Julie Frouard, PhD
Scientist
Business Service Ctr
Chancellor/EVC/FAS

Publications (19)

Top publication keywords:
HIV InfectionsSequence Analysis, RNADisease ReservoirsCD4-Positive T-LymphocytesT-Lymphocyte SubsetsViremiaInterleukin-7 Receptor alpha SubunitHIV-1ConvalescenceSexually Transmitted Diseases, ViralVirus ReplicationVirusesZika VirusVirus LatencyVirus Internalization

• Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound.
  Immunity 2026 Ma T, George AF, Li Z, Thomas R, Yin K, Shin MG, Montano M, Matsui Y, Ashokkumar M, Young K, Prigann J, Frouard J, Leddy S, Adiba M, Herrde C, Lange UC, Feschotte C, Nixon DF, Browne EP, Archin NM, Li…
• HIV-seq reveals gene expression differences between HIV-transcribing cells from viremic and suppressed people with HIV.
  Nature communications 2026 Frouard J, Telwatte S, Luo X, Gill N, Thomas R, Arneson D, Roychoudhury P, Butte AJ, Wong JK, Hoh R, Deeks SG, Lee SA, Roan NR, Yukl SA
• Defective proviruses cause T cell reprogramming through promoter exaptation in HIV-1 infection.
  bioRxiv : the preprint server for biology 2025 Hamann MV, Brauckmann L, Schwarz C, Spohn M, Stoeck R, Leddy SM, Frouard J, Adiba M, Thiele F, Virdi S, Grundhoff A, Feschotte C, Roan NR, Tolosa E, Lange UC
• Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors.
  Cell reports 2025 George AF, Neidleman J, Luo X, Frouard J, Elphick N, Yin K, Young KC, Ma T, Andrew AK, Ezeonwumelu IJ, Pedersen JG, Chaillon A, Porrachia M, Woodworth B, Jakobsen MR, Thomas R, Smith DM, Gianella S, …
• HIV-SEQ REVEALS GLOBAL HOST GENE EXPRESSION DIFFERENCES BETWEEN HIV-TRANSCRIBING CELLS FROM VIREMIC AND SUPPRESSED PEOPLE WITH HIV.
  bioRxiv : the preprint server for biology 2024 Frouard J, Telwatte S, Luo X, Elphick N, Thomas R, Arneson D, Roychoudhury P, Butte AJ, Wong JK, Hoh R, Deeks SG, Lee SA, Roan NR, Yukl S

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• Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.
  PNAS nexus 2024 Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR, Ndhlovu LC, Gan L, Greene WC
• Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq.
  Frontiers in immunology 2022 Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC
• Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific CD8+ T Cells during Convalescence.
  Journal of immunology (Baltimore, Md. : 1950) 2021 Ma T, Ryu H, McGregor M, Babcock B, Neidleman J, Xie G, George AF, Frouard J, Murray V, Gill G, Ghosn E, Newell EW, Lee SA, Roan NR
• Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence.
  bioRxiv : the preprint server for biology 2021 Ma T, Ryu H, McGregor M, Babcock B, Neidleman J, Xie G, George AF, Frouard J, Murray V, Gill G, Ghosn E, Newell E, Lee S, Roan NR
• Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo.
  Cell reports 2021 Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR
• Long-term Zika virus infection of non-sperm cells in semen.
  The Lancet. Infectious diseases 2020 Mahé D, Bourgeau S, Frouard J, Joguet G, Pasquier C, Bujan L, Dejucq-Rainsford N
• Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir.
  eLife 2020 Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA,…
• SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential.
  Cell reports. Medicine 2020 Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR
• SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential.
  bioRxiv : the preprint server for biology 2020 Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR
• Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
  PLoS pathogens 2020 Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR
• Zika virus infects human testicular tissue and germ cells.
  The Journal of clinical investigation 2018 Matusali G, Houzet L, Satie AP, Mahé D, Aubry F, Couderc T, Frouard J, Bourgeau S, Bensalah K, Lavoué S, Joguet G, Bujan L, Cabié A, Avelar G, Lecuit M, Le Tortorec A, Dejucq-Rainsford N
• [In vitro models for deciphering the mechanisms underlying the sexual transmission of viruses at the mucosal level].
  Virologie (Montrouge, France) 2018 Frouard J, Le Tortorec A, Dejucq-Rainsford N
• In vitro models for deciphering the mechanisms underlying the sexual transmission of viruses at the mucosal level.
  Virology 2017 Frouard J, Le Tortorec A, Dejucq-Rainsford N
• Formyl Peptide Receptor 2 Plays a Deleterious Role During Influenza A Virus Infections.
  The Journal of infectious diseases 2016 Tcherniuk S, Cenac N, Comte M, Frouard J, Errazuriz-Cerda E, Galabov A, Morange PE, Vergnolle N, Si-Tahar M, Alessi MC, Riteau B