Karl Kumbier, PhD
Data Scientist
Pharmaceutical Chemistry
School of Pharmacy

Publications (9)

Top publication keywords:
Drug DiscoveryMachine LearningPacific OceanBacteriaPhosphorylationLeucine-Rich Repeat Serine-Threonine Protein Kinase-2PhytoplanktonModels, Geneticrab GTP-Binding ProteinsHarmful Algal BloomDrosophilaWater Pollution, ChemicalAlternative SplicingSeawaterChlorophyll

• Epistasis regulates genetic control of cardiac hypertrophy.
  Research square 2023 Wang Q, Tang TM, Youlton N, Weldy CS, Kenney AM, Ronen O, Hughes JW, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Tang WHW, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown …
• Epistasis regulates genetic control of cardiac hypertrophy.
  medRxiv : the preprint server for health sciences 2023 Wang Q, Tang TM, Youlton N, Weldy CS, Kenney AM, Ronen O, Hughes JW, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Tang WHW, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown …
• Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity.
  Cell reports 2023 Rinaldi C, Waters CS, Li Z, Kumbier K, Rao L, Nichols RJ, Jacobson MP, Wu LF, Altschuler SJ
• Selection of Optimal Cell Lines for High-Content Phenotypic Screening.
  ACS chemical biology 2023 Heinrich L, Kumbier K, Li L, Altschuler SJ, Wu LF
• Selection of optimal cell lines for high-content phenotypic screening.
  bioRxiv : the preprint server for biology 2023 Heinrich L, Kumbier K, Li L, Altschuler SP, Wu LF

Show all (4 more) Hide

• A novel random forest approach to revealing interactions and controls on chlorophyll concentration and bacterial communities during coastal phytoplankton blooms.
  Scientific reports 2021 Cheng Y, Bhoot VN, Kumbier K, Sison-Mangus MP, Brown JB, Kudela R, Newcomer ME
• Veridical data science.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Yu B, Kumbier K
• Definitions, methods, and applications in interpretable machine learning.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Murdoch WJ, Singh C, Kumbier K, Abbasi-Asl R, Yu B
• Iterative random forests to discover predictive and stable high-order interactions.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Basu S, Kumbier K, Brown JB, Yu B