Joshua Galanter, MD
Assistant Clinical Professor
Medicine
School of Medicine

Publications (50)

Top publication keywords:
Puerto RicoMexican AmericansPopulation DynamicsGenome-Wide Association StudyJanus Kinase InhibitorsGenetic MarkersGenetic Predisposition to DiseaseRespiratory Function TestsSpirometryAlbuterolEnvironmental ExposurePyridonesAsthmaIkaros Transcription FactorDNA Methylation

• Serious Infection Rates Among Patients with Select Autoimmune Conditions: A Claims-Based Retrospective Cohort Study from Taiwan and the USA.
  Rheumatology and therapy 2022 Huang WN, Chuo CY, Lin CH, Chen YM, Lin WS, Tuckwell K, Jones NS, Galanter J, Lindsay L
• Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
  Critical care medicine 2022 Waters M, McKinnell JA, Kalil AC, Martin GS, Buchman TG, Theess W, Yang X, Lekkerkerker AN, Staton T, Rosenberger CM, Pappu R, Wang Y, Zhang W, Brooks L, Cheung D, Galanter J, Chen H, Mohan D, Peck MC…
• Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation.
  Pulmonary pharmacology & therapeutics 2022 Chen H, Kunder R, Zou Y, Staton T, Zhu R, Galanter J, Gugelmann H, Owen R, Grimbaldeston MA, Chang JK, Durk MR, Eliahu A, Wilson MS, Choy DF, Wilson M, Black M, Doppen M, Kung S, Oldfield K, Sparks J,…
• Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC-0214 in healthy volunteers.
  Clinical and translational science 2022 Zhu R, Chen H, Galanter J, She G, Cai F, Durk MR, Zou Y, Chen L, Kenny JR, Vadhavkar S, Warren S, Taylor G, Hwang O, Eliahu A, Wynne C, Owen R
• A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
  Annals of clinical and translational neurology 2022 Katz JS, Rothstein JD, Cudkowicz ME, Genge A, Oskarsson B, Hains AB, Chen C, Galanter J, Burgess BL, Cho W, Kerchner GA, Yeh FL, Ghosh AS, Cheeti S, Brooks L, Honigberg L, Couch JA, Rothenberg ME, …

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• A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of the Monoclonal Antibody MHAA4549A in Patients With Acute Uncomplicated Influenza A Infection.
  Open forum infectious diseases 2021 Lim JJ, Dar S, Venter D, Horcajada JP, Kulkarni P, Nguyen A, McBride JM, Deng R, Galanter J, Chu T, Newton EM, Tavel JA, Peck MC
• Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria: a randomized phase 2 trial.
  Nature medicine 2021 Metz M, Sussman G, Gagnon R, Staubach P, Tanus T, Yang WH, Lim JJ, Clarke HJ, Galanter J, Chinn LW, Chu T, Teterina A, Burgess T, Haddon DJ, Lu TT, Maurer M
• Dose-dependent inactivation of airway tryptase with a novel dissociating anti-tryptase antibody (MTPS9579A) in healthy participants: A randomized trial.
  Clinical and translational science 2021 Rymut SM, Sukumaran S, Sperinde G, Bremer M, Galanter J, Yoshida K, Smith J, Banerjee P, Sverkos V, Cai F, Steffen V, Henderson LM, Rhee H, Belloni PN, Lin JH, Staton TL
• Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial.
  Arthritis & rheumatology (Hoboken, N.J.) 2021 Isenberg D, Furie R, Jones NS, Guibord P, Galanter J, Lee C, McGregor A, Toth B, Rae J, Hwang O, Desai R, Lokku A, Ramamoorthi N, Hackney JA, Miranda P, de Souza VA, Jaller-Raad JJ, Maura Fernandes A,…
• Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial.
  The Journal of allergy and clinical immunology 2021 Braithwaite IE, Cai F, Tom JA, Galanter JM, Owen RP, Zhu R, Williams M, McGregor AG, Eliahu A, Durk MR, Dengler HS, Zak M, Kenny JR, Wilson ME, Beasley R, Chen H
• Regional variations in adverse event reporting rates and ACR responses in placebo/standard-of-care arms of rheumatoid arthritis trials.
  Rheumatology (Oxford, England) 2020 Keebler D, Teng E, Chia J, Galanter J, Peake J, Tuckwell K
• A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of MHAA4549A, a Monoclonal Antibody, plus Oseltamivir in Patients Hospitalized with Severe Influenza A Virus Infection.
  Antimicrobial agents and chemotherapy 2020 Lim JJ, Nilsson AC, Silverman M, Assy N, Kulkarni P, McBride JM, Deng R, Li C, Yang X, Nguyen A, Horn P, Maia M, Castro A, Peck MC, Galanter J, Chu T, Newton EM, Tavel JA
• Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial (ANDES Study).
  Arthritis & rheumatology (Hoboken, N.J.) 2020 Cohen S, Tuckwell K, Katsumoto TR, Zhao R, Galanter J, Lee C, Rae J, Toth B, Ramamoorthi N, Hackney JA, Berman A, Damjanov N, Fedkov D, Jeka S, Chinn LW, Townsend MJ, Morimoto AM, Genovese MC
• Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.
  American journal of respiratory and critical care medicine 2018 Wu AC, Kiley JP, Noel PJ, Amur S, Burchard EG, Clancy JP, Galanter J, Inada M, Jones TK, Kropski JA, Loyd JE, Nogee LM, Raby BA, Rogers AJ, Schwartz DA, Sin DD, Spira A, Weiss ST, Young LR, Himes BE
• A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma.
  The pharmacogenomics journal 2018 Spear ML, Hu D, Pino-Yanes M, Huntsman S, Eng C, Levin AM, Ortega VE, White MJ, McGarry ME, Thakur N, Galanter J, Mak ACY, Oh SS, Ampleford E, Peters SP, Davis A, Kumar R, Farber HJ, Meade K, Avila PC…
• An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.
  The Journal of allergy and clinical immunology 2018 Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, McGarry M, Moreno-Estrada A, …
• Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.
  American journal of respiratory and critical care medicine 2018 Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton…
• An ancestry-based approach for detecting interactions.
  Genetic epidemiology 2017 Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N
• Bringing Lung Function Prediction Equations to Diverse Populations.
  American journal of respiratory and critical care medicine 2017 Galanter JM
• Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation.
  Nature methods 2017 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E
• Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures.
  eLife 2017 Galanter JM, Gignoux CR, Oh SS, Torgerson D, Pino-Yanes M, Thakur N, Eng C, Hu D, Huntsman S, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, Rodríguez-Cintrón W, Kumar …
• Genome-wide methylation data mirror ancestry information.
  Epigenetics & chromatin 2017 Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, Gieger C, Holland N, Burchard EG, …
• Breastfeeding associated with higher lung function in African American youths with asthma.
  The Journal of asthma : official journal of the Association for the Care of Asthma 2016 Oh SS, Du R, Zeiger AM, McGarry ME, Hu D, Thakur N, Pino-Yanes M, Galanter JM, Eng C, Nishimura KK, Huntsman S, Farber HJ, Meade K, Avila P, Serebrisky D, Bibbins-Domingo K, Lenoir MA, Ford JG, …
• Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies.
  American journal of respiratory and critical care medicine 2016 Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, …
• Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies.
  Nature methods 2016 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E
• Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled.
  PLoS medicine 2015 Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu AH, Borrell LN, Gunter C, Powe NR, Burchard EG
• Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, Padhukasahasram B, Moreno-…
• Genetic ancestry influences asthma susceptibility and lung function among Latinos.
  The Journal of allergy and clinical immunology 2014 Pino-Yanes M, Thakur N, Gignoux CR, Galanter JM, Roth LA, Eng C, Nishimura KK, Oh SS, Vora H, Huntsman S, Nguyen EA, Hu D, Drake KA, Conti DV, Moreno-Estrada A, Sandoval K, Winkler CA, Borrell LN, …
• Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits.
  Science (New York, N.Y.) 2014 Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-…
• The lung corps' approach to reducing health disparities in respiratory disease.
  Annals of the American Thoracic Society 2014 Thakur N, McGarry ME, Oh SS, Galanter JM, Finn PW, Burchard EG, ATS Health Equality Committee
• Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.
  The Journal of allergy and clinical immunology 2014 Poole A, Urbanek C, Eng C, Schageman J, Jacobson S, O'Connor BP, Galanter JM, Gignoux CR, Roth LA, Kumar R, Lutz S, Liu AH, Fingerlin TE, Setterquist RA, Burchard EG, Rodriguez-Santana J, Seibold MA
• Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.
  The Journal of allergy and clinical immunology 2014 Galanter JM, Gignoux CR, Torgerson DG, Roth LA, Eng C, Oh SS, Nguyen EA, Drake KA, Huntsman S, Hu D, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, …
• A panel of ancestry informative markers for the complex five-way admixed South African coloured population.
  PloS one 2013 Daya M, van der Merwe L, Galal U, Möller M, Salie M, Chimusa ER, Galanter JM, van Helden PD, Henn BM, Gignoux CR, Hoal E
• Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Thakur N, Oh SS, Nguyen EA, Martin M, Roth LA, Galanter J, Gignoux CR, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, …
• A genome-wide association study of bronchodilator response in Latinos implicates rare variants.
  The Journal of allergy and clinical immunology 2013 Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, Farber HJ, Kumar R, Avila PC, …
• Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.
  American journal of respiratory and critical care medicine 2013 Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell …
• A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.
  The Journal of allergy and clinical immunology 2012 Levin AM, Mathias RA, Huang L, Roth LA, Daley D, Myers RA, Himes BE, Romieu I, Yang M, Eng C, Park JE, Zoratti K, Gignoux CR, Torgerson DG, Galanter JM, Huntsman S, Nguyen EA, Becker AB, Chan-Yeung M,…
• Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.
  The Journal of allergy and clinical immunology 2012 Myers RA, Himes BE, Gignoux CR, Yang JJ, Gauderman WJ, Rebordosa C, Xie J, Torgerson DG, Levin AM, Baurley J, Graves PE, Mathias RA, Romieu I, Roth LA, Conti D, Avila L, Eng C, Vora H, LeNoir MA, Soto…
• Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study.
  PloS one 2012 Aldrich MC, Kumar R, Colangelo LA, Williams LK, Sen S, Kritchevsky SB, Meibohm B, Galanter J, Hu D, Gignoux CR, Liu Y, Harris TB, Ziv E, Zmuda J, Garcia M, Leak TS, Foreman MG, Smith LJ, Fornage M, …
• Effect of secondhand smoke on asthma control among black and Latino children.
  The Journal of allergy and clinical immunology 2012 Oh SS, Tcheurekdjian H, Roth LA, Nguyen EA, Sen S, Galanter JM, Davis A, Farber HJ, Gilliland FD, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, LeNoir MA, Lurmann F, Meade K, …
• Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.
  The Journal of allergy and clinical immunology 2012 Torgerson DG, Gignoux CR, Galanter JM, Drake KA, Roth LA, Eng C, Huntsman S, Torres R, Avila PC, Chapela R, Ford JG, Rodríguez-Santana JR, Rodríguez-Cintrón W, Hernandez RD, Burchard EG
• Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas.
  PLoS genetics 2012 Galanter JM, Fernandez-Lopez JC, Gignoux CR, Barnholtz-Sloan J, Fernandez-Rozadilla C, Via M, Hidalgo-Miranda A, Contreras AV, Figueroa LU, Raska P, Jimenez-Sanchez G, Zolezzi IS, Torres M, Ponte CR, …
• Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population.
  Pediatric allergy, immunology, and pulmonology 2011 Arjomandi M, Galanter JM, Choudhry S, Eng C, Hu D, Beckman K, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Ford J, Avila PC, Burchard EG
• Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
  Nature genetics 2011 Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, …
• Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.
  The Journal of allergy and clinical immunology 2011 Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG
• History shaped the geographic distribution of genomic admixture on the island of Puerto Rico.
  PloS one 2011 Via M, Gignoux CR, Roth LA, Fejerman L, Galanter J, Choudhry S, Toro-Labrador G, Viera-Vera J, Oleksyk TK, Beckman K, Ziv E, Risch N, Burchard EG, Martínez-Cruzado JC
• Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.
  The Journal of allergy and clinical immunology 2010 Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir …
• Genetic ancestry in lung-function predictions.
  The New England journal of medicine 2010 Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara …
• Race, ethnicity and social class and the complex etiologies of asthma.
  Pharmacogenomics 2008 Drake KA, Galanter JM, Burchard EG
• ORMDL3 gene is associated with asthma in three ethnically diverse populations.
  American journal of respiratory and critical care medicine 2008 Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG