Joseph Sullivan, MD
Professor
Neurology
School of Medicine

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2019
• M.D. School of Medicine Albany 1998

Websites

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• Clinical Profile at UCSF Benioff Children's Hospital (ucsfbenioffchildrens.org)

Publications (57)

Top publication keywords:
ElectroencephalographyExecutive FunctionEpilepsyMonitoring, PhysiologicElectric Stimulation TherapyPediatricsWechsler ScalesInfantSeizuresSpasms, InfantileFenfluramineDrug Resistant EpilepsyEpilepsies, MyoclonicAnticonvulsantsLennox Gastaut Syndrome

• Pulseless Electrical Activity Arrest Presenting as Tonic Arm Stiffening and a Flat Electroencephalogram.
  The Neurohospitalist 2024 Mahmood N, Gonzalez-Giraldo E, Sullivan JE
• Adaptive functioning and neurodevelopment in patients with Dravet syndrome: 12-month interim analysis of the BUTTERFLY observational study.
  Epilepsy & behavior : E&B 2024 Sullivan J, Wirrell E, Knupp KG, Chen D, Flamini R, Zafar M, Ventola P, Avendaño J, Wang F, Parkerson KA, Ticho B
• Fenfluramine Treatment Is Associated With Improvement in Everyday Executive Function in Adults With Lennox-Gastaut Syndrome: Post-Hoc Analysis of Dose Effects From a Phase 3 Trial Rationale (P11-1.001).
  Neurology 2023 Kim Bishop, Peter Isquith, Kelly Knupp, Joseph Sullivan, Rima Nabbout, Antonio Gil-Nagel, Ingrid Scheffer, Stéphane Auvin, J Helen Cross, Renzo Guerrini, Robert Roth, Gerard Gioia, Amélie Lothe, …
• Impact of Fenfluramine on Drop Seizure Frequency in Adults or Dose-Capped Patients With Lennox-Gastaut Syndrome: Comparative Analysis of Clinical Trial Data (S44.002).
  Neurology 2023 Kelly G. Knupp, Ingrid E. Scheffer, Berten Ceulemans, Joseph Sullivan, Katherine C. Nickels, Lieven Lagae, Renzo Guerrini, Sameer M. Zuberi, Rima Nabbout, Kate Riney, Shikha Polega, Amélie Lothe, …
• Genetic Testing in Patients With Epilepsy May Impact Treatments and Improve Outcomes.
  JAMA neurology 2022 Sullivan JE

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• Interim results of adaptive functioning and neurodevelopment in BUTTERFLY - An observational study of children and adolescents with Dravet syndrome.
  Epilepsy & behavior : E&B 2022 Sullivan J, Wirrell E, Knupp KG, Chen D, Zafar M, Flamini R, Stutely J, Brathwaite C, Ventola P, Avendaño J, Parkerson KA, Wyant N, Ticho B
• Dravet Syndrome as an Example of Precision Medicine in Epilepsy.
  Epilepsy Currents 2022 Joseph Sullivan, Elaine C Wirrell
• Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome: A Randomized Clinical Trial.
  JAMA neurology 2022 Knupp KG, Scheffer IE, Ceulemans B, Sullivan JE, Nickels KC, Lagae L, Guerrini R, Zuberi SM, Nabbout R, Riney K, Shore S, Agarwal A, Lock M, Farfel GM, Galer BS, Gammaitoni AR, Davis R, Gil-Nagel A
• Fenfluramine Improves Everyday Executive Functioning in Patients With Lennox-Gastaut Syndrome: Analysis of Phase 3 Data (P12-8.004).
  Neurology 2022 Kim Bishop, Peter Isquith, Gerard Giola, Kelly Knupp, Joseph Sullivan, Rima Nabbout, Gail Farfel, Bradley Galer, Arnold Gammaitoni
• Interim Analysis of Long-Term Safety and Efficacy of FINTEPLA (fenfluramine) in Patients with Lennox-Gastaut Syndrome (S13.010).
  Neurology 2022 Kelly Knupp, Ingrid Scheffer, Berten Ceulemans, Joseph Sullivan, Katherine Nickels, Lieven Lagae, Renzo Guerrini, Sameer M. Zuberi, Rima Nabbout, Kate Riney, Svetlana Shore, Anupam Agarwal, Michael …
• Fenfluramine Treatment Improves Everyday Executive Functioning in Patients with Lennox-Gastaut Syndrome: Analysis from a Phase 3 Clinical Trial.
  Neuropediatrics 2021 K. I. Bishop, P. K. Isquith, G. A. Gioia, K. G. Knupp, I. E. Scheffer, J. Sullivan, R. Nabbout, G. Farfel, B. S. Galer, S. Shore, J. Grünert, A. R. Gammaitoni
• What Magnitude of Reduction Is a “Clinically Meaningful” Change in Seizure Frequency? Analysis of Long-Term Fenfluramine Phase 3 Dravet Syndrome Data.
  Neuropediatrics 2021 T. Polster, A. Gammaitoni, J. Sullivan, S. Perry, E. Wirrell, G. Farfel, B. Galer, R. Nabbout
• Impact of intellectual and developmental disability on quality-of-life priorities in adults with epilepsy.
  Epilepsy & behavior : E&B 2021 Chiang S, Moss R, Meskis MA, Vogel-Farley V, Sullivan JE, Patel AD, Rao VR
• Dravet syndrome: a quick transition guide for the adult neurologist.
  Epilepsy Research 2021 Danielle M. Andrade, Anne T. Berg, Veronica Hood, Kelly G. Knupp, Sookyong Koh, Linda Laux, Mary Anne Meskis, Ian Miller, M. Scott Perry, Ingrid E. Scheffer, Joseph Sullivan, Nicole Villas, Elaine …
• Fenfluramine for treatment-resistant epilepsy in Dravet syndrome and other genetically mediated epilepsies.
  Drugs of today (Barcelona, Spain : 1998) 2021 Sullivan J, Simmons R
• Raising the bar: Fenfluramine sets new treatment standards for Dravet syndrome.
  Epilepsy & behavior : E&B 2021 Sullivan J, Helen Cross J
• PIH4 NUMBER NEEDED TO TREAT (NNT) WITH FENFLURAMINE TO ACHIEVE A CLINICALLY MEANINGFUL REDUCTION IN CONVULSIVE SEIZURE FREQUENCY IN PATIENTS WITH DRAVET SYNDROME: HEALTH ECONOMIC IMPLICATIONS.
  Value in Health 2020 J. Sullivan, D. Dlugos, R. Nabbout, D. Haney, G. Morrison, G.M. Farfel, B.S. Galer, A. Gammaitoni
• Long-Term (2-Year) Safety and Efficacy of Adjunctive ZX008 (Fenfluramine Hydrochloride Oral Solution) for Dravet Syndrome: Interim Results of an Ongoing Open-Label Extension Study (4684).
  Neurology 2020 Joseph Sullivan, Stéphane Auvin, Milka Pringsheim, Kelly Knupp, Elaine Wirrell, Gail Farfel, Bradley Galer, Glenn Morrison, Michael Lock, Arnold Gammaitoni, Elizabeth Thiele
• Quantifying “Clinically Meaningful Changes” in Seizure Frequency - Data from Three Phase 3 Studies of ZX008 (Fenfluramine Hydrochloride Oral Solution) in Dravet Syndrome: Do Expectations and Views Change Over Time? (2247).
  Neurology 2020 Arnold Gammaitoni, Joseph Sullivan, Dennis Dlugos, Gail M. Farfel, Bradley S. Galer, Glenn Morrison, Douglas Haney, Rima Nabbout
• Advances in the Treatment of Drug-Resistant Pediatric Epilepsy.
  Seminars in neurology 2020 Gonzalez-Giraldo E, Sullivan JE
• Immediate outcomes in early life epilepsy: A contemporary account.
  Epilepsy & behavior : E&B 2019 Berg AT, Wusthoff C, Shellhaas RA, Loddenkemper T, Grinspan ZM, Saneto RP, Knupp KG, Patel A, Sullivan JE, Kossoff EH, Chu CJ, Massey S, Valencia I, Keator C, Wirrell EC, Coryell J, Millichap JJ, …
• Schizophrenia is a later-onset feature of PCDH19 Girls Clustering Epilepsy.
  Epilepsia 2019 Vlaskamp DRM, Bassett AS, Sullivan JE, Robblee J, Sadleir LG, Scheffer IE, Andrade DM
• Current Treatment Strategies and Future Treatment Options for Dravet Syndrome.
  Current treatment options in neurology 2018 Ziobro J, Eschbach K, Sullivan JE, Knupp KG
• Neuroimaging of Early Life Epilepsy.
  Pediatrics 2018 Coryell J, Gaillard WD, Shellhaas RA, Grinspan ZM, Wirrell EC, Knupp KG, Wusthoff CJ, Keator C, Sullivan JE, Loddenkemper T, Patel A, Chu CJ, Massey S, Novotny EJ, Saneto RP, Berg AT
• Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy.
  JAMA pediatrics 2018 Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ, Millichap J…
• Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy.
  Epilepsy & behavior case reports 2018 Singhal NS, Numis AL, Lee MB, Chang EF, Sullivan JE, Auguste KI, Rao VR
• Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms.
  PloS one 2018 Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ,…
• De Novo Mutations in PPP3CA Cause Severe Neurodevelopmental Disease with Seizures.
  American journal of human genetics 2017 Myers CT, Stong N, Mountier EI, Helbig KL, Freytag S, Sullivan JE, Ben Zeev B, Nissenkorn A, Tzadok M, Heimer G, Shinde DN, Rezazadeh A, Regan BM, Oliver KL, Ernst ME, Lippa NC, Mulhern MS, Ren Z, …
• Early-Life Epilepsies and the Emerging Role of Genetic Testing.
  JAMA pediatrics 2017 Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, …
• Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus.
  Pediatric neurology 2017 Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I,…
• A multicenter, open-label trial of ganaxolone in children with PCDH19 epilepsy (P5.236).
  Neurology 2017 Jaakko Lappalainen, Michael Chez, Joseph Sullivan, Jozef Gecz, Nicola Specchio, Albena Patroneva
• 68 Epileptic Spasms and Myoclonic Seizures.
  Swaiman\u0027s Pediatric Neurology 2017 Nilika Shah Singhal, Chellamani Harini, Joseph Sullivan
• Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study.
  Neurology 2014 Rothman SM, Glass HC, Chang T, Sullivan JE, Bonifacio SL, Shellhaas RA
• Epilepsy surgery failure in children: a quantitative and qualitative analysis.
  Journal of neurosurgery. Pediatrics 2014 Englot DJ, Han SJ, Rolston JD, Ivan ME, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI
• Continuous Spike-Wave during Slow Wave Sleep and Related Conditions.
  ISRN neurology 2014 Singhal NS, Sullivan JE
• KCNQ2 encephalopathy: delineation of the electroclinical phenotype and treatment response.
  Neurology 2013 Numis AL, Angriman M, Sullivan JE, Lewis AJ, Striano P, Nabbout R, Cilio MR
• Effects of temporal lobectomy on consciousness-impairing and consciousness-sparing seizures in children.
  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2013 Englot DJ, Rutkowski MJ, Ivan ME, Sun PP, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI
• American clinical neurophysiology society standardized EEG terminology and categorization for the description of continuous EEG monitoring in neonates: report of the American Clinical Neurophysiology Society critical care monitoring committee.
  Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2013 Tsuchida TN, Wusthoff CJ, Shellhaas RA, Abend NS, Hahn CD, Sullivan JE, Nguyen S, Weinstein S, Scher MS, Riviello JJ, Clancy RR, American Clinical Neurophysiology Society Critical Care Monitoring …
• Focal cortical dysplasia is more common in boys than in girls.
  Epilepsy & behavior : E&B 2013 Ortiz-González XR, Poduri A, Roberts CM, Sullivan JE, Marsh ED, Porter BE
• Chapter 56 Myoclonic Seizures and Infantile Spasms.
  Swaiman\u0027s Pediatric Neurology 2012 Kendall Nash, Joseph Sullivan
• Risk factors for epilepsy in children with neonatal encephalopathy.
  Pediatric research 2011 Glass HC, Hong KJ, Rogers EE, Jeremy RJ, Bonifacio SL, Sullivan JE, Barkovich AJ, Ferriero DM
• Seizures and magnetic resonance imaging-detected brain injury in newborns cooled for hypoxic-ischemic encephalopathy.
  The Journal of pediatrics 2011 Glass HC, Nash KB, Bonifacio SL, Barkovich AJ, Ferriero DM, Sullivan JE, Cilio MR
• Predictors of seizure freedom after surgery for malformations of cortical development.
  Annals of neurology 2011 Chang EF, Wang DD, Barkovich AJ, Tihan T, Auguste KI, Sullivan JE, Garcia PA, Barbaro NM
• Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients.
  Journal of neurosurgery. Pediatrics 2010 Chang EF, Christie C, Sullivan JE, Garcia PA, Tihan T, Gupta N, Berger MS, Barbaro NM
• Neonatal seizures.
  Current treatment options in neurology 2009 Glass HC, Sullivan JE
• Challenges in pediatric video-EEG monitoring.
  American journal of electroneurodiagnostic technology 2007 Sullivan JE, Corcoran-Donnelly M, Dlugos DJ
• RETROSPECTIVE ANALYSIS OF THE PROGNOSTIC VALUE OF ELECTROENCEPHALOGRAPHY PATTERNS OBTAINED IN PEDIATRIC IN-HOSPITAL CARDIAC ARREST SURVIVORS OVER THREE YEARS.
  Pediatric Critical Care Medicine 2007 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• RETROSPECTIVE ANALYSIS OF THE PROGNOSTIC VALUE OF ELECTROENCEPHALOGRAPHY PATTERNS OBTAINED IN PEDIATRIC IN-HOSPITAL CARDIAC ARREST SURVIVORS OVER THREE YEARS.
  Pediatric Critical Care Medicine 2007 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• RETROSPECTIVE ANALYSIS OF THE PROGNOSTIC VALUE OF ELECTROENCEPHALOGRAPHY PATTERNS OBTAINED IN PEDIATRIC IN-HOSPITAL CARDIAC ARREST SURVIVORS OVER THREE YEARS.
  Pediatric Critical Care Medicine 2007 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• RETROSPECTIVE ANALYSIS OF THE PROGNOSTIC VALUE OF ELECTROENCEPHALOGRAPHY PATTERNS OBTAINED IN PEDIATRIC IN-HOSPITAL CARDIAC ARREST SURVIVORS OVER THREE YEARS.
  Pediatric Critical Care Medicine 2007 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• Retrospective analysis of the prognostic value of electroencephalography patterns obtained in pediatric in-hospital cardiac arrest survivors over three years.
  Pediatric Critical Care Medicine 2007 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• Retrospective analysis of the prognostic value of electroencephalography patterns obtained in pediatric in-hospital cardiac arrest survivors during three years*.
  Pediatric Critical Care Medicine 2006 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey R. Bayer, Dennis Dlugos, Richard Lin, Rebecca Ichord, Mark A. Helfaer, Vinay Nadkarni
• HYPOCAPNEA IMMEDIATELY AFTER ROSC IS ASSOCIATED WITH GOOD NEUROLOGIC OUTCOME IN PEDIATRIC IN-HOSPITAL CARDIAC ARREST.
  Pediatric Critical Care Medicine 2006 Akira Nishisaki, Joseph Sullivan, Bernhard Steger, Carey Bayer, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni
• ELECTROENCEPHALOGRAPHY(EEG) HAS PROGNOSTIC VALUE FOR NEUROLOGIC OUTCOME IN CHILDREN SURVIVING > 24 HOURS AFTER IN-HOSPITAL CARDIAC ARREST(CA).
  Critical Care Medicine 2005 Akira Nishisaki, Carey Roth Bayer, Troy Dominguez, Richard Lin, Mark A Helfaer, Vinay Nadkarni, Joseph E Sullivan, Rebecca Ichord, Bernhard Steger
• Antiepileptic drug monotherapy: pediatric concerns.
  Seminars in pediatric neurology 2005 Sullivan JE, Dlugos DJ
• A TALE OF TWO CITIES: TIMING OF BRAIN IMAGING AND NEUROPHYSIOLOGIC ASSESSMENTS FOLLOWING IN-HOSPITAL PEDIATRIC CARDIAC ARREST.
  Critical Care Medicine 2004 Akira Nishisaki, Joseph Sullivan, Bernhard Stegher, Rebecca Ichord, Mark A Helfaer, Vinay Nadkarni, Naoki Shimizu, Katsuyuki Miyasaka
• Idiopathic Generalized Epilepsy.
  Current treatment options in neurology 2004 Sullivan JE, Dlugos DJ