Joanna Kovalski, PhD
Associate Specialist
Urology
School of Medicine

Publications (16)

Top publication keywords:
Protein BiosynthesisNeoplasmsRNA, MessengerCell Transformation, NeoplasticMetabolomicsGene Expression Regulation, NeoplasticCarcinoma, Pancreatic DuctalRNA-Binding ProteinsOncogenesProto-Oncogene Proteins c-mycProteome5' Untranslated RegionsMechanistic Target of Rapamycin Complex 2Pancreatic Neoplasmsras Proteins

• Programmable translational inhibition by a molecular glue-oligonucleotide conjugate.
  bioRxiv : the preprint server for biology 2025 Wang S, Kovalski JR, Zapatero-Belinchón FJ, Bennett M, Kuzuoglu-Öztürk D, Li Q, Stevenson E, Liu J, Krogan NJ, Ott M, Swaney DL, Ruggero D, Lou K, Shokat KM
• Breaking up translation condensates in cancer.
  Nature cell biology 2025 Kovalski JR, Ruggero D
• Functional screen identifies RBM42 as a mediator of oncogenic mRNA translation specificity.
  Nature cell biology 2025 Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D
• Functional screen for mediators of onco-mRNA translation specificity.
  bioRxiv : the preprint server for biology 2024 Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D
• Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.
  Nature communications 2023 Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara-…

Show all (11 more) Hide

• Protein synthesis control in cancer: selectivity and therapeutic targeting.
  The EMBO journal 2022 Kovalski JR, Kuzuoglu-Ozturk D, Ruggero D
• Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer.
  Methods in molecular biology (Clifton, N.J.) 2021 Kovalski JR, Xu Y, Ruggero D
• KRAS regulation by small non-coding RNAs and SNARE proteins.
  Nature communications 2019 Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA
• Ras functional proximity proteomics establishes mTORC2 as new direct ras effector.
  Oncotarget 2019 Kovalski JR, Shanderson RL, Khavari PA
• The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.
  Molecular cell 2019 Kovalski JR, Bhaduri A, Zehnder AM, Neela PH, Che Y, Wozniak GG, Khavari PA
• RNA-protein interaction detection in living cells.
  Nature methods 2018 Ramanathan M, Majzoub K, Rao DS, Neela PH, Zarnegar BJ, Mondal S, Roth JG, Gai H, Kovalski JR, Siprashvili Z, Palmer TD, Carette JE, Khavari PA
• Three-Dimensional Human Skin Models to Understand Staphylococcus aureus Skin Colonization and Infection.
  Frontiers in immunology 2014 Popov L, Kovalski J, Grandi G, Bagnoli F, Amieva MR
• Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition.
  Genome research 2014 Webster DE, Barajas B, Bussat RT, Yan KJ, Neela PH, Flockhart RJ, Kovalski J, Zehnder A, Khavari PA
• BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration.
  Genome research 2012 Flockhart RJ, Webster DE, Qu K, Mascarenhas N, Kovalski J, Kretz M, Khavari PA
• VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Oladipupo S, Hu S, Kovalski J, Yao J, Santeford A, Sohn RE, Shohet R, Maslov K, Wang LV, Arbeit JM
• Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
  Blood 2011 Oladipupo SS, Hu S, Santeford AC, Yao J, Kovalski JR, Shohet RV, Maslov K, Wang LV, Arbeit JM