Jhoanne Bautista, MD, PhD
Resident Physician
Surgery
School of Medicine

Publications (16)

Top publication keywords:
Genetic HeterogeneitySingle-Cell AnalysisMesodermEpithelial CellsSelf TolerancePericytesPancreatic ElastaseThymus GlandReceptors, Antigen, T-CellGene Expression ProfilingGenetic Diseases, InbornT-Lymphocytes, RegulatoryAutoimmunityGenes, T-Cell Receptor betaThymocytes

• Single-cell multiomics defines tolerogenic extrathymic Aire-expressing cells with unique homology to thymic epithelium.
  The Journal of Immunology 2022 Jiaxi Wang, Caleb A Lareau, Jhoanne L Bautista, Im Hong Sun, Alexander R Gupta, James M Gardner
• Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.
  Science immunology 2021 Wang J, Lareau CA, Bautista JL, Gupta AR, Sandor K, Germino J, Yin Y, Arvedson MP, Reeder GC, Cramer NT, Xie F, Ntranos V, Satpathy AT, Anderson MS, Gardner JM
• Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla.
  Nature communications 2021 Bautista JL, Cramer NT, Miller CN, Chavez J, Berrios DI, Byrnes LE, Germino J, Ntranos V, Sneddon JB, Burt TD, Gardner JM, Ye CJ, Anderson MS, Parent AV
• Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
  The Journal of clinical investigation 2019 Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA
• Aire deficiency during early pregnancy leads to maternal T cell imbalance and embryo loss.
  The Journal of Immunology 2019 Eva Mae Gillis-Buck, James M. Gardner, Jhoanne L. Bautista, Mark S. Anderson, Adrian Erlebacher, Tippi C. MacKenzie

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• Autoimmune regulator gene supports maternal-fetal immune tolerance during early pregnancy.
  The Journal of Immunology 2018 Eva Mae Gillis-Buck, Jhoanne L. Bautista, Mark S. Anderson, Tippi C. MacKenzie
• A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.
  Immunity 2012 Lee HM, Bautista JL, Scott-Browne J, Mohan JF, Hsieh CS
• Responsiveness to IL-2 characterizes a stable Foxp3+ subset in mice (148.16).
  The Journal of Immunology 2011 Jhoanne Bautista, Susan Gilfillan, Marco Colonna, Chyi-Song Hsieh
• Thymic and peripheral differentiation of regulatory T cells.
  Advances in immunology 2011 Lee HM, Bautista JL, Hsieh CS
• Sliding set-points of immune responses for therapy of autoimmunity.
  The Journal of experimental medicine 2010 Hsieh CS, Bautista JL
• Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
  Journal of immunology (Baltimore, Md. : 1950) 2010 Lu SX, Holland AM, Na IK, Terwey TH, Alpdogan O, Bautista JL, Smith OM, Suh D, King C, Kochman A, Hubbard VM, Rao UK, Yim N, Liu C, Laga AC, Murphy G, Jenq RR, Zakrzewski JL, Penack O, Dykstra L, …
• P-Selectin Regulates Leukocyte Trafficking And Experimental Graft-Versus-Host-Disease After Allogeneic Bone Marrow Transplantation.
  Biology of Blood and Marrow Transplantation 2010 S.X. Lu, M.L. Palomba, I.-K. Na, T.H. Terwey, O. Alpdogan, J.L. Bautista, M. Smith, D. Suh, C.G. King, U.K. Rao, N. Yim, R.R. Jenq, J.L. Zakrzewski, A.M. Holland, O. Penack, L. Dykstra, K. Bampoe, M.R…
• Intraclonal competition limits the fate determination of regulatory T cells in the thymus.
  Nature immunology 2009 Bautista JL, Lio CW, Lathrop SK, Forbush K, Liang Y, Luo J, Rudensky AY, Hsieh CS
• SY-24 Thymic and peripheral regulatory T-cell development.
  Cytokine 2008 Chyi-Song Hsieh, Chan Wang Lio, Stephanie K. Lathrop, Jhoanne Bautista, Hyang Mi Lee, Nicole San
• An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells.
  The Journal of experimental medicine 2007 Graham DB, Stephenson LM, Lam SK, Brim K, Lee HM, Bautista J, Gilfillan S, Akilesh S, Fujikawa K, Swat W
• Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.
  The Journal of clinical investigation 2007 Graham DB, Robertson CM, Bautista J, Mascarenhas F, Diacovo MJ, Montgrain V, Lam SK, Cremasco V, Dunne WM, Faccio R, Coopersmith CM, Swat W