Jessica Sheu-Gruttadauria, PhD
Postdoctoral Scholar
Cellular Molecular Pharmacology
School of Medicine

Publications (12)

Top publication keywords:
RNA InterferenceArgonaute ProteinsFluorescence Recovery After PhotobleachingRNA-Binding ProteinsSpodopteraRNA StabilityRNA, MessengerEukaryotic CellsNucleic Acid ConformationBinding SitesRNA-Induced Silencing ComplexHEK293 CellsMicroRNAsPhase TransitionSf9 Cells

• Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress.
  bioRxiv : the preprint server for biology 2024 Liboy-Lugo JM, Espinoza CA, Sheu-Gruttadauria J, Park JE, Xu A, Jowhar Z, Gao AL, Carmona-Negrón JA, Wittmann T, Jura N, Floor SN
• Nucleolar dynamics are determined by the ordered assembly of the ribosome.
  bioRxiv : the preprint server for biology 2023 Sheu-Gruttadauria J, Yan X, Stuurman N, Floor SN, Vale RD
• How Complementary Targets Expose the microRNA 3' End for Tailing and Trimming during Target-Directed microRNA Degradation.
  Cold Spring Harbor symposia on quantitative biology 2020 Pawlica P, Sheu-Gruttadauria J, MacRae IJ, Steitz JA
• Structural Basis for Target-Directed MicroRNA Degradation.
  Molecular cell 2019 Sheu-Gruttadauria J, Pawlica P, Klum SM, Wang S, Yario TA, Schirle Oakdale NT, Steitz JA, MacRae IJ
• Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
  The EMBO journal 2019 Sheu-Gruttadauria J, Xiao Y, Gebert LF, MacRae IJ

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• COMRADES determines in vivo RNA structures and interactions.
  Nature methods 2018 Ziv O, Gabryelska MM, Lun ATL, Gebert LFR, Sheu-Gruttadauria J, Meredith LW, Liu ZY, Kwok CK, Qin CF, MacRae IJ, Goodfellow I, Marioni JC, Kudla G, Miska EA
• Phase Transitions in the Assembly and Function of Human miRISC.
  Cell 2018 Sheu-Gruttadauria J, MacRae IJ
• Structural Foundations of RNA Silencing by Argonaute.
  Journal of molecular biology 2017 Sheu-Gruttadauria J, MacRae IJ
• Structure-Guided Control of siRNA Off-Target Effects.
  Journal of the American Chemical Society 2016 Suter SR, Sheu-Gruttadauria J, Schirle NT, Valenzuela R, Ball-Jones AA, Onizuka K, MacRae IJ, Beal PA
• Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
  eLife 2015 Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo C, MacRae IJ
• Structural basis for microRNA targeting.
  Science (New York, N.Y.) 2014 Schirle NT, Sheu-Gruttadauria J, MacRae IJ
• Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway.
  The Journal of biological chemistry 2012 Kang H, Louie J, Weisman A, Sheu-Gruttadauria J, Davis-Dusenbery BN, Lagna G, Hata A