John Featherstone, PhD
Professor Emeritus
Preventive & Restor Dent Sci
School of Dentistry
John D. Featherstone, MSc, PhD, is Professor Emeritus of Preventive and Restorative Dental Sciences at the University of California, San Francisco (UCSF) and the prior Dean of the School of Dentistry. He earned his M.Sc. in physical chemistry from the University of Manchester (UK) and a Ph.D. in chemistry from the University of Wellington (New Zealand).
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His research over the past 48 years has covered several aspects of cariology (study of tooth decay), he was one of the scientists who established how fluoride really works, and he was a pioneer in research on laser interactions with hard tissues. His work has led to the development and marketing of new lasers that have advanced laser dentistry. He spearheaded the development of CAMBRA® (caries management by risk assessment) at UCSF and is currently active in encouraging the implementation of Optimal Intervention Dentistry across the world.
He has received numerous National and International awards, including the Distinguished Scientist Award for Research in Dental Caries from the International Association for Dental Research (2002); the Zsolnai Prize for outstanding research in dental caries from the European Organization for Caries Research (2002); T.H. Maiman Award: for excellence in dental laser research. Academy of Laser Dentistry, 2002; the Norton Ross Award for excellence in clinical research from the American Dental Association (2007); the Lifetime Achievment Medal from the Alpha Omega International Dental Organization, 2022 and the Americn Dental Association Distinguished Service Award, 2023. He is as an Honorary Fellow of the American College of Dentists, the Pierre Fouchard Society, an honorary lifetime member of the Academy of Laser Dentistry and also an honorary lifetime member of the American Dental Association.
He has published over 320 papers and book chapters. He was principal investigator or co-investigator on numerous research grants and contracts over the past 40 years, largely from the National Institutes of Health.
Awards
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- Norton Ross Award, American Dental Association, 2007
- Zsolnai Prize, European Caries Research Organization, 2002
- Ericsson Prize in Preventive Dentistry, Swedish Patent Fund, 2002
- Distinguished Scientist Award, International Association for Dental Research, 2000
Education & Training
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- M.Sc. Physical Chemistry University of Manchester (UK)
- Ph.D. Chemistry University of Wellington (New Zealand)
Websites
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- Profile at cmb.ucsf.edu (cmb.ucsf.edu)
Grants and Projects
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- Laser Effects on Dental Hard Tissues, NIH, 1992-2009
- Caries Management by Risk Assessment, NIH, 1998-2004
- Cystatin Protease Interactions--the Effects of Surfaces, NIH, 1993-1998
- Scientific Review and Evaluation Award-nidr Special Gran, NIH, 1985-1995
- Clinical Aspects of De/remineralization of Teeth, NIH, 1993-1995
- Small Instrumentation Grant, NIH, 1991-1992
- Purchase of Quantitative Microradiography Equipment, NIH, 1989-1990
- Precision Hard Tissue Sectioning Machine, NIH, 1987-1988
- Scanning Electron Microscope Purchase, NIH, 1987-1988
- Fluoride Effect on Human Tooth Root Caries, NIH, 1984-1987
- Effects of Barium on Human Enamel and Dental Caries, NIH, 1984-1986
Publications (95)
Top publication keywords:
Streptococcus mutansCariostatic AgentsTooth DemineralizationDental CariesLasers, GasDental CareDental EnamelDental Restoration, PermanentDental PlaqueDental Caries SusceptibilityToothpastesDentistsFluorides, TopicalTooth RemineralizationFluorides
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Recommendations on Topical Fluoride Usage for Caries Management in East Asia.
International dental journal 2024 Zheng FM, Adiatman M, Chu CH, Crystal YO, Featherstone JD, Hoang TH, Kim BI, Ogawa H, Pitiphat W, Kadir RA, Wong ML, Zheng S -
Dental restorative materials containing quaternary ammonium compounds have sustained antibacterial action.
Journal of the American Dental Association (1939) 2022 Featherstone JDB -
A Comparison of Four Caries Risk Assessment Methods.
Frontiers in oral health 2021 Featherstone JDB, Crystal YO, Alston P, Chaffee BW, Doméjean S, Rechmann P, Zhan L, Ramos-Gomez F -
Evidence-Based Caries Management for All Ages-Practical Guidelines.
Frontiers in oral health 2021 Featherstone JDB, Crystal YO, Alston P, Chaffee BW, Doméjean S, Rechmann P, Zhan L, Ramos-Gomez F -
The Adaptive Morphology of Bacillus subtilis Biofilms: A Defense Mechanism against Bacterial Starvation.
Microorganisms 2019 Gingichashvili S, Duanis-Assaf D, Shemesh M, Featherstone JDB, Feuerstein O, Steinberg D
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Exposure of Streptococcus mutans and Streptococcus sanguinis to blue light in an oral biofilm model.
Lasers in medical science 2019 Vaknin M, Steinberg D, Featherstone JD, Feuerstein O -
Efficacy of an adenosine triphosphate meter for evaluating caries risk in clinical dental practice.
Journal of the American Dental Association (1939) 2019 Rechmann P, Chaffee BW, Rechmann BMT, Featherstone JDB -
Caries Management by Risk Assessment: Results from a Practice-Based Research Network Study.
Journal of the California Dental Association 2019 Rechmann P, Chaffee BW, Rechmann BMT, Featherstone JDB -
Integrating Caries Management by Risk Assessment (CAMBRA) and Prevention Strategies Into the Contemporary Dental Practice.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2018 Rechmann P, Kinsel R, Featherstone JDB -
Change of salivary fluoride level with intake of fluoride releasing lozenges: A pilot study.
Journal of investigative and clinical dentistry 2018 Rechmann P, Rechmann BMT, Kinsel R, Featherstone JDB -
Calibration of dentists for Caries Management by Risk Assessment Research in a Practice Based Research Network - CAMBRA PBRN.
BMC oral health 2018 Rechmann P, Jue B, Santo W, Rechmann BMT, Featherstone JDB -
MI Varnish and MI Paste Plus in a caries prevention and remineralization study: a randomized controlled trial.
Clinical oral investigations 2018 Rechmann P, Bekmezian S, Rechmann BMT, Chaffee BW, Featherstone JDB -
Bacillus subtilis Biofilm Development - A Computerized Study of Morphology and Kinetics.
Frontiers in microbiology 2017 Gingichashvili S, Duanis-Assaf D, Shemesh M, Featherstone JDB, Feuerstein O, Steinberg D -
Pediatric Caries Risk Assessment as a Predictor of Caries Outcomes.
Pediatric dentistry 2017 Chaffee BW, Featherstone JDB, Zhan L -
Increased public reimbursement for prophylactic visits with dentists associated with increased receipt of preventive dental services in children.
Journal of public health dentistry 2017 Fisher-Owens SA, Amendola L, Featherstone JDB, Inge RE, Flaherman VJ -
Preventive Dental Care at 6-Month Intervals Is Associated With Reduced Caries Risk.
Clinical pediatrics 2017 Flaherman VJ, Epstein J, Amendola L, Inge R, Featherstone JD, Okumura M -
Development of a Core Curriculum Framework in Cariology for U.S. Dental Schools.
Journal of dental education 2016 Fontana M, Guzmán-Armstrong S, Schenkel AB, Allen KL, Featherstone J, Goolsby S, Kanjirath P, Kolker J, Martignon S, Pitts N, Schulte A, Slayton RL, Young D, Wolff M -
Caries Risk Assessment Item Importance: Risk Designation and Caries Status in Children under Age 6.
JDR clinical and translational research 2016 Chaffee BW, Featherstone JD, Gansky SA, Cheng J, Zhan L -
Caries inhibition with a CO2 9.3 μm laser: An in vitro study.
Lasers in surgery and medicine 2016 Rechmann P, Rechmann BM, Groves WH, Le CQ, Rapozo-Hilo ML, Kinsel R, Featherstone JD -
Approximal and occlusal carious lesions: Restorative treatment decisions by California dentists.
Journal of the American Dental Association (1939) 2016 Rechmann P, Doméjean S, Rechmann BM, Kinsel R, Featherstone JD -
Sustained effects of blue light on Streptococcus mutans in regrown biofilm.
Lasers in medical science 2016 Cohen-Berneron J, Steinberg D, Featherstone JD, Feuerstein O -
Causal mediation analysis with multiple causally non-ordered mediators.
Statistical methods in medical research 2015 Taguri M, Featherstone J, Cheng J -
Non-operative anti-caries agents and dental caries increment among adults at high caries risk: a retrospective cohort study.
BMC oral health 2015 Chaffee BW, Cheng J, Featherstone JD -
Long-term adoption of caries management by risk assessment among dental students in a university clinic.
Journal of dental education 2015 Chaffee BW, Featherstone JD -
Performance of a light fluorescence device for the detection of microbial plaque and gingival inflammation.
Clinical oral investigations 2015 Rechmann P, Liou SW, Rechmann BM, Featherstone JD -
How do dental students determine patients' caries risk level using the Caries Management By Risk Assessment (CAMBRA) system?
Journal of dental education 2015 Doméjean S, Léger S, Rechmann P, White JM, Featherstone JD -
Baseline caries risk assessment as a predictor of caries incidence.
Journal of dentistry 2015 Chaffee BW, Cheng J, Featherstone JD -
Quality assurance study of caries risk assessment performance by clinical faculty members in a school of dentistry.
Journal of dental education 2014 Rechmann P, Featherstone JD -
Laser all-ceramic crown removal-a laboratory proof-of-principle study-phase 1 material characteristics.
Lasers in surgery and medicine 2014 Rechmann P, Buu NC, Rechmann BM, Le CQ, Finzen FC, Featherstone JD -
Understanding the chemistry of dental erosion.
Monographs in oral science 2014 Shellis RP, Featherstone JD, Lussi A -
Maintaining oral health across the life span.
The Nurse practitioner 2014 Jablonski R, Mertz E, Featherstone JD, Fulmer T -
Effects of CO2 laser irradiation on tooth enamel coated with biofilm.
Lasers in surgery and medicine 2014 Cohen J, Featherstone JD, Le CQ, Steinberg D, Feuerstein O -
In-vivo occlusal caries prevention by pulsed CO2 -laser and fluoride varnish treatment--a clinical pilot study.
Lasers in surgery and medicine 2013 Rechmann P, Charland DA, Rechmann BM, Le CQ, Featherstone JD -
Changes in gene expression of Streptococcus mutans in planktonic environment following CO2 laser irradiation.
Photomedicine and laser surgery 2013 Sol A, Steinberg D, Featherstone JD, Feuerstein O -
Caries management by risk assessment.
Community dentistry and oral epidemiology 2013 Young DA, Featherstone JD -
Caries management pathways preserve dental tissues and promote oral health.
Community dentistry and oral epidemiology 2013 Ismail AI, Tellez M, Pitts NB, Ekstrand KR, Ricketts D, Longbottom C, Eggertsson H, Deery C, Fisher J, Young DA, Featherstone JD, Evans W, Zeller GG, Zero D, Martignon S, Fontana M, Zandona A -
Risk assessment - can we achieve consensus?
Community dentistry and oral epidemiology 2013 Twetman S, Fontana M, Featherstone JD -
Minimal intervention dentistry: part 1. From 'compulsive' restorative dentistry to rational therapeutic strategies.
British dental journal 2012 Featherstone JD, Doméjean S -
Caries detection using light-based diagnostic tools.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2012 Rechmann P, Rechmann BM, Featherstone JD -
The role of remineralizing and anticaries agents in caries management.
Advances in dental research 2012 Featherstone JD, Doméjean S -
Influence of blue light on Streptococcus mutans re-organization in biofilm.
Journal of photochemistry and photobiology. B, Biology 2012 Chebath-Taub D, Steinberg D, Featherstone JD, Feuerstein O -
Factors related to maternal transmission of mutans streptococci in high-risk children-pilot study.
Pediatric dentistry 2012 Zhan L, Tan S, Den Besten P, Featherstone JD, Hoover CI -
Performance of laser fluorescence devices and visual examination for the detection of occlusal caries in permanent molars.
Journal of biomedical optics 2012 Rechmann P, Charland D, Rechmann BM, Featherstone JD -
Mother and youth access (MAYA) maternal chlorhexidine, counselling and paediatric fluoride varnish randomized clinical trial to prevent early childhood caries.
International journal of paediatric dentistry 2011 Ramos-Gomez FJ, Gansky SA, Featherstone JD, Jue B, Gonzalez-Beristain R, Santo W, Martinez E, Weintraub JA -
Changing the face and practice of dentistry: a 10-year plan.
Journal of the California Dental Association 2011 Young D, Ricks CS, Featherstone JD, Fontana M, Fournier SM, Geiermann SP, Hurlbutt M, Kutsch VK, Loftus R, Luther JR, Nový BB, Wolff MS, Wong A -
Recommendation for a non-animal alternative to rat caries testing.
American journal of dentistry 2011 Featherstone JD, Stookey GK, Kaminski MA, Faller RV -
The Featherstone laboratory pH cycling model: a prospective, multi-site validation exercise.
American journal of dentistry 2011 Stookey GK, Featherstone JD, Rapozo-Hilo M, Schemehorn BR, Williams RA, Baker RA, Barker ML, Kaminski MA, McQueen CM, Amburgey JS, Casey K, Faller RV -
Validation of the CDA CAMBRA caries risk assessment--a six-year retrospective study.
Journal of the California Dental Association 2011 Doméjean S, White JM, Featherstone JD -
A view from both sides.
Journal of the California Dental Association 2011 Featherstone JD -
Caries inhibition in vital teeth using 9.6-μm CO2-laser irradiation.
Journal of biomedical optics 2011 Rechmann P, Fried D, Le CQ, Nelson G, Rapozo-Hilo M, Rechmann BM, Featherstone JD -
Caries risk assessment and management for the prosthodontic patient.
Journal of prosthodontics : official journal of the American College of Prosthodontists 2011 Featherstone JD, Singh S, Curtis DA -
Caries risk assessment, prevention, and management in pediatric dental care.
General dentistry 2010 Ramos-Gomez F, Crystal YO, Ng MW, Tinanoff N, Featherstone JD -
Pediatric dental care: prevention and management protocols based on caries risk assessment.
Journal of the California Dental Association 2010 Ramos-Gomez FJ, Crystal YO, Ng MW, Crall JJ, Featherstone JD -
Social inequalities in childhood dental caries: the convergent roles of stress, bacteria and disadvantage.
Social science & medicine (1982) 2010 Boyce WT, Den Besten PK, Stamperdahl J, Zhan L, Jiang Y, Adler NE, Featherstone JD -
Implementing caries risk assessment and clinical interventions.
Dental clinics of North America 2010 Young DA, Featherstone JD -
Horizontal transmission of mutans streptococci in children.
Journal of dental research 2010 Doméjean S, Zhan L, DenBesten PK, Stamper J, Boyce WT, Featherstone JD -
Randomized controlled clinical trial on the evaluation of bacteriostatic and cariostatic effects of a novel povidone-iodine/fluoride foam in children with high caries risk.
Quintessence international (Berlin, Germany : 1985) 2009 Xu X, Li JY, Zhou XD, Xie Q, Zhan L, Featherstone JD -
An Automated Digital Microradiography System for Assessing Tooth Demineralization.
Proceedings of SPIE--the International Society for Optical Engineering 2009 Darling CL, Le CQ, Featherstone JD, Fried D -
Remineralization, the natural caries repair process--the need for new approaches.
Advances in dental research 2009 Featherstone JD -
In vitro evaluation of erbium, chromium:yttrium-scandium-gallium-garnet laser-treated enamel demineralization.
Lasers in medical science 2008 de Freitas PM, Rapozo-Hilo M, Eduardo Cde P, Featherstone JD -
Genetic and physiological effects of noncoherent visible light combined with hydrogen peroxide on Streptococcus mutans in biofilm.
Antimicrobial agents and chemotherapy 2008 Steinberg D, Moreinos D, Featherstone J, Shemesh M, Feuerstein O -
Caries management by risk assessment: implementation guidelines.
Journal of the California Dental Association 2007 Young DA, Featherstone JD, Roth JR, Anderson M, Autio-Gold J, Christensen GJ, Fontana M, Kutsch VK, Peters MC, Simonsen RJ, Wolff MS -
Dental students' knowledge, attitudes, and intended behaviors regarding caries risk assessment: impact of years of education and patient age.
Journal of dental education 2007 Calderón SH, Gilbert P, Zeff RN, Gansky SA, Featherstone JD, Weintraub JA, Gerbert B -
Caries risk assessment appropriate for the age 1 visit (infants and toddlers).
Journal of the California Dental Association 2007 Ramos-Gomez FJ, Crall J, Gansky SA, Slayton RL, Featherstone JD -
Caries risk assessment in practice for age 6 through adult.
Journal of the California Dental Association 2007 Featherstone JD, Domejean-Orliaguet S, Jenson L, Wolff M, Young DA -
Clinical protocols for caries management by risk assessment.
Journal of the California Dental Association 2007 Jenson L, Budenz AW, Featherstone JD, Ramos-Gomez FJ, Spolsky VW, Young DA -
Curing the silent epidemic: caries management in the 21st century and beyond.
Journal of the California Dental Association 2007 Young DA, Featherstone JD, Roth JR -
Caries risk assessment in an educational environment.
Journal of dental education 2006 Doméjean-Orliaguet S, Gansky SA, Featherstone JD -
Dissolution studies of bovine dental enamel surfaces modified by high-speed scanning ablation with a lambda = 9.3-microm TEA CO(2) laser.
Lasers in surgery and medicine 2006 Fried D, Featherstone JD, Le CQ, Fan K -
Delivery challenges for fluoride, chlorhexidine and xylitol.
BMC oral health 2006 Featherstone JD -
Comparative calcium binding of leucine-rich amelogenin peptide and full-length amelogenin.
European journal of oral sciences 2006 Le TQ, Gochin M, Featherstone JD, Li W, DenBesten PK -
Caries prevention and reversal based on the caries balance.
Pediatric dentistry 2006 Featherstone JD -
Antibacterial treatment needed for severe early childhood caries.
Journal of public health dentistry 2006 Zhan L, Featherstone JD, Gansky SA, Hoover CI, Fujino T, Berkowitz RJ, Den Besten PK -
Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography.
Journal of biomedical optics 2006 Jones RS, Darling CL, Featherstone JD, Fried D -
Cariogenic virulence characteristics of mutans streptococci isolated from caries-active and caries-free adults.
Journal of the California Dental Association 2005 Khoo G, Zhan L, Hoover C, Featherstone JD -
Digital imaging fiber-optic trans-illumination, F-speed radiographic film and depth of approximal lesions.
Journal of the American Dental Association (1939) 2005 Young DA, Featherstone JD -
Prevention of enamel demineralization: an in-vitro study using light-cured filled sealant.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2005 Hu W, Featherstone JD -
Early caries imaging and monitoring with near-infrared light.
Dental clinics of North America 2005 Fried D, Featherstone JD, Darling CL, Jones RS, Ngaotheppitak P, Bühler CM -
Anticaries potential of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2005 Pfarrer AM, McQueen CM, Lawless MA, Rapozo-Hilo M, Featherstone JD -
Salivary fluoride levels following application of fluoride varnish or fluoride rinse.
Community dentistry and oral epidemiology 2004 Eakle WS, Featherstone JD, Weintraub JA, Shain SG, Gansky SA -
Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention.
Lasers in surgery and medicine 2004 Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD -
The caries balance: the basis for caries management by risk assessment.
Oral health & preventive dentistry 2004 Featherstone JD -
Caries management by risk assessment: consensus statement, April 2002.
Journal of the California Dental Association 2003 Featherstone JD, Adair SM, Anderson MH, Berkowitz RJ, Bird WF, Crall JJ, Den Besten PK, Donly KJ, Glassman P, Milgrom P, Roth JR, Snow R, Stewart RE -
The caries balance: contributing factors and early detection.
Journal of the California Dental Association 2003 Featherstone JD -
In vivo inhibition of demineralization around orthodontic brackets.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2003 Gorton J, Featherstone JD -
Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin.
Lasers in surgery and medicine 2003 Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ -
Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography.
Journal of biomedical optics 2002 Fried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C -
Anticaries and hard tissue abrasion effects of a "dual-action" whitening, sodium hexametaphosphate tartar control dentifrice.
The Journal of clinical dentistry 2002 Pfarrer A, White D, Rapozo-Hilo M, Featherstone J -
Bacterial, behavioral and environmental factors associated with early childhood caries.
The Journal of clinical pediatric dentistry 2002 Ramos-Gomez FJ, Weintraub JA, Gansky SA, Hoover CI, Featherstone JD -
Thermal and chemical modification of dentin by 9-11-microm CO2 laser pulses of 5-100-micros duration.
Lasers in surgery and medicine 2002 Fried D, Zuerlein MJ, Le CQ, Featherstone JD -
Effect of metabolic acidosis on the potassium content of bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997 Bushinsky DA, Gavrilov K, Chabala JM, Featherstone JD, Levi-Setti R -
Magnesium-containing carbonate apatites.
Journal of inorganic biochemistry 1997 Mayer I, Schlam R, Featherstone JD -
Histomorphometric analysis of iliac crest bone biopsies in placebo-treated versus fluoride-treated subjects.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1995 Lundy MW, Stauffer M, Wergedal JE, Baylink DJ, Featherstone JD, Hodgson SF, Riggs BL -
A straightforward scanning electron microscopy technique for examining non-metal coated dental hard tissues.
Scanning microscopy 1991 McCormack SM, Tormo FJ, Featherstone JD -
Clinical evaluation of Fluroshield pit and fissure sealant.
Clinical preventive dentistry 1990 Jensen OE, Billings RJ, Featherstone JD