Jie Liu, PhD, MS
Postdoctoral Scholar
Cellular Molecular Pharmacology
School of Medicine

Publications (11)

Top publication keywords:
Cycloaddition ReactionStereoisomerismOsteoblastsAlkaloidsQuinolinesBiological ProductsMonoterpenesEvolution, ChemicalPyrrolidinesOxidoreductases Acting on CH-CH Group DonorsPrincipal Component AnalysisSesterterpenesSesquiterpenesMolecular StructureIndole Alkaloids

• A divergent intermediate strategy yields biologically diverse pseudo-natural products.
  Nature chemistry 2024 Bag S, Liu J, Patil S, Bonowski J, Koska S, Schölermann B, Zhang R, Wang L, Pahl A, Sievers S, Brieger L, Strohmann C, Ziegler S, Grigalunas M, Waldmann H
• Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.
  Chemistry (Weinheim an der Bergstrasse, Germany) 2023 Aoyama H, Davies C, Liu J, Pahl A, Kirchhoff JL, Scheel R, Sievers S, Strohmann C, Grigalunas M, Waldmann H
• Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.
  Angewandte Chemie (International ed. in English) 2023 Xie J, Pahl A, Krzyzanowski A, Krupp A, Liu J, Koska S, Schölermann B, Zhang R, Bonowski J, Sievers S, Strohmann C, Ziegler S, Grigalunas M, Waldmann H
• A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway.
  Chemical science 2023 Liu J, Zhang R, Mallick S, Patil S, Wientjens C, Flegel J, Krupp A, Strohmann C, Grassin C, Merten C, Pahl A, Grigalunas M, Waldmann H
• Morphological Profiling Identifies the Motor Protein Eg5 as Cellular Target of Spirooxindoles.
  Angewandte Chemie (International ed. in English) 2023 Liu J, Mallick S, Xie Y, Grassin C, Lucas B, Schölermann B, Pahl A, Scheel R, Strohmann C, Protzel C, Berg T, Merten C, Ziegler S, Waldmann H

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• Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay.
  Chembiochem : a European journal of chemical biology 2022 Schölermann B, Bonowski J, Grigalunas M, Burhop A, Xie Y, Hoock JGF, Liu J, Dow M, Nelson A, Nowak C, Pahl A, Sievers S, Ziegler S
• Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids.
  Angewandte Chemie (International ed. in English) 2021 Liu J, Flegel J, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H
• Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products.
  Angewandte Chemie (International ed. in English) 2021 Liu J, Cremosnik GS, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H
• Guided by evolution: from biology oriented synthesis to pseudo natural products.
  Natural product reports 2020 Cremosnik GS, Liu J, Waldmann H
• A Unified Approach for the Assembly of Atisine- and Hetidine-type Diterpenoid Alkaloids: Total Syntheses of Azitine and the Proposed Structure of Navirine C.
  Angewandte Chemie (International ed. in English) 2018 Liu J, Ma D
• Total synthesis of leucosceptroids A and B.
  Angewandte Chemie (International ed. in English) 2014 Guo S, Liu J, Ma D