John Kornak, PhD
Professor
Epidemiology & Biostatistics
School of Medicine

Dr. Kornak received his BSc in Mathematics with Statistics (1996) and Ph.D. in Statistics (2000) from the University of Nottingham, UK. He spent time as a postdoc at UCSF and The Ohio State University before joining the Department of Radiology and Biomedical Imaging at UCSF in 2003. He transferred to Epidemiology and Biostatistics in July 2010 and is currently the Head of the Data Science Program and the Director of the CTSI Biostatistical Consulting Unit.

Awards

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• Excellence Award, UCSF CTSI Consultant of the Year Award, 2011
• Impact Award, UCSF CTSI Consultant of the Year Award, 2010
• Consistent Excellence Award, UCSF CTSI Consultant of the Year Award, 2009
• Elected Fellow, Royal Statistical Society, 1999

Education & Training

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• PhD Statistics University of Nottingham, UK 2000
• B.Sc. Mathematics University of Nottingham, UK 1996
• Postdoctoral Studies Graduate Division University of California, San Francisco

Interests

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• spatial statistics
• statistical image analysis
• Bayesian image analysis in Fourier Space
• Bayesian reconstruction of magnetic resonance imaging
• Bayesian statistics

Grants and Projects

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• Bayesian image analysis in Fourier space, NIH, 2017-2021

Publications (135)

Top publication keywords:
C9orf72 Proteintau ProteinsAtrophyPick Disease of the BrainBrainImage EnhancementBayes TheoremMagnetic Resonance AngiographyNeuropsychological TestsBreast NeoplasmsMagnetic Resonance ImagingFrontotemporal Lobar DegenerationNeoadjuvant TherapyImage Interpretation, Computer-AssistedFrontotemporal Dementia

• Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
  JAMA network open 2024 Staffaroni AM, Clark AL, Taylor JC, Heuer HW, Sanderson-Cimino M, Wise AB, Dhanam S, Cobigo Y, Wolf A, Manoochehri M, Forsberg L, Mester C, Rankin KP, Appleby BS, Bayram E, Bozoki A, Clark D, Darby RR…
• Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
  Research square 2024 Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, Li J, Loureiro J, Sivasankaran R, …
• 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.
  Radiology. Imaging cancer 2024 Diwanji D, Onishi N, Hathi DK, Lawhn-Heath C, Kornak J, Li W, Guo R, Molina-Vega J, Seo Y, Flavell RR, Heditsian D, Brain S, Esserman LJ, Joe BN, Hylton NM, Jones EF, Ray KM
• Factors associated with anxiety during the first two years of the COVID-19 pandemic in the United States: An analysis of the COVID-19 Citizen Science study.
  PloS one 2024 Cozen AE, Carton T, Hamad R, Kornak J, Faulkner Modrow M, Peyser ND, Park S, Orozco JH, Brandner M, O'Brien EC, Djibo DA, McMahill-Walraven CN, Isasi CR, Beatty AL, Olgin JE, Marcus GM, Pletcher MJ
• Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment.
  Radiology. Imaging cancer 2023 Onishi N, Bareng TJ, Gibbs J, Li W, Price ER, Joe BN, Kornak J, Esserman LJ, Newitt DC, Hylton NM, I-SPY 2 Imaging Working Group, I-SPY 2 Investigator Network

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• Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study.
  Radiology 2023 Arasu VA, Habel LA, Achacoso NS, Buist DSM, Cord JB, Esserman LJ, Hylton NM, Glymour MM, Kornak J, Kushi LH, Lewis DA, Liu VX, Lydon CM, Miglioretti DL, Navarro DA, Pu A, Shen L, Sieh W, Yoon HC, Lee …
• A complex systems model of breast cancer etiology: The Paradigm II Model.
  PloS one 2023 Hiatt RA, Worden L, Rehkopf D, Engmann N, Troester M, Witte JS, Balke K, Jackson C, Barlow J, Fenton SE, Gehlert S, Hammond RA, Kaplan G, Kornak J, Nishioka K, McKone T, Smith MT, Trasande L, Porco TC
• Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2023 Taylor JC, Heuer HW, Clark AL, Wise AB, Manoochehri M, Forsberg L, Mester C, Rao M, Brushaber D, Kramer J, Welch AE, Kornak J, Kremers W, Appleby B, Dickerson BC, Domoto-Reilly K, Fields JA, Ghoshal N…
• Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.
  Journal of neurology, neurosurgery, and psychiatry 2023 Asken BM, Ljubenkov PA, Staffaroni AM, Casaletto KB, Vandevrede L, Cobigo Y, Rojas-Rodriguez JC, Rankin KP, Kornak J, Heuer H, Shigenaga J, Appleby BS, Bozoki AC, Domoto-Reilly K, Ghoshal N, Huey E, …
• Factors Associated With Long COVID Symptoms in an Online Cohort Study.
  Open forum infectious diseases 2023 Durstenfeld MS, Peluso MJ, Peyser ND, Lin F, Knight SJ, Djibo A, Khatib R, Kitzman H, O'Brien E, Williams N, Isasi C, Kornak J, Carton TW, Olgin JE, Pletcher MJ, Marcus GM, Beatty AL
• Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Kremers W, Lapid MI, Leger G, …
• Factors Associated with Long Covid Symptoms in an Online Cohort Study.
  medRxiv : the preprint server for health sciences 2022 Durstenfeld MS, Peluso MJ, Peyser ND, Lin F, Knight SJ, Djibo A, Khatib R, Kitzman H, O'Brien E, Williams N, Isasi C, Kornak J, Carton TW, Olgin JE, Pletcher MJ, Marcus GM, Beatty AL
• Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
  Nature medicine 2022 Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, …
• Diffusion-Weighted MRI for Predicting Pathologic Complete Response in Neoadjuvant Immunotherapy.
  Cancers 2022 Li W, Le NN, Onishi N, Newitt DC, Wilmes LJ, Gibbs JE, Carmona-Bozo J, Liang J, Partridge SC, Price ER, Joe BN, Kornak J, Magbanua MJM, Nanda R, LeStage B, Esserman LJ, Van't Veer LJ, Hylton NM
• Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling.
  NeuroImage. Clinical 2022 Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, Perrin RJ, Kramer J, Rosen HJ, Alzheimer’s …
• Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia.
  Neurology 2022 Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mackenzie IR…
• Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection.
  JCI insight 2022 Durstenfeld MS, Peluso MJ, Kelly JD, Win S, Swaminathan S, Li D, Arechiga VM, Zepeda V, Sun K, Shao S, Hill C, Arreguin MI, Lu S, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kornak J, …
• Proposed research criteria for prodromal behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2022 Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, …
• Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer.
  Tomography (Ann Arbor, Mich.) 2022 Le NN, Li W, Onishi N, Newitt DC, Gibbs JE, Wilmes LJ, Kornak J, Partridge SC, LeStage B, Price ER, Joe BN, Esserman LJ, Hylton NM
• Post-Processing Bias Field Inhomogeneity Correction for Assessing Background Parenchymal Enhancement on Breast MRI as a Quantitative Marker of Treatment Response.
  Tomography (Ann Arbor, Mich.) 2022 Nguyen AA, Onishi N, Carmona-Bozo J, Li W, Kornak J, Newitt DC, Hylton NM
• The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Silverman HE, Ake JM, Manoochehri M, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Fields JA, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Lapid MI, Litvan I, …
• Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response.
  Radiology 2021 Onishi N, Li W, Newitt DC, Harnish RJ, Strand F, Nguyen AA, Arasu VA, Gibbs J, Jones EF, Wilmes LJ, Kornak J, Joe BN, Price ER, Ojeda-Fournier H, Eghtedari M, Zamora KW, Woodard S, Umphrey HR, Nelson …
• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
  Neurology 2021 Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, …
• Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2021 Barker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung …
• Association of a Proposed New Staging System for Folliculotropic Mycosis Fungoides With Prognostic Variables in a US Cohort.
  JAMA dermatology 2021 Charli-Joseph Y, Kashani-Sabet M, McCalmont TH, Kornak J, Allen I, Ai WZ, LeBoit PE, Pincus LB
• Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.
  Scientific reports 2020 Hathi DK, Li W, Seo Y, Flavell RR, Kornak J, Franc BL, Joe BN, Esserman LJ, Hylton NM, Jones EF
• Brain volumetric deficits in MAPT mutation carriers: a multisite study.
  Annals of clinical and translational neurology 2020 Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, …
• Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL.
  NPJ breast cancer 2020 Li W, Newitt DC, Gibbs J, Wilmes LJ, Jones EF, Arasu VA, Strand F, Onishi N, Nguyen AA, Kornak J, Joe BN, Price ER, Ojeda-Fournier H, Eghtedari M, Zamora KW, Woodard SA, Umphrey H, Bernreuter W, …
• Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH
• Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.
  JAMA network open 2020 Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, …
• Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.
  Journal of breast imaging 2020 Arasu VA, Kim P, Li W, Strand F, McHargue C, Harnish R, Newitt DC, Jones EF, Glymour MM, Kornak J, Esserman LJ, Hylton NM, ISPY2 investigators
• Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Gentry MT, Lapid MI, Syrjanen J, Calvert K, Hughes S, Brushaber D, Kremers W, Bove J, Brannelly P, Coppola G, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, …
• Longitudinal structural and metabolic changes in frontotemporal dementia.
  Neurology 2020 Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, Rabinovici GD
• Impact of MRI Protocol Adherence on Prediction of Pathological Complete Response in the I-SPY 2 Neoadjuvant Breast Cancer Trial.
  Tomography (Ann Arbor, Mich.) 2020 Onishi N, Li W, Gibbs J, Wilmes LJ, Nguyen A, Jones EF, Arasu V, Kornak J, Joe BN, Esserman LJ, Newitt DC, Hylton NM
• Tumor Sphericity Predicts Response in Neoadjuvant Chemotherapy for Invasive Breast Cancer.
  Tomography (Ann Arbor, Mich.) 2020 Li W, Newitt DC, Yun B, Jones EF, Arasu V, Wilmes LJ, Gibbs J, Nguyen AA, Onishi N, Kornak J, Joe BN, Esserman LJ, Hylton NM
• Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials.
  Neurology 2020 Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer H, Hsiung …
• Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, …
• Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, …
• The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Boeve B, Bove J, Brannelly P, Brushaber D, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-…
• Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen H, Boeve B, ARTFL/LEFFTDS Consortium
• Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung …
• Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel…
• Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber DE, Caso C, Coppola G, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, …
• Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, Dickinson S, Domoto-…
• Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen HJ, Boeve BF, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever …
• Nonlinear Z-score modeling for improved detection of cognitive abnormality.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, …
• Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial.
  JAMA internal medicine 2019 Possin KL, Merrilees JJ, Dulaney S, Bonasera SJ, Chiong W, Lee K, Hooper SM, Allen IE, Braley T, Bernstein A, Rosa TD, Harrison K, Begert-Hellings H, Kornak J, Kahn JG, Naasan G, Lanata S, Clark AM, …
• Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy.
  Neuron 2019 Brown JA, Deng J, Neuhaus J, Sible IJ, Sias AC, Lee SE, Kornak J, Marx GA, Karydas AM, Spina S, Grinberg LT, Coppola G, Geschwind DH, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW
• Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers.
  Neurobiology of aging 2019 Chen Q, Boeve BF, Schwarz CG, Reid R, Tosakulwong N, Lesnick TG, Bove J, Brannelly P, Brushaber D, Coppola G, Dheel C, Dickerson BC, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, …
• Neuropathological correlates of structural and functional imaging biomarkers in 4-repeat tauopathies.
  Brain : a journal of neurology 2019 Spina S, Brown JA, Deng J, Gardner RC, Nana AL, Hwang JL, Gaus SE, Huang EJ, Kramer JH, Rosen HJ, Kornak J, Neuhaus J, Miller BL, Grinberg LT, Boxer AL, Seeley WW
• The costs of dementia subtypes to California Medicare fee-for-service, 2015.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2019 Chen Y, Wilson L, Kornak J, Dudley RA, Merrilees J, Bonasera SJ, Byrne CM, Lee K, Chiong W, Miller BL, Possin KL
• Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.
  Journal of magnetic resonance imaging : JMRI 2019 Li W, Newitt DC, Wilmes LJ, Jones EF, Arasu V, Gibbs J, La Yun B, Li E, Partridge SC, Kornak J, I-SPY 2 Consortium, Esserman LJ, Hylton NM
• Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.
  Brain : a journal of neurology 2019 Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller…
• Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.
  Annals of clinical and translational neurology 2018 Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, …
• Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.
  NPJ breast cancer 2018 Huang SY, Franc BL, Harnish RJ, Liu G, Mitra D, Copeland TP, Arasu VA, Kornak J, Jones EF, Behr SC, Hylton NM, Price ER, Esserman L, Seo Y
• Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease.
  Annals of neurology 2018 Azevedo CJ, Cen SY, Khadka S, Liu S, Kornak J, Shi Y, Zheng L, Hauser SL, Pelletier D
• The Rural Inpatient Mortality Study: Does Urban-Rural County Classification Predict Hospital Mortality in California?
  The Permanente journal 2018 Linnen DT, Kornak J, Stephens C
• Clinicopathological correlations in behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2017 Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel…
• Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard.
  NMR in biomedicine 2017 Starobinets O, Simko JP, Kuchinsky K, Kornak J, Carroll PR, Greene KL, Kurhanewicz J, Noworolski SM
• Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
  NeuroImage. Clinical 2017 Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ
• Associations of Body Mass Index and Body Fat With Markers of Inflammation and Nutrition Among Patients Receiving Hemodialysis.
  American journal of kidney diseases : the official journal of the National Kidney Foundation 2017 Delgado C, Chertow GM, Kaysen GA, Dalrymple LS, Kornak J, Grimes B, Johansen KL
• Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
  Brain and behavior 2017 Binney RJ, Pankov A, Marx G, He X, McKenna F, Staffaroni AM, Kornak J, Attygalle S, Boxer AL, Schuff N, Gorno-Tempini ML, Weiner MW, Kramer JH, Miller BL, Rosen HJ
• Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.
  Tomography (Ann Arbor, Mich.) 2016 Li W, Arasu V, Newitt DC, Jones EF, Wilmes L, Gibbs J, Kornak J, Joe BN, Esserman LJ, Hylton NM, ACRIN 6657 Trial Team and I-SPY Investigators Network
• Out-of-Network Emergency Department Use among Managed Medicaid Beneficiaries.
  Health services research 2016 Raven MC, Guzman D, Chen AH, Kornak J, Kushel M
• Progression of brain atrophy in PSP and CBS over 6 months and 1 year.
  Neurology 2016 Dutt S, Binney RJ, Heuer HW, Luong P, Attygalle S, Bhatt P, Marx GA, Elofson J, Tartaglia MC, Litvan I, McGinnis SM, Dickerson BC, Kornak J, Waltzman D, Voltarelli L, Schuff N, Rabinovici GD, Kramer …
• Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.
  Annals of clinical and translational neurology 2016 Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS
• Improving Screening Mammography Outcomes Through Comparison With Multiple Prior Mammograms.
  AJR. American journal of roentgenology 2016 Hayward JH, Ray KM, Wisner DJ, Kornak J, Lin W, Joe BN, Sickles EA
• Variability and bias assessment in breast ADC measurement across multiple systems.
  Journal of magnetic resonance imaging : JMRI 2016 Keenan KE, Peskin AP, Wilmes LJ, Aliu SO, Jones EF, Li W, Kornak J, Newitt DC, Hylton NM
• Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.
  PloS one 2016 Lo WC, Li W, Jones EF, Newitt DC, Kornak J, Wilmes LJ, Esserman LJ, Hylton NM
• US Findings in Patients at Risk for Pancreas Transplant Failure.
  Radiology 2016 Morgan TA, Smith-Bindman R, Harbell J, Kornak J, Stock PG, Feldstein VA
• Association of Self-Reported Frailty with Falls and Fractures among Patients New to Dialysis.
  American journal of nephrology 2015 Delgado C, Shieh S, Grimes B, Chertow GM, Dalrymple LS, Kaysen GA, Kornak J, Johansen KL
• Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration.
  NeuroImage. Clinical 2015 Pankov A, Binney RJ, Staffaroni AM, Kornak J, Attygalle S, Schuff N, Weiner MW, Kramer JH, Dickerson BC, Miller BL, Rosen HJ
• Internal mammary lymph nodes as incidental findings at screening breast MRI.
  Clinical imaging 2015 Ray KM, Munir R, Wisner DJ, Azziz A, Holland BC, Kornak J, Joe BN
• Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.
  Annals of clinical and translational neurology 2015 Insel PS, Mattsson N, Mackin RS, Kornak J, Nosheny R, Tosun-Turgut D, Donohue MC, Aisen PS, Weiner MW, Alzheimer's Disease Neuroimaging Initiative
• Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis.
  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2015 Kaysen GA, Johansen KL, Chertow GM, Dalrymple LS, Kornak J, Grimes B, Dwyer T, Chassy AW, Fiehn O
• Gradient nonlinearity correction to improve apparent diffusion coefficient accuracy and standardization in the american college of radiology imaging network 6698 breast cancer trial.
  Journal of magnetic resonance imaging : JMRI 2015 Newitt DC, Tan ET, Wilmes LJ, Chenevert TL, Kornak J, Marinelli L, Hylton N
• Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography.
  Alzheimer's research & therapy 2015 Sha SJ, Ghosh PM, Lee SE, Corbetta-Rastelli C, Jagust WJ, Kornak J, Rankin KP, Grinberg LT, Vinters HV, Mendez MF, Dickson DW, Seeley WW, Gorno-Tempini M, Kramer J, Miller BL, Boxer AL, Rabinovici GD
• Odanacatib treatment affects trabecular and cortical bone in the femur of postmenopausal women: results of a two-year placebo-controlled trial.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Engelke K, Fuerst T, Dardzinski B, Kornak J, Ather S, Genant HK, de Papp A
• The risk of melanoma in airline pilots and cabin crew: a meta-analysis.
  JAMA dermatology 2015 Sanlorenzo M, Wehner MR, Linos E, Kornak J, Kainz W, Posch C, Vujic I, Johnston K, Gho D, Monico G, McGrath JT, Osella-Abate S, Quaglino P, Cleaver JE, Ortiz-Urda S
• Vaginal shape at resting pelvic MRI: predictor of pelvic floor weakness?
  Clinical imaging 2014 Tillack AA, Joe BN, Yeh BM, Jun SL, Kornak J, Zhao S, Deng D
• Depression is not associated with peripheral insulin resistance in patients with chronic hepatitis C infection.
  Journal of viral hepatitis 2014 Shah SC, Kornak J, Khalili M
• In vivo evidence of glutamate toxicity in multiple sclerosis.
  Annals of neurology 2014 Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D
• Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.
  JAMA neurology 2014 Llufriu S, Kornak J, Ratiney H, Oh J, Brenneman D, Cree BA, Sampat M, Hauser SL, Nelson SJ, Pelletier D
• Comparison of self-report-based and physical performance-based frailty definitions among patients receiving maintenance hemodialysis.
  American journal of kidney diseases : the official journal of the National Kidney Foundation 2014 Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, Chertow GM
• Calibration of the brief food frequency questionnaire among patients on dialysis.
  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2014 Delgado C, Ward P, Chertow GM, Storer L, Dalrymple L, Block T, Kaysen GA, Kornak J, Grimes B, Kutner NG, Johansen KL
• Real-Time Measurement of Functional Tumor Volume by MRI to Assess Treatment Response in Breast Cancer Neoadjuvant Clinical Trials: Validation of the Aegis SER Software Platform.
  Translational oncology 2014 Newitt DC, Aliu SO, Witcomb N, Sela G, Kornak J, Esserman L, Hylton NM
• Repeatability of quantitative MRI measurements in normal breast tissue.
  Translational oncology 2014 Aliu SO, Jones EF, Azziz A, Kornak J, Wilmes LJ, Newitt DC, Suzuki SA, Klifa C, Gibbs J, Proctor EC, Joe BN, Hylton NM
• Application of quantitative DTI metrics in sporadic CJD.
  NeuroImage. Clinical 2014 Caverzasi E, Henry RG, Vitali P, Lobach IV, Kornak J, Bastianello S, Dearmond SJ, Miller BL, Rosen HJ, Mandelli ML, Geschwind MD
• Aggressive and minimally invasive surgery for pulmonary metastasis of sarcoma.
  The Journal of thoracic and cardiovascular surgery 2014 Reza J, Sammann A, Jin C, Horvai A, Hudnall M, Jablons DM, Jahan T, Kornak J, Mann MJ
• Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.
  Journal of magnetic resonance imaging : JMRI 2013 Jafri NF, Newitt DC, Kornak J, Esserman LJ, Joe BN, Hylton NM
• High-resolution diffusion-weighted imaging for the separation of benign from malignant BI-RADS 4/5 lesions found on breast MRI at 3T.
  Journal of magnetic resonance imaging : JMRI 2013 Wisner DJ, Rogers N, Deshpande VS, Newitt DN, Laub GA, Porter DA, Kornak J, Joe BN, Hylton NM
• Risk of thyroid cancer based on thyroid ultrasound imaging characteristics: results of a population-based study.
  JAMA internal medicine 2013 Smith-Bindman R, Lebda P, Feldstein VA, Sellami D, Goldstein RB, Brasic N, Jin C, Kornak J
• Association between body composition and frailty among prevalent hemodialysis patients: a US Renal Data System special study.
  Journal of the American Society of Nephrology : JASN 2013 Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, Chertow GM
• High resolution in vivo characterization of apparent diffusion coefficient at the tumor-stromal boundary of breast carcinomas: a pilot study to assess treatment response using proximity-dependent diffusion-weighted imaging.
  Journal of magnetic resonance imaging : JMRI 2013 McLaughlin RL, Newitt DC, Wilmes LJ, Jones EF, Wisner DJ, Kornak J, Proctor E, Joe BN, Hylton NM
• Depressive symptoms in Chinese-American subjects with cognitive impairment.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013 Chao SZ, Matthews BR, Yokoyama JS, Lai NB, Ong H, Tse M, Yuan RF, Lin A, Kramer J, Yaffe K, Kornak J, Miller BL, Rosen HJ
• Changes in serum inflammatory markers are associated with changes in apolipoprotein A1 but not B after the initiation of dialysis.
  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013 Kaysen GA, Dalrymple LS, Grimes B, Chertow GM, Kornak J, Johansen KL
• MRI enhancement in stromal tissue surrounding breast tumors: association with recurrence free survival following neoadjuvant chemotherapy.
  PloS one 2013 Jones EF, Sinha SP, Newitt DC, Klifa C, Kornak J, Park CC, Hylton NM
• High-resolution diffusion-weighted imaging for monitoring breast cancer treatment response.
  Academic radiology 2013 Wilmes LJ, McLaughlin RL, Newitt DC, Singer L, Sinha SP, Proctor E, Wisner DJ, Saritas EU, Kornak J, Shankaranarayanan A, Banerjee S, Jones EF, Joe BN, Hylton NM
• Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, …
• Age-related loss of proximal femoral strength in elderly men and women: the Age Gene/Environment Susceptibility Study--Reykjavik.
  Bone 2011 Lang TF, Sigurdsson S, Karlsdottir G, Oskarsdottir D, Sigmarsdottir A, Chengshi J, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Keyak JH
• Behaviour, physiology and experience of pathological laughing and crying in amyotrophic lateral sclerosis.
  Brain : a journal of neurology 2011 Olney NT, Goodkind MS, Lomen-Hoerth C, Whalen PK, Williamson CA, Holley DE, Verstaen A, Brown LM, Miller BL, Kornak J, Levenson RW, Rosen HJ
• Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD.
  Neurology 2011 Rabinovici GD, Rosen HJ, Alkalay A, Kornak J, Furst AJ, Agarwal N, Mormino EC, O'Neil JP, Janabi M, Karydas A, Growdon ME, Jang JY, Huang EJ, Dearmond SJ, Trojanowski JQ, Grinberg LT, Gorno-Tempini ML…
• The relationship between Gulf War illness, brain N-acetylaspartate, and post-traumatic stress disorder.
  Military medicine 2011 Weiner MW, Meyerhoff DJ, Neylan TC, Hlavin J, Ramage ER, McCoy D, Studholme C, Cardenas V, Marmar C, Truran D, Chu PW, Kornak J, Furlong CE, McCarthy C
• Spatially extended FMRI signal response to stimulus in non-functionally relevant regions of the human brain: preliminary results.
  The open neuroimaging journal 2011 Kornak J, Hall DA, Haggard MP
• Bayesian decision analysis for choosing between diagnostic/prognostic prediction procedures.
  Statistics and its interface 2011 Kornak J, Lu Y
• In vivo magnetic resonance imaging and optical imaging comparison of viable and nonviable mesenchymal stem cells with a bifunctional label.
  Molecular imaging 2010 Sutton EJ, Henning TD, Boddington S, Demos S, Krug C, Meier R, Kornak J, Zhao S, Baehner R, Sharifi S, Daldrup-Link H
• A statistical method (cross-validation) for bone loss region detection after spaceflight.
  Australasian physical & engineering sciences in medicine 2010 Zhao Q, Li W, Li C, Chu PW, Kornak J, Lang TF, Fang J, Lu Y
• In vivo 3.0-tesla magnetic resonance T1rho and T2 relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms.
  Magnetic resonance in medicine 2010 Blumenkrantz G, Zuo J, Li X, Kornak J, Link TM, Majumdar S
• The Alzheimer's Disease Neuroimaging Initiative: Annual change in biomarkers and clinical outcomes.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2010 Beckett LA, Harvey DJ, Gamst A, Donohue M, Kornak J, Zhang H, Kuo JH, Alzheimer's Disease Neuroimaging Initiative
• Comparing 3 T and 1.5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry.
  Human brain mapping 2010 Ho AJ, Hua X, Lee S, Leow AD, Yanovsky I, Gutman B, Dinov ID, Leporé N, Stein JL, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM, …
• Bayesian k -space-time reconstruction of MR spectroscopic imaging for enhanced resolution.
  IEEE transactions on medical imaging 2010 Kornak J, Young K, Soher BJ, Maudsley AA
• Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals.
  NeuroImage 2010 Hua X, Lee S, Hibar DP, Yanovsky I, Leow AD, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM, Alzheimer's Disease Neuroimaging Initiative
• ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia.
  Alzheimer disease and associated disorders 2010 Chao LL, Buckley ST, Kornak J, Schuff N, Madison C, Yaffe K, Miller BL, Kramer JH, Weiner MW
• Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using (1)H HR-MAS spectroscopy.
  Magma (New York, N.Y.) 2009 Cohn BR, Joe BN, Zhao S, Kornak J, Zhang VY, Iman R, Kurhanewicz J, Vahidi K, Yu J, Caughey AB, Swanson MG
• Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects.
  NeuroImage 2009 Hua X, Lee S, Yanovsky I, Leow AD, Chou YY, Ho AJ, Gutman B, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM, Alzheimer's Disease …
• Evidence for ongoing brain injury in human immunodeficiency virus-positive patients treated with antiretroviral therapy.
  Journal of neurovirology 2009 Cardenas VA, Meyerhoff DJ, Studholme C, Kornak J, Rothlind J, Lampiris H, Neuhaus J, Grant RM, Chao LL, Truran D, Weiner MW
• Bone fracture risk estimation based on image similarity.
  Bone 2009 Li W, Kornak J, Harris TB, Keyak J, Li C, Lu Y, Cheng X, Lang T
• Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition.
  NeuroImage 2009 Leow AD, Yanovsky I, Parikshak N, Hua X, Lee S, Toga AW, Jack CR, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Borowski B, Shaw LM, Trojanowski JQ, Fleisher AS, Harvey D, Kornak J, Schuff N, …
• K-Bayes reconstruction for perfusion MRI II: modeling and technical development.
  Journal of digital imaging 2009 Kornak J, Young K
• T2-Weighted endorectal magnetic resonance imaging of prostate cancer after external beam radiation therapy.
  International braz j urol : official journal of the Brazilian Society of Urology 2009 Westphalen AC, Kurhanewicz J, Cunha RM, Hsu IC, Kornak J, Zhao S, Coakley FV
• K-Bayes reconstruction for perfusion MRI. I: concepts and application.
  Journal of digital imaging 2009 Kornak J, Young K, Schuff N, Du A, Maudsley AA, Weiner MW
• Identify fracture-critical regions inside the proximal femur using statistical parametric mapping.
  Bone 2008 Li W, Kornak J, Harris T, Keyak J, Li C, Lu Y, Cheng X, Lang T
• Body mass index and magnetic resonance markers of brain integrity in adults.
  Annals of neurology 2008 Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ
• Diffusion tensor imaging of the pyramidal tracts in infants with motor dysfunction.
  Neurology 2008 Ludeman NA, Berman JI, Wu YW, Jeremy RJ, Kornak J, Bartha AI, Barkovich AJ, Ferriero DM, Henry RG, Glenn OA
• 3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry.
  NeuroImage 2008 Hua X, Leow AD, Lee S, Klunder AD, Toga AW, Lepore N, Chou YY, Brun C, Chiang MC, Barysheva M, Jack CR, Bernstein MA, Britson PJ, Ward CP, Whitwell JL, Borowski B, Fleisher AS, Fox NC, Boyes RG, …
• Abnormal N-acetylaspartate in hippocampus and anterior cingulate in posttraumatic stress disorder.
  Psychiatry research 2008 Schuff N, Neylan TC, Fox-Bosetti S, Lenoci M, Samuelson KW, Studholme C, Kornak J, Marmar CR, Weiner MW
• Voxel-based modeling and quantification of the proximal femur using inter-subject registration of quantitative CT images.
  Bone 2007 Li W, Kezele I, Collins DL, Zijdenbos A, Keyak J, Kornak J, Koyama A, Saeed I, Leblanc A, Harris T, Lu Y, Lang T
• Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging.
  Alzheimer disease and associated disorders 2006 Zhu X, Schuff N, Kornak J, Soher B, Yaffe K, Kramer JH, Ezekiel F, Miller BL, Jagust WJ, Weiner MW
• Longitudinal stability of MRI for mapping brain change using tensor-based morphometry.
  NeuroImage 2006 Leow AD, Klunder AD, Jack CR, Toga AW, Dale AM, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Whitwell JL, Borowski BJ, Fleisher AS, Fox NC, Harvey D, Kornak J, Schuff N, Studholme C, Alexander GE, …
• A non-parametric approach for co-analysis of multi-modal brain imaging data: application to Alzheimer's disease.
  NeuroImage 2006 Hayasaka S, Du AT, Duarte A, Kornak J, Jahng GH, Weiner MW, Schuff N
• Age effects on atrophy rates of entorhinal cortex and hippocampus.
  Neurobiology of aging 2005 Du AT, Schuff N, Chao LL, Kornak J, Jagust WJ, Kramer JH, Reed BR, Miller BL, Norman D, Chui HC, Weiner MW
• White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy.
  Neurobiology of aging 2005 Du AT, Schuff N, Chao LL, Kornak J, Ezekiel F, Jagust WJ, Kramer JH, Reed BR, Miller BL, Norman D, Chui HC, Weiner MW
• Summarizing complexity in high dimensions.
  Physical review letters 2005 Young K, Chen Y, Kornak J, Matson GB, Schuff N
• Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus.
  Alzheimer disease and associated disorders 2004 Ezekiel F, Chao L, Kornak J, Du AT, Cardenas V, Truran D, Jagust W, Chui H, Miller B, Yaffe K, Schuff N, Weiner M
• A method for determining venous contribution to BOLD contrast sensory activation.
  Magnetic resonance imaging 2002 Hall DA, Gonçalves MS, Smith S, Jezzard P, Haggard MP, Kornak J