S, Braz J, Kim JY, Kweon OS, Webb C, Billesbølle CB, Srinivasan K, Bhardwaj K, Irwin JJ, Manglik A, Basbaum AI, Ellman JA, Shoichet BK
• Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
  Structure (London, England : 1993) 2023 Srinivasan K, Erramilli SK, Chakravarthy S, Gonzalez A, Kossiakoff A, Noinaj N
• Structure Determination of Membrane Proteins Using X-Ray Crystallography.
  Methods in molecular biology (Clifton, N.J.) 2021 Billings E, Lundquist K, Overly C, Srinivasan K, Noinaj N
• Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues.
  Journal of medicinal chemistry 2020 Chen D, Dong C, Dong G, Srinivasan K, Min J, Noinaj N, Huang R
• Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
  Antiviral research 2019 Clasman JR, Everett RK, Srinivasan K, Mesecar AD