Joseph Cuschieri, MD, FACS
Professor
Surgery
School of Medicine

Upon completion of his clinical training, he completed a 2-year NIH T32 Fellowship in the field of Trauma/Burn/Inflammation.

Dr. Cuschieri is certified by the American Board of Surgery in General Surgery with subspecialty certification in Surgical Critical Care.

Upon completion of his fellowship in 2002, Dr. Cuschieri joined the faculty at the University of Cincinnati School of Medicine. After a couple of years he left Cincinnati and returned to Seattle, joining the faculty at the University of Washington School of Medicine where he served as the Medical Director of Surgical Critical Care, Interim Associate Medical Director of Critical Care, Associate Medical Director of Surgical Services, and Program Director of Surgical Critical Care. Dr. Cuschieri left Washington and came to UCSF in 2021 to join the faculty in the Department of Surgery as Professor and Trauma Medical Director at the Zuckerberg San Francisco General Hospital and Trauma Center.

Dr. Cuschieri currently serves as Principal Investigator, Co-Principle investigator, or Co-Investigator on 3 federally funded grants and has authored or co-authored over 170 peer-reviewed articles and more than 10 book chapters. His national service includes active participation in major trauma, critical care, and surgical societies including the American Association for the Surgery of Trauma and the Society of Surgical Critical Care Program Directors. He also serves on the Editorial Board for the Journal of Trauma and Acute Care Surgery.

• Surgical and procedural antibiotic prophylaxis in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.
  Trauma surgery & acute care open 2024 Farrell MS, Agapian JV, Appelbaum RD, Filiberto DM, Gelbard R, Hoth J, Jawa R, Kirsch J, Kutcher ME, Nohra E, Pathak A, Paul J, Robinson B, Cuschieri J, Stein DM
• Scanning the aged to minimize missed injury: An EAST multicenter study.
  The journal of trauma and acute care surgery 2024 Ho VP, Kishawi SK, Hill H, O'Brien J, Ratnasekera A, Seng SS, Ton TH, Butts CA, Muller A, Diaz BF, Baltazar GA, Petrone P, Pacheco TBS, Morrissey S, Chung T, Biller J, Jacobson LE, Williams JM, …
• Balanced resuscitation: the role during non-massive hemorrhage.
  Trauma surgery & acute care open 2024 Garber K, Kornblith L, Cuschieri J
• Early Cold Stored Platelet Transfusion Following Severe Injury: A Randomized Clinical Trial.
  Annals of surgery 2024 Sperry JL, Guyette FX, Rosario-Rivera BL, Kutcher ME, Kornblith LZ, Cotton BA, Wilson CT, Inaba K, Zadorozny EV, Vincent LE, Harner AM, Love ET, Doherty JE, Cuschieri J, Kornblith AE, Fox EE, Bai Y, …
• Regulation of Vascular Endothelial Integrity by Mesenchymal Stem Cell Extracellular Vesicles after Hemorrhagic Shock and Trauma.
  Research square 2024 Barry M, Trivedi A, Miyazawa B, Vivona L, Shimmin D, Pathipati P, Keane C, Cuschieri J, Pati S
• Insights from CTTACC: immune system reset by cellular therapies for chronic illness after trauma, infection, and burn.
  Cytotherapy 2024 Bertram K, Cox C, Alam H, Lowell C, Cuschieri J, Parekkadan B, Pati S
• Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial.
  The Journal of bone and joint surgery. American volume 2024 O'Hara NN, Frey KP, Stein DM, Levy JF, Slobogean GP, Castillo R, Firoozabadi R, Karunakar MA, Gary JL, Obremskey WT, Seymour RB, Cuschieri J, Mullins CD, O'Toole RV, METRC
• Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopedic trauma patients: A secondary analysis of the PREVENT CLOT trial.
  The journal of trauma and acute care surgery 2023 O'Hara NN, O'Toole RV, Frey KP, Castillo RC, Cuschieri J, Haut ER, Slobogean GP, Firoozabadi R, Christmas AB, Obremskey WT, Carlini AR, Gaski GE, Kutcher ME, Marvel D, Stein DM, Major Extremity Trauma…
• Screening for Intimate Partner Violence in Trauma: Results of a Quality Improvement Project.
  The Journal of surgical research 2023 Decker H, Schwab M, Shao S, Kaki D, Melhado C, Cuschieri J, Bongiovanni T
• The injured monocyte: The link to chronic critical illness and mortality following injury.
  The journal of trauma and acute care surgery 2023 Cuschieri J, Kornblith L, Pati S, Piliponsky A
• Trial Participation and Outcomes Among English-Speaking and Spanish-Speaking Patients With Appendicitis Randomized to Antibiotics: A Secondary Analysis of the CODA Randomized Clinical Trial.
  JAMA surgery 2023 Serrano E, Voldal EC, Machado-Aranda D, DeUgarte DA, Kao L, Drake T, Winchell R, Cuschieri J, Krishnadasan A, Talan DA, Siparsky N, Ayoung-Chee P, Self WH, McGonagill P, Mandell KA, Liang MK, Dodwad …
• Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.
  Trauma surgery & acute care open 2023 Seshadri A, Cuschieri J, Kaups KL, Knowlton LM, Kutcher ME, Pathak A, Rappold J, Rinderknecht T, Stein DM, Young J, Michetti CP
• Developing a National Trauma Research Action Plan: Results from the long-term outcomes research gap Delphi survey.
  The journal of trauma and acute care surgery 2022 Herrera-Escobar JP, Reidy E, Phuong J, Brasel KJ, Cuschieri J, Fallat M, Potter BK, Price MA, Bulger EM, Haider AH, Bonne S, Brasel KJ, Cuschieri J, de Roon-Cassini T, Dicker RA, Fallat M, Ficke JR, …
• Alcohol Intoxication Is Associated With Bladder Injury and Bladder Surgical Repair in Patients Sustaining Motor Vehicle Collisions.
  The Journal of urology 2022 Lui JL, Hakam N, Shaw NM, Cuschieri J, Abbasi B, Breyer BN
• Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.
  Trauma surgery & acute care open 2022 Seshadri A, Appelbaum R, Carmichael SP, Cuschieri J, Hoth J, Kaups KL, Kodadek L, Kutcher ME, Pathak A, Rappold J, Rudnick SR, Michetti CP
• Perception of Treatment Success and Impact on Function with Antibiotics or Appendectomy for Appendicitis: A Randomized Clinical Trial with an Observational Cohort.
  Annals of surgery 2022 Thompson CM, Voldal EC, Davidson GH, Sanchez SE, Ayoung-Chee P, Victory J, Guiden M, Bizzell B, Glaser J, Hults C, Price TP, Siparsky N, Ohe K, Mandell KA, DeUgarte DA, Kaji AH, Uribe L, Kao LS, Mueck…
• Analysis of Outcomes Associated With Outpatient Management of Nonoperatively Treated Patients With Appendicitis.
  JAMA network open 2022 Writing Group for the CODA Collaborative, Talan DA, Moran GJ, Krishnadasan A, Monsell SE, Faine BA, Uribe L, Kaji AH, DeUgarte DA, Self WH, Shapiro NI, Cuschieri J, Glaser J, Park PK, Price TP, …
• Self-selection vs Randomized Assignment of Treatment for Appendicitis.
  JAMA surgery 2022 Writing Group for the CODA Collaborative, Davidson GH, Monsell SE, Evans H, Voldal EC, Fannon E, Lawrence SO, Krishnadasan A, Talan DA, Bizzell B, Heagerty PJ, Comstock BA, Lavallee DC, Villegas C, …
• Postinjury platelet aggregation and venous thromboembolism.
  The journal of trauma and acute care surgery 2022 Matthay ZA, Hellmann ZJ, Nunez-Garcia B, Fields AT, Cuschieri J, Neal MD, Berger JS, Luttrell-Williams E, Knudson MM, Cohen MJ, Callcut RA, Kornblith LZ
• Developing a National Trauma Research Action Plan: Results from the acute resuscitation, initial patient evaluation, imaging, and management research gap Delphi survey.
  The journal of trauma and acute care surgery 2022 Costantini TW, Galante JM, Braverman MA, Phuong J, Price MA, Cuschieri J, Godat LN, Holcomb JB, Coimbra R, Bulger EM, NTRAP Acute Resuscitation Panel
• Nonoperative Management in Blunt Splenic Trauma: Can Shock Index Predict Failure?
  The Journal of surgical research 2022 Senekjian L, Robinson BRH, Meagher AD, Gross JA, Maier RV, Bulger EM, Arbabi S, Cuschieri J
• Patient Factors Associated With Appendectomy Within 30 Days of Initiating Antibiotic Treatment for Appendicitis.
  JAMA surgery 2022 Writing Group for the CODA Collaborative, Monsell SE, Voldal EC, Davidson GH, Fischkoff K, Coleman N, Bizzell B, Price T, Narayan M, Siparsky N, Thompson CM, Ayoung-Chee P, Odom SR, Sanchez S, Drake …
• A new trauma frontier: Exploratory pilot study of platelet transcriptomics in trauma patients.
  The journal of trauma and acute care surgery 2022 Fields AT, Lee MC, Mayer F, Santos YA, Bainton CMV, Matthay ZA, Callcut RA, Mayer N, Cuschieri J, Kober KM, Bainton RJ, Kornblith LZ
• Utility and Outcome of Angioembolization for High-Grade Renal Trauma Management in a Large Hospital-Based Trauma Registry.
  The Journal of urology 2022 Hakam N, Amend GM, Nabavizadeh B, Allen IE, Shaw NM, Cuschieri J, Wilson MW, Stein DM, Breyer BN
• Respiratory events after intensive care unit discharge in trauma patients: Epidemiology, outcomes, and risk factors.
  The journal of trauma and acute care surgery 2022 Rosen JE, Bulger EM, Cuschieri J
• Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.
  The British journal of surgery 2021 COVIDSurg Collaborative
• Antibiotics versus Appendectomy for Acute Appendicitis - Longer-Term Outcomes.
  The New England journal of medicine 2021 CODA Collaborative, Davidson GH, Flum DR, Monsell SE, Kao LS, Voldal EC, Heagerty PJ, Fannon E, Lavallee DC, Bizzell B, Lawrence SO, Comstock BA, Krishnadasan A, Winchell RJ, Self WH, Thompson CM, …
• Chronic critical illness after hypothermia in trauma patients.
  Trauma surgery & acute care open 2021 Miranda D, Maine R, Cook M, Brakenridge S, Moldawer L, Arbabi S, O'Keefe G, Robinson B, Bulger EM, Maier R, Cuschieri J
• Multi-center validation of the Bowel Injury Predictive Score (BIPS) for the early identification of need to operate in blunt bowel and mesenteric injuries.
  Injury 2021 Wandling M, Cuschieri J, Kozar R, O'Meara L, Celii A, Starr W, Burlew CC, Todd SR, de Leon A, McIntyre RC, Urban S, Biffl WL, Bayat D, Dunn J, Peck K, Rooney AS, Kornblith LZ, Callcut RA, Lollar DI, …
• The Covid-19 Pandemic: Lessons Learned for Sustained Trauma Preparedness and Responses.
  Annals of surgery 2021 Cuschieri J, Robinson B, Lynch J, Mitchell S, Arbabi S, Bryson C, Sayre M, Maier RV, Bulger E
• Aspirin versus anticoagulation for stroke prophylaxis in blunt cerebrovascular injury: a propensity-matched retrospective cohort study.
  Journal of neurosurgery 2021 Bonow RH, Witt CE, Mossa-Basha M, Cuschieri J, Arbabi S, Vavilala MS, Rivara FP, Chesnut RM
• PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients.
  BMJ open 2021 O'Toole RV, Stein DM, Frey KP, O'Hara NN, Scharfstein DO, Slobogean GP, Taylor TJ, Haac BE, Carlini AR, Manson TT, Sudini K, Mullins CD, Wegener ST, Firoozabadi R, Haut ER, Bosse MJ, Seymour RB, …
• Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.
  Trauma surgery & acute care open 2021 Rappold JF, Sheppard FR, Carmichael Ii SP, Cuschieri J, Ley E, Rangel E, Seshadri AJ, Michetti CP
• Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock.
  The journal of trauma and acute care surgery 2021 Brakenridge SC, Wang Z, Cox M, Raymond S, Hawkins R, Darden D, Ghita G, Brumback B, Cuschieri J, Maier RV, Moore FA, Mohr AM, Efron PA, Moldawer LL
• Persistent metabolomic alterations characterize chronic critical illness after severe trauma.
  The journal of trauma and acute care surgery 2021 Horn DL, Bettcher LF, Navarro SL, Pascua V, Neto FC, Cuschieri J, Raftery D, O'Keefe GE
• Changes in error patterns in unanticipated trauma deaths during 20 years: In pursuit of zero preventable deaths.
  The journal of trauma and acute care surgery 2020 LaGrone LN, McIntyre L, Riggle A, Robinson BRH, Maier RV, Bulger E, Cuschieri J
• A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis.
  The New England journal of medicine 2020 CODA Collaborative, Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, …
• Society of Interventional Radiology Clinical Practice Guideline for Inferior Vena Cava Filters in the Treatment of Patients with Venous Thromboembolic Disease: Developed in collaboration with the American College of Cardiology, American College of Chest Physicians, American College of Surgeons Committee on Trauma, American Heart Association, Society for Vascular Surgery, and Society for Vascular Medicine.
  Journal of vascular and interventional radiology : JVIR 2020 Kaufman JA, Barnes GD, Chaer RA, Cuschieri J, Eberhardt RT, Johnson MS, Kuo WT, Murin S, Patel S, Rajasekhar A, Weinberg I, Gillespie DL
• Authors' reply: Understanding state-level Medicaid expansion in the context of nationwide data.
  The journal of trauma and acute care surgery 2020 Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH
• Splenic artery angioembolization for high-grade splenic injury: Are we wasting money?
  American journal of surgery 2020 Senekjian L, Cuschieri J, Robinson BRH
• Predictors of mortality, limb loss, and discharge disposition at admission among patients with necrotizing skin and soft tissue infections.
  The journal of trauma and acute care surgery 2020 Horn DL, Shen J, Roberts E, Wang TN, Li KS, O'Keefe GE, Cuschieri J, Bulger EM, Robinson BRH
• Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.
  Lancet (London, England) 2020 COVIDSurg Collaborative
• Prospective Validation of a Transcriptomic Metric in Severe Trauma.
  Annals of surgery 2020 Raymond SL, Hawkins RB, Wang Z, Mira JC, Stortz JA, Han F, Lanz JD, Hennessy LV, Brumback BA, Baker HV, Efron PA, Brakenridge SC, Xiao W, Tompkins RG, Cuschieri J, Moore FA, Maier RV, Moldawer LL
• Proceedings from the Consensus Conference on Trauma Patient-Reported Outcome Measures.
  Journal of the American College of Surgeons 2020 Sakran JV, Ezzeddine H, Schwab CW, Bonne S, Brasel KJ, Burd RS, Cuschieri J, Ficke J, Gaines BA, Giacino JT, Gibran NS, Haider A, Hall EC, Herrera-Escobar JP, Joseph B, Kao L, Kurowski BG, Livingston …
• Contemporary hemodynamic monitoring, fluid responsiveness, volume optimization, and endpoints of resuscitation: an AAST critical care committee clinical consensus.
  Trauma surgery & acute care open 2020 Martin ND, Codner P, Greene W, Brasel K, Michetti C, AAST Critical Care Committee
• Lifting the burden: State Medicaid expansion reduces financial risk for the injured.
  The journal of trauma and acute care surgery 2020 Scott JW, Shrime MG, Stewart BT, Arbabi S, Bulger EM, Cuschieri J, Maier RV, Robinson BRH
• Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma.
  Scientific reports 2019 Stortz JA, Hawkins RB, Holden DC, Raymond SL, Wang Z, Brakenridge SC, Cuschieri J, Moore FA, Maier RV, Moldawer LL, Efron PA
• Ventilator-associated events, not ventilator-associated pneumonia, is associated with higher mortality in trauma patients.
  The journal of trauma and acute care surgery 2019 Meagher AD, Lind M, Senekjian L, Iwuchukwu C, Lynch JB, Cuschieri J, Robinson BRH
• Authors Response to Commentary on our Manuscript.
  The journal of trauma and acute care surgery 2019 Cook MR, Cuschieri J
• Trauma Surgeon and Palliative Care Physician Attitudes Regarding Goals-of-Care Delineation for Injured Geriatric Patients.
  The American journal of hospice & palliative care 2019 Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan …
• Burn Surgeon and Palliative Care Physician Attitudes Regarding Goals of Care Delineation for Burned Geriatric Patients.
  Journal of burn care & research : official publication of the American Burn Association 2018 Cunningham HB, Scielzo SA, Nakonezny PA, Bruns BR, Brasel KJ, Inaba K, Brakenridge SC, Kerby JD, Joseph BA, Mohler MJ, Cuschieri J, Paulk ME, Ekeh AP, Madni TD, Taveras LR, Imran JB, Wolf SE, Phelan …
• Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures.
  Annals of surgery 2018 O'Connell KM, Quistberg DA, Tessler R, Robinson BRH, Cuschieri J, Maier RV, Rivara FP, Vavilala MS, Bhalla PI, Arbabi S
• Unique Uses of Cooling Strategies.
  Therapeutic hypothermia and temperature management 2018 Lyden P, Paul J, Yokobori S, Cuschieri J
• Duration of Respiratory Failure After Trauma Is Not Associated With Increased Long-Term Mortality.
  Critical care medicine 2018 Cook MR, O'Connell K, Qiu Q, Riggle AJ, Shoultz TH, Maine RG, Arbabi S, O'Keefe GE, Cuschieri J, Maier RV, Robinson BRH
• Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial.
  JAMA surgery 2018 Parent B, LaGrone LN, Albirair MT, Serina PT, Keller JM, Cuschieri J, Addison EJ, Choe L, Delossantos GB, Gaskill CE, Moon SD, MacDonald JT, Stolzberg MJ, Van Eaton EG, Zech JM, Kritek PA
• Fellowship training in extracorporeal life support: Characterization and educational needs assessment.
  Journal of critical care 2018 Cook MR, Badulak J, Çoruh B, Kiraly LN, Zonies D, Cuschieri J, Bulger EM
• Short-Course Antimicrobial Therapy Does Not Increase Treatment Failure Rate in Patients with Intra-Abdominal Infection Involving Fungal Organisms.
  Surgical infections 2018 Elwood NR, Guidry CA, Duane TM, Cuschieri J, Cook CH, O'Neill PJ, Askari R, Napolitano LM, Namias N, Dellinger EP, Watson CM, Banton KL, Blake DP, Hassinger TE, Sawyer RG
• A cohort study of blunt cerebrovascular injury screening in children: Are they just little adults?
  The journal of trauma and acute care surgery 2018 Cook MR, Witt CE, Bonow RH, Bulger EM, Linnau KF, Arbabi S, Robinson BRH, Cuschieri J
• The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.
  Critical care medicine 2017 Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC
• Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Celestin AR, Odom SR, Angelidou K, Evans SR, Coimbra R, Guidry CA, Cuschieri J, Banton KL, O'Neill PJ, Askari R, Namias N, Duane TM, Claridge JA, Dellinger EP, Sawyer RA, Cook CH
• Does Isolation of Enterococcus Affect Outcomes in Intra-Abdominal Infections?
  Surgical infections 2017 Sanders JM, Tessier JM, Sawyer R, Dellinger EP, Miller PR, Namias N, West MA, Cook CH, O'Neill PJ, Napolitano L, Rattan R, Cuschieri J, Claridge JA, Guidry CA, Askari R, Banton K, Rotstein O, Moore BJ…
• Transcranial Doppler Microemboli Monitoring for Stroke Risk Stratification in Blunt Cerebrovascular Injury.
  Critical care medicine 2017 Bonow RH, Witt CE, Mosher BP, Mossa-Basha M, Vavilala MS, Rivara FP, Cuschieri J, Arbabi S, Chesnut RM
• Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial.
  JAMA 2017 Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink …
• Validation of a Geriatric Trauma Prognosis Calculator: A P.A.L.Li.A.T.E. Consortium Study.
  Journal of the American Geriatrics Society 2017 Cook AC, Joseph B, Mohler MJ, Inaba K, Bruns BR, Nakonezny PA, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Ekeh AP, Phelan HA
• A comparison of prognosis calculators for geriatric trauma: A Prognostic Assessment of Life and Limitations After Trauma in the Elderly consortium study.
  The journal of trauma and acute care surgery 2017 Madni TD, Ekeh AP, Brakenridge SC, Brasel KJ, Joseph B, Inaba K, Bruns BR, Kerby JD, Cuschieri J, Mohler MJ, Nakonezny PA, Clark A, Imran J, Wolf SE, Paulk ME, Rhodes RL, Phelan HA
• Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections.
  Surgical infections 2017 Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, …
• Age and Its Impact on Outcomes with Intra-Abdominal Infection.
  Surgical infections 2016 Farmer D, Tessier JM, Sanders JM, Sawyer RG, Rotstein OD, Dellinger EP, Lipsett PA, Cuschieri J, Miller P, Cook CH, Guidry CA, Askari R, Moore BJ, Duane TM
• Preventing hospital-acquired venous thromboembolism: Improving patient safety with interdisciplinary teamwork, quality improvement analytics, and data transparency.
  Journal of hospital medicine 2016 Schleyer AM, Robinson E, Dumitru R, Taylor M, Hayes K, Pergamit R, Beingessner DM, Zaros MC, Cuschieri J
• Acute Rehabilitation after Trauma: Does it Really Matter?
  Journal of the American College of Surgeons 2016 Nehra D, Nixon ZA, Lengenfelder C, Bulger EM, Cuschieri J, Maier RV, Arbabi S
• Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection.
  The American surgeon 2016 Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K…
• Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock.
  The journal of trauma and acute care surgery 2016 Lopez MC, Efron PA, Ozrazgat-Baslanti T, Zhang J, Cuschieri J, Maier RV, Minei JP, Baker HV, Moore FA, Moldawer LL, Brakenridge SC
• Inclusion of Vancomycin as Part of Broad-Spectrum Coverage Does Not Improve Outcomes in Patients with Intra-Abdominal Infections: A Post Hoc Analysis.
  Surgical infections 2016 Sanders JM, Tessier JM, Sawyer RG, Lipsett PA, Miller PR, Namias N, O'Neill PJ, Dellinger EP, Coimbra R, Guidry CA, Cuschieri J, Banton KL, Cook CH, Moore BJ, Duane TM
• Surgical Management of Clostridium difficile Infection: The Role of Colectomy.
  Surgical infections 2016 Delano MJ, Cuschieri J
• Multicenter external validation of the Geriatric Trauma Outcome Score: A study by the Prognostic Assessment of Life and Limitations After Trauma in the Elderly (PALLIATE) consortium.
  The journal of trauma and acute care surgery 2016 Cook AC, Joseph B, Inaba K, Nakonezny PA, Bruns BR, Kerby JD, Brasel KJ, Wolf SE, Cuschieri J, Paulk ME, Rhodes RL, Brakenridge SC, Phelan HA
• Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy.
  Journal of the American College of Surgeons 2016 Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein…
• The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion.
  Shock (Augusta, Ga.) 2016 Plevin RE, Knoll M, McKay M, Arbabi S, Cuschieri J
• Pediatric solid organ injury operative interventions and outcomes at Harborview Medical Center, before and after introduction of a solid organ injury pathway for pediatrics.
  The journal of trauma and acute care surgery 2015 Dervan LA, King MA, Cuschieri J, Rivara FP, Weiss NS
• Prehospital Resuscitation of Traumatic Hemorrhagic Shock with Hypertonic Solutions Worsens Hypocoagulation and Hyperfibrinolysis.
  Shock (Augusta, Ga.) 2015 Delano MJ, Rizoli SB, Rhind SG, Cuschieri J, Junger W, Baker AJ, Dubick MA, Hoyt DB, Bulger EM
• Trial of short-course antimicrobial therapy for intraabdominal infection.
  The New England journal of medicine 2015 Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent …
• Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma.
  Annals of surgery 2015 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Morbidity and survival probability in burn patients in modern burn care.
  Critical care medicine 2015 Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN, Inflammation and the Host Response to Injury Collaborative Research Program
• Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock.
  Critical care (London, England) 2015 Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, Leeuwenburgh C, Moore FA, Baker HV, Moldawer LL, Brakenridge SC, Efron PA, Inflammation …
• Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation.
  The journal of trauma and acute care surgery 2015 Kutcher ME, Howard BM, Sperry JL, Hubbard AE, Decker AL, Cuschieri J, Minei JP, Moore EE, Brownstein BH, Maier RV, Cohen MJ
• Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy.
  Annals of surgery 2014 Neal MD, Brown JB, Moore EE, Cuschieri J, Maier RV, Minei JP, Billiar TR, Peitzman AB, Cohen MJ, Sperry JL, Inflammation and Host Response to Injury Investigators
• Pre-hospital aspiration is associated with increased pulmonary complications.
  Surgical infections 2014 Fawcett VJ, Warner KJ, Cuschieri J, Copass M, Grabinsky A, Kwok H, Rea T, Evans HL
• A better understanding of why murine models of trauma do not recapitulate the human syndrome.
  Critical care medicine 2014 Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA
• Benchmarking outcomes in the critically injured burn patient.
  Annals of surgery 2014 Klein MB, Goverman J, Hayden DL, Fagan SP, McDonald-Smith GP, Alexander AK, Gamelli RL, Gibran NS, Finnerty CC, Jeschke MG, Arnoldo B, Wispelwey B, Mindrinos MN, Xiao W, Honari SE, Mason PH, …
• Delayed topical p38 MAPK inhibition attenuates full-thickness burn wound inflammatory signaling.
  Journal of burn care & research : official publication of the American Burn Association 2014 Carter D, Warsen A, Mandell K, Cuschieri J, Maier RV, Arbabi S
• Differences in end-of-life care in the ICU across patients cared for by medicine, surgery, neurology, and neurosurgery physicians.
  Chest 2014 Kross EK, Engelberg RA, Downey L, Cuschieri J, Hallman MR, Longstreth WT, Tirschwell DL, Curtis JR
• Determining a core curriculum in surgical infections for fellowship training in acute care surgery using the Delphi technique.
  Surgical infections 2013 May AK, Cuschieri J, Johnson JL, Duane TM, Cherry-Bukowiec JR, Rosengart MR
• Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study.
  Journal of hospital medicine 2013 Schleyer AM, Jarman KM, Calver P, Cuschieri J, Robinson E, Goss JR
• Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury.
  Shock (Augusta, Ga.) 2013 Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Baker AJ, Shek PN, Hoyt DB, Bulger EM
• Determination of burn patient outcome by large-scale quantitative discovery proteomics.
  Critical care medicine 2013 Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, …
• Trauma-associated human neutrophil alterations revealed by comparative proteomics profiling.
  Proteomics. Clinical applications 2013 Zhou JY, Krovvidi RK, Gao Y, Gao H, Petritis BO, De AK, Miller-Graziano CL, Bankey PE, Petyuk VA, Nicora CD, Clauss TR, Moore RJ, Shi T, Brown JN, Kaushal A, Xiao W, Davis RW, Maier RV, Tompkins RG, …
• Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism?
  The journal of trauma and acute care surgery 2013 Brakenridge SC, Henley SS, Kashner TM, Golden RM, Paik DH, Phelan HA, Cohen MJ, Sperry JL, Moore EE, Minei JP, Maier RV, Cuschieri J, Inflammation and the Host Response to Injury Investigators
• Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients.
  Critical care medicine 2013 Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Baslanti TO, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL, …
• Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis.
  The journal of trauma and acute care surgery 2013 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Genomic responses in mouse models poorly mimic human inflammatory diseases.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, …
• Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients.
  Critical care medicine 2013 Harr JN, Moore EE, Johnson J, Chin TL, Wohlauer MV, Maier R, Cuschieri J, Sperry J, Banerjee A, Silliman CC, Sauaia A
• Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix.
  The journal of trauma and acute care surgery 2012 Brown JB, Cohen MJ, Minei JP, Maier RV, West MA, Billiar TR, Peitzman AB, Moore EE, Cuschieri J, Sperry JL, Inflammation and the Host Response to Injury Investigators
• Who should we feed? Western Trauma Association multi-institutional study of enteral nutrition in the open abdomen after injury.
  The journal of trauma and acute care surgery 2012 Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Nirula R, Millar D, Cohen MJ, Kutcher ME, Haan J, MacNew HG, Ochsner G, Rowell SE, Truitt MS, Moore FO, Pieracci FM, Kaups KL, WTA Study Group
• Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation.
  Shock (Augusta, Ga.) 2012 Junger WG, Rhind SG, Rizoli SB, Cuschieri J, Shiu MY, Baker AJ, Li L, Shek PN, Hoyt DB, Bulger EM
• Acute respiratory distress syndrome after trauma: development and validation of a predictive model.
  Critical care medicine 2012 Watkins TR, Nathens AB, Cooke CR, Psaty BM, Maier RV, Cuschieri J, Rubenfeld GD
• Hypothermia in massive transfusion: have we been paying enough attention to it?
  The journal of trauma and acute care surgery 2012 Reynolds BR, Forsythe RM, Harbrecht BG, Cuschieri J, Minei JP, Maier RV, Moore EE, Billiar EE, Peitzman AB, Sperry JL, Inflammation and Host Response to Injury Investigators
• The role and value of surgical critical care, an essential component of Acute Care Surgery, in the Affordable Care Act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma.
  The journal of trauma and acute care surgery 2012 Frankel HL, Butler KL, Cuschieri J, Friese RS, Huynh T, Mohr AM, Schinco MA, Napolitano LM, Britt LD, Coimbra R, Croce MA, Davis JW, Jurkovich GJ, Moore EE, Morris JA, Peitzman AB, Pruitt BA, Rozycki …
• Active surveillance cultures of methicillin-resistant Staphylococcus aureus as a tool to predict methicillin-resistant S. aureus ventilator-associated pneumonia.
  Critical care medicine 2012 Chan JD, Dellit TH, Choudhuri JA, McNamara E, Melius EJ, Evans HL, Cuschieri J, Arbabi S, Lynch JB
• Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.
  Annals of surgery 2012 Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, …
• Ventilator-associated pneumonia rates at major trauma centers compared with a national benchmark: a multi-institutional study of the AAST.
  The journal of trauma and acute care surgery 2012 Michetti CP, Fakhry SM, Ferguson PL, Cook A, Moore FO, Gross R, AAST Ventilator-Associated Pneumonia Investigators
• Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way.
  The journal of trauma and acute care surgery 2012 Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL
• The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock.
  Critical care medicine 2012 Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• Obese patients show a depressed cytokine profile following severe blunt injury.
  Shock (Augusta, Ga.) 2012 Winfield RD, Delano MJ, Cuenca AG, Cendan JC, Lottenberg L, Efron PA, Maier RV, Remick DG, Moldawer LL, Cuschieri J
• Ventilator-associated pneumonia: bacteremia and death after traumatic injury.
  The journal of trauma and acute care surgery 2012 O'Keefe GE, Caldwell E, Cuschieri J, Wurfel MM, Evans HL
• Changes in massive transfusion over time: an early shift in the right direction?
  The journal of trauma and acute care surgery 2012 Kautza BC, Cohen MJ, Cuschieri J, Minei JP, Brackenridge SC, Maier RV, Harbrecht BG, Moore EE, Billiar TR, Peitzman AB, Sperry JL, Inflammation and the Host Response to Injury Investigators
• A genomic storm in critically injured humans.
  The Journal of experimental medicine 2011 Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker…
• Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients.
  Shock (Augusta, Ga.) 2011 Bulger EM, Tower CM, Warner KJ, Garland T, Cuschieri J, Rizoli S, Rhind S, Junger WG
• Pre-hospital intubation factors and pneumonia in trauma patients.
  Surgical infections 2011 Evans HL, Warner K, Bulger EM, Sharar SR, Maier RV, Cuschieri J
• Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study.
  PLoS medicine 2011 Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD, Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program
• The Glue Grant experience: characterizing the post injury genomic response.
  European journal of trauma and emergency surgery : official publication of the European Trauma Society 2011 Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG, Inflammation and Host Response to Injury, Large Scale Collaborative Research Program
• Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury.
  The Journal of trauma 2011 Brakenridge SC, Phelan HA, Henley SS, Golden RM, Kashner TM, Eastman AE, Sperry JL, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators
• Clinical outcomes of linezolid vs vancomycin in methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia: retrospective analysis.
  Journal of intensive care medicine 2011 Chan JD, Pham TN, Wong J, Hessel M, Cuschieri J, Neff M, Dellit TH
• Steroids after severe injury: many unanswered questions.
  JAMA 2011 Bulger EM, Cuschieri J
• Human transcriptome array for high-throughput clinical studies.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W, Inflammation and Host …
• Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.
  The Journal of trauma 2011 Edmonds RD, Cuschieri J, Minei JP, Rosengart MR, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Sperry JL, Inflammation the Host Response to Injury Investigators
• Sew it up! A Western Trauma Association multi-institutional study of enteric injury management in the postinjury open abdomen.
  The Journal of trauma 2011 Burlew CC, Moore EE, Cuschieri J, Jurkovich GJ, Codner P, Crowell K, Nirula R, Haan J, Rowell SE, Kato CM, MacNew H, Ochsner MG, Harrison PB, Fusco C, Sauaia A, Kaups KL, WTA Study Group
• The association between the transfusion of older blood and outcomes after trauma.
  Shock (Augusta, Ga.) 2011 Hassan M, Pham TN, Cuschieri J, Warner KJ, Nester T, Maier RV, Shalhub S, O'Keefe GE
• Identification and interpretation of longitudinal gene expression changes in trauma.
  PloS one 2010 Rajicic N, Cuschieri J, Finkelstein DM, Miller-Graziano CL, Hayden D, Moldawer LL, Moore E, O'Keefe G, Pelik K, Warren HS, Schoenfeld DA, Inflammation and the Host Response to Injury Large Scale …
• Timing of intubation and ventilator-associated pneumonia following injury.
  Archives of surgery (Chicago, Ill. : 1960) 2010 Evans HL, Zonies DH, Warner KJ, Bulger EM, Sharar SR, Maier RV, Cuschieri J
• Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure.
  Shock (Augusta, Ga.) 2010 Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV, Inflammation and the Host Response to Injury Collaborative …
• Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.
  Journal of proteome research 2010 Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Inflammation and the Host …
• Clinical microfluidics for neutrophil genomics and proteomics.
  Nature medicine 2010 Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, …
• Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline.
  The Journal of surgical research 2010 Schaeffer V, Arbabi S, Garcia IA, Knoll ML, Cuschieri J, Bulger EM, Maier RV
• Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
  Proceedings of the National Academy of Sciences of the United States of America 2010 Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Inflammation and Host Response to Injury Program, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan…
• Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients.
  Archives of surgery (Chicago, Ill. : 1960) 2010 Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J
• Traditional resuscitative practices fail to resolve metabolic acidosis in morbidly obese patients after severe blunt trauma.
  The Journal of trauma 2010 Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J
• Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response.
  Critical care medicine 2010 Winfield RD, Delano MJ, Dixon DJ, Schierding WS, Cendan JC, Lottenberg L, Lopez MC, Baker HV, Cobb JP, Moldawer LL, Maier RV, Cuschieri J
• Oxidant alterations in CD16 expression are cytoskeletal induced.
  Shock (Augusta, Ga.) 2009 Cuschieri J, Sakr S, Bulger E, Knoll M, Arbabi S, Maier RV
• Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury.
  Annals of surgery 2009 Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV
• Analysis of the relationship between longitudinal gene expressions and ordered categorical event data.
  Statistics in medicine 2009 Rajicic N, Finkelstein DM, Schoenfeld DA, Inflammation and Host Response to Injury Research Program Investigators
• Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.
  The Journal of trauma 2009 Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB, Inflammation and Host Response to Injury Investigators
• Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients.
  The Journal of trauma 2009 Evans HL, Cuschieri J, Moore EE, Shapiro MB, Nathens AB, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, West MA, Inflammation and Host Response to Injury Investigators
• Single-dose etomidate for rapid sequence intubation may impact outcome after severe injury.
  The Journal of trauma 2009 Warner KJ, Cuschieri J, Jurkovich GJ, Bulger EM
• Assessing statistical significance in microarray experiments using the distance between microarrays.
  PloS one 2009 Hayden D, Lazar P, Schoenfeld D, Inflammation and the Host Response to Injury Investigators
• A genomic score prognostic of outcome in trauma patients.
  Molecular medicine (Cambridge, Mass.) 2009 Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, …
• Characterization of persistent hyperglycemia: what does it mean postinjury?
  The Journal of trauma 2009 Sperry JL, Frankel HL, Nathens AB, O'keefe GE, Cuschieri J, Moore EE, Maier RV, Minei JP, Inflammation and the Host Response to Injury Investigators
• Assessment of functional limitation after necrotizing soft tissue infection.
  Journal of burn care & research : official publication of the American Burn Association 2009 Pham TN, Moore ML, Costa BA, Cuschieri J, Klein MB
• The utility of early end-tidal capnography in monitoring ventilation status after severe injury.
  The Journal of trauma 2009 Warner KJ, Cuschieri J, Garland B, Carlbom D, Baker D, Copass MK, Jurkovich GJ, Bulger EM
• The evolution of the diagnostic work-up for stab wounds to the back and flank.
  Injury 2008 Pham TN, Heinberg E, Cuschieri J, Bulger EM, O'Keefe GE, Gross JA, Jurkovich GJ
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients.
  The Journal of trauma 2008 West MA, Moore EE, Shapiro MB, Nathens AB, Cuschieri J, Johnson JL, Harbrecht BG, Minei JP, Bankey PE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VIII--Nutritional support of the trauma patient.
  The Journal of trauma 2008 O'Keefe GE, Shelton M, Cuschieri J, Moore EE, Lowry SF, Harbrecht BG, Maier RV, Inflammation and the Host Response to Injury Collaborative Research Program
• Necrotizing soft tissue infection.
  Surgical infections 2008 Cuschieri J
• An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion.
  The Journal of trauma 2008 Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP, Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE, Inflammation the Host Response to Injury Investigators
• Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient.
  The Journal of trauma 2008 Cuschieri J, Freeman B, O'Keefe G, Harbrecht BG, Bankey P, Johnson JL, Minei JP, Sperry J, West M, Nathens A, Moore EE, Maier RV, Inflammation and the Host Response to Injury Collaborative Research …
• Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program.
  Annals of surgery 2008 SCOAP Collaborative, Cuschieri J, Florence M, Flum DR, Jurkovich GJ, Lin P, Steele SR, Symons RG, Thirlby R
• Survey of surgical infections currently known (SOSICK): a multicenter examination of antimicrobial use from the surgical infection society scientific studies committee.
  Surgical infections 2008 Namias N, Meizoso JP, Livingston DH, SOSICK Investigators Group
• Effect of immediate enteral feeding on trauma patients with an open abdomen: protection from nosocomial infections.
  Journal of the American College of Surgeons 2008 Dissanaike S, Pham T, Shalhub S, Warner K, Hennessy L, Moore EE, Maier RV, O'Keefe GE, Cuschieri J
• Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.
  Journal of the American College of Surgeons 2008 Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE
• Male gender is associated with excessive IL-6 expression following severe injury.
  The Journal of trauma 2008 Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, Remick DG, Minei JP, Inflammation and the Host Response to Injury Investigators
• Emergency department ventilation effects outcome in severe traumatic brain injury.
  The Journal of trauma 2008 Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM
• Insulin regulates macrophage activation through activin A.
  Shock (Augusta, Ga.) 2008 Cuschieri J, Bulger E, Grinsell R, Garcia I, Maier RV
• Mechanistic analysis of macrophage response to IRAK-1 gene knockdown by a smart polymer-antisense oligonucleotide therapeutic.
  Journal of biomaterials science. Polymer edition 2008 Johns RE, El-Sayed ME, Bulmus V, Cuschieri J, Maier R, Hoffman AS, Stayton PS
• Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient.
  The Journal of trauma 2007 Harbrecht BG, Minei JP, Shapiro MB, Nathens AB, Moore EE, West MA, Bankey PE, Cuschieri J, Johnson JL, Maier RV, Inflammation and the Host Response to Injury Scale Collaborative Research Project
• Oxidative stress, lipid rafts, and macrophage reprogramming.
  Antioxidants & redox signaling 2007 Cuschieri J, Maier RV
• The impact of prehospital ventilation on outcome after severe traumatic brain injury.
  The Journal of trauma 2007 Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM
• The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway.
  Shock (Augusta, Ga.) 2007 Schaeffer V, Cuschieri J, Garcia I, Knoll M, Billgren J, Jelacic S, Bulger E, Maier R
• Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock.
  Annals of surgery 2007 Bulger EM, Cuschieri J, Warner K, Maier RV
• The practice of venous thromboembolism prophylaxis in the major trauma patient.
  The Journal of trauma 2007 Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV
• Acid sphingomyelinase is required for lipid Raft TLR4 complex formation.
  Surgical infections 2007 Cuschieri J, Bulger E, Billgrin J, Garcia I, Maier RV
• Vitamin E inhibits endotoxin-mediated transport of phosphatases to lipid rafts.
  Shock (Augusta, Ga.) 2007 Cuschieri J, Bulger E, Biligren J, Garcia I, Maier RV
• Surgical management of acute necrotizing lung infections.
  Canadian respiratory journal 2006 Reimel BA, Krishnadasen B, Cuschieri J, Klein MB, Gross J, Karmy-Jones R
• Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation.
  Journal of leukocyte biology 2006 Cuschieri J, Billigren J, Maier RV
• Phosphatidylcholine-specific phospholipase C (PC-PLC) is required for LPS-mediated macrophage activation through CD14.
  Journal of leukocyte biology 2006 Cuschieri J, Billgren J, Maier RV
• The modeling of the radiation and response green's function of a fluid-loaded cylindrical shell with an external compliant layer.
  The Journal of the Acoustical Society of America 2006 Cuschieri JM
• Mitogen-activated protein kinase (MAPK).
  Critical care medicine 2005 Cuschieri J, Maier RV
• Accidental self-inflicted nail gun injury to the heart
  Injury Extra 2005 Pritts TA Knight D Davis BR Promebka D Cuschieri J
• Oxidative-induced calcium mobilization is dependent on annexin VI release from lipid rafts.
  Surgery 2005 Cuschieri J, Bulger E, Garcia I, Maier RV
• Central venous-arterial carbon dioxide difference as an indicator of cardiac index.
  Intensive care medicine 2005 Cuschieri J, Rivers EP, Donnino MW, Katilius M, Jacobsen G, Nguyen HB, Pamukov N, Horst HM
• Calcium/calmodulin-dependent kinase II is required for platelet-activating factor priming.
  Shock (Augusta, Ga.) 2005 Cuschieri J, Bulger E, Garcia I, Jelacic S, Maier RV
• The role of repeat angiography in the management of pelvic fractures.
  The Journal of trauma 2005 Shapiro M, McDonald AA, Knight D, Johannigman JA, Cuschieri J
• PKC-zeta is essential for endotoxin-induced macrophage activation.
  The Journal of surgical research 2004 Cuschieri J, Umanskiy K, Solomkin J
• Implications of lipid raft disintegration: enhanced anti-inflammatory macrophage phenotype.
  Surgery 2004 Cuschieri J
• Implications of proteasome inhibition: an enhanced macrophage phenotype.
  Cellular immunology 2004 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation.
  Shock (Augusta, Ga.) 2004 Cuschieri J, Bulmus V, Gourlay D, Garcia I, Hoffman A, Stayton P, Maier RV
• Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase.
  Shock (Augusta, Ga.) 2003 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation.
  Surgery 2003 Umanskiy K, Robinson C, Cave C, Williams MA, Lentsch AB, Cuschieri J, Solomkin JS
• Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo.
  Shock (Augusta, Ga.) 2003 Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV
• Endotoxin-induced endothelial cell proinflammatory phenotypic differentiation requires stress fiber polymerization.
  Shock (Augusta, Ga.) 2003 Cuschleri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• Modulation of endotoxin-induced endothelial activity by microtubule depolymerization.
  The Journal of trauma 2003 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• Stress-Induced Endothelial Cell Proinflammatory Phenotypic Differentiation Requires Stress Fiber Polymerization
  Shock. 2003:19(5):433-439. 2003 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV.
• Accidental self-inflicted nail gun injury to the heart
  Injury Extra 2002 Pritts TA, Knight D, Davis BR, Promebka D, Cuschieri J
• Platelet-activating factor priming of inflammatory cell activity requires cellular adherence.
  Surgery 2002 Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV
• Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness.
  The Journal of trauma 2002 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin.
  Journal of immunology (Baltimore, Md. : 1950) 2002 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV
• Role of bronchoscopy in massive hemoptysis.
  Chest surgery clinics of North America 2001 Karmy-Jones R, Cuschieri J, Vallières E
• Endotoxin Tolerance in Endothelial Cells is Reversed by Phosphatase Inhibition
  Surgical Forum, Vol LII 2001 Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV.
• Clearing the cervical spine in victims of blunt assault to the head and neck: what is necessary?
  The American surgeon 2000 Patton JH, Kralovich KA, Cuschieri J, Gasparri M
• Anterior mediastinal abscess after closed sternal fracture.
  The Journal of trauma 1999 Cuschieri J, Kralovich KA, Patton JH, Horst HM, Obeid FN, Karmy-Jones R