Joaquin Anguera, PhD
Associate Professor
Neurology
School of Medicine

Creating a unique line of research that built upon these domains has involved a strong interdisciplinary emphasis, with these efforts centered on healthy young and older adults, as well as clinical populations involving ADHD, autism, and depressed individuals amongst others. My current work leverages state-of-the-art technological approaches to create i) advanced training tools to remediate cognitive deficiencies (see our cover story in Nature, Anguera et al., 2013) and ii) use mobile technology to robustly characterizing individual abilities in each of these domains outside of the laboratory (contributed to the creation of 10 different mobile apps to date; see Anguera et al., 2016 as an example).

• The whole is greater than the sum of its parts: Using cognitive profiles to predict academic achievement.
  Trends in neuroscience and education 2024 Younger JW, Schaerlaeken S, Anguera JA, Gazzaley A, Project iLEAD Consortium
• Neurodegenerative disease pathways are perturbed in patients with cancer who self-report cognitive changes and anxiety: A pathway impact analysis.
  Cancer 2024 Oppegaard KR, Mayo SJ, Armstrong TS, Dokiparthi V, Melisko M, Levine JD, Olshen AB, Anguera JA, Roy R, Paul S, Cooper B, Conley YP, Hammer MJ, Miaskowski C, Kober KM
• Digital rhythm training improves reading fluency in children.
  Developmental science 2024 Zanto TP, Giannakopoulou A, Gallen CL, Ostrand AE, Younger JW, Anguera-Singla R, Anguera JA, Gazzaley A
• Adaptive video games for the assessment and rehabilitation of dementia.
  Alzheimer's & Dementia 2023 Florian Sander, Valeria Manera, Christine R. Krebs, Maylis Touya, Elia Luca Fischer, Traian Popa, Andrea Brioschi Brioschi Guevara, Joaquin A Anguera, Adam Gazzaley, Stefan Klöppel, Gilles Allali, …
• Adverse Childhood Experiences and Higher Levels of Stress Are Associated With the Co-occurrence of Cancer-Related Cognitive Impairment and Anxiety.
  Seminars in oncology nursing 2023 Oppegaard KR, Mayo SJ, Armstrong TS, Kober KM, Anguera J, Hammer MJ, Levine JD, Conley YP, Paul S, Cooper B, Miaskowski C
• Acceptability of the LetSync App Wireframes for an mHealth Intervention to Improve HIV Care Engagement and Treatment Among Black Partnered Sexual Minority Men: Findings from In-Depth Qualitative Interviews.
  JMIR formative research 2023 Becker N, Kim HC, Bright DJ, Williams Iii R, Anguera JA, Arnold EA, Saberi P, Neilands TB, Pollack LM, Tan JY
• Better together: novel methods for measuring and modeling development of executive function diversity while accounting for unity.
  Frontiers in human neuroscience 2023 Younger JW, O'Laughlin KD, Anguera JA, Bunge SA, Ferrer EE, Hoeft F, McCandliss BD, Mishra J, Rosenberg-Lee M, Gazzaley A, Uncapher MR
• Quantifying attention span across the lifespan.
  Frontiers in Cognition 2023 Simon AJ, Gallen CL, Ziegler DA, Mishra J, Marco EJ, Anguera JA, Gazzaley A
• Influence of game features on attention in adults.
  Frontiers in psychology 2023 Gallen CL, Schachtner JN, Anguera-Singla R, Anguera JA, Gazzaley A
• Author Correction: Enhancing attention in children using an integrated cognitive-physical videogame: A pilot study.
  NPJ digital medicine 2023 Anguera JA, Rowe MA, Volponi JJ, Elkurdi M, Jurigova B, Simon AJ, Anguera-Singla R, Gallen CL, Gazzaley A, Marco EJ
• An Evaluation of the Multifactorial Model of Cancer-Related Cognitive Impairment.
  Nursing research 2023 Oppegaard KR, Mayo SJ, Armstrong TS, Kober KM, Anguera JA, Wright F, Levine JD, Conley YP, Paul S, Cooper B, Miaskowski C
• Enhancing attention in children using an integrated cognitive-physical videogame: A pilot study.
  NPJ digital medicine 2023 Anguera JA, Rowe MA, Volponi JJ, Elkurdi M, Jurigova B, Simon AJ, Anguera-Singla R, Gallen CL, Gazzaley A, Marco EJ
• A virtual reality program to assess cognitive function in multiple sclerosis: A pilot study.
  Frontiers in human neuroscience 2023 Hsu WY, Anguera JA, Rizzo A, Campusano R, Chiaravalloti ND, DeLuca J, Gazzaley A, Bove RM
• The Multifactorial Model of Cancer-Related Cognitive Impairment.
  Oncology nursing forum 2023 Oppegaard KR, Mayo SJ, Armstrong TS, Anguera JA, Kober KM, Miaskowski C
• Contribution of sustained attention abilities to real-world academic skills in children.
  Scientific reports 2023 Gallen CL, Schaerlaeken S, Younger JW, Project iLEAD Consortium, Anguera JA, Gazzaley A
• Blood-based biomarkers of cancer-related cognitive impairment in non-central nervous system cancer: A scoping review.
  Critical reviews in oncology/hematology 2022 Oppegaard KR, Armstrong TS, Anguera JA, Kober KM, Kelly DL, Laister RC, Saligan LN, Ayala AP, Kuruvilla J, Alm MW, Byker WH, Miaskowski C, Mayo SJ
• Integrated cognitive and physical fitness training enhances attention abilities in older adults.
  npj aging 2022 Anguera JA, Volponi JJ, Simon AJ, Gallen CL, Rolle CE, Anguera-Singla R, Pitsch EA, Thompson CJ, Gazzaley A
• Real-world behavioral dataset from two fully remote smartphone-based randomized clinical trials for depression.
  Scientific data 2022 Pratap A, Homiar A, Waninger L, Herd C, Suver C, Volponi J, Anguera JA, Areán P
• Feasibility, engagement, and preliminary clinical outcomes of a digital biodata-driven intervention for anxiety and depression.
  Frontiers in digital health 2022 Tsirmpas C, Andrikopoulos D, Fatouros P, Eleftheriou G, Anguera JA, Kontoangelos K, Papageorgiou C
• Leveraging technology to personalize cognitive enhancement methods in aging.
  Nature aging 2022 Ziegler DA, Anguera JA, Gallen CL, Hsu WY, Wais PE, Gazzaley A
• Multimodal Biosensing for Vestibular Network-Based Cybersickness Detection.
  IEEE journal of biomedical and health informatics 2022 Li G, McGill M, Brewster S, Chen CP, Anguera JA, Gazzaley A, Pollick F
• Enhancing neural markers of attention in children with ADHD using a digital therapeutic.
  PloS one 2021 Gallen CL, Anguera JA, Gerdes MR, Simon AJ, Cañadas E, Marco EJ
• Assessing Cognitive Function in Multiple Sclerosis With Digital Tools: Observational Study.
  Journal of medical Internet research 2021 Hsu WY, Rowles W, Anguera JA, Anderson A, Younger JW, Friedman S, Gazzaley A, Bove R
• Cancer-related cognitive impairment is associated with perturbations in inflammatory pathways.
  Cytokine 2021 Oppegaard K, Harris CS, Shin J, Paul SM, Cooper BA, Chan A, Anguera JA, Levine J, Conley Y, Hammer M, Miaskowski CA, Chan RJ, Kober KM
• Linking inhibitory control to math achievement via comparison of conflicting decimal numbers.
  Cognition 2021 Coulanges L, Abreu-Mendoza RA, Varma S, Uncapher MR, Gazzaley A, Anguera J, Rosenberg-Lee M
• A digital intervention targeting cognitive control network dysfunction in middle age and older adults with major depression.
  Translational psychiatry 2021 Gunning FM, Anguera JA, Victoria LW, Areán PA
• Long-term maintenance of multitasking abilities following video game training in older adults.
  Neurobiology of aging 2021 Anguera JA, Schachtner JN, Simon AJ, Volponi J, Javed S, Gallen CL, Gazzaley A
• Sustained benefits of cognitive training in children with inattention, three-year follow-up.
  PloS one 2021 Jurigova BG, Gerdes MR, Anguera JA, Marco EJ
• Score-based tests for detecting heterogeneity in linear mixed models.
  Behavior research methods 2021 Wang T, Merkle EC, Anguera JA, Turner BM
• Correction: Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study.
  Journal of medical Internet research 2021 Hsu WY, Rowles W, Anguera JA, Zhao C, Anderson A, Alexander A, Sacco S, Henry R, Gazzaley A, Bove R
• Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study.
  Journal of medical Internet research 2021 Hsu WY, Rowles W, Anguera JA, Zhao C, Anderson A, Alexander A, Sacco S, Henry R, Gazzaley A, Bove R
• Psychological Symptoms and Stress Are Associated With Decrements in Attentional Function in Cancer Patients Undergoing Chemotherapy.
  Cancer nursing 2020 Atallah M, Cooper B, Muñoz RF, Paul SM, Anguera J, Levine JD, Hammer M, Wright F, Chen LM, Melisko M, Conley YP, Miaskowski C, Dunn LB
• A novel in-home digital treatment to improve processing speed in people with multiple sclerosis: A pilot study.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Bove R, Rowles W, Zhao C, Anderson A, Friedman S, Langdon D, Alexander A, Sacco S, Henry R, Gazzaley A, Feinstein A, Anguera JA
• Enhanced Attention Using Head-mounted Virtual Reality.
  Journal of cognitive neuroscience 2020 Li G, Anguera JA, Javed SV, Khan MA, Wang G, Gazzaley A
• MOBILE COGNITIVE INTERVENTION IN OLDER VETERANS WITH TRAUMATIC BRAIN INJURY: RESULTS FROM THE BRAVE (BRAIN AGING IN VETERANS) TRAINING PILOT STUDY.
  Alzheimer's & Dementia 2019 Allison R. Kaup, Jessica Schachtner, Amy L. Byers, Deborah E. Barnes, Joaquin A. Anguera, Alexandrea L. Harmell, Maria-Paulina Amaya, Margaret Gross, Kristine Yaffe
• Closed-loop digital meditation improves sustained attention in young adults.
  Nature human behaviour 2019 Ziegler DA, Simon AJ, Gallen CL, Skinner S, Janowich JR, Volponi JJ, Rolle CE, Mishra J, Kornfield J, Anguera JA, Gazzaley A
• Maximal Oxygen Uptake Responders Versus Non-responders Show Differing Cognitive Responses to Movement-based Video Game Training.
  Medicine & Science in Sports & Exercise 2019 Christian Thompson, Brigid Larkin, Josh Volponi, Alexander Simon, Joaquin Anguera, Adam Gazzaley
• White Matter Microstructure Associations of Cognitive and Visuomotor Control in Children: A Sensory Processing Perspective.
  Frontiers in integrative neuroscience 2019 Brandes-Aitken A, Anguera JA, Chang YS, Demopoulos C, Owen JP, Gazzaley A, Mukherjee P, Marco EJ
• A Videogame-Based Digital Therapeutic to Improve Processing Speed in People with Multiple Sclerosis: A Feasibility Study.
  Neurology and therapy 2018 Bove RM, Rush G, Zhao C, Rowles W, Garcha P, Morrissey J, Schembri A, Alailima T, Langdon D, Possin K, Gazzaley A, Feinstein A, Anguera J
• The accuracy of passive phone sensors in predicting daily mood.
  Depression and anxiety 2018 Pratap A, Atkins DC, Renn BN, Tanana MJ, Mooney SD, Anguera JA, Areán PA
• Comparing Approaches to Mobile Depression Assessment for Measurement-Based Care: Prospective Study.
  Journal of medical Internet research 2018 Bauer AM, Baldwin SA, Anguera JA, Areán PA, Atkins DC
• Characterizing cognitive and visuomotor control in children with sensory processing dysfunction and autism spectrum disorders.
  Neuropsychology 2018 Brandes-Aitken A, Anguera JA, Rolle CE, Desai SS, Demopoulos C, Skinner SN, Gazzaley A, Marco EJ
• 3.27 Assessing White Matter Correlates of Cognitive and Visuomotor Control Deficits in Children With Sensory Processing Disorders.
  Journal of the American Academy of Child & Adolescent Psychiatry 2017 Annie Brandes-Aitken, Joaquin A. Anguera, Yi-Shin Chang, Julia P. Owen, Pratik Mukherjee, Elysa J. Marco
• Assessing Depression in the Wild: Insights From Two Large-Scale Fully Mobile Randomized Clinical Trials.
  Iproceedings 2017 Abhishek Pratap, Joaquin A Anguera, Brenna N Renn, Joshua Volponi, David C Atkins, Sean D Mooney, Pat A Areán
• Enhancing Spatial Attention and Working Memory in Younger and Older Adults.
  Journal of cognitive neuroscience 2017 Rolle CE, Anguera JA, Skinner SN, Voytek B, Gazzaley A
• 0749 SLEEP LOADING IMPROVES VISUAL SEARCH RESPONSE TIME AND REDUCES FATIGUE IN PROFESSIONAL BASEBALL PLAYERS.
  Sleep 2017 CD Mah, JA Anguera, A Gazzaley, A Luke
• The feasibility, acceptability, and outcomes of PRIME-D: A novel mobile intervention treatment for depression.
  Depression and anxiety 2017 Schlosser DA, Campellone TR, Truong B, Anguera JA, Vergani S, Vinogradov S, Arean P
• Improving late life depression and cognitive control through the use of therapeutic video game technology: A proof-of-concept randomized trial.
  Depression and anxiety 2017 Anguera JA, Gunning FM, Areán PA
• Characterizing cognitive control abilities in children with 16p11.2 deletion using adaptive 'video game' technology: a pilot study.
  Translational psychiatry 2016 Anguera JA, Brandes-Aitken AN, Rolle CE, Skinner SN, Desai SS, Bower JD, Martucci WE, Chung WK, Sherr EH, Marco EJ
• Mobile Assessment of Depression Treatment Response: Recruitment Challenges and Possible Solutions.
  Journal of Patient-Centered Research and Reviews 2016 Ashli A Owen-Smith, Michelle Panneton, Patricia Arean, Joaquin A Anguera, Shelby Reetz, Greg N Clarke
• Mood Disorders in Late Life.
  2016 Pat Arean, Eric Lenze, Joaquin A. Anguera
• Physiological And Cognitive Adaptations To 8 Weeks Of Training On A Movement-based Video Game.
  Medicine & Science in Sports & Exercise 2016 Christian Thompson, Caleb Khan, Leticia Whitton-Martinez, Josh Volpini, Juliana Souza, Alexander Simon, Sasha Skinner, Daniel Kingsbook, Alan Leggitt, Joaquin Anguera, Adam Gazzaley
• Conducting a fully mobile and randomised clinical trial for depression: access, engagement and expense.
  BMJ innovations 2016 Anguera JA, Jordan JT, Castaneda D, Gazzaley A, Areán PA
• Video games, cognitive exercises, and the enhancement of cognitive abilities.
  Current Opinion in Behavioral Sciences 2015 Joaquin A Anguera, Adam Gazzaley
• Delayed enhancement of multitasking performance: Effects of anodal transcranial direct current stimulation on the prefrontal cortex.
  Cortex; a journal devoted to the study of the nervous system and behavior 2015 Hsu WY, Zanto TP, Anguera JA, Lin YY, Gazzaley A
• Age-equivalent top-down modulation during cross-modal selective attention.
  Journal of cognitive neuroscience 2014 Guerreiro MJ, Anguera JA, Mishra J, Van Gerven PW, Gazzaley A
• Reconciling the influence of task-set switching and motor inhibition processes on stop signal after-effects.
  Frontiers in psychology 2013 Anguera JA, Lyman K, Zanto TP, Bollinger J, Gazzaley A
• A cognitive framework for understanding and improving interference resolution in the brain.
  Progress in brain research 2013 Mishra J, Anguera JA, Ziegler DA, Gazzaley A
• Aging Effects on Motor Learning.
  2012 Joaquin A. Anguera, Jin Bo, Rachael D. Seidler
• Neurocognitive contributions to motor skill learning: the role of working memory.
  Journal of motor behavior 2012 Seidler RD, Bo J, Anguera JA
• The effects of working memory resource depletion and training on sensorimotor adaptation.
  Behavioural brain research 2011 Anguera JA, Bernard JA, Jaeggi SM, Buschkuehl M, Benson BL, Jennett S, Humfleet J, Reuter-Lorenz PA, Jonides J, Seidler RD
• A model of healthy aging and motor inhibition in the basal ganglia.
  BMC Neuroscience 2011 Kyle Lyman, Joaquin Anguera, David Terman
• Dissociation of motor and sensory inhibition processes in normal aging.
  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2011 Anguera JA, Gazzaley A
• Age differences in callosal contributions to cognitive processes.
  Neuropsychologia 2011 Fling BW, Chapekis M, Reuter-Lorenz PA, Anguera J, Bo J, Langan J, Welsh RC, Seidler RD
• A spatial explicit strategy reduces error but interferes with sensorimotor adaptation.
  Journal of neurophysiology 2011 Benson BL, Anguera JA, Seidler RD
• Failure to engage spatial working memory contributes to age-related declines in visuomotor learning.
  Journal of cognitive neuroscience 2011 Anguera JA, Reuter-Lorenz PA, Willingham DT, Seidler RD
• Contributions of spatial working memory to visuomotor learning.
  Journal of cognitive neuroscience 2010 Anguera JA, Reuter-Lorenz PA, Willingham DT, Seidler RD
• Plastic changes in hand proprioception following force-field motor learning.
  Journal of neurophysiology 2010 Goble DJ, Anguera JA
• A mathematical model of human inhibitory control.
  BMC Neuroscience 2010 Kyle Lyman, Joaquin Anguera, Adam Gazzaley, David Terman
• Changes in performance monitoring during sensorimotor adaptation.
  Journal of neurophysiology 2009 Anguera JA, Seidler RD, Gehring WJ
• Neural correlates associated with intermanual transfer of sensorimotor adaptation.
  Brain research 2007 Anguera JA, Russell CA, Noll DC, Seidler RD
• Motor Control.
  Encyclopedia of Gerontology 2007 R.D. Seidler, A.S. Bangert, J.A. Anguera, C.M. Quinn-Walsh