Jill Hollenbach, PhD, MPH
Professor
Neurology
School of Medicine

Our work spans the population genetics, evolutionary history, and influence on human health of these complex genomic regions, with particular emphasis on their role in neurological disease.

• High-throughput complement component 4 genomic sequence analysis with C4Investigator.
  bioRxiv : the preprint server for biology 2023 Marin WM, Augusto DG, Wade KJ, Hollenbach JA
• Genotype List String 1.1: Extending the Genotype List String grammar for describing HLA and Killer-cell Immunoglobulin-like Receptor genotypes.
  HLA 2023 Mack SJ, Schefzyk D, Millius RP, Maiers M, Hollenbach JA, Pollack J, Heuer ML, Gragert L, Spellman SR, Guethlein LA, Schneider J, Bochtler W, Eberhard HP, Robinson J, Marsh SGE, Schmidt AH, Hofmann JA…
• A Predictive Autoantibody Signature in Multiple Sclerosis.
  medRxiv : the preprint server for health sciences 2023 Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Tubati A, Gomez R, Fouassier C, Gerungan C, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, …
• Adeno-associated virus 2 infection in children with non-A-E hepatitis.
  Nature 2023 Ho A, Orton R, Tayler R, Asamaphan P, Herder V, Davis C, Tong L, Smollett K, Manali M, Allan J, Rawlik K, McDonald SE, Vink E, Pollock L, Gannon L, Evans C, McMenamin J, Roy K, Marsh K, Divala T, …
• Software update: Interpreting killer-cell immunoglobulin-like receptors from whole genome sequence data with PING.
  HLA 2023 Marin WM, Hollenbach JA
• The immunogenetics of COVID-19.
  Immunogenetics 2022 Srivastava A, Hollenbach JA
• A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.
  medRxiv : the preprint server for health sciences 2022 Augusto DG, Yusufali T, Sabatino JJ, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, …
• Interaction between maternal killer immunoglobulin-like receptors and offspring HLAs and susceptibility of childhood ALL.
  Blood advances 2022 Feng Q, Zhou M, Li S, Morimoto L, Hansen H, Myint SS, Wang R, Metayer C, Kang A, Fear AL, Pappas D, Erlich H, Hollenbach JA, Mancuso N, Trachtenberg E, de Smith AJ, Ma X, Wiemels JL
• HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection.
  Current opinion in immunology 2022 Augusto DG, Hollenbach JA
• A short HLA-DRA isoform binds the HLA-DR2 heterodimer on the outer domain of the peptide-binding site.
  Archives of biochemistry and biophysics 2022 Shams H, Hollenbach JA, Matsunaga A, Mofrad MRK, Oksenberg JR, Didonna A
• Minimal observed impact of HLA genotype on hospitalization and severity of SARS-CoV-2 infection.
  HLA 2022 Nguyen A, Yusufali T, Hollenbach JA, Nellore A, Thompson RF
• Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine-induced antibody and T cell immunity and function.
  JCI insight 2022 Sabatino JJ, Mittl K, Rowles WM, McPolin K, Rajan JV, Laurie MT, Zamecnik CR, Dandekar R, Alvarenga BD, Loudermilk RP, Gerungan C, Spencer CM, Sagan SA, Augusto DG, Alexander JR, DeRisi JL, Hollenbach…
• Remarkably Low KIR and HLA Diversity in Amerindians Reveals Signatures of Strong Purifying Selection Shaping the Centromeric KIR Region.
  Molecular biology and evolution 2022 Vargas LB, Beltrame MH, Ho B, Marin WM, Dandekar R, Montero-Martín G, Fernández-Viña MA, Hurtado AM, Hill KR, Tsuneto LT, Hutz MH, Salzano FM, Petzl-Erler ML, Hollenbach JA, Augusto DG
• HLA-A Locus is Associated With Sepsis and Septic Shock After Traumatic Injury.
  Annals of surgery 2022 Horn DL, Mindrinos M, Anderson K, Krishnakumar S, Wang C, Li M, Hollenbach J, O'Keefe GE
• Approaching Genetics Through the MHC Lens: Tools and Methods for HLA Research.
  Frontiers in genetics 2021 Douillard V, Castelli EC, Mack SJ, Hollenbach JA, Gourraud PA, Vince N, Limou S
• Current HLA Investigations on SARS-CoV-2 and Perspectives.
  Frontiers in genetics 2021 Douillard V, Castelli EC, Mack SJ, Hollenbach JA, Gourraud PA, Vince N, Limou S, Covid-19|HLA & Immunogenetics Consortium and the SNP-HLA Reference Consortium
• Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles.
  Annals of the rheumatic diseases 2021 Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu C, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Rosa …
• Analysis of Genomic DNA from Medieval Plague Victims Suggests Long-Term Effect of Yersinia pestis on Human Immunity Genes.
  Molecular biology and evolution 2021 Immel A, Key FM, Szolek A, Barquera R, Robinson MK, Harrison GF, Palmer WH, Spyrou MA, Susat J, Krause-Kyora B, Bos KI, Forrest S, Hernández-Zaragoza DI, Sauter J, Solloch U, Schmidt AH, Schuenemann …
• An immunogenetic view of COVID-19.
  Genetics and molecular biology 2021 Aguiar VRC, Augusto DG, Castelli EC, Hollenbach JA, Meyer D, Nunes K, Petzl-Erler ML
• Identifying falls remotely in people with multiple sclerosis.
  Journal of neurology 2021 Block VJ, Pitsch EA, Gopal A, Zhao C, Pletcher MJ, Marcus GM, Olgin JE, Hollenbach J, Bove R, Cree BAC, Gelfand JM
• High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING.
  PLoS computational biology 2021 Marin WM, Dandekar R, Augusto DG, Yusufali T, Heyn B, Hofmann J, Lange V, Sauter J, Norman PJ, Hollenbach JA
• Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01.
  Journal of immunology (Baltimore, Md. : 1950) 2021 Guethlein LA, Beyzaie N, Nemat-Gorgani N, Wang T, Ramesh V, Marin WM, Hollenbach JA, Schetelig J, Spellman SR, Marsh SGE, Cooley S, Weisdorf DJ, Norman PJ, Miller JS, Parham P
• Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.
  Frontiers in immunology 2021 Ahn R, Vukcevic D, Motyer A, Nititham J, Squire DM, Hollenbach JA, Norman PJ, Ellinghaus E, Nair RP, Tsoi LC, Oksenberg J, Foerster J, Lieb W, Weidinger S, Franke A, Elder JT, Jorgenson E, Leslie S, …
• Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations.
  Frontiers in immunology 2021 Creary LE, Gangavarapu S, Caillier SJ, Cavalcante P, Frangiamore R, Lie BA, Bengtsson M, Harbo HF, Brauner S, Hollenbach JA, Oksenberg JR, Bernasconi P, Maniaol AH, Hammarström L, Mantegazza R, …
• Measuring Race and Ancestry in the Age of Genetic Testing.
  Demography 2021 Johfre SS, Saperstein A, Hollenbach JA
• High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility.
  Frontiers in immunology 2021 Osoegawa K, Creary LE, Montero-Martín G, Mallempati KC, Gangavarapu S, Caillier SJ, Santaniello A, Isobe N, Hollenbach JA, Hauser SL, Oksenberg JR, Fernández-Vina MA
• High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity.
  Frontiers in immunology 2021 Amorim LM, Augusto DG, Nemat-Gorgani N, Montero-Martin G, Marin WM, Shams H, Dandekar R, Caillier S, Parham P, Fernández-Viña MA, Oksenberg JR, Norman PJ, Hollenbach JA
• Behçet disease, new insights in disease associations and manifestations: a next-generation sequencing study.
  Clinical and experimental immunology 2021 Elfishawi M, Mossallam G, Augusto DG, Montero-Martin G, de Bruin H, Van de Pasch L, Norman PJ, Rozemuller E, Fernandez-Vina M, Abrudescu A, Hollenbach JA, Zaky K, Elfishawi S
• A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain.
  Immunology 2020 Didonna A, Damotte V, Shams H, Matsunaga A, Caillier SJ, Dandekar R, Misra MK, Mofrad MRK, Oksenberg JR, Hollenbach JA
• Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations.
  Frontiers in immunology 2020 Vargas LB, Dourado RM, Amorim LM, Ho B, Calonga-Solís V, Issler HC, Marin WM, Beltrame MH, Petzl-Erler ML, Hollenbach JA, Augusto DG
• Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease.
  Journal of immunology (Baltimore, Md. : 1950) 2020 Anderson KM, Augusto DG, Dandekar R, Shams H, Zhao C, Yusufali T, Montero-Martín G, Marin WM, Nemat-Gorgani N, Creary LE, Caillier S, Mofrad MRK, Parham P, Fernández-Viña M, Oksenberg JR, Norman PJ, …
• KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors.
  Frontiers in immunology 2020 Alicata C, Ashouri E, Nemat-Gorgani N, Guethlein LA, Marin WM, Tao S, Moretta L, Hollenbach JA, Trowsdale J, Traherne JA, Ghaderi A, Parham P, Norman PJ
• Validation of a consumer-grade activity monitor for continuous daily activity monitoring in individuals with multiple sclerosis.
  Multiple sclerosis journal - experimental, translational and clinical 2019 Block VJ, Zhao C, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Henry R, Gelfand JM, Cree BA
• Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years.
  JAMA neurology 2019 Cantó E, Barro C, Zhao C, Caillier SJ, Michalak Z, Bove R, Tomic D, Santaniello A, Häring DA, Hollenbach J, Henry RG, Cree BAC, Kappos L, Leppert D, Hauser SL, Benkert P, Oksenberg JR, Kuhle J
• Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population.
  Human immunology 2019 Creary LE, Gangavarapu S, Mallempati KC, Montero-Martín G, Caillier SJ, Santaniello A, Hollenbach JA, Oksenberg JR, Fernández-Viña MA
• Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region.
  Frontiers in immunology 2019 Augusto DG, Norman PJ, Dandekar R, Hollenbach JA
• Silent progression in disease activity-free relapsing multiple sclerosis.
  Annals of neurology 2019 University of California, San Francisco MS-EPIC Team, Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS,…
• A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, …
• Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis.
  JAMA network open 2019 Block VJ, Bove R, Zhao C, Garcha P, Graves J, Romeo AR, Green AJ, Allen DD, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Cree BAC, Gelfand JM
• Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates.
  Frontiers in immunology 2019 Leaton LA, Shortt J, Kichula KM, Tao S, Nemat-Gorgani N, Mentzer AJ, Oppenheimer SJ, Deng Z, Hollenbach JA, Gignoux CR, Guethlein LA, Parham P, Carrington M, Norman PJ
• Consumer (dis-)interest in Genetic Ancestry Testing: The roles of race, immigration, and ancestral certainty.
  New genetics and society 2019 Horowitz AL, Saperstein A, Little J, Maiers M, Hollenbach JA
• Allele-Level KIR Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations.
  Frontiers in immunology 2018 Wagner I, Schefzyk D, Pruschke J, Schöfl G, Schöne B, Gruber N, Lang K, Hofmann J, Gnahm C, Heyn B, Marin WM, Dandekar R, Hollenbach JA, Schetelig J, Pingel J, Norman PJ, Sauter J, Schmidt AH, Lange V
• Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis.
  HLA 2018 Amorim LM, Santos THS, Hollenbach JA, Norman PJ, Marin WM, Dandekar R, Ribeiro EMSF, Petzl-Erler ML, Augusto DG
• Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.
  Human immunology 2018 Misra MK, Augusto DG, Martin GM, Nemat-Gorgani N, Sauter J, Hofmann JA, Traherne JA, González-Quezada B, Gorodezky C, Bultitude WP, Marin W, Vierra-Green C, Anderson KM, Balas A, Caro-Oleas JL, …
• Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis.
  Genes and immunity 2018 Misra MK, Damotte V, Hollenbach JA
• Harnessing electronic medical records to advance research on multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2018 Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, …
• The immunogenetics of neurological disease.
  Immunology 2017 Misra MK, Damotte V, Hollenbach JA
• Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.
  The pharmacogenomics journal 2017 Pappas DJ, Lizee A, Paunic V, Beutner KR, Motyer A, Vukcevic D, Leslie S, Biesiada J, Meller J, Taylor KD, Zheng X, Zhao LP, Gourraud PA, Hollenbach JA, Mack SJ, Maiers M
• Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
  Genome research 2017 Norman PJ, Norberg SJ, Guethlein LA, Nemat-Gorgani N, Royce T, Wroblewski EE, Dunn T, Mann T, Alicata C, Hollenbach JA, Chang W, Shults Won M, Gunderson KL, Abi-Rached L, Ronaghi M, Parham P
• Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.
  PLoS medicine 2017 Steele NZ, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS
• Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.
  American journal of human genetics 2016 Norman PJ, Hollenbach JA, Nemat-Gorgani N, Marin WM, Norberg SJ, Ashouri E, Jayaraman J, Wroblewski EE, Trowsdale J, Rajalingam R, Oksenberg JR, Chiaroni J, Guethlein LA, Traherne JA, Ronaghi M, …
• Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis.
  JAMA neurology 2016 Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG
• Multidimensional reduction of multicentric cohort heterogeneity: An alternative method to increase statistical power and robustness.
  Human immunology 2016 Le Gall C, Laurent J, Vince N, Lizee A, Agrawal A, Walencik A, Rettman P, Gagne K, Retiere C, Hollenbach J, Cesbron A, Limou S, Gourraud PA
• The killer immunoglobulin-like receptor KIR3DL1 in combination with HLA-Bw4 is protective against multiple sclerosis in African Americans.
  Genes and immunity 2016 Hollenbach JA, Pando MJ, Caillier SJ, Gourraud PA, Oksenberg JR
• Molecular Pathology in Clinical Practice
  Molecular HLA Typing 2016 Malek Kamoun, Jill A Hollenbach, Steven J Mack, Thomas M Williams
• Bridging ImmunoGenomic Data Analysis Workflow Gaps (BIGDAWG): An integrated case-control analysis pipeline.
  Human immunology 2015 Pappas DJ, Marin W, Hollenbach JA, Mack SJ
• The GL service: Web service to exchange GL string encoded HLA & KIR genotypes with complete and accurate allele and genotype ambiguity.
  Human immunology 2015 Milius RP, Heuer M, George M, Pollack J, Hollenbach JA, Mack SJ, Maiers M
• KIR haplotypes are associated with late-onset type 1 diabetes in European-American families.
  Genes and immunity 2015 Traherne JA, Jiang W, Valdes AM, Hollenbach JA, Jayaraman J, Lane JA, Johnson C, Trowsdale J, Noble JA
• Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.
  Human immunology 2015 Mack SJ, Milius RP, Gifford BD, Sauter J, Hofmann J, Osoegawa K, Robinson J, Groeneweg M, Turenchalk GS, Adai A, Holcomb C, Rozemuller EH, Penning MT, Heuer ML, Wang C, Salit ML, Schmidt AH, Parham PR…
• Histoimmunogenetics Markup Language 1.0: Reporting next generation sequencing-based HLA and KIR genotyping.
  Human immunology 2015 Milius RP, Heuer M, Valiga D, Doroschak KJ, Kennedy CJ, Bolon YT, Schneider J, Pollack J, Kim HR, Cereb N, Hollenbach JA, Mack SJ, Maiers M
• Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.
  PLoS genetics 2015 Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P
• Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.
  PloS one 2015 Hollenbach JA, Saperstein A, Albrecht M, Vierra-Green C, Parham P, Norman PJ, Maiers M
• Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines.
  Immunogenetics 2015 Norman PJ, Norberg SJ, Nemat-Gorgani N, Royce T, Hollenbach JA, Shults Won M, Guethlein LA, Gunderson KL, Ronaghi M, Parham P
• The immunogenetics of multiple sclerosis: A comprehensive review.
  Journal of autoimmunity 2015 Hollenbach JA, Oksenberg JR
• HLA class II genotypes are not associated with age related macular degeneration in a case-control, population-based study.
  Human immunology 2015 Pappas D, Hollenbach J, Coleman AL, Gorin MB, Yu F, Williams K, Noble J, Tranah GJ, Study of Osteoporotic Fractures (SOF) Research Group
• A deep look at KIR-HLA in Amerindians: comprehensive meta-analysis reveals limited diversity of KIR haplotypes.
  Human immunology 2015 Augusto DG, Hollenbach JA, Petzl-Erler ML
• KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.
  Immunogenetics 2014 Nemat-Gorgani N, Edinur HA, Hollenbach JA, Traherne JA, Dunn PP, Chambers GK, Parham P, Norman PJ
• Validation of statistical imputation of allele-level multilocus phased genotypes from ambiguous HLA assignments.
  Tissue antigens 2014 Madbouly A, Gragert L, Freeman J, Leahy N, Gourraud PA, Hollenbach JA, Kamoun M, Fernandez-Vina M, Maiers M
• Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.
  PLoS genetics 2013 Norman PJ, Hollenbach JA, Nemat-Gorgani N, Guethlein LA, Hilton HG, Pando MJ, Koram KA, Riley EM, Abi-Rached L, Parham P
• Genotype List String: a grammar for describing HLA and KIR genotyping results in a text string.
  Tissue antigens 2013 Milius RP, Mack SJ, Hollenbach JA, Pollack J, Heuer ML, Gragert L, Spellman S, Guethlein LA, Trachtenberg EA, Cooley S, Bochtler W, Mueller CR, Robinson J, Marsh SG, Maiers M
• Common and well-documented HLA alleles: 2012 update to the CWD catalogue.
  Tissue antigens 2013 Mack SJ, Cano P, Hollenbach JA, He J, Hurley CK, Middleton D, Moraes ME, Pereira SE, Kempenich JH, Reed EF, Setterholm M, Smith AG, Tilanus MG, Torres M, Varney MD, Voorter CE, Fischer GF, …
• 16(th) IHIW: immunogenomic data-management methods. report from the immunogenomic data analysis working group (IDAWG).
  International journal of immunogenetics 2012 Hollenbach JA, Holcomb C, Hurley CK, Mabdouly A, Maiers M, Noble JA, Robinson J, Schmidt AH, Shi L, Turner V, Yao Y, Mack SJ
• 16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands.
  International journal of immunogenetics 2012 Hollenbach JA, Augusto DG, Alaez C, Bubnova L, Fae I, Fischer G, Gonzalez-Galarza FF, Gorodezky C, Karabon L, Kusnierczyk P, Noble J, Rickards O, Roberts C, Schaffer M, Shi L, Tavoularis S, …
• 16(th) IHIW: extending the number of resources and bioinformatics analysis for the investigation of HLA rare alleles.
  International journal of immunogenetics 2012 Gonzalez-Galarza FF, Mack SJ, Hollenbach J, Fernandez-Vina M, Setterholm M, Kempenich J, Marsh SG, Jones AR, Middleton D, HLA Rare Allele Consortium
• Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals.
  PloS one 2012 Vierra-Green C, Roe D, Hou L, Hurley CK, Rajalingam R, Reed E, Lebedeva T, Yu N, Stewart M, Noreen H, Hollenbach JA, Guethlein LA, Wang T, Spellman S, Maiers M
• Killer cell immunoglobulin-like receptor (KIR) gene content variation in the HGDP-CEPH populations.
  Immunogenetics 2012 Hollenbach JA, Nocedal I, Ladner MB, Single RM, Trachtenberg EA
• A combined DPA1~DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer.
  Immunogenetics 2012 Hollenbach JA, Madbouly A, Gragert L, Vierra-Green C, Flesch S, Spellman S, Begovich A, Noreen H, Trachtenberg E, Williams T, Yu N, Shaw B, Fleischhauer K, Fernandez-Vina M, Maiers M
• Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2012 Fernandez Vina MA, Hollenbach JA, Lyke KE, Sztein MB, Maiers M, Klitz W, Cano P, Mack S, Single R, Brautbar C, Israel S, Raimondi E, Khoriaty E, Inati A, Andreani M, Testi M, Moraes ME, Thomson G, …
• Analytical methods for disease association studies with immunogenetic data.
  Methods in molecular biology (Clifton, N.J.) 2012 Hollenbach JA, Mack SJ, Thomson G, Gourraud PA
• Analytical methods for immunogenetic population data.
  Methods in molecular biology (Clifton, N.J.) 2012 Mack SJ, Gourraud PA, Single RM, Thomson G, Hollenbach JA
• Standard methods for the management of immunogenetic data.
  Methods in molecular biology (Clifton, N.J.) 2012 Gourraud PA, Hollenbach JA, Barnetche T, Single RM, Mack SJ
• A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement.
  Tissue antigens 2011 Hollenbach JA, Mack SJ, Gourraud PA, Single RM, Maiers M, Middleton D, Thomson G, Marsh SG, Varney MD, Immunogenomics Data Analysis Working Group
• Immunogenetics as a tool in anthropological studies.
  Immunology 2011 Sanchez-Mazas A, Fernandez-Viña M, Middleton D, Hollenbach JA, Buhler S, Di D, Rajalingam R, Dugoujon JM, Mack SJ, Thorsby E
• Association of HLA alleles with Plasmodium falciparum severity in Malian children.
  Tissue antigens 2011 Lyke KE, Fernández-Vina MA, Cao K, Hollenbach J, Coulibaly D, Kone AK, Guindo A, Burdett LA, Hartzman RJ, Wahl AR, Hildebrand WH, Doumbo OK, Plowe CV, Sztein MB
• Juvenile idiopathic arthritis and HLA class I and class II interactions and age-at-onset effects.
  Arthritis and rheumatism 2010 Hollenbach JA, Thompson SD, Bugawan TL, Ryan M, Sudman M, Marion M, Langefeld CD, Thomson G, Erlich HA, Glass DN
• Allele Name Translation Tool and Update NomenCLature: software tools for the automated translation of HLA allele names between successive nomenclatures.
  Tissue antigens 2010 Mack SJ, Hollenbach JA
• Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.
  Tissue antigens 2010 Hollenbach JA, Meenagh A, Sleator C, Alaez C, Bengoche M, Canossi A, Contreras G, Creary L, Evseeva I, Gorodezky C, Hardie RA, Karlsen TH, Lie B, Luo M, Martinetti M, Navarette C, de Oliveira DC, …
• Sequence feature variant type (SFVT) analysis of the HLA genetic association in juvenile idiopathic arthritis.
  Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2010 Thomson G, Marthandan N, Hollenbach JA, Mack SJ, Erlich HA, Single RM, Waller MJ, Marsh SG, Guidry PA, Karp DR, Scheuermann RH, Thompson SD, Glass DN, Helmberg W
• Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand.
  Immunogenetics 2009 Hollenbach JA, Ladner MB, Saeteurn K, Taylor KD, Mei L, Haritunians T, McGovern DP, Erlich HA, Rotter JI, Trachtenberg EA
• HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.
  Tissue antigens 2007 Trachtenberg E, Vinson M, Hayes E, Hsu YM, Houtchens K, Erlich H, Klitz W, Hsia Y, Hollenbach J
• Haplotype frequency estimation in patient populations: the effect of departures from Hardy-Weinberg proportions and collapsing over a locus in the HLA region.
  Genetic epidemiology 2002 Single RM, Meyer D, Hollenbach JA, Nelson MP, Noble JA, Erlich HA, Thomson G
• Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations.
  Human immunology 2001 Cao K, Hollenbach J, Shi X, Shi W, Chopek M, Fernández-Viña MA
• Genetic variability and linkage disequilibrium within the HLA-DP region: analysis of 15 different populations.
  Tissue antigens 2001 Begovich AB, Moonsamy PV, Mack SJ, Barcellos LF, Steiner LL, Grams S, Suraj-Baker V, Hollenbach J, Trachtenberg E, Louie L, Zimmerman P, Hill AV, Stoneking M, Sasazuki T, Konenkov VI, Sartakova ML, …
• HLA diversity, differentiation, and haplotype evolution in Mesoamerican Natives.
  Human immunology 2001 Hollenbach JA, Thomson G, Cao K, Fernandez-Vina M, Erlich HA, Bugawan TL, Winkler C, Winter M, Klitz W
• Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, and DPB1) loci in 26 human ethnic groups.
  Tissue antigens 1999 Chen JJ, Hollenbach JA, Trachtenberg EA, Just JJ, Carrington M, Rønningen KS, Begovich A, King MC, McWeeney S, Mack SJ, Erlich HA, Thomson G