Jia Yang, PhD
Assistant Researcher
Bioengineering
School of Pharmacy

Publications (38)

Top publication keywords:
Antineoplastic Agents, ImmunologicalDendritic CellsReceptors, GABAPancreatic NeoplasmsImmunotherapy, AdoptiveCD8-Positive T-LymphocytesDiabetes Insipidus, NephrogenicCarcinoma, Pancreatic DuctalAblation TechniquesCancer VaccinesElectroporationLiver NeoplasmsAquaporin 2Purkinje CellsATPases Associated with Diverse Cellular Activities

• Membrane transporters in drug development and as determinants of precision medicine.
  Nature reviews. Drug discovery 2024 Galetin A, Brouwer KLR, Tweedie D, Yoshida K, Sjöstedt N, Aleksunes L, Chu X, Evers R, Hafey MJ, Lai Y, Matsson P, Riselli A, Shen H, Sparreboom A, Varma MVS, Yang J, Yang X, Yee SW, Zamek-…
• Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior.
  Cells 2023 Li C, Zhang H, Tong K, Cai M, Gao F, Yang J, Xu Y, Wang H, Chen H, Hu Y, He W, Zhang J
• ATPase Thorase Deficiency Causes α-synucleinopathy and Parkinson’s Disease-Like Behavior by Impairing PINK1/Parkin-Mediated Mitophagy
  Cells 2022 Gao F, Zhang H, Yang J, Cai H, Yang Q, Wang H, Xu Y, Chen H, Hu Y, He W, and Zhang J
• Early Differentiation of Irreversible Electroporation Ablation Regions With Radiomics Features of Conventional MRI.
  Academic radiology 2021 Eresen A, Sun C, Zhou K, Shangguan J, Wang B, Pan L, Hu S, Ma Q, Yang J, Zhang Z, Yaghmai V
• Molecular Characterization of an Aquaporin-2 Mutation Causing Nephrogenic Diabetes Insipidus.
  Frontiers in endocrinology 2021 Li Q, Lu B, Yang J, Li C, Li Y, Chen H, Li N, Duan L, Gu F, Zhang J, Xia W

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• TSPO deficiency accelerates amyloid pathology and neuroinflammation by impairing microglial phagocytosis.
  Neurobiology of aging 2021 Zhang H, Wang H, Gao F, Yang J, Xu Y, Fu Y, Cai M, Zhang X, Yang Q, Tong K, Hu Y, Chen H, Ma C, He W, Zhang J
• Combination of natural killer cell-based immunotherapy and irreversible electroporation for the treatment of hepatocellular carcinoma.
  Annals of translational medicine 2021 Eresen A, Yang J, Scotti A, Cai K, Yaghmai V, Zhang Z
• Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer.
  Oncoimmunology 2021 Yang J, Eresen A, Shangguan J, Ma Q, Yaghmai V, Zhang Z
• Combination of NK-based immunotherapy and sorafenib against hepatocellular carcinoma.
  American journal of cancer research 2021 Yang J, Eresen A, Scotti A, Cai K, Zhang Z
• Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation.
  Communications biology 2020 Yao Y, Yang J, Qin Q, Tang C, Li Z, Chen L, Li K, Ren C, Chen L, Rao S
• Intraprocedural Transcatheter Intraarterial Perfusion (TRIP)-MRI for Evaluation of Irreversible Electroporation Therapy Response in a Rabbit Liver Tumor Model.
  Clinical and experimental gastroenterology 2020 Shangguan AJ, Zhou K, Yang J, Eresen A, Wang B, Sun C, Pan L, Hu S, Khan AT, Mouli SK, Yaghmai V, Zhang Z
• Effect of route of administration on the efficacy of dendritic cell vaccine in PDAC mice.
  American journal of cancer research 2020 Yang J, Eresen A, Shangguan J, Ma Q, Zhang Z, Yaghmai V
• Preoperative prediction of perineural invasion and KRAS mutation in colon cancer using machine learning.
  Journal of cancer research and clinical oncology 2020 Li Y, Eresen A, Shangguan J, Yang J, Benson AB, Yaghmai V, Zhang Z
• Detection of Immunotherapeutic Response in a Transgenic Mouse Model of Pancreatic Ductal Adenocarcinoma Using Multiparametric MRI Radiomics: A Preliminary Investigation.
  Academic radiology 2020 Eresen A, Yang J, Shangguan J, Benson AB, Yaghmai V, Zhang Z
• Prediction of therapeutic outcome and survival in a transgenic mouse model of pancreatic ductal adenocarcinoma treated with dendritic cell vaccination or CDK inhibitor using MRI texture: a feasibility study.
  American journal of translational research 2020 Eresen A, Yang J, Shangguan J, Li Y, Hu S, Sun C, Yaghmai V, Benson Iii AB, Zhang Z
• Preoperative assessment of lymph node metastasis in Colon Cancer patients using machine learning: a pilot study.
  Cancer imaging : the official publication of the International Cancer Imaging Society 2020 Eresen A, Li Y, Yang J, Shangguan J, Velichko Y, Yaghmai V, Benson AB, Zhang Z
• No Evidence for Widespread Positive Selection Signatures in Common Risk Alleles Associated with Schizophrenia.
  Schizophrenia bulletin 2020 Yao Y, Yang J, Xie Y, Liao H, Yang B, Xu Q, Rao S
• Dinaciclib prolongs survival in the LSL-KrasG12D/+ ; LSL-Trp53R172H/+ ; Pdx-1-Cre (KPC) transgenic murine models of pancreatic ductal adenocarcinoma.
  American journal of translational research 2020 Yang J, Hu S, Shangguan J, Eresen A, Li Y, Ma Q, Yaghmai V, Benson Iii AB, Zhang Z
• MRI radiomics for early prediction of response to vaccine therapy in a transgenic mouse model of pancreatic ductal adenocarcinoma.
  Journal of translational medicine 2020 Eresen A, Yang J, Shangguan J, Li Y, Hu S, Sun C, Velichko Y, Yaghmai V, Benson AB, Zhang Z
• Transcatheter Intraarterial Perfusion MRI Approaches to Differentiate Reversibly Electroporated Penumbra From Irreversibly Electroporated Zones in Rabbit Liver.
  Academic radiology 2020 Pan L, Sun C, Zhou K, Figini M, Wang B, Shangguan J, Hu S, Yang J, Xing W, Wang J, Velichko Y, Yaghmai V, Zhang Z
• Contrast-enhanced CT radiomics for predicting lymph node metastasis in pancreatic ductal adenocarcinoma: a pilot study.
  Cancer imaging : the official publication of the International Cancer Imaging Society 2020 Li K, Yao Q, Xiao J, Li M, Yang J, Hou W, Du M, Chen K, Qu Y, Li L, Li J, Wang X, Luo H, Yang J, Zhang Z, Chen W
• Prophylactic dendritic cell vaccination controls pancreatic cancer growth in a mouse model.
  Cytotherapy 2020 Shangguan A, Shang N, Figini M, Pan L, Yang J, Ma Q, Hu S, Eresen A, Sun C, Wang B, Velichko Y, Yaghmai V, Zhang Z
• Transcatheter intra-arterial perfusion (TRIP)-MRI biomarkers help detect immediate response to irreversible electroporation of rabbit VX2 liver tumor.
  Magnetic resonance in medicine 2019 Figini M, Zhou K, Pan L, Sun C, Wang B, Hu S, Yang J, Shangguan J, Eresen A, Velichko Y, Yaghmai V, Zhang Z
• Dendritic cell immunotherapy induces anti-tumor effect in a transgenic mouse model of pancreatic ductal adenocarcinoma.
  American journal of cancer research 2019 Yang J, Hu S, Shangguan J, Eresen A, Li Y, Pan L, Ma Q, Velichko Y, Wang J, Hu C, Yaghmai V, Zhang Z
• Establishment of a new non-invasive imaging prediction model for liver metastasis in colon cancer.
  American journal of cancer research 2019 Li Y, Eresen A, Shangguan J, Yang J, Lu Y, Chen D, Wang J, Velichko Y, Yaghmai V, Zhang Z
• Dendritic cells in pancreatic cancer immunotherapy: Vaccines and combination immunotherapies.
  Pathology, research and practice 2019 Yang J, Shangguan J, Eresen A, Li Y, Wang J, Zhang Z
• Diffusion-Weighted MR Imaging to Evaluate Immediate Response to Irreversible Electroporation in a Rabbit VX2 Liver Tumor Model.
  Journal of vascular and interventional radiology : JVIR 2019 Hu S, Sun C, Wang B, Zhou K, Pan L, Shangguan J, Yang J, Yaghmai V, Figini M, Zhang Z
• DWI and DCE-MRI approaches for differentiating reversibly electroporated penumbra from irreversibly electroporated ablation zones in a rabbit liver model.
  American journal of cancer research 2019 Shangguan AJ, Sun C, Wang B, Pan L, Ma Q, Hu S, Yang J, Eresen A, Velichko Y, Yaghmai V, Zhang Z
• Natural killer cell-based adoptive transfer immunotherapy for pancreatic ductal adenocarcinoma in a KrasLSL-G12Dp53LSL-R172HPdx1-Cre mouse model.
  American journal of cancer research 2019 Hu S, Yang J, Shangguan J, Eresen A, Li Y, Ma Q, Yaghmai V, Velichko Y, Hu C, Zhang Z
• Radiomics signature for the preoperative assessment of stage in advanced colon cancer.
  American journal of cancer research 2019 Li Y, Eresen A, Lu Y, Yang J, Shangguan J, Velichko Y, Yaghmai V, Zhang Z
• Magnetic resonance imaging monitoring therapeutic response to dendritic cell vaccine in murine orthotopic pancreatic cancer models.
  American journal of cancer research 2019 Pan L, Shang N, Shangguan J, Figini M, Xing W, Wang B, Sun C, Yang J, Zhang Y, Hu S, Ma Q, Wang J, Velichko Y, Yaghmai V, Benson AB, Zhang Z
• MRI Assessment of Associations between Brown Adipose Tissue and Cachexia in Murine Pancreatic Ductal Adenocarcinoma.
  Internal medicine: open access 2019 Zhang Y, Hu S, Shangguan J, Pan L, Zhou X, Yaghmai V, Velichko Y, Hu C, Yang J, Zhang Z
• Non-invasive Imaging Methods for Brown Adipose Tissue Detection and Function Evaluation.
  Internal medicine: open access 2019 Zhang Y, Hu X, Hu S, Scotti A, Cai K, Wang J, Zhou X, Yang D, Figini M, Pan L, Shangguan J, Yang J, Zhang Z
• Non-invasive dynamic monitoring initiation and growth of pancreatic tumor in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model.
  Journal of immunological methods 2018 Hu S, Pan L, Shangguan J, Figini M, Eresen A, Sun C, Wang B, Ma Q, Hu C, Yaghmai V, Velichko Y, Yang J, Zhang Z
• The AAA + ATPase Thorase is neuroprotective against ischemic injury.
  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2018 Zhang J, Yang J, Wang H, Sherbini O, Keuss MJ, Umanah GK, Pai EL, Chi Z, Paldanius KM, He W, Wang H, Andrabi SA, Dawson TM, Dawson VL
• Mitophagy in Parkinson's Disease: Pathogenic and Therapeutic Implications.
  Frontiers in neurology 2017 Gao F, Yang J, Wang D, Li C, Fu Y, Wang H, He W, Zhang J
• Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile.
  PloS one 2016 Wang H, Zhai K, Xue Y, Yang J, Yang Q, Fu Y, Hu Y, Liu F, Wang W, Cui L, Chen H, Zhang J, He W
• High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death.
  eNeuro 2016 Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, Dawson TM, Dawson VL