Julia Meyer, PhD
Specialist
Pediatrics
School of Medicine

Publications (26)

Top publication keywords:
DNA MethylationDrug Resistance, NeoplasmGuanosine TriphosphateIkaros Transcription FactorGenomicsDrug DiscoveryLeukemia, Myelomonocytic, Juvenile5'-NucleotidaseThioguaninePrecursor B-Cell Lymphoblastic Leukemia-LymphomaMercaptopurineGain of Function Mutationfms-Like Tyrosine Kinase 3Noonan SyndromePrecursor Cell Lymphoblastic Leukemia-Lymphoma

• Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia.
  Haematologica 2022 Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney…
• Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia.
  JAMA oncology 2021 Mangum DS, Meyer JA, Mason CC, Shams S, Maese LD, Gardiner JD, Downie JM, Pei D, Cheng C, Gleason A, Luo M, Pui CH, Aplenc R, Hunger SP, Loh M, Greaves M, Trede N, Raetz E, Frazer JK, Mullighan CG, …
• Genome-wide DNA methylation analysis pre- and post-lenalidomide treatment in patients with myelodysplastic syndrome with isolated deletion (5q).
  Annals of hematology 2021 Hecht A, Meyer JA, Jann JC, Sockel K, Giagounidis A, Götze KS, Letsch A, Haase D, Schlenk RF, Haferlach T, Schafhausen P, Bug G, Lübbert M, Thol F, Büsche G, Schuler E, Nowak V, Obländer J, Fey S, …
• International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Schönung M, Meyer J, Nöllke P, Olshen AB, Hartmann M, Murakami N, Wakamatsu M, Okuno Y, Plass C, Loh ML, Niemeyer CM, Muramatsu H, Flotho C, Stieglitz E, Lipka DB
• Feasibility of monitoring peripheral blood to detect emerging clones in children with acute lymphoblastic leukemia†.
  Pediatric blood & cancer 2020 Saliba J, Evensen NA, Meyer JA, Newman D, Nersting J, Narang S, Ma X, Schmiegelow K, Carroll WL

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• Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.
  Leukemia 2019 Chao AK, Meyer JA, Lee AG, Hecht A, Tarver T, Van Ziffle J, Koegel AK, Golden C, Braun BS, Sweet-Cordero EA, Smith CC, Dvorak CC, Loh ML, Stieglitz E
• Mechanisms of NT5C2-Mediated Thiopurine Resistance in Acute Lymphoblastic Leukemia.
  Molecular cancer therapeutics 2019 Moriyama T, Liu S, Li J, Meyer J, Zhao X, Yang W, Shao Y, Heath R, Hnízda A, Carroll WL, Yang JJ
• Molecular assessment of pretransplant chemotherapy in the treatment of juvenile myelomonocytic leukemia.
  Pediatric blood & cancer 2019 Hecht A, Meyer J, Chehab FF, White KL, Magruder K, Dvorak CC, Loh ML, Stieglitz E
• Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome.
  American journal of human genetics 2019 Capri Y, Flex E, Krumbach OHF, Carpentieri G, Cecchetti S, Lißewski C, Rezaei Adariani S, Schanze D, Brinkmann J, Piard J, Pantaleoni F, Lepri FR, Goh ES, Chong K, Stieglitz E, Meyer J, Kuechler A, …
• MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia.
  Haematologica 2018 Evensen NA, Madhusoodhan PP, Meyer J, Saliba J, Chowdhury A, Araten DJ, Nersting J, Bhatla T, Vincent TL, Teachey D, Hunger SP, Yang J, Schmiegelow K, Carroll WL
• Splice site mutation in factor X gene manifesting as severe intracranial haemorrhage in neonatal period with a challenging treatment course.
  Haemophilia : the official journal of the World Federation of Hemophilia 2016 Madhusoodhan PP, Lu BY, Chen J, Jones CL, Meyer JA, Roman EA, Nardi M, Carroll WL, Bhatla T
• Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues.
  Pediatric blood & cancer 2016 Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR
• Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient.
  Journal of pediatric hematology/oncology 2016 Bhatla T, Dandekar S, Lu BY, Wang J, Han E, Bitterman D, Jones CL, Evensen NA, Magid M, Meyer JA, Carroll WL
• A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia.
  Oncotarget 2015 Wang J, Mi JQ, Debernardi A, Vitte AL, Emadali A, Meyer JA, Charmpi K, Ycart B, Callanan MB, Carroll WL, Khochbin S, Rousseaux S
• State of the art discovery with tumor profiling in pediatric oncology.
  American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 2015 Carroll WL, Raetz E, Meyer J
• The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.
  Journal of pediatric hematology/oncology 2014 Bhatla T, Jones CL, Meyer JA, Vitanza NA, Raetz EA, Carroll WL
• Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.
  Pediatric blood & cancer 2014 Vitanza NA, Zaky W, Blum R, Meyer JA, Wang J, Bhatla T, Morrison DJ, Raetz EA, Carroll WL
• Screening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?
  Expert review of hematology 2013 Meyer JA, Carroll WL, Bhatla T
• HMGA1 overexpression correlates with relapse in childhood B-lineage acute lymphoblastic leukemia.
  Leukemia & lymphoma 2013 Roy S, Di Cello F, Kowalski J, Hristov AC, Tsai HL, Bhojwani D, Meyer JA, Carroll WL, Belton A, Resar LM
• Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.
  Nature genetics 2013 Meyer JA, Wang J, Hogan LE, Yang JJ, Dandekar S, Patel JP, Tang Z, Zumbo P, Li S, Zavadil J, Levine RL, Cardozo T, Hunger SP, Raetz EA, Evans WE, Morrison DJ, Mason CE, Carroll WL
• Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies.
  Blood 2011 Hogan LE, Meyer JA, Yang J, Wang J, Wong N, Yang W, Condos G, Hunger SP, Raetz E, Saffery R, Relling MV, Bhojwani D, Morrison DJ, Carroll WL
• Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles.
  Leukemia 2011 Loudin MG, Wang J, Leung HC, Gurusiddappa S, Meyer J, Condos G, Morrison D, Tsimelzon A, Devidas M, Heerema NA, Carroll AJ, Plon SE, Hunger SP, Basso G, Pession A, Bhojwani D, Carroll WL, Rabin KR
• Identification of an ICP27-responsive element in the coding region of a herpes simplex virus type 1 late gene.
  Journal of virology 2009 Sedlackova L, Perkins KD, Meyer J, Strain AK, Goldman O, Rice SA
• Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia.
  Nature genetics 2009 Mullighan CG, Collins-Underwood JR, Phillips LA, Loudin MG, Liu W, Zhang J, Ma J, Coustan-Smith E, Harvey RC, Willman CL, Mikhail FM, Meyer J, Carroll AJ, Williams RT, Cheng J, Heerema NA, Basso G, …
• The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor.
  Blood 2007 Marango J, Shimoyama M, Nishio H, Meyer JA, Min DJ, Sirulnik A, Martinez-Martinez Y, Chesi M, Bergsagel PL, Zhou MM, Waxman S, Leibovitch BA, Walsh MJ, Licht JD
• NOM1 targets protein phosphatase I to the nucleolus.
  The Journal of biological chemistry 2007 Gunawardena SR, Ruis BL, Meyer JA, Kapoor M, Conklin KF