Joseph Geradts, MD, MA
Professor
Pathology
School of Medicine

Publications (168)

Top publication keywords:
Receptor, ErbB-2ImmunohistochemistryBiomarkers, TumorReceptors, ProgesteroneCarcinoma, Ductal, BreastProto-Oncogene Proteins c-etsCyclin-Dependent Kinase Inhibitor p16Retinoblastoma ProteinSpectrum AnalysisCarcinoma, Intraductal, NoninfiltratingBreast NeoplasmsDNA Copy Number VariationsTumor Suppressor Protein p53Receptors, EstrogenGene Expression Regulation, Neoplastic

• XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
  Translational oncology 2024 Van Berckelaer C, Van Laere S, Lee S, Morse MA, Geradts J, Dirix L, Kockx M, Bertucci F, Van Dam P, Devi GR
• Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation.
  Nature communications 2024 Kim WK, Buckley AJ, Lee DH, Hiroto A, Nenninger CH, Olson AW, Wang J, Li Z, Vikram R, Adzavon YM, Yau TY, Bao Y, Kahn M, Geradts J, Xiao GQ, Sun Z
• Predicting early breast cancer recurrence from histopathological images in the Carolina Breast Cancer Study.
  NPJ breast cancer 2023 Shi Y, Olsson LT, Hoadley KA, Calhoun BC, Marron JS, Geradts J, Niethammer M, Troester MA
• Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development.
  bioRxiv : the preprint server for biology 2023 Ryser MD, Greenwald MA, Sorribes IC, King LM, Hall A, Geradts J, Weaver DL, Mallo D, Holloway S, Monyak D, Gumbert G, Vaez-Ghaemi S, Wu E, Murgas K, Grimm LJ, Maley CC, Marks JR, Shibata D, Hwang ES
• Differential distribution of actual and surrogate oncotype DX recurrence scores in breast cancer patients by age, menopausal status, race, and body mass index.
  Breast cancer research and treatment 2023 Mohamed A, Olsson LT, Geradts J

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• Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay.
  Breast cancer research and treatment 2023 Hurson AN, Hamilton AM, Olsson LT, Kirk EL, Sherman ME, Calhoun BC, Geradts J, Troester MA
• Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.
  Nature communications 2022 Hiroto A, Kim WK, Pineda A, He Y, Lee DH, Le V, Olson AW, Aldahl J, Nenninger CH, Buckley AJ, Xiao GQ, Geradts J, Sun Z
• Pathobiologic Stratification of Oncotype DX Recurrence Scores and Comparative Validation of 3 Surrogate Models.
  Archives of pathology & laboratory medicine 2022 Mohamed A, Kousar A, Wong J, Vohra N, Muzaffar M, Geradts J
• Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.
  Nature communications 2022 Rebbeck CA, Xian J, Bornelöv S, Geradts J, Hobeika A, Geiger H, Alvarez JF, Rozhkova E, Nicholls A, Robine N, Lyerly HK, Hannon GJ
• Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
  Oncogene 2022 Cao X, Geradts J, Dewhirst MW, Lo HW
• JOINT AND INDIVIDUAL ANALYSIS OF BREAST CANCER HISTOLOGIC IMAGES AND GENOMIC COVARIATES.
  The annals of applied statistics 2021 Carmichael I, Calhoun BC, Hoadley KA, Troester MA, Geradts J, Couture HD, Olsson L, Perou CM, Niethammer M, Hannig J, Marron JS
• Race-Related Differences in the Clinical Presentation and Histopathologic Features of Phyllodes Tumor.
  The American surgeon 2021 Johnson HM, Mohamed A, Hassan MM, Geradts J, Geisel L, Vohra NA, Wong JH
• Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy.
  Cancers 2021 Devi GR, Finetti P, Morse MA, Lee S, de Nonneville A, Van Laere S, Troy J, Geradts J, McCall S, Bertucci F
• Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies.
  WIREs mechanisms of disease 2020 Frankhauser DE, Jovanovic-Talisman T, Lai L, Yee LD, Wang LV, Mahabal A, Geradts J, Rockne RC, Tomsic J, Jones V, Sistrunk C, Miranda-Carboni G, Dietze EC, Erhunmwunsee L, Hyslop T, Seewaldt VL
• Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features.
  JNCI cancer spectrum 2020 Benefield HC, Reeder-Hayes KE, Nichols HB, Calhoun BC, Love MI, Kirk EL, Geradts J, Hoadley KA, Cole SR, Earp HS, Olshan AF, Carey LA, Perou CM, Troester MA
• Quantitative assessment of distant recurrence risk in early stage breast cancer using a nonlinear combination of pathological, clinical and imaging variables.
  Journal of biophotonics 2020 Nichols BS, Chelales E, Wang R, Schulman A, Gallagher J, Greenup RA, Geradts J, Harter J, Marcom PK, Wilke LG, Ramanujam N
• Borderline Estrogen Receptor-Positive Breast Cancers in Black and White Women.
  Journal of the National Cancer Institute 2020 Benefield HC, Allott EH, Reeder-Hayes KE, Perou CM, Carey LA, Geradts J, Sun X, Calhoun BC, Troester MA
• Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.
  Oncogene 2020 He Y, Mi J, Olson A, Aldahl J, Hooker E, Yu EJ, Le V, Lee DH, Kim WK, Robins DM, Geradts J, Sun Z
• Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer.
  Annals of oncology : official journal of the European Society for Medical Oncology 2020 Waks AG, Cohen O, Kochupurakkal B, Kim D, Dunn CE, Buendia Buendia J, Wander S, Helvie K, Lloyd MR, Marini L, Hughes ME, Freeman SS, Ivy SP, Geradts J, Isakoff S, LoRusso P, Adalsteinsson VA, Tolaney …
• DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.
  NPJ breast cancer 2020 Fackler MJ, Cho S, Cope L, Gabrielson E, Visvanathan K, Wilsbach K, Meir-Levi D, Lynch CF, Marks J, Geradts J, Regan MM, Viale G, Wolff AC, Sukumar S, Umbricht CB
• Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration.
  PLoS genetics 2020 Le V, He Y, Aldahl J, Hooker E, Yu EJ, Olson A, Kim WK, Lee DH, Wong M, Sheng R, Mi J, Geradts J, Cunha GR, Sun Z
• Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis.
  The Journal of biological chemistry 2019 Aldahl J, Mi J, Pineda A, Kim WK, Olson A, Hooker E, He Y, Yu EJ, Le V, Lee DH, Geradts J, Sun Z
• The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.
  PLoS genetics 2019 Olson A, Le V, Aldahl J, Yu EJ, Hooker E, He Y, Lee DH, Kim WK, Cardiff RD, Geradts J, Sun Z
• Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications.
  Breast cancer research and treatment 2019 Allott EH, Shan Y, Chen M, Sun X, Garcia-Recio S, Kirk EL, Olshan AF, Geradts J, Earp HS, Carey LA, Perou CM, Pfeiffer RM, Anderson WF, Troester MA
• Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate.
  Oncogene 2019 He Y, Johnson DT, Yang JS, Wu H, You S, Yoon J, Lee DH, Kim WK, Aldahl J, Le V, Hooker E, Yu EJ, Geradts J, Cardiff RD, Sun Z
• Mammographic density: intersection of advocacy, science, and clinical practice.
  Current breast cancer reports 2019 Tossas-Milligan K, Shalabi S, Jones V, Keely PJ, Conklin MW, Eliceiri KW, Winn R, Sistrunk C, Geradts J, Miranda-Carboni G, Dietze EC, Yee LD, Seewaldt VL
• CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.
  Nature communications 2019 Racioppi L, Nelson ER, Huang W, Mukherjee D, Lawrence SA, Lento W, Masci AM, Jiao Y, Park S, York B, Liu Y, Baek AE, Drewry DH, Zuercher WJ, Bertani FR, Businaro L, Geradts J, Hall A, Means AR, Chao N…
• Expression of tetraspanins NET-6 and CD151 in breast cancer as a potential tumor biomarker.
  Clinical and experimental medicine 2019 Jiang L, Zhang X, Geradts J, Wei Q, Hochwald S, Xu H, Huang H
• Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate.
  PloS one 2019 Lee DH, Yu EJ, Aldahl J, Yang J, He Y, Hooker E, Le V, Mi J, Olson A, Wu H, Geradts J, Xiao GQ, Gonzalgo ML, Cardiff RD, Sun Z
• Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas.
  Cancer causes & control : CCC 2019 Williams LA, Hoadley KA, Nichols HB, Geradts J, Perou CM, Love MI, Olshan AF, Troester MA
• Image analysis with deep learning to predict breast cancer grade, ER status, histologic subtype, and intrinsic subtype.
  NPJ breast cancer 2018 Couture HD, Williams LA, Geradts J, Nyante SJ, Butler EN, Marron JS, Perou CM, Troester MA, Niethammer M
• Circulating Biomarkers and Resistance to Endocrine Therapy in Metastatic Breast Cancers: Correlative Results from AZD9496 Oral SERD Phase I Trial.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Paoletti C, Schiavon G, Dolce EM, Darga EP, Carr TH, Geradts J, Hoch M, Klinowska T, Lindemann J, Marshall G, Morgan S, Patel P, Rowlands V, Sathiyayogan N, Aung K, Hamilton E, Patel M, Armstrong A, …
• Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Detre S, Dowsett M, Jeselsohn RM, Liu XS, Brown M
• TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases.
  NPJ breast cancer 2018 Williams LA, Butler EN, Sun X, Allott EH, Cohen SM, Fuller AM, Hoadley KA, Perou CM, Geradts J, Olshan AF, Troester MA
• Differential cellular localization of CELSR2 and ING4 and correlations with hormone receptor status in breast cancer.
  Histology and histopathology 2018 Jiang L, Zhang X, Xiang C, Geradts J, Wei Q, Liang Y, Huang H, Xu JF
• Frequency of breast cancer subtypes among African American women in the AMBER consortium.
  Breast cancer research : BCR 2018 Allott EH, Geradts J, Cohen SM, Khoury T, Zirpoli GR, Bshara W, Davis W, Omilian A, Nair P, Ondracek RP, Cheng TD, Miller CR, Hwang H, Thorne LB, O'Connor S, Bethea TN, Bell ME, Hu Z, Li Y, Kirk EL, …
• Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.
  Journal of the National Cancer Institute 2018 Troester MA, Sun X, Allott EH, Geradts J, Cohen SM, Tse CK, Kirk EL, Thorne LB, Mathews M, Li Y, Hu Z, Robinson WR, Hoadley KA, Olopade OI, Reeder-Hayes KE, Earp HS, Olshan AF, Carey LA, Perou CM
• XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype.
  Cancer research 2018 Evans MK, Brown MC, Geradts J, Bao X, Robinson TJ, Jolly MK, Vermeulen PB, Palmer GM, Gromeier M, Levine H, Morse MA, Van Laere SJ, Devi GR
• Prediagnostic Smoking Is Associated with Binary and Quantitative Measures of ER Protein and ESR1 mRNA Expression in Breast Tumors.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2017 Butler EN, Bensen JT, Chen M, Conway K, Richardson DB, Sun X, Geradts J, Olshan AF, Troester MA
• Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study.
  Cancer causes & control : CCC 2017 Williams LA, Nichols HB, Hoadley KA, Tse CK, Geradts J, Bell ME, Perou CM, Love MI, Olshan AF, Troester MA
• Ki-67 Expression in Breast Cancer Tissue Microarrays: Assessing Tumor Heterogeneity, Concordance With Full Section, and Scoring Methods.
  American journal of clinical pathology 2017 Khoury T, Zirpoli G, Cohen SM, Geradts J, Omilian A, Davis W, Bshara W, Miller R, Mathews MM, Troester M, Palmer JR, Ambrosone CB
• Prostate-derived Ets factor, an oncogenic driver in breast cancer.
  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Sood AK, Geradts J, Young J
• Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins.
  Journal of biomedical optics 2017 Nichols BS, Llopis A, Palmer GM, McCachren SS, Senlik O, Miller D, Brooke MA, Jokerst NM, Geradts J, Greenup R, Ramanujam N
• CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
  Cancer research 2017 Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Thompson JW, Dubois LG, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ
• Rational Manual and Automated Scoring Thresholds for the Immunohistochemical Detection of TP53 Missense Mutations in Human Breast Carcinomas.
  Applied immunohistochemistry & molecular morphology : AIMM 2016 Taylor NJ, Nikolaishvili-Feinberg N, Midkiff BR, Conway K, Millikan RC, Geradts J
• Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification.
  Breast cancer research : BCR 2016 Allott EH, Geradts J, Sun X, Cohen SM, Zirpoli GR, Khoury T, Bshara W, Chen M, Sherman ME, Palmer JR, Ambrosone CB, Olshan AF, Troester MA
• Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma.
  International journal of clinical and experimental pathology 2016 Canfield K, Wells W, Geradts J, Kinlaw WB, Cheng C, Kurokawa M
• Correlation of breast tissue histology and optical signatures to improve margin assessment techniques.
  Journal of biomedical optics 2016 Kennedy S, Caldwell M, Bydlon T, Mulvey C, Mueller J, Wilke L, Barry W, Ramanujam N, Geradts J
• Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS).
  Breast cancer research and treatment 2016 Geradts J, Groth J, Wu Y, Jin G
• Rapid staining and imaging of subnuclear features to differentiate between malignant and benign breast tissues at a point-of-care setting.
  Journal of cancer research and clinical oncology 2016 Mueller JL, Gallagher JE, Chitalia R, Krieger M, Erkanli A, Willett RM, Geradts J, Ramanujam N
• Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2015 Allott EH, Cohen SM, Geradts J, Sun X, Khoury T, Bshara W, Zirpoli GR, Miller CR, Hwang H, Thorne LB, O'Connor S, Tse CK, Bell MB, Hu Z, Li Y, Kirk EL, Bethea TN, Perou CM, Palmer JR, Ambrosone CB, …
• FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target.
  Radiation research 2015 Horton JK, Siamakpour-Reihani S, Lee CT, Zhou Y, Chen W, Geradts J, Fels DR, Hoang P, Ashcraft KA, Groth J, Kung HN, Dewhirst MW, Chi JT
• CHAMBER: A Regional Performance Improvement CME Initiative for Breast Cancer Health Care Providers.
  Journal of the National Comprehensive Cancer Network : JNCCN 2015 Sutton LM, Geradts J, Hamilton EP, Havlin KA, Kimmick GG, Marcom PK, Spector NL, Watson M, Rabin DU, Bruno TO, Noe A, Miller S, Subramaniam C, Layton S, Grichnik K
• Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance.
  Breast cancer research : BCR 2015 Li S, Payne S, Wang F, Claus P, Su Z, Groth J, Geradts J, de Ridder G, Alvarez R, Marcom PK, Pizzo SV, Bachelder RE
• A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins.
  PloS one 2015 Nichols BS, Schindler CE, Brown JQ, Wilke LG, Mulvey CS, Krieger MS, Gallagher J, Geradts J, Greenup RA, Von Windheim JA, Ramanujam N
• A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins.
  International journal of cancer 2015 Mueller JL, Fu HL, Mito JK, Whitley MJ, Chitalia R, Erkanli A, Dodd L, Cardona DM, Geradts J, Willett RM, Kirsch DG, Ramanujam N
• Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers.
  International journal of radiation oncology, biology, physics 2015 Horton JK, Blitzblau RC, Yoo S, Geradts J, Chang Z, Baker JA, Georgiade GS, Chen W, Siamakpour-Reihani S, Wang C, Broadwater G, Groth J, Palta M, Dewhirst M, Barry WT, Duffy EA, Chi JT, Hwang ES
• DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival.
  Breast cancer research : BCR 2014 Conway K, Edmiston SN, May R, Kuan PF, Chu H, Bryant C, Tse CK, Swift-Scanlan T, Geradts J, Troester MA, Millikan RC
• A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.
  Breast cancer research : BCR 2014 Cheng Q, Chang JT, Gwin WR, Zhu J, Ambs S, Geradts J, Lyerly HK
• Automated, quantitative analysis of histopathological staining in nuclei.
  AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 2014 Henao R, Geradts J, Kurokawa M, Kornbluth S, Lucas JE
• 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
  Science (New York, N.Y.) 2013 Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP
• αB-crystallin: a novel regulator of breast cancer metastasis to the brain.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Malin D, Strekalova E, Petrovic V, Deal AM, Al Ahmad A, Adamo B, Miller CR, Ugolkov A, Livasy C, Fritchie K, Hamilton E, Blackwell K, Geradts J, Ewend M, Carey L, Shusta EV, Anders CK, Cryns VL
• Optical spectral surveillance of breast tissue landscapes for detection of residual disease in breast tumor margins.
  PloS one 2013 Brown JQ, Bydlon TM, Kennedy SA, Caldwell ML, Gallagher JE, Junker M, Wilke LG, Barry WT, Geradts J, Ramanujam N
• Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins.
  PloS one 2013 Mueller JL, Harmany ZT, Mito JK, Kennedy SA, Kim Y, Dodd L, Geradts J, Kirsch DG, Willett RM, Brown JQ, Ramanujam N
• A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
  Science signaling 2013 Kurokawa M, Kim J, Geradts J, Matsuura K, Liu L, Ran X, Xia W, Ribar TJ, Henao R, Dewhirst MW, Kim WJ, Lucas JE, Wang S, Spector NL, Kornbluth S
• Multidisciplinary care of patients with early-stage breast cancer.
  Surgical oncology clinics of North America 2013 Lyman GH, Baker J, Geradts J, Horton J, Kimmick G, Peppercorn J, Pruitt S, Scheri RP, Hwang ES
• Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast.
  PloS one 2012 Bydlon TM, Barry WT, Kennedy SA, Brown JQ, Gallagher JE, Wilke LG, Geradts J, Ramanujam N
• Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast.
  Genes, chromosomes & cancer 2012 Liao S, Desouki MM, Gaile DP, Shepherd L, Nowak NJ, Conroy J, Barry WT, Geradts J
• Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.
  Breast cancer research : BCR 2012 Cheng Q, Chang JT, Geradts J, Neckers LM, Haystead T, Spector NL, Lyerly HK
• Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.
  Breast cancer research : BCR 2011 Adamo B, Deal AM, Burrows E, Geradts J, Hamilton E, Blackwell KL, Livasy C, Fritchie K, Prat A, Harrell JC, Ewend MG, Carey LA, Miller CR, Anders CK
• PDEF in prostate cancer.
  The Prostate 2011 Sood AK, Kim H, Geradts J
• Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
  Oncogene 2011 Cao X, Geradts J, Dewhirst MW, Lo HW
• Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ.
  Human pathology 2011 West D, Geradts J, Wahidi M, Roggli V
• The genomic relationship between primary breast carcinomas and their nodal metastases.
  Cancer investigation 2011 Desouki MM, Liao S, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J
• Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas.
  Human pathology 2011 Geradts J, de Herreros AG, Su Z, Burchette J, Broadwater G, Bachelder RE
• Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011 Pilie PG, Ibarra-Drendall C, Troch MM, Broadwater G, Barry WT, Petricoin EF, Wulfkuhle JD, Liotta LA, Lem S, Baker JC, Stouder A, Ford AC, Wilke LG, Zalles CM, Mehta P, Williams J, Shivraj M, Su Z, …
• Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2010 O'Brien KM, Cole SR, Tse CK, Perou CM, Carey LA, Foulkes WD, Dressler LG, Geradts J, Millikan RC
• Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast.
  Breast cancer research : BCR 2010 Kennedy S, Geradts J, Bydlon T, Brown JQ, Gallagher J, Junker M, Barry W, Ramanujam N, Wilke L
• The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features.
  Cancer investigation 2010 Geradts J, Bean SM, Bentley RC, Barry WT
• Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach.
  Journal of cancer research and clinical oncology 2010 Desouki MM, Liao S, Huang H, Conroy J, Nowak NJ, Shepherd L, Gaile DP, Geradts J
• Histiocytoid carcinoma of the male breast.
  Annals of diagnostic pathology 2010 Hutchinson CB, Geradts J
• Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins.
  Optics express 2010 Bydlon TM, Kennedy SA, Richards LM, Brown JQ, Yu B, Junker MK, Gallagher J, Geradts J, Wilke LG, Ramanujam N
• Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 Barry WT, Kernagis DN, Dressman HK, Griffis RJ, Hunter JD, Olson JA, Marks JR, Ginsburg GS, Marcom PK, Nevins JR, Geradts J, Datto MB
• Optical assessment of tumor resection margins in the breast.
  IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 2010 Brown JQ, Bydlon TM, Richards LM, Yu B, Kennedy SA, Geradts J, Wilke LG, Junker M, Gallagher J, Barry W, Ramanujam N
• Rapid noninvasive optical imaging of tissue composition in breast tumor margins.
  American journal of surgery 2009 Wilke LG, Brown JQ, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Geradts J, Ramanujam N
• Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009 Sood AK, Wang J, Mhawech-Fauceglia P, Jana B, Liang P, Geradts J
• Re: KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer (Int J Cancer 123: 2239-2246, 2008).
  International journal of cancer 2009 Geradts J
• Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo.
  Cancer research 2009 Brown JQ, Wilke LG, Geradts J, Kennedy SA, Palmer GM, Ramanujam N
• Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2009 Ramanujam N, Brown J, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Wilke LG, Geradts J
• Co-expression of urokinase with haptoglobin in human carcinomas.
  The Journal of surgical research 2008 Harvey S, Kohga S, Sait SN, Markus G, Hurd TC, Martinick M, Geradts J, Saxena R, Gibbs JF
• Epidemiology of basal-like breast cancer.
  Breast cancer research and treatment 2007 Millikan RC, Newman B, Tse CK, Moorman PG, Conway K, Dressler LG, Smith LV, Labbok MH, Geradts J, Bensen JT, Jackson S, Nyante S, Livasy C, Carey L, Earp HS, Perou CM
• hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands.
  Molecular cancer 2007 Desouki MM, Geradts J, Milon B, Franklin RB, Costello LC
• Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression.
  Human pathology 2007 Sood AK, Saxena R, Groth J, Desouki MM, Cheewakriangkrai C, Rodabaugh KJ, Kasyapa CS, Geradts J
• The tetraspanin superfamily member NET-6 is a new tumor suppressor gene.
  Journal of cancer research and clinical oncology 2007 Huang H, Sossey-Alaoui K, Beachy SH, Geradts J
• Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
  Breast cancer research and treatment 2007 Heller G, Geradts J, Ziegler B, Newsham I, Filipits M, Markis-Ritzinger EM, Kandioler D, Berger W, Stiglbauer W, Depisch D, Pirker R, Zielinski CC, Zöchbauer-Müller S
• Akt expression may predict favorable prognosis in cholangiocarcinoma.
  Journal of gastroenterology and hepatology 2006 Javle MM, Yu J, Khoury T, Chadha KS, Chadha KC, Iyer RV, Foster J, Kuvshinoff BW, Gibbs JF, Geradts J, Black JD, Brattain MG
• Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer.
  BMC cancer 2006 Yang J, Ramnath N, Moysich KB, Asch HL, Swede H, Alrawi SJ, Huberman J, Geradts J, Brooks JS, Tan D
• Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.
  JAMA 2006 Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S, Deming SL, Geradts J, Cheang MC, Nielsen TO, Moorman PG, Earp HS, Millikan RC
• Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.
  American journal of clinical oncology 2005 Watwe V, Javle M, Lawrence D, Groth J, Iyer R, El-Hajjar D, Geradts J
• An unusual cause of cholecystitis?
  American journal of clinical oncology 2005 Bush E, Geradts J, O'Connor T
• High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 Lark AL, Livasy CA, Dressler L, Moore DT, Millikan RC, Geradts J, Iacocca M, Cowan D, Little D, Craven RJ, Cance W
• Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York.
  British journal of cancer 2005 Varma G, Varma R, Huang H, Pryshchepava A, Groth J, Fleming D, Nowak NJ, McQuaid D, Conroy J, Mahoney M, Moysich K, Falkner KL, Geradts J
• Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation.
  Oncogene 2005 Zöchbauer-Müller S, Fong KM, Geradts J, Xu X, Seidl S, End-Pfützenreuter A, Lang G, Heller G, Zielinski CC, Gazdar AF, Minna JD
• The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study.
  Breast cancer research : BCR 2005 Conway K, Parrish E, Edmiston SN, Tolbert D, Tse CK, Geradts J, Livasy CA, Singh H, Newman B, Millikan RC
• Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis.
  Gene 2005 Singh KK, Kulawiec M, Still I, Desouki MM, Geradts J, Matsui S
• Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Huang H, Groth J, Sossey-Alaoui K, Hawthorn L, Beall S, Geradts J
• Molecular prediction of recurrence of breast cancer.
  The New England journal of medicine 2005 Geradts J
• Prognostic significance of gelsolin expression level and variability in non-small cell lung cancer.
  Lung cancer (Amsterdam, Netherlands) 2004 Yang J, Tan D, Asch HL, Swede H, Bepler G, Geradts J, Moysich KB
• Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma.
  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004 Wilkinson NW, Black JD, Roukhadze E, Driscoll D, Smiley S, Hoshi H, Geradts J, Javle M, Brattain M
• Microtome shaving radiography: demonstration of loss of mammographic microcalcifications during histologic sectioning.
  The breast journal 2004 Winston JS, Geradts J, Liu DF, Stomper PC
• Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Maitra A, Hansel DE, Argani P, Ashfaq R, Rahman A, Naji A, Deng S, Geradts J, Hawthorne L, House MG, Yeo CJ
• Mammographic predictors of the presence and size of invasive carcinomas associated with malignant microcalcification lesions without a mass.
  AJR. American journal of roentgenology 2003 Stomper PC, Geradts J, Edge SB, Levine EG
• p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.
  The American journal of surgical pathology 2003 Rosty C, Geradts J, Sato N, Wilentz RE, Roberts H, Sohn T, Cameron JL, Yeo CJ, Hruban RH, Goggins M
• Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States).
  Cancer causes & control : CCC 2003 Furberg H, Millikan RC, Geradts J, Gammon MD, Dressler LG, Ambrosone CB, Newman B
• Identification of novel cellular targets in biliary tract cancers using global gene expression technology.
  The American journal of pathology 2003 Hansel DE, Rahman A, Hidalgo M, Thuluvath PJ, Lillemoe KD, Schulick R, Ku JL, Park JG, Miyazaki K, Ashfaq R, Wistuba II, Varma R, Hawthorne L, Geradts J, Argani P, Maitra A
• HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites.
  Breast cancer research and treatment 2003 Millikan R, Eaton A, Worley K, Biscocho L, Hodgson E, Huang WY, Geradts J, Iacocca M, Cowan D, Conway K, Dressler L
• Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003 Parwani AV, Geradts J, Caspers E, Offerhaus GJ, Yeo CJ, Cameron JL, Klimstra DS, Maitra A, Hruban RH, Argani P
• Carcinoma of the esophagus with mixed basaloid squamous and glandular differentiation: a distinct histological presentation.
  International journal of gastrointestinal cancer 2003 Bhagat V, Javle M, Geradts J
• CDKN2A promoter methylation in gastric adenocarcinomas: clinical variables.
  Human pathology 2002 Vo QN, Geradts J, Boudreau DA, Bravo JC, Schneider BG
• Environmental factors in relation to breast cancer characterized by p53 protein expression.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002 Furberg H, Millikan RC, Geradts J, Gammon MD, Dressler LG, Ambrosone CB, Newman B
• Prevalence and spectrum of p53 mutations associated with smoking in breast cancer.
  Cancer research 2002 Conway K, Edmiston SN, Cui L, Drouin SS, Pang J, He M, Tse CK, Geradts J, Dressler L, Liu ET, Millikan R, Newman B
• Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns.
  The Journal of pathology 2001 Boecker W, Buerger H, Schmitz K, Ellis IA, van Diest PJ, Sinn HP, Geradts J, Diallo R, Poremba C, Herbst H
• Immunohistochemical [corrected] detection of the alternate INK4a-encoded tumor suppressor protein p14(ARF) in archival human cancers and cell lines using commercial antibodies: correlation with p16(INK4a) expression.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001 Geradts J, Wilentz RE, Roberts H
• 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
  Cancer research 2001 Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD
• Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas.
  International journal of cancer 2001 Maitra A, Roberts H, Weinberg AG, Geradts J
• Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia.
  Cancer detection and prevention 2001 Creager AJ, Cohen JA, Geradts J
• Abnormal expression of cell cycle regulatory proteins in ductal and lobular carcinomas of the breast.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000 Geradts J, Ingram CD
• Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome.
  Genes, chromosomes & cancer 2000 Wistuba II, Tomlinson GE, Behrens C, Virmani A, Geradts J, Blum JL, Minna JD, Gazdar AF
• p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
  Gynecologic oncology 2000 Schmitz MJ, Hendricks DT, Farley J, Taylor RR, Geradts J, Rose GS, Birrer MJ
• Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas.
  Genes, chromosomes & cancer 2000 Hilgers W, Groot Koerkamp B, Geradts J, Tang DJ, Yeo CJ, Hruban RH, Kern SE
• Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography.
  Radiology 2000 Pisano ED, Johnston RE, Chapman D, Geradts J, Iacocca MV, Livasy CA, Washburn DB, Sayers DE, Zhong Z, Kiss MZ, Thomlinson WC
• Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies.
  Applied immunohistochemistry & molecular morphology : AIMM 2000 Geradts J, Hruban RH, Schutte M, Kern SE, Maynard R
• Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features.
  British journal of cancer 2000 Geradts J, Fong KM, Zimmerman PV, Minna JD
• Loss of p16/CDKN2A tumor suppressor protein in gastric adenocarcinoma is associated with Epstein-Barr virus and anatomic location in the body of the stomach.
  Human pathology 2000 Schneider BG, Gulley ML, Eagan P, Bravo JC, Mera R, Geradts J
• Estrogen receptor status, determined by immunohistochemistry, as a predictor of the recurrence of stage I endometrial carcinoma.
  Cancer 1999 Gehrig PA, Van Le L, Olatidoye B, Geradts J
• Loss of KAI1 expression in the progression of colorectal cancer.
  Cancer research 1999 Lombardi DP, Geradts J, Foley JF, Chiao C, Lamb PW, Barrett JC
• Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. University of North Carolina Specialized Program of Research Excellence.
  Breast cancer research and treatment 1999 Dressler LG, Geradts J, Burroughs M, Cowan D, Millikan RC, Newman B
• Abnormal Fhit expression in malignant and premalignant lesions of the cervix.
  Cancer research 1999 Birrer MJ, Hendricks D, Farley J, Sundborg MJ, Bonome T, Walts MJ, Geradts J
• Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
  The American journal of pathology 1999 Geradts J, Maynard R, Birrer MJ, Hendricks D, Abbondanzo SL, Fong KM, Barrett JC, Lombardi DP
• G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder.
  British journal of cancer 1999 Niehans GA, Kratzke RA, Froberg MK, Aeppli DM, Nguyen PL, Geradts J
• The 100-kDa proteolytic fragment of RB is retained predominantly within the nuclear compartment of apoptotic cells.
  Molecular cell biology research communications : MCBRC 1999 Chen WD, Geradts J, Keane MM, Lipkowitz S, Zajac-Kaye M, Kaye FJ
• Correlation of abnormal RB, p16ink4a, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers.
  Clinical cancer research : an official journal of the American Association for Cancer Research 1999 Geradts J, Fong KM, Zimmerman PV, Maynard R, Minna JD
• Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression.
  Cancer research 1998 Wilentz RE, Geradts J, Maynard R, Offerhaus GJ, Kang M, Goggins M, Yeo CJ, Kern SE, Hruban RH
• RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer.
  Oncogene 1998 Coxon AB, Ward JM, Geradts J, Otterson GA, Zajac-Kaye M, Kaye FJ
• Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression.
  Oncogene 1998 Frizelle SP, Grim J, Zhou J, Gupta P, Curiel DT, Geradts J, Kratzke RA
• Loss of tumor suppressor gene expression in high-grade but not low-grade non-Hodgkin's lymphomas.
  American journal of clinical pathology 1998 Geradts J, Andriko JW, Abbondanzo SL
• Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product.
  The American journal of pathology 1998 Gulley ML, Nicholls JM, Schneider BG, Amin MB, Ro JY, Geradts J
• Protein expression and functional analysis of the FHIT gene in human tumor cells.
  Journal of the National Cancer Institute 1998 Otterson GA, Xiao GH, Geradts J, Jin F, Chen WD, Niklinska W, Kaye FJ, Yeung RS
• Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.
  Cancer research 1997 Schutte M, Hruban RH, Geradts J, Maynard R, Hilgers W, Rabindran SK, Moskaluk CA, Hahn SA, Schwarte-Waldhoff I, Schmiegel W, Baylin SB, Kern SE, Herman JG
• Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas.
  Human pathology 1997 Cohen JA, Geradts J
• Molecular characterization of adenocarcinoma of the cervix.
  Gynecologic oncology 1997 Parker MF, Arroyo GF, Geradts J, Sabichi AL, Park RC, Taylor RR, Birrer MJ
• Rb and p16INK4a expression in resected non-small cell lung tumors.
  Cancer research 1996 Kratzke RA, Greatens TM, Rubins JB, Maddaus MA, Niewoehner DE, Niehans GA, Geradts J
• High frequency of aberrant p16(INK4A) expression in human breast cancer.
  The American journal of pathology 1996 Geradts J, Wilson PA
• Wild-type and mutant retinoblastoma protein in paraffin sections.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1996 Geradts J, Kratzke RA, Crush-Stanton S, Wen SF, Lincoln CE
• Molecular and immunochemical analyses of RB1 and cyclin D1 in human ductal pancreatic carcinomas and cell lines.
  Molecular carcinogenesis 1996 Huang L, Lang D, Geradts J, Obara T, Klein-Szanto AJ, Lynch HT, Ruggeri BA
• Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma.
  Journal of the National Cancer Institute 1995 Kratzke RA, Otterson GA, Lincoln CE, Ewing S, Oie H, Geradts J, Kaye FJ
• Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression.
  Cancer research 1995 Geradts J, Kratzke RA, Niehans GA, Lincoln CE
• The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology.
  Breast cancer research and treatment 1995 Newman B, Moorman PG, Millikan R, Qaqish BF, Geradts J, Aldrich TE, Liu ET
• The need for epidemiologic studies of in-situ carcinoma of the breast.
  Breast cancer research and treatment 1995 Millikan R, Dressler L, Geradts J, Graham M
• Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies.
  International journal of cancer 1994 Geradts J, Hu SX, Lincoln CE, Benedict WF, Xu HJ
• Pathology and laboratory medicine.
  JAMA 1994 Geradts J, McLendon WW
• Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.
  Oncogene 1994 Kratzke RA, Otterson GA, Hogg A, Coxon AB, Geradts J, Cowell JK, Kaye FJ
• Retinoblastoma protein monoclonal antibodies with novel characteristics.
  Journal of immunological methods 1994 Wen SF, Nodelman M, Nared-Hood K, Duncan J, Geradts J, Shepard HM
• Human lung cancer cell lines exhibit resistance to retinoic acid treatment.
  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993 Geradts J, Chen JY, Russell EK, Yankaskas JR, Nieves L, Minna JD
• RB-mediated tumor suppression of a lung cancer cell line is abrogated by an extract enriched in extracellular matrix.
  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993 Kratzke RA, Shimizu E, Geradts J, Gerster JL, Segal S, Otterson GA, Kaye FJ
• Use of the polymerase chain reaction in the diagnosis of unsuspected herpes simplex viral pneumonia: report of a case.
  Human pathology 1990 Geradts J, Warnock M, Yen TS
• Second international workshop on monoclonal antibodies and breast cancer. San Francisco, November 20-21, 1986.
  Breast cancer research and treatment 1987 Ceriani RL, Geradts J, Peterson JA
• Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor.
  Cancer research 1986 Geradts J, Richards J, Edery M, Pang K, Larson L, Nandi S