James Padbury, MD
Professor
Pediatrics
School of Medicine
As a senior neonatologist, I have participated consistently in independent research, leadership, administration and management at each of the of my academic appointments. This has included executive committee service, financial leadership and oversight, and service on search committees.
Awards
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- Certificate of National Research Mentor, National Research Mentoring Network, 2019
- Editorial Board Certificate of Excellence, Journal of Pediatrics, 2018
- Mentor of the Year, Eastern Society for Pediatric Research, 2014
- Volunteer of the Year Award, March of Dimes Rhode Island Chapter, 2009
- National Distinguished Volunteer Service Award, National Foundation March of Dime, 2008
- Jonas Salk Health Leadership Award for Healthcare Providers, March of Dimes Rhode Island Chapter, 2004
- Medical Staff Distinguished Service Award, Women & Infants Hospital of RI, 2004
- Basil O’Connor Research Scholar Award, National Foundation March of Dimes, 1984
- Richard E. Weitzman, M.D. Memorial Endocrinology Research Award, Harbor - UCLA Medical Center, 1981
- Magna Cum Laude, University of California Irvine, 1969
Education & Training
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- Fellowship Neonatal-Perinatal Medicine Harbor - UCLA Medical Center 1981
- Chief Resident Pediatrics University of California San Francisco 1977
- Residency Pediatrics Boston Children's Hospital Medical Center 1976
- Fellowship Neonatal-Perinatal Medicine Boston Children's Hospital Medical Center 1975
- Internship Pediatrics University of California San Francisco 1974
- MD Medicine University of California Los Angeles 1973
- BS Biological Science University of California Irvine 1969
Interests
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- fetal physiology
- cardiovascular & placental developmental biology and perinatal genetics
Grants and Projects
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- Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis, NIAID, 2024-2027
- Advance Clinical and Translational Research (Advance-CTR), NIH, 2016-2026
- Environmental Influences on Neurodevelopmental Outcome in Infants Born Very Preterm, NIH/DO, 2016-2025
- Center for Molecular Epidemiology, NIH/NIGMS, 2013-2023
- Center of Biomedical Research Excellence (COBRE) for Reproductive Health, NIH, 2017-2022
- Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis, NIH/NIAID, 2019-2021
- RI Center for Clinical and Translational Sciences Award (IDEA CTR), NIH/NIGMS, 2016-2021
- COBRE for Perinatal Biology, NIH, 2015-2021
- Center of Biomedical Research Excellence (COBRE) for the Computational Biology and Human Disease, NIH/NIGMS, 2016-2021
- Center of Biomedical Research Excellence (COBRE) in Perinatal Biology, NIH/NCRR, 2003-2020
- Center of Biomedical Research Excellence (COBRE) in Perinatal Biology, NIH/NIGMS, 2015-2020
- Effects of Placental Transfusion on Early Brain Development, NIH, 2012-2018
- Epigenetic Predictors of Impairment in Very Preterm Infants, NIH/NICHD, 2016-2018
- Adrenal function and adverse CV outcomes at age 6 after extremely preterm birth, NIH/NICHD, 2013-2017
- Effects of Placental Transfusion on Early Brain Development, NIH/NICHD, 2012-2017
- Bioinformatics and Directed Resequencing in Preterm Birth, National Foundation March of Dimes, 2014-2017
- Maternal smoking: HPA and epigenetic pathways to infant neurobehavior deficits, NIH/NIDA, 2011-2016
- Epigenetics in Neurodevelopment and Mental Health, NIH/NIMH, 2011-2016
- Critical Congenital Heart Disease Newborn Screening Demonstration Program, HRSA, 2012-2015
- Rapid Detection of Neonatal Sepsis, NIH/NICHD, 2012-2014
- COBRE for Perinatal Biology, NIH, 2003-2014
- Fetal Genetic Contributions to Preeclampsia, NIH/NICHD, 2012-2014
- COBRE for Perinatal Biology, NIH, 2003-2013
- Engineering Replacement Tissues with Amniotic Stem Cells, DOD, 2010-2012
- Prenatal Smoking, Fetal Behavior and Infant Withdrawal, NIH/NIDA, 2005-2012
- Preterm Birth: A Novel Bioinformatics and Genomics Approach, National Foundation March of Dimes, 2009-2012
- Shared High-Throughput DNA Sequencer for the Brown University Community, NIH/NCRR, 2010
- Polymorphisms in IL-10 Locus Predispose to Preterm Birth, NIH/NICHD, 2001-2007
- Immune Programming of Gestational Diabetes, Gregg Diabetes in Pregnancy Award, American Diabetes Association, 2004-2006
- Therapeutic Use of Inter-Alpha Inhibitors in Sepsis, NIH/NIGMS, 2004-2006
- Perinatal Biology Training Grant, NIH/NICHD, 1999-2005
- Perinatal Biology Training Grant, NIH, 1999-2005
- The Biological Basis for Perinatal Transition, NIH/NICHD, 1997-2003
- Biological Basis for Perinatal Transition, NIH, 1977-2002
- Kilguss Research Institute, USDHS Health Resources Services Administration, 2001
- New Strategies to Mature the Premature Fetus, NIH/NICHD, 1998
- Fetal Neurochemical Effects of Cocaine, NIH, 1993-1997
- Neurochemical Effects of Cocaine in Fetal Sheep, NIH/NIDA, 1993-1996
- Catecholamine Physiology and Newborn Adaptation, NIH, 1984-1993
- Catecholamine Physiology and Newborn Adaptation, NIH/NICHD, 1984-1993
- ENDOGENOUS OPIATES, NIH, 1987-1990
- ENDOGENOUS OPIATES, NIH/NICHD, 1987-1990
- Investigative Group Fellowship Award, American Heart Association, 1987-1990
- Dobutamine Pharmacokinetics and Cardiovascular Responses in Neonates, li Lily, Inc, 1988-1990
- Basil O’Connor Research Grant, National Foundation March of Dimes, 1984-1987
Publications (262)
Top publication keywords:
PlacentaPlacental CirculationDNA MethylationInfant BehaviorUmbilical CordAlpha-Globulins11-beta-Hydroxysteroid Dehydrogenase Type 2Infant, NewbornPre-EclampsiaIntensive Care Units, NeonatalReceptors, Adrenergic, beta-1Premature BirthSheepNorepinephrineInfant, Premature
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Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy.
Experimental & molecular medicine 2024 Huang Z, Cheng S, Jash S, Fierce J, Agudelo A, Higashiyama T, Hanna N, Nakashima A, Saito S, Padbury J, Schuster J, Sharma S -
Hypertensive disorders of pregnancy and subsequent risk of Alzheimer's disease and other dementias.
Alzheimer's & dementia (Amsterdam, Netherlands) 2023 Schliep KC, Shaaban CE, Meeks H, Fraser A, Smith KR, Majersik JJ, Foster NL, Wactawski-Wende J, Østbye T, Tschanz J, Padbury JF, Sharma S, Zhang Y, Facelli JC, Abdelrahman CS, Theilen L, Varner MW -
Febrile preemies in the ED.
The Journal of pediatrics 2023 Padbury J -
Clinical impact of severe acute kidney injury on post-operative and brain injury outcomes in preterm infants following surgical necrotizing enterocolitis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Garg PM, Paschal JL, Zhang M, Pippins M, Taylor C, Sanderson K, Reddy K, Askenazi D, Padbury JF, Hillegass WB -
Evaluating systemic changes to support clinical and translational health research.
Evaluation and program planning 2022 Kimberly JA, Fede J, Kogut S, Stranieri G, Hayward AR, Stevenson JF, Padbury J
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Protein Network Analysis of Whole Exome Sequencing of Severe Preeclampsia.
Frontiers in genetics 2022 Schuster J, Tollefson GA, Zarate V, Agudelo A, Stabila J, Ragavendran A, Padbury J, Uzun A -
A core of differentially methylated CpG loci in gMDSCs isolated from neonatal and adult sources.
Clinical epigenetics 2022 Berglund-Brown I, Nissen E, Koestler DC, Butler RA, Eliot MN, Padbury JF, Salas LA, Molinaro AM, Christensen BC, Wiencke JK, Kelsey KT -
Protein interaction networks define the genetic architecture of preterm birth.
Scientific reports 2022 Uzun A, Schuster JS, Stabila J, Zarate V, Tollefson GA, Agudelo A, Kothiyal P, Wong WSW, Padbury J -
Effects of Pharmacologic Treatment for Neonatal Abstinence Syndrome on DNA Methylation and Neurobehavior: A Prospective Cohort Study.
The Journal of pediatrics 2021 Camerota M, Davis JM, Dansereau LM, Oliveira EL, Padbury JF, Lester BM -
NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants.
Aging 2021 Graw S, Camerota M, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, DellaGrotta SA, Dansereau LM, Padbury JF, O'Shea M, Lester BM, Marsit CJ, Everson TM -
Novel blood test for early biomarkers of preeclampsia and Alzheimer's disease.
Scientific reports 2021 Cheng S, Banerjee S, Daiello LA, Nakashima A, Jash S, Huang Z, Drake JD, Ernerudh J, Berg G, Padbury J, Saito S, Ott BR, Sharma S -
An E-Textile Respiration Sensing System for NICU Monitoring: Design and Validation.
Journal of signal processing systems 2021 Cay G, Ravichandran V, Saikia MJ, Hoffman L, Laptook A, Padbury J, Salisbury AL, Gitelson-Kahn A, Venkatasubramanian K, Shahriari Y, Mankodiya K -
50 Years Ago in TheJournalofPediatrics: An Ongoing Feat: Assessing Proper Endotracheal Tube Position in the Neonate.
The Journal of pediatrics 2021 Boudreau LE, Padbury JF -
DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function.
Pediatric research 2021 Padbury JF, Do BT, Bann CM, Marsit C, Hintz SR, Vohr BR, Lowe J, Newman JE, Granger DA, Payne A, Watterberg K, SUPPORT Study Group of the Eunice Kennedy Shriver National Institute of Child Health and … -
Advance-CTR: Statewide Infrastructure to Improve Health in Rhode Island through Clinical and Translational Research.
Rhode Island medical journal (2013) 2021 Zabala V, Stranieri G, Fournier H, Hawrot E, Padbury J -
Translational Research: The Time is Now.
Rhode Island medical journal (2013) 2021 Padbury JF, Cho BP -
50 Years Ago in TheJournalofPediatrics: Diazoxide-Induced Hyperosmolar Nonketotic Coma: Contemporary Genetic Insights.
The Journal of pediatrics 2021 Boudreau LE, Padbury JF -
Impact of NIH's Institutional Development Award (IDeA) Programs in Rhode Island.
Rhode Island medical journal (2013) 2021 Cho B, Padbury J -
Improving the quality and quantity of clinical and translational research statewide: An application of group concept mapping.
Journal of clinical and translational science 2021 Fede J, Kogut SJ, Hayward A, Stevenson JF, Willey-Temkin C, Fournier H, Stranieri G, Kimberly JA, Padbury J -
Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infants.
Clinical epigenetics 2020 Everson TM, O'Shea TM, Burt A, Hermetz K, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, Soliman A, DellaGrotta SA, Dansereau LM, Padbury JF, Lester BM, Marsit CJ -
Epigenome-wide analysis identifies genes and pathways linked to acoustic cry variation in preterm infants.
Pediatric research 2020 Aghagoli G, Sheinkopf SJ, Everson TM, Marsit CJ, Lee H, Burt AA, Carter BS, Helderman JB, Hofheimer JA, McGowan EC, Neal CR, O'Shea TM, Pastyrnak SL, Smith LM, Soliman A, Dansereau LM, DellaGrotta SA,… -
The Effects of Delayed Cord Clamping on 12-Month Brain Myelin Content and Neurodevelopment: A Randomized Controlled Trial.
American journal of perinatology 2020 Mercer JS, Erickson-Owens DA, Deoni SCL, Dean Iii DC, Tucker R, Parker AB, Joelson S, Mercer EN, Collins J, Padbury JF -
Proteinarium: Multi-sample protein-protein interaction analysis and visualization tool.
Genomics 2020 Armanious D, Schuster J, Tollefson GA, Agudelo A, DeWan AT, Istrail S, Padbury J, Uzun A -
Placental extracellular vesicles and pre-eclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989) 2020 Schuster J, Cheng SB, Padbury J, Sharma S -
DNA methylation in children with prenatal methamphetamine exposure and environmental adversity.
Pediatric research 2020 Oni-Orisan OO, Dansereau LM, Marsit CJ, Smith LM, Neal CR, Della Grotta SA, Padbury JF, Lester BM -
Get the most out of your data.
The Journal of pediatrics 2020 Padbury JF -
Social Stress-Related Epigenetic Changes Associated With Increased Heart Rate Variability in Infants.
Frontiers in behavioral neuroscience 2020 Aghagoli G, Conradt E, Padbury JF, Sheinkopf SJ, Tokadjian H, Dansereau LM, Tronick EZ, Marsit CJ, Lester BM -
Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia.
Autophagy 2019 Nakashima A, Cheng SB, Ikawa M, Yoshimori T, Huber WJ, Menon R, Huang Z, Fierce J, Padbury JF, Sadovsky Y, Saito S, Sharma S -
How old am I really?
The Journal of pediatrics 2019 Padbury JF -
VIVA (VIsualization of VAriants): A VCF File Visualization Tool.
Scientific reports 2019 Tollefson GA, Schuster J, Gelin F, Agudelo A, Ragavendran A, Restrepo I, Stey P, Padbury J, Uzun A -
Effect of prematurity on genome wide methylation in the placenta.
BMC medical genetics 2019 Schuster J, Uzun A, Stablia J, Schorl C, Mori M, Padbury JF -
Application of Whole Exome Sequencing in Congenital Secretory Diarrhea Diagnosis.
Journal of pediatric gastroenterology and nutrition 2019 Gupta A, Sanville J, Menz T, Warner N, Muise AM, Fiedler K, Martín MG, Padbury J, Phornphutkul C, Sanchez-Esteban J, Cerezo CS -
Epigenome-wide Analysis Identifies Genes and Pathways Linked to Neurobehavioral Variation in Preterm Infants.
Scientific reports 2019 Everson TM, Marsit CJ, Michael O'Shea T, Burt A, Hermetz K, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, Soliman A, DellaGrotta SA, Dansereau LM, Padbury JF, … -
Genetic disorders of lung development.
The Journal of pediatrics 2019 Padbury JF -
Large Scale Next Generation Sequencing and Newborn Screening: Are We Ready?
The Journal of pediatrics 2019 Phornphutkul C, Padbury J -
Doc, my tummy hurts.
The Journal of pediatrics 2019 Padbury JF -
Machine learning approach to literature mining for the genetics of complex diseases.
Database : the journal of biological databases and curation 2019 Schuster J, Superdock M, Agudelo A, Stey P, Padbury J, Sarkar IN, Uzun A -
Turning a negative into a positive.
The Journal of pediatrics 2018 Padbury JF -
Epigenetic Programming by Maternal Behavior in the Human Infant.
Pediatrics 2018 Lester BM, Conradt E, LaGasse LL, Tronick EZ, Padbury JF, Marsit CJ -
Newborn Screening for Hemoglobinopathies in Rhode Island, 2017.
Rhode Island medical journal (2013) 2018 Sprinz P, Lemke K, Padbury J, Farrow C -
Vitamin D and associated perinatal-neonatal outcomes among extremely low-birth-weight infants.
Journal of perinatology : official journal of the California Perinatal Association 2018 Shah BA, Padbury JF, Anderson MP, Holick MF, Szyld E, Gordon CM -
Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success.
The Journal of pediatrics 2018 Alvira CM, Steinhorn RH, Balistreri WF, Fineman JR, Oishi PE, Padbury JF, Kinsella JP, Abman SH -
Effects of Delayed Cord Clamping on 4-Month Ferritin Levels, Brain Myelin Content, and Neurodevelopment: A Randomized Controlled Trial.
The Journal of pediatrics 2018 Mercer JS, Erickson-Owens DA, Deoni SCL, Dean DC, Collins J, Parker AB, Wang M, Joelson S, Mercer EN, Padbury JF -
50 Years Ago in The Journal of Pediatrics: Platelet Counts in Healthy Premature Infants.
The Journal of pediatrics 2018 Gupta A, Padbury J -
Delayed Cord Clamping in Infants with Suspected Intrauterine Growth Restriction.
The Journal of pediatrics 2018 Wang M, Mercer JS, Padbury JF -
50 Years Ago in The Journal of Pediatrics: Human Cell Culture: An Important Tool for the Diagnosis and Understanding of Disease.
The Journal of pediatrics 2018 Benny MKV, Padbury J -
Clinical and Translational Research in Rhode Island: Results of a Needs Assessment Survey.
Rhode Island medical journal (2013) 2018 Willey C, Fede J, Stevenson J, Hayward A, Kogut S, Fournier H, Padbury J -
Better beginnings.
The Journal of pediatrics 2017 Padbury JF -
50 Years Ago in The Journal of Pediatrics: Cellular Growth of Human Placenta.
The Journal of pediatrics 2017 Bingham A, Padbury JF -
A novel, de novo mutation in the PRKAG2 gene: infantile-onset phenotype and the signaling pathway involved.
American journal of physiology. Heart and circulatory physiology 2017 Xu Y, Gray A, Hardie DG, Uzun A, Shaw S, Padbury J, Phornphutkul C, Tseng YT -
Effects of human umbilical cord blood mononuclear cells on respiratory system mechanics in a murine model of neonatal lung injury.
Experimental lung research 2017 Mills DR, Mao Q, Chu S, Falcon Girard K, Kraus M, Padbury JF, De Paepe ME -
Neutralizing anti-interleukin-1β antibodies reduce ischemia-related interleukin-1β transport across the blood-brain barrier in fetal sheep.
Neuroscience 2017 Patra A, Chen X, Sadowska GB, Zhang J, Lim YP, Padbury JF, Banks WA, Stonestreet BS -
Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial.
Journal of perinatology : official journal of the California Perinatal Association 2016 Mercer JS, Erickson-Owens DA, Collins J, Barcelos MO, Parker AB, Padbury JF -
Prenatal Major Depressive Disorder, Placenta Glucocorticoid and Serotonergic Signaling, and Infant Cortisol Response.
Psychosomatic medicine 2016 Stroud LR, Papandonatos GD, Parade SH, Salisbury AL, Phipps MG, Lester BM, Padbury JF, Marsit CJ -
Blood Level of Inter-Alpha Inhibitor Proteins Distinguishes Necrotizing Enterocolitis From Spontaneous Intestinal Perforation.
The Journal of pediatrics 2016 Shah BA, Migliori A, Kurihara I, Sharma S, Lim YP, Padbury J -
Gasping for air.
The Journal of pediatrics 2016 Padbury JF -
Medical morbidities and DNA methylation of NR3C1 in preterm infants.
Pediatric research 2016 Giarraputo J, DeLoach J, Padbury J, Uzun A, Marsit C, Hawes K, Lester B -
Lymphocyte genetic diversity revealed by next generation sequencing.
The Journal of pediatrics 2016 Padbury JF -
18-Month Follow-Up of Infants Cared for in a Single-Family Room Neonatal Intensive Care Unit.
The Journal of pediatrics 2016 Lester BM, Salisbury AL, Hawes K, Dansereau LM, Bigsby R, Laptook A, Taub M, Lagasse LL, Vohr BR, Padbury JF -
Structural and genomic variation in preterm birth.
Pediatric research 2016 Uzun A, Sahin Y, Schuster JS, Zheng X, Ryckman K, Feingold E, Padbury J -
Targeted Sequencing and Meta-Analysis of Preterm Birth.
PloS one 2016 Uzun A, Schuster J, McGonnigal B, Schorl C, Dewan A, Padbury J -
The developmental expression of the CDK inhibitor p57(kip2) (Cdkn1c) in the early mouse placenta.
Molecular reproduction and development 2016 Saunders AC, McGonnigal B, Uzun A, Padbury J -
Temporal Profile of Early Pulmonary Hypertension in Preterm Infants.
American journal of perinatology 2016 Mirza H, Ziegler J, Ford S, Padbury J, Tucker R, Laptook A -
Prenatal Programming of Infant Neurobehaviour in a Healthy Population.
Paediatric and perinatal epidemiology 2016 Appleton AA, Murphy MA, Koestler DC, Lesseur C, Paquette AG, Padbury JF, Lester BM, Marsit CJ -
Expression and localization of Inter-alpha Inhibitors in rodent brain.
Neuroscience 2016 Chen X, Rivard L, Naqvi S, Nakada S, Padbury JF, Sanchez-Esteban J, Stopa EG, Lim YP, Stonestreet BS -
dbPEC: a comprehensive literature-based database for preeclampsia related genes and phenotypes.
Database : the journal of biological databases and curation 2016 Uzun A, Triche EW, Schuster J, Dewan AT, Padbury JF -
Epigenetic Regulation of Placental NR3C1: Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking?
Child development 2016 Stroud LR, Papandonatos GD, Salisbury AL, Phipps MG, Huestis MA, Niaura R, Padbury JF, Marsit CJ, Lester BM -
Neurobehavior related to epigenetic differences in preterm infants.
Epigenomics 2015 Lester BM, Marsit CJ, Giarraputo J, Hawes K, LaGasse LL, Padbury JF -
Effects of Placental Transfusion on Neonatal and 18 Month Outcomes in Preterm Infants: A Randomized Controlled Trial.
The Journal of pediatrics 2015 Mercer JS, Erickson-Owens DA, Vohr BR, Tucker RJ, Parker AB, Oh W, Padbury JF -
Interleukin-1β transfer across the blood-brain barrier in the ovine fetus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015 Sadowska GB, Chen X, Zhang J, Lim YP, Cummings EE, Makeyev O, Besio WG, Gaitanis J, Padbury JF, Banks WA, Stonestreet BS -
Intranasal versus intraperitoneal delivery of human umbilical cord tissue-derived cultured mesenchymal stromal cells in a murine model of neonatal lung injury.
The American journal of pathology 2014 Liu L, Mao Q, Chu S, Mounayar M, Abdi R, Fodor W, Padbury JF, De Paepe ME -
Single-family room care and neurobehavioral and medical outcomes in preterm infants.
Pediatrics 2014 Lester BM, Hawes K, Abar B, Sullivan M, Miller R, Bigsby R, Laptook A, Salisbury A, Taub M, Lagasse LL, Padbury JF -
Pulmonary hypertension in preterm infants: prevalence and association with bronchopulmonary dysplasia.
The Journal of pediatrics 2014 Mirza H, Ziegler J, Ford S, Padbury J, Tucker R, Laptook A -
Metformin protects cardiomyocyte from doxorubicin induced cytotoxicity through an AMP-activated protein kinase dependent signaling pathway: an in vitro study.
PloS one 2014 Kobashigawa LC, Xu YC, Padbury JF, Tseng YT, Yano N -
Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation.
American journal of obstetrics and gynecology 2014 Lesseur C, Armstrong DA, Paquette AG, Li Z, Padbury JF, Marsit CJ -
Bioinformatic approach to the genetics of preeclampsia.
Obstetrics and gynecology 2014 Triche EW, Uzun A, DeWan AT, Kurihara I, Liu J, Occhiogrosso R, Shen B, Parker J, Padbury JF -
Maternal smoking during pregnancy and infant stress response: test of a prenatal programming hypothesis.
Psychoneuroendocrinology 2014 Stroud LR, Papandonatos GD, Rodriguez D, McCallum M, Salisbury AL, Phipps MG, Lester B, Huestis MA, Niaura R, Padbury JF, Marsit CJ -
HE4 (WFDC2) gene overexpression promotes ovarian tumor growth.
Scientific reports 2014 Moore RG, Hill EK, Horan T, Yano N, Kim K, MacLaughlan S, Lambert-Messerlian G, Tseng YD, Padbury JF, Miller MC, Lange TS, Singh RK -
50 years ago in the Journal of Pediatrics: the behavior of the lower esophageal sphincter in infants and its relationship to gastroesophageal regurgitation.
The Journal of pediatrics 2014 Shah BA, Padbury JF -
Neonatal sepsis: an old problem with new insights.
Virulence 2013 Shah BA, Padbury JF -
PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models.
Genes & cancer 2013 Kawar N, Maclaughlan S, Horan TC, Uzun A, Lange TS, Kim KK, Hopson R, Singh AP, Sidhu PS, Glass KA, Shaw S, Padbury JF, Vorsa N, Arnold LA, Moore RG, Brard L, Singh RK -
Developmental genes targeted for epigenetic variation between twin-twin transfusion syndrome children.
Clinical epigenetics 2013 Marsit CJ, Koestler DC, Watson-Smith D, Boney CM, Padbury JF, Luks F -
Transthyretin is dysregulated in preeclampsia, and its native form prevents the onset of disease in a preclinical mouse model.
The American journal of pathology 2013 Kalkunte SS, Neubeck S, Norris WE, Cheng SB, Kostadinov S, Vu Hoang D, Ahmed A, von Eggeling F, Shaikh Z, Padbury J, Berg G, Olofsson A, Markert UR, Sharma S -
Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity.
PloS one 2013 Appleton AA, Armstrong DA, Lesseur C, Lee J, Padbury JF, Lester BM, Marsit CJ -
Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors.
Molecular and cellular endocrinology 2013 Lesseur C, Armstrong DA, Paquette AG, Koestler DC, Padbury JF, Marsit CJ -
Placental miRNA expression profiles are associated with measures of infant neurobehavioral outcomes.
Pediatric research 2013 Maccani MA, Padbury JF, Lester BM, Knopik VS, Marsit CJ -
Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs.
Respiratory research 2013 Mao Q, Chu S, Ghanta S, Padbury JF, De Paepe ME -
Pregnant and moving: understanding residential mobility during pregnancy and in the first year of life using a prospective birth cohort.
Maternal and child health journal 2013 Saadeh FB, Clark MA, Rogers ML, Linkletter CD, Phipps MG, Padbury JF, Vivier PM -
Long-term outcome of human cord blood-derived hematopoietic progenitor cells in murine lungs.
Experimental lung research 2013 De Paepe ME, Mao Q, Chu S, Padbury JF -
Pathway-based genetic analysis of preterm birth.
Genomics 2013 Uzun A, Dewan AT, Istrail S, Padbury JF -
Behavioral epigenetics and the developmental origins of child mental health disorders.
Journal of developmental origins of health and disease 2012 Lester BM, Marsit CJ, Conradt E, Bromer C, Padbury JF -
In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells.
Cell communication and signaling : CCS 2012 Yano N, Suzuki D, Endoh M, Zhang W, Xu YC, Padbury JF, Tseng YT -
Dynamics of microRNAs in bull spermatozoa.
Reproductive biology and endocrinology : RB&E 2012 Govindaraju A, Uzun A, Robertson L, Atli MO, Kaya A, Topper E, Crate EA, Padbury J, Perkins A, Memili E -
In-vitro validation of cytokine neutralizing antibodies by testing with ovine mononuclear splenocytes.
Journal of comparative pathology 2012 Chen X, Threlkeld SW, Cummings EE, Sadowska GB, Lim YP, Padbury JF, Sharma S, Stonestreet BS -
Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior.
Developmental psychobiology 2012 Bromer C, Marsit CJ, Armstrong DA, Padbury JF, Lester B -
Neonatal intensive care unit: predictive models for length of stay.
Journal of perinatology : official journal of the California Perinatal Association 2012 Bender GJ, Koestler D, Ombao H, McCourt M, Alskinis B, Rubin LP, Padbury JF -
Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model.
PloS one 2012 Moore RG, Lange TS, Robinson K, Kim KK, Uzun A, Horan TC, Kawar N, Yano N, Chu SR, Mao Q, Brard L, DePaepe ME, Padbury JF, Arnold LA, Brodsky A, Shen TL, Singh RK -
Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program.
Transfusion 2012 Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause PJ, Babesia Testing Investigational Containment Study Group -
Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome.
PloS one 2012 Marsit CJ, Maccani MA, Padbury JF, Lester BM -
A bioinformatics approach to preterm birth.
American journal of reproductive immunology (New York, N.Y. : 1989) 2012 Uzun A, Sharma S, Padbury J -
dbPTB: a database for preterm birth.
Database : the journal of biological databases and curation 2012 Uzun A, Laliberte A, Parker J, Andrew C, Winterrowd E, Sharma S, Istrail S, Padbury JF -
Placenta-imprinted gene expression association of infant neurobehavior.
The Journal of pediatrics 2011 Marsit CJ, Lambertini L, Maccani MA, Koestler DC, Houseman EA, Padbury JF, Lester BM, Chen J -
In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta.
Environmental health perspectives 2011 Wilhelm-Benartzi CS, Houseman EA, Maccani MA, Poage GM, Koestler DC, Langevin SM, Gagne LA, Banister CE, Padbury JF, Marsit CJ -
Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas.
Epigenetics 2011 Banister CE, Koestler DC, Maccani MA, Padbury JF, Houseman EA, Marsit CJ -
miR-16 and miR-21 expression in the placenta is associated with fetal growth.
PloS one 2011 Maccani MA, Padbury JF, Marsit CJ -
Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: implications for fetal programming.
Developmental psychobiology 2011 Ponder KL, Salisbury A, McGonnigal B, Laliberte A, Lester B, Padbury JF -
Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells.
The American journal of pathology 2011 De Paepe ME, Mao Q, Ghanta S, Hovanesian V, Padbury JF -
Infant neurobehavioral development.
Seminars in perinatology 2011 Lester BM, Miller RJ, Hawes K, Salisbury A, Bigsby R, Sullivan MC, Padbury JF -
Millennium neonatology: building for the future. Introduction.
Seminars in perinatology 2011 Padbury JF -
Endocrine disruptors, environmental oxygen, epigenetics and pregnancy.
Frontiers in bioscience (Elite edition) 2011 Robins JC, Marsit CJ, Padbury JF, Sharma SS -
Next generation neonatal health informatics with Artemis.
Studies in health technology and informatics 2011 McGregor C, Catley C, James A, Padbury J -
Na+,K+-ATPase activity and subunit protein expression: ontogeny and effects of exogenous and endogenous steroids on the cerebral cortex and renal cortex of sheep.
Reproductive sciences (Thousand Oaks, Calif.) 2010 Kim CR, Sadowska GB, Newton SA, Merino M, Petersson KH, Padbury JF, Stonestreet BS -
Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta.
Epigenetics 2010 Maccani MA, Avissar-Whiting M, Banister CE, McGonnigal B, Padbury JF, Marsit CJ -
Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay.
The American journal of pathology 2010 Kalkunte S, Boij R, Norris W, Friedman J, Lai Z, Kurtis J, Lim KH, Padbury JF, Matthiesen L, Sharma S -
Haplotype-dependent differential activation of the human IL-10 gene promoter in macrophages and trophoblasts: implications for placental IL-10 deficiency and pregnancy complications.
American journal of reproductive immunology (New York, N.Y. : 1989) 2010 Sharma S, Stabila J, Pietras L, Singh AR, McGonnigal B, Ernerudh J, Matthiesen L, Padbury JF -
Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice.
Pediatric research 2010 Singh K, Zhang LX, Bendelja K, Heath R, Murphy S, Sharma S, Padbury JF, Lim YP -
Inter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis.
The Journal of pediatrics 2010 Chaaban H, Shin M, Sirya E, Lim YP, Caplan M, Padbury JF -
Building for the future of Rhode Island's newborns.
Medicine and health, Rhode Island 2010 Padbury JF, VanVleet MW, Lester BM -
Role of the L-amino acid transporter-1 (LAT-1) in mouse trophoblast cell invasion.
Placenta 2010 Chrostowski MK, McGonnigal BG, Stabila JP, Padbury JF -
Effect of disruption of Akt-1 of lin(-)c-kit(+) stem cells on myocardial performance in infarcted heart.
Cardiovascular research 2010 Tseng A, Stabila J, McGonnigal B, Yano N, Yang MJ, Tseng YT, Davol PA, Lum LG, Padbury JF, Zhao TC -
Seven-month developmental outcomes of very low birth weight infants enrolled in a randomized controlled trial of delayed versus immediate cord clamping.
Journal of perinatology : official journal of the California Perinatal Association 2009 Mercer JS, Vohr BR, Erickson-Owens DA, Padbury JF, Oh W -
High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells.
The Biochemical journal 2009 Yano N, Suzuki D, Endoh M, Cao TN, Dahdah JR, Tseng A, Stabila JP, McGonnigal BG, Padbury JF, Tseng YT -
Fetal effects of psychoactive drugs.
Clinics in perinatology 2009 Salisbury AL, Ponder KL, Padbury JF, Lester BM -
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.
PLoS genetics 2009 Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT -
Third pathophysiology of prenatal cocaine exposure.
Developmental neuroscience 2009 Lester BM, Padbury JF -
The role of inter-alpha inhibitor proteins in the diagnosis of neonatal sepsis.
The Journal of pediatrics 2009 Chaaban H, Singh K, Huang J, Siryaporn E, Lim YP, Padbury JF -
LAT-1 expression in pre- and post-implantation embryos and placenta.
Placenta 2009 Chrostowski MK, McGonnigal BG, Stabila JP, Padbury JF -
Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery.
American journal of obstetrics and gynecology 2008 Murphy SP, Hanna NN, Fast LD, Shaw SK, Berg G, Padbury JF, Romero R, Sharma S -
Fate and effects of adult bone marrow cells in lungs of normoxic and hyperoxic newborn mice.
American journal of respiratory cell and molecular biology 2008 Fritzell JA, Mao Q, Gundavarapu S, Pasquariello T, Aliotta JM, Ayala A, Padbury JF, De Paepe ME -
In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts.
Placenta 2008 Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, Sharma S -
Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model.
American journal of physiology. Heart and circulatory physiology 2008 Yano N, Tseng A, Zhao TC, Robbins J, Padbury JF, Tseng YT -
Beta-adrenergic receptor mediated protection against doxorubicin-induced apoptosis in cardiomyocytes: the impact of high ambient glucose.
Endocrinology 2008 Yano N, Suzuki D, Endoh M, Tseng A, Stabila JP, McGonnigal BG, Zhao TC, Padbury JF, Tseng YT -
Increased indomethacin dosing for persistent patent ductus arteriosus in preterm infants: a multicenter, randomized, controlled trial.
The Journal of pediatrics 2008 Jegatheesan P, Ianus V, Buchh B, Yoon G, Chorne N, Ewig A, Lin E, Fields S, Moon-Grady A, Tacy T, Milstein J, Schreiber M, Padbury J, Clyman R -
Forced expression of the cell cycle inhibitor p57Kip2 in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart.
BMC physiology 2008 Haley SA, Zhao T, Zou L, Klysik JE, Padbury JF, Kochilas LK -
Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction.
Journal of applied physiology (Bethesda, Md. : 1985) 2008 Zhao TC, Tseng A, Yano N, Tseng Y, Davol PA, Lee RJ, Lum LG, Padbury JF -
Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury.
Cardiovascular research 2007 Zhao TC, Cheng G, Zhang LX, Tseng YT, Padbury JF -
A novel phosphoinositide 3-kinase-dependent pathway for angiotensin II/AT-1 receptor-mediated induction of collagen synthesis in MES-13 mesangial cells.
The Journal of biological chemistry 2007 Yano N, Suzuki D, Endoh M, Zhao TC, Padbury JF, Tseng YT -
Embryo-placento-maternal interaction and biomarkers: from diagnosis to therapy--a workshop report.
Placenta 2007 Than NG, Paidas MJ, Mizutani S, Sharma S, Padbury J, Barnea ER -
A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2007 Yano N, Ianus V, Zhao TC, Tseng A, Padbury JF, Tseng YT -
Antibody targeting of stem cells to infarcted myocardium.
Stem cells (Dayton, Ohio) 2006 Lee RJ, Fang Q, Davol PA, Gu Y, Sievers RE, Grabert RC, Gall JM, Tsang E, Yee MS, Fok H, Huang NF, Padbury JF, Larrick JW, Lum LG -
Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trial.
Pediatrics 2006 Mercer JS, Vohr BR, McGrath MM, Padbury JF, Wallach M, Oh W -
Effects of postnatal steroids on Na+/K+-ATPase activity and alpha1- and beta1-subunit protein expression in the cerebral cortex and renal cortex of newborn lambs.
Reproduction, fertility, and development 2006 Kim CR, Sadowska GB, Petersson KH, Merino M, Sysyn GD, Padbury JF, Stonestreet BS -
Virtual reality of stem cell transplantation to repair injured myocardium.
Journal of cellular biochemistry 2005 Lum LG, Padbury JF, Davol PA, Lee RJ -
Ontogeny of phosphoinositide 3-kinase signaling in developing heart: effect of acute beta-adrenergic stimulation.
American journal of physiology. Heart and circulatory physiology 2005 Tseng YT, Yano N, Rojan A, Stabila JP, McGonnigal BG, Ianus V, Wadhawan R, Padbury JF -
Ontogeny and the effects of corticosteroid pretreatment on aquaporin water channels in the ovine cerebral cortex.
Reproduction, fertility, and development 2005 Ron NP, Kazianis JA, Padbury JF, Brown CM, McGonnigal BG, Sysyn GD, Sadowska GB, Stonestreet BS -
Transcriptional regulation of the LAT-1/CD98 light chain.
Biochemical and biophysical research communications 2004 Padbury JF, Diah SK, McGonnigal B, Miller C, Fugere C, Kuzniar M, Thompson NL -
Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.
The Journal of biological chemistry 2004 Hleb M, Murphy S, Wagner EF, Hanna NN, Sharma N, Park J, Li XC, Strom TB, Padbury JF, Tseng YT, Sharma S -
A revised allele frequency estimate and haplotype analysis of the DBH deficiency mutation IVS1+2T --> C in African- and European-Americans.
American journal of medical genetics. Part A 2003 Zabetian CP, Romero R, Robertson D, Sharma S, Padbury JF, Kuivaniemi H, Kim KS, Kim CH, Köhnke MD, Kranzler HR, Gelernter J, Cubells JF -
Inter-alpha inhibitor proteins in infants and decreased levels in neonatal sepsis.
The Journal of pediatrics 2003 Baek YW, Brokat S, Padbury JF, Pinar H, Hixson DC, Lim YP -
Regulation of cardiac beta 1-adrenergic receptor transcription during the developmental transition.
American journal of physiology. Heart and circulatory physiology 2003 Wadhawan R, Tseng YT, Stabila J, McGonnigal B, Sarkar S, Padbury J -
Molecular interactions between glucocorticoid and catecholamine signaling pathways.
The Journal of allergy and clinical immunology 2002 Tseng YT, Wadhawan R, Stabila JP, McGonnigal BG, Padbury JF -
1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxy vitamin D3: production and biological activity studies in pulmonary alveolar type II cells.
Molecular genetics and metabolism 2002 Rehan VK, Torday JS, Peleg S, Gennaro L, Vouros P, Padbury J, Rao DS, Reddy GS -
Newborn screening: an overview with an update on recent advances.
Current problems in pediatric and adolescent health care 2002 Goodwin G, Msall ME, Vohr BR, Rubin LP, Padbury J -
Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by catecholamines via alpha-adrenergic signaling.
American journal of physiology. Regulatory, integrative and comparative physiology 2001 Sarkar S, Tsai SW, Nguyen TT, Plevyak M, Padbury JF, Rubin LP -
Liganded and unliganded steroid receptor modulation of beta 1 adrenergic receptor gene transcription.
Pediatric research 2001 McNab TC, Tseng YT, Stabila JP, McGonnigal BG, Padbury JF -
Beta-adrenergic receptors (betaAR) regulate cardiomyocyte proliferation during early postnatal life.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001 Tseng YT, Kopel R, Stabila JP, McGonnigal BG, Nguyen TT, Gruppuso PA, Padbury JF -
A novel glucocorticoid regulatory unit mediates the hormone responsiveness of the beta1-adrenergic receptor gene.
Molecular and cellular endocrinology 2001 Tseng YT, Stabila JP, Nguyen TT, McGonnigal BG, Waschek JA, Padbury JF -
The interactive effects of endotoxin with prenatal glucocorticoids on short-term lung function in sheep.
American journal of obstetrics and gynecology 2001 Newnham JP, Moss TJ, Padbury JF, Willet KE, Ikegami M, Ervin MG, Sly P, Jobe A -
Molecular cloning of the rat TA1/LAT-1/CD98 light chain gene promoter.
Biochimica et biophysica acta 2001 Diah SK, Padbury JF, Campbell WA, Britt D, Thompson NL -
The effect of maternal hypoaminoacidaemia on placental uptake and transport of amino acids in pregnant sheep.
Placenta 2001 Thureen PJ, Padbury JF, Hay WW -
The use of inhaled glucocorticosteroids and recovery from adrenal suppression after systemic steroid use in a VLBW premature infant with BPD: case report and literature discussion.
Neonatal network : NN 2000 Karinski DA, Balkundi D, Rubin LP, Padbury JF -
Cloning and sequence analysis of the rat norepinephrine transporter promoter.
Brain research. Molecular brain research 2000 Padbury JF, McGonnigal B, Tseng YT, Nguyen TT, Stabila JP -
Endotoxin-induced lung maturation in preterm lambs is not mediated by cortisol.
American journal of respiratory and critical care medicine 2000 Jobe AH, Newnham JP, Willet KE, Moss TJ, Gore Ervin M, Padbury JF, Sly P, Ikegami M -
Antenatal glucocorticoids alter premature newborn lamb neuroendocrine and endocrine responses to hypoxia.
American journal of physiology. Regulatory, integrative and comparative physiology 2000 Ervin MG, Padbury JF, Polk DH, Ikegami M, Berry LM, Jobe AH -
Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts.
Journal of immunology (Baltimore, Md. : 1950) 2000 Hanna N, Hanna I, Hleb M, Wagner E, Dougherty J, Balkundi D, Padbury J, Sharma S -
Primer extension methods for determination of beta 1-adrenergic receptor mRNA start sites.
Methods in molecular biology (Clifton, N.J.) 2000 Tseng YT, Padbury JF -
Transient transfection and adrenergic receptor promoter analysis.
Methods in molecular biology (Clifton, N.J.) 2000 Tseng YT, Padbury JF -
Placental biogenic amine transporters: in vivo function, regulation and pathobiological significance.
Placenta 1999 Nguyen TT, Tseng YT, McGonnigal B, Stabila JP, Worrell LA, Saha S, Padbury JF -
An inverted cAMP response element mediates the cAMP induction of the ovine beta 1-adrenergic receptor gene.
Biochemistry and molecular biology international 1998 Tseng YT, Stabila J, McGonnigal B, Nguyen TT, Padbury JF -
Neonatal dopamine pharmacodynamics: lessons from the bedside.
The Journal of pediatrics 1998 Padbury JF -
Premature "closing" of the foramen ovale in transposition of the great arteries with intact ventricular septum: rare cause of sudden neonatal death.
Pediatric cardiology 1998 Berry LM, Padbury J, Novoa-Takara L, Emmanouilides GC -
Antenatal thyrotropin-releasing hormone to prevent lung disease in preterm infants. North American Thyrotropin-Releasing Hormone Study Group.
The New England journal of medicine 1998 Ballard RA, Ballard PL, Cnaan A, Pinto-Martin J, Davis DJ, Padbury JF, Phibbs RH, Parer JT, Hart MC, Mannino FL, Sawai SK -
Expression of a pulmonary endothelial norepinephrine transporter.
Journal of neural transmission (Vienna, Austria : 1996) 1998 Tseng YT, Padbury JF -
Sulfoconjugation and renal excretion contribute to the interpatient variation of exogenous catecholamine clearance in critically ill children.
Critical care medicine 1997 Berg RA, Padbury JF -
Preterm newborn lamb renal and cardiovascular responses after fetal or maternal antenatal betamethasone.
The American journal of physiology 1997 Berry LM, Polk DH, Ikegami M, Jobe AH, Padbury JF, Ervin MG -
Laryngotracheal stenosis in a case of Pena-Shokier syndrome.
American journal of otolaryngology 1997 Billings KR, Kerner MM, Padbury JF, Abemayor E -
Placental biogenic amine transporters: cloning and expression.
Brain research. Molecular brain research 1997 Padbury JF, Tseng YT, McGonnigal B, Penado K, Stephan M, Rudnick G -
Human placental norepinephrine transporter mRNA: expression and correlation with fetal condition at birth.
Placenta 1997 Bzoskie L, Yen J, Tseng YT, Blount L, Kashiwai K, Padbury JF -
A comparative study of cardiovascular, endocrine and behavioural effects of betamethasone and dexamethasone administration to fetal sheep.
The Journal of physiology 1997 Derks JB, Giussani DA, Jenkins SL, Wentworth RA, Visser GH, Padbury JF, Nathanielsz PW -
Combined effects of fetal beta agonist stimulation and glucocorticoids on lung function of preterm lambs.
Biology of the neonate 1997 Jobe AH, Ikegami M, Padbury J, Polk DH, Korirnilli A, Gonzales LW, Ballard PL -
Placental norepinephrine transporter development in the ovine fetus.
Placenta 1997 Bzoskie I, Blount I, Kashiwai K, Humme J, Padbury JF -
The contribution of transporter-dependent uptake to fetal catecholamine clearance.
Biology of the neonate 1997 Bzoskie L, Blount L, Kashiwai K, Humme J, Padbury JF -
Lung CuZn-superoxide dismutase and catalase gene expression in premature rabbits treated intratracheally with antioxidant-surfactant liposomes.
Biochemical and molecular medicine 1996 Walther FJ, Mehta EI, Padbury JF -
Single dose fetal betamethasone administration stabilizes postnatal glomerular filtration rate and alters endocrine function in premature lambs.
Pediatric research 1996 Ervin MG, Berry LM, Ikegami M, Jobe AH, Padbury JF, Polk DH -
Preterm betamethasone treatment of fetal sheep: outcome after term delivery.
Journal of the Society for Gynecologic Investigation 1996 Jobe AH, Polk DH, Ervin MG, Padbury JF, Rebello CM, Ikegami M -
Ovine fetal-placental cocaine pharmacokinetics during continuous cocaine infusion.
Journal of the Society for Gynecologic Investigation 1996 Downs T, Padbury J, Blount L, Kashiwai K, Chan K -
Extrapulmonary effects of antenatally administered steroids.
The Journal of pediatrics 1996 Padbury JF, Ervin MG, Polk DH -
Postnatal cardiovascular and metabolic responses to a single intramuscular dose of betamethasone in fetal sheep born prematurely by cesarean section.
Pediatric research 1995 Padbury JF, Polk DH, Ervin MG, Berry LM, Ikegami M, Jobe AH -
Functional analysis of the 5' flanking sequence in the ovine beta 1-adrenergic receptor gene.
Biochemical and biophysical research communications 1995 Tseng YT, Waschek JA, Padbury JF -
Placental norepinephrine clearance: in vivo measurement and physiological role.
The American journal of physiology 1995 Bzoskie L, Blount L, Kashiwai K, Tseng YT, Hay WW, Padbury JF -
Transcription initiation is localized to a TATAless region in the ovine beta 1 adrenergic receptor gene.
Biochemical and biophysical research communications 1995 Padbury JF, Tseng YT, Waschek JA -
Regulation of beta 1-adrenoceptors by glucocorticoids and thyroid hormones in fetal sheep.
European journal of pharmacology 1995 Tseng YT, Tucker MA, Kashiwai KT, Waschek JA, Padbury JF -
A cloning strategy for G-protein-coupled hormone receptors: the ovine beta 1-adrenergic receptor.
Reproduction, fertility, and development 1995 Padbury JF, Tseng YT, Waschek JA -
Effect of corticosteroids on free and sulfoconjugated catecholamines at birth in premature newborn sheep.
The American journal of physiology 1995 Stein HM, Martinez A, Oyama K, Blount L, Padbury JF -
Hemodynamic adaptations at birth and neonates delivered vaginally and by Cesarean section.
Biology of the neonate 1995 Agata Y, Hiraishi S, Misawa H, Han JH, Oguchi K, Horiguchi Y, Fujino N, Takeda N, Padbury JF -
Catecholamine response to ultrasonographically guided percutaneous blood sampling in fetal sheep.
American journal of obstetrics and gynecology 1994 Newnham JP, Polk DH, Kelly RW, Padbury JF, Evans SF, Ikegami M, Jobe AH -
The effects of corticosteroids and thyrotropin-releasing hormone on newborn adaptation and sympathoadrenal mechanisms in preterm sheep.
American journal of obstetrics and gynecology 1994 Stein HM, Martinez A, Blount L, Oyama K, Padbury JF -
Fetal endocrine and renal responses to in utero ventilation and umbilical cord occlusion.
American journal of obstetrics and gynecology 1993 Ogundipe OA, Kullama LK, Stein H, Nijland MJ, Ervin MG, Padbury J, Ross MG -
Plasma epinephrine appearance and clearance rates in fetal and newborn sheep.
The American journal of physiology 1993 Stein H, Oyama K, Martinez A, Chappell B, Padbury J -
Dobutamine pharmacokinetics and pharmacodynamics in normal children and adolescents.
The Journal of pharmacology and experimental therapeutics 1993 Berg RA, Padbury JF, Donnerstein RL, Klewer SE, Hutter JJ -
Dobutamine infusions in stable, critically ill children: pharmacokinetics and hemodynamic actions.
Critical care medicine 1993 Berg RA, Donnerstein RL, Padbury JF -
Effects of corticosteroids in preterm sheep on adaptation and sympathoadrenal mechanisms at birth.
The American journal of physiology 1993 Stein HM, Oyama K, Martinez A, Chappell BA, Buhl E, Blount L, Padbury JF -
Fetal catecholamine, cardiovascular, and neurobehavioral responses to cocaine.
American journal of obstetrics and gynecology 1992 Chan K, Dodd PA, Day L, Kullama L, Ervin MG, Padbury J, Ross MG -
Plasma thyroid hormones and prolactin in premature infants and their mothers after prenatal treatment with thyrotropin-releasing hormone.
Pediatric research 1992 Ballard PL, Ballard RA, Creasy RK, Padbury J, Polk DH, Bracken M, Moya FR, Gross I -
Effects of fetal growth retardation on the development of central and peripheral catecholaminergic pathways in the sheep.
Journal of developmental physiology 1992 Oyama K, Padbury J, Martinez A, Chappell B, Stein H, Humme J -
Single umbilical artery ligation-induced fetal growth retardation: effect on postnatal adaptation.
The American journal of physiology 1992 Oyama K, Padbury J, Chappell B, Martinez A, Stein H, Humme J -
Effects of acute oligohydramnios on respiratory system of fetal sheep.
Journal of applied physiology (Bethesda, Md. : 1985) 1992 Savich RD, Guerra FA, Lee CC, Padbury JF, Kitterman JA -
Intraosseous versus intravenous epinephrine infusions in lambs: pharmacokinetics and pharmacodynamics.
Pediatric emergency care 1992 Sapien R, Stein H, Padbury JF, Thio S, Hodge D -
Free and sulfoconjugated catecholamine responses at birth in newborn sheep.
The American journal of physiology 1992 Oyama K, Padbury J, Martinez A, Chappell B, Stein H, Blount L, Buhl E -
Dobutamine pharmacokinetics and pharmacodynamics in pediatric intensive care patients.
Critical care medicine 1992 Habib DM, Padbury JF, Anas NG, Perkin RM, Minegar C -
Elevated plasma Met-enkephalin levels in the human newborn are a poor indicator of perinatal stress.
American journal of obstetrics and gynecology 1992 Martinez AM, Padbury JF, Barberie LM, Burnell EE, Thio S -
Prolonged beta-agonist infusion does not induce desensitization or down-regulation of beta-adrenergic receptors in newborn sheep.
Pediatric research 1992 Stein HM, Oyama K, Sapien R, Chappell BA, Padbury JF -
Respiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid. TRH Study Group.
Lancet (London, England) 1992 Ballard RA, Ballard PL, Creasy RK, Padbury J, Polk DH, Bracken M, Moya FR, Gross I -
Dobutamine pharmacokinetics and cardiovascular responses in critically ill neonates.
Pediatrics 1992 Martinez AM, Padbury JF, Thio S -
A controlled trial of insulin infusion and parenteral nutrition in extremely low birth weight infants with glucose intolerance.
The Journal of pediatrics 1991 Collins JW, Hoppe M, Brown K, Edidin DV, Padbury J, Ogata ES -
Maturational changes in expression of enkephalin peptides in adrenal and extra-adrenal tissue of fetal and adult rabbits.
Brain research bulletin 1991 Martinez A, Padbury J, Chappell B, Habib D, Thio S, Burnell E -
Cardiovascular effects of SKF 104078 in lambs.
Developmental pharmacology and therapeutics 1991 Chappell B, Padbury J, Martinez A, Habib D, Stein H, Oyama K -
Neonatal adaptation: cardiac adrenergic effector mechanisms after birth in newborn sheep.
Pediatric research 1991 Habib DM, Padbury JF, Martinez AM, Chappell BA, Thio SL, Burnell EE -
Ovine fetal renal and hormonal responses to changes in plasma epinephrine.
The American journal of physiology 1991 Ervin MG, Castro R, Sherman DJ, Ross MG, Padbury JF, Leake RD, Fisher DA -
Plasma methionine enkephalin levels in the human newborn at birth.
Biology of the neonate 1991 Martinez AM, Padbury JF, Burnell EE, Thio SL -
Pulmonary clearance of norepinephrine in lambs.
Pediatric research 1991 Chappell BA, Padbury JF, Habib DM, Martinez AM, Thio SL, Burnell EE, Humme JA -
Fetal catecholamine responses to maternal hypoglycemia.
The American journal of physiology 1990 Harwell CM, Padbury JF, Anand RS, Martinez AM, Ipp E, Thio SL, Burnell EE -
Pharmacokinetics of dopamine in critically ill newborn infants.
The Journal of pediatrics 1990 Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Habib DM, Martinez AM -
Plasma catecholamines and their physiologic thresholds during the first ten days of life in sheep.
Journal of developmental physiology 1990 Martinez AM, Padbury JF, Humme JA, Evans CW, Shames L -
The effects of hypoxia on (methionine) enkephalin peptide and catecholamine release in fetal sheep.
Pediatric research 1990 Martinez AM, Padbury JF, Burnell EE, Thio SL, Humme J -
Functional maturation of the adrenal medulla and peripheral sympathetic nervous system.
Bailliere's clinical endocrinology and metabolism 1989 Padbury JF -
Hemodynamic and neuroendocrine adaptations of the preterm lamb left ventricle to acutely increased afterload.
Pediatric research 1989 Baylen BG, Agata Y, Padbury JF, Ikegami M, Jobe AH, Emmanouilides GC -
Free and sulfoconjugated catecholamine responses to hypoxia in fetal sheep.
The American journal of physiology 1989 Padbury JF, Martinez AM, Thio SL, Burnell EE, Humme JA -
Developmental changes in adrenergic regulation of fetal arginine vasopressin secretion.
The American journal of physiology 1989 Ervin MG, Padbury JF, Ross MG, Leake RD, Fisher DA -
Thresholds for the physiologic effects of adrenergic agents: a methodologic appraisal.
Developmental pharmacology and therapeutics 1989 Padbury JF, Habib DM, Martinez AM -
Naloxone potentiates epinephrine release during hypoxia in fetal sheep: dose response and cardiovascular effects.
Pediatric research 1988 Martinez A, Padbury J, Shames L, Evans C, Humme J -
Sympathoadrenal system activity at birth: integration of postnatal adaptation.
Seminars in perinatology 1988 Padbury JF, Martinez AM -
The role of beta-adrenoreceptor stimulation and contractile state in the preterm lamb's response to altered ductus arteriosus patency.
Pediatric research 1988 Clyman RI, Teitel D, Padbury J, Roman C, Mauray F -
Catecholamine and endorphin responses to delivery in term and preterm lambs.
Developmental pharmacology and therapeutics 1988 Padbury JF, Agata Y, Polk DH, Wang DL, Lam RW, Callegari CC -
Effect of fetal adrenalectomy on catecholamine release and physiologic adaptation at birth in sheep.
The Journal of clinical investigation 1987 Padbury J, Agata Y, Ludlow J, Ikegami M, Baylen B, Humme J -
Neonatal adaptation: naloxone increases the catecholamine surge at birth.
Pediatric research 1987 Padbury JF, Agata Y, Polk DH, Wang DL, Callegari CC -
Effect of fetal thyroidectomy on newborn thermogenesis in lambs.
Pediatric research 1987 Polk DH, Callegari CC, Newnham J, Padbury JF, Reviczky A, Fisher DA, Klein AH -
Thresholds for physiological effects of plasma catecholamines in fetal sheep.
The American journal of physiology 1987 Padbury JF, Ludlow JK, Ervin MG, Jacobs HC, Humme JA -
Epidermal growth factor acts as a corticotropin-releasing factor in chronically catheterized fetal lambs.
The Journal of clinical investigation 1987 Polk DH, Ervin MG, Padbury JF, Lam RW, Reviczky AL, Fisher DA -
Dopamine pharmacokinetics in critically ill newborn infants.
The Journal of pediatrics 1987 Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Goldblatt E, Pescetti J -
The effect of chemical sympathectomy on catecholamine release at birth.
Pediatric research 1986 Agata Y, Padbury JF, Ludlow JK, Polk DH, Humme JA -
Autoimmune sympathectomy in fetal rabbits.
Journal of developmental physiology 1986 Padbury JF, Lam RW, Polk DH, Newnham JP, Lakshmanan J, Fisher DA -
Metabolic clearance and plasma appearance rates of catecholamines in preterm and term fetal sheep.
Pediatric research 1986 Padbury JF, Ludlow JK, Humme JA, Agata Y -
Effects of amiodarone and desethylamiodarone on rabbit myocardial beta-adrenoceptors and serum thyroid hormones--absence of relationship to serum and myocardial drug concentrations.
Journal of cardiovascular pharmacology 1986 Venkatesh N, Padbury JF, Singh BN -
Involvement of developing sympathetic nervous system in thyroxine-mediated submandibular gland nerve growth factor and epidermal growth factor responses.
Pediatric research 1986 Lakshmanan J, Padbury J, Macaso T, Wang D, Beri U, Fisher DA -
Differential response of ovine placental lactogen levels in maternal and fetal circulations following single umbilical artery ligation in fetal sheep.
Placenta 1986 Newnham JP, Lam RW, Hobel CJ, Padbury JF, Polk DH, Fisher DA -
Effect of thyroid status on lung and heart beta-adrenergic receptors in fetal and newborn sheep.
Developmental pharmacology and therapeutics 1986 Padbury JF, Klein AH, Polk DH, Lam RW, Hobel C, Fisher DA -
Neonatal adaptation: greater sympathoadrenal response in preterm than full-term fetal sheep at birth.
The American journal of physiology 1985 Padbury JF, Polk DH, Newnham JP, Lam RW -
Fetal catecholamine release with preterm delivery.
American journal of obstetrics and gynecology 1984 Newnham JP, Marshall CL, Padbury JF, Lam RW, Hobel CJ, Fisher DA -
Thyroid hormones augment catecholamine-stimulated brown adipose tissue thermogenesis in the ovine fetus.
Endocrinology 1984 Klein AH, Reviczky A, Padbury JF -
[Adrenal epinephrine and the regulation of pulmonary surfactant release in neonatal rabbits].
Experimental lung research 1984 Padbury JF, Jacobs HC, Lam RW, Conaway D, Jobe AH, Fisher DA -
Effect of changes in thyroid status on tissue respiration in fetal and newborn sheep.
The American journal of physiology 1983 Klein AH, Reviczky A, Padbury JF, Fisher DA -
Development of brown adipose tissue thermogenesis in the ovine fetus and newborn.
Endocrinology 1983 Klein AH, Reviczky A, Chou P, Padbury J, Fisher DA -
Identification and partial purification of phenylethanolamine N-methyl transferase in the developing ovine lung.
Pediatric research 1983 Padbury JF, Lam RW, Hobel CJ, Fisher DA -
Saturated phosphatidylcholine secretion and the effect of natural surfactant on premature and term lambs ventilated for 2 days.
Experimental lung research 1983 Jobe A, Ikegami M, Glatz T, Yoshida Y, Diakomanolis E, Padbury J -
Ontogenesis and sex differences in rabbit fetal adrenal phenylethanolamine N-methyltransferase.
Biology of the neonate 1983 Padbury JF, Hobel CJ, Gonzalez FA, Fisher DA -
Fetal catecholamine release in response to labor and delivery.
Obstetrics and gynecology 1982 Padbury JF, Roberman B, Oddie TH, Hobel CJ, Fisher DA -
Neonatal adaptation: sympatho-adrenal response to umbilical cord cutting.
Pediatric research 1981 Padbury JF, Diakomanolis ES, Hobel CJ, Perelman A, Fisher DA -
Ontogenesis of tissue catecholamines in fetal and neonatal rabbits.
Journal of developmental physiology 1981 Padbury JF, Diakomanolis ES, Lam RW, Hobel CJ, Fisher DA -
Sex differences in lung and adrenal neurosympathetic development in rabbits.
American journal of obstetrics and gynecology 1981 Padbury JF, Hobel CJ, Lam RW, Fisher DA -
Ontogenesis of beta-adrenergic receptors in the ovine placenta.
American journal of obstetrics and gynecology 1981 Padbury JF, Hobel CJ, Diakomanolis ES, Lam RW, Fisher DA -
Duration and characteristics of treatment of premature lambs with natural surfactant.
The Journal of clinical investigation 1981 Jobe A, Ikegami M, Glatz T, Yoshida Y, Diakomanolis E, Padbury J