Joseph Caruso, PhD
Assistant Researcher
Pathology
School of Medicine
Publications (12)
Top publication keywords:
AlcoholsCyclin ECystadenomaIndolesRetinoblastoma ProteinCarcinoma, Intraductal, NoninfiltratingBreast NeoplasmsMetabolic Networks and PathwaysSelf ConceptCarcinoma, Ductal, BreastElafinCarcinogenesisEstrogen Receptor alphaOncogene ProteinsLeukocyte Elastase
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Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis.
Molecular cancer therapeutics 2024 Lulla AR, Akli S, Karakas C, Caruso JA, Warma LD, Fowlkes NW, Rao X, Wang J, Hunt KK, Watowich SS, Keyomarsi K -
Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.
Proceedings of the National Academy of Sciences of the United States of America 2023 Caruso JA, Wang X, Murrow LM, Rodriguez CI, Chen-Tanyolac C, Vu L, Chen YY, Gascard P, Gartner ZJ, Kerlikowske K, Tlsty TD -
Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition.
Gastroenterology 2023 Lee SH, Contreras Panta EW, Gibbs D, Won Y, Min J, Zhang C, Roland JT, Hong SH, Sohn Y, Krystofiak E, Jang B, Ferri L, Sangwan V, Ragoussis J, Camilleri-Broët S, Caruso J, Chen-Tanyolac C, Strasser M,… -
Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution.
Cell systems 2022 Murrow LM, Weber RJ, Caruso JA, McGinnis CS, Phong K, Gascard P, Rabadam G, Borowsky AD, Desai TA, Thomson M, Tlsty T, Gartner ZJ -
Remaining true to one's identity.
Nature aging 2021 Caruso JA, Tlsty TD
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Cytoplasmic Cyclin E Is an Independent Marker of Aggressive Tumor Biology and Breast Cancer-Specific Mortality in Women over 70 Years of Age.
Cancers 2020 Johnston SJ, Syed BM, Parks RM, Monteiro CJ, Caruso JA, Green AR, Ellis IO, Hunt KK, Karakas C, Keyomarsi K, Cheung KL -
Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies.
Cancer research 2018 Caruso JA, Duong MT, Carey JPW, Hunt KK, Keyomarsi K -
The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.
Oncogene 2014 Caruso JA, Akli S, Pageon L, Hunt KK, Keyomarsi K -
Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.
Breast cancer research : BCR 2014 Caruso JA, Karakas C, Zhang J, Yi M, Albarracin C, Sahin A, Bondy M, Liu J, Hunt KK, Keyomarsi K -
Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.
Cell cycle (Georgetown, Tex.) 2014 Caruso JA, Campana R, Wei C, Su CH, Hanks AM, Bornmann WG, Keyomarsi K -
The neutrophil elastase inhibitor elafin triggers rb-mediated growth arrest and caspase-dependent apoptosis in breast cancer.
Cancer research 2010 Caruso JA, Hunt KK, Keyomarsi K -
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Reproductive biology and endocrinology : RB&E 2009 Russo LA, Peano BJ, Trivedi SP, Cavalcanto TD, Olenchock BA, Caruso JA, Smolock AR, Vishnevsky O, Gardner RM