Josephine Reijneveld, PhD
Assistant Researcher
Medicine
School of Medicine

Publications (10)

Top publication keywords:
Crystallography, X-RayHost-Pathogen InteractionsReceptors, Antigen, T-CellIntraepithelial LymphocytesAntigens, CD1TuberculosisAntigen PresentationT-LymphocytesMycobacterium tuberculosisPhospholipidsGlycoproteinsAntigens, BacterialGlycolipidsTrehaloseLectins, C-Type

• Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
  The Journal of biological chemistry 2021 Reijneveld JF, Marino L, Cao TP, Cheng TY, Dam D, Shahine A, Witte MD, Filippov DV, Suliman S, van der Marel GA, Moody DB, Minnaard AJ, Rossjohn J, Codée JDC, Van Rhijn I
• Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle.
  Scientific reports 2021 Reijneveld JF, Holzheimer M, Young DC, Lopez K, Suliman S, Jimenez J, Calderon R, Lecca L, Murray MB, Ishikawa E, Yamasaki S, Minnaard AJ, Moody DB, Van Rhijn I
• Human γδ T cells recognize CD1b by two distinct mechanisms.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Reijneveld JF, Ocampo TA, Shahine A, Gully BS, Vantourout P, Hayday AC, Rossjohn J, Moody DB, Van Rhijn I
• All major cholesterol-dependent cytolysins use glycans as cellular receptors.
  Science advances 2020 Shewell LK, Day CJ, Jen FE, Haselhorst T, Atack JM, Reijneveld JF, Everest-Dass A, James DBA, Boguslawski KM, Brouwer S, Gillen CM, Luo Z, Kobe B, Nizet V, von Itzstein M, Walker MJ, Paton AW, Paton …
• Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity.
  ACS chemical biology 2020 Holzheimer M, Reijneveld JF, Ramnarine AK, Misiakos G, Young DC, Ishikawa E, Cheng TY, Yamasaki S, Moody DB, Van Rhijn I, Minnaard AJ

Show all (5 more) Hide

• CD1b Tetramers Broadly Detect T Cells That Correlate With Mycobacterial Exposure but Not Tuberculosis Disease State.
  Frontiers in immunology 2020 Lopez K, Iwany SK, Suliman S, Reijneveld JF, Ocampo TA, Jimenez J, Calderon R, Lecca L, Murray MB, Moody DB, Van Rhijn I
• A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins.
  Journal of immunology (Baltimore, Md. : 1950) 2019 Reinink P, Shahine A, Gras S, Cheng TY, Farquhar R, Lopez K, Suliman SA, Reijneveld JF, Le Nours J, Tan LL, León SR, Jimenez J, Calderon R, Lecca L, Murray MB, Rossjohn J, Moody DB, Van Rhijn I
• A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
  Nature communications 2019 Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I
• T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
  Nature immunology 2018 Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, …
• CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.
  Cell chemical biology 2018 James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, …