Jessica Shantha, MD, MS
Associate Professor
Proctor Foundation
Chancellor/EVC/FAS

In research, Shantha's interests include eye inflammation and emerging pathogens (agents that cause disease). She is also interested in addressing international gaps in care and research for eye diseases. She worked in West Africa for two years treating patients who had eye conditions and were living in limited-resource settings. She continues to advocate for Ebola virus survivors who need ongoing eye care and is dedicated to working toward equity in vision health.

Shantha completed her medical degree at the Morehouse School of Medicine and completed a residency in ophthalmology at Emory University. She completed a fellowship in medical retinal disease at Retina Consultants of Hawaii and a fellowship in clinical uveitis at the UCSF Francis I. Proctor Foundation for Research in Ophthalmology.

• Visual acuity and vision-related quality of life outcomes following cataract surgery in Ebola virus disease survivors.
  Global journal of cataract surgery and research in ophthalmology 2023 Taraborelli D, Thomas JJ, Kim L, Fashina T, Hayek B, Mattia JG, Vandy M, Sugar E, Crozier I, Yeh S, Shantha JG
• Anxiety and depression in patients with uveitis: a comprehensive review of observational studies.
  Current opinion in ophthalmology 2023 Choo CH, Gonzales J, Shantha JG
• Clinical Characteristics and Aetiology of Uveitis in a Viral Haemorrhagic Fever Zone.
  Research square 2023 Balendra S, Williams L, Mustapha J, Koroma Z, Kamara A, Conteh O, Kanu T, Saradugu B, Kamara S, Ward L, Wang H, Fashina T, Koroma S, Shantha J, Yeh S, Kennedy A
• Isolated Ocular Mpox without Skin Lesions, United States.
  Emerging infectious diseases 2023 Nguyen MT, Mentreddy A, Schallhorn J, Chan M, Aung S, Doernberg SB, Babik J, Miles K, Yang K, Lydon E, Minter DJ, Gonzales J, Shantha J, Doan T, Seitzman GD
• Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.
  Ocular immunology and inflammation 2023 Liao A, Fajoles-Vasseneix C, Rali A, Ward L, Fernandes A, Patel PS, O'Keefe G, Shantha JG, Yeh S
• Therapeutic Drug Monitoring in Noninfectious Uveitis.
  JAMA ophthalmology 2023 Shantha J, Acharya NR
• Global Ophthalmic Health Initiatives in Ebola and Emerging Infectious Disease Outbreaks: Implications for Vision Health Systems, Program Implementation, and Disease Surveillance.
  International ophthalmology clinics 2022 Huang Y, Mustapha J, Harrison-Williams L, Fashina T, Randleman C, Ifantides C, Shantha JG, Yeh S
• Research Partnerships and Guidance in Academic Global Ophthalmology.
  International ophthalmology clinics 2022 Ehrlich JR, Shantha JG, Mathenge C, Fashina T, Cole E, Al-Khaled T, Ravilla T, Chan RVP, Yeh S, American Academy of Ophthalmology Task Force on Academic Global Ophthalmology
• COVID-19 and the eye: Systemic and laboratory risk factors for retinopathy and detection of tear film SARS-CoV-2 RNA with a triplex RT-PCR assay.
  PloS one 2022 Shantha JG, Fashina T, Stittleburg V, Randleman C, Ward L, Regueiro M, Krakow D, Linderman SL, Drews-Botsch C, Ahmed R, Waggoner J, Yeh S
• Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey.
  Communications biology 2022 Worwa G, Cooper TK, Yeh S, Shantha JG, Hischak AMW, Klim SE, Byrum R, Kurtz JR, Anthony SM, Aiosa NM, Ragland D, Lee JH, Claire MS, Davis C, Ahmed R, Holbrook MR, Kuhn JH, Saphire EO, Crozier I
• Current Landscape of Uveitis Specialists in the United States.
  Journal of academic ophthalmology (2017) 2022 Tsui E, Crowell EL, Gangaputra S, Moussa K, Shantha JG, Shusko AJ, Thompson IA, Pham DC, Jackson NJ, Venkat AG
• Relapse and Remission in Children With Chronic Noninfectious Uveitis Treated With Methotrexate.
  The Journal of rheumatology 2022 McCracken C, Shantha JG, Yeh S, Jenkins K, Rouster-Stevens KA, Lambert SR, Prahalad S, Drews-Botsch C, Angeles-Han ST
• Bilateral anterior and intermediate uveitis in SARS-CoV-2 associated multisystem inflammatory syndrome in a pediatric patient.
  Pediatric rheumatology online journal 2022 Shantha J, Reddy AK, Sura A, Tsang A, Moussa K, Acharya N, Gonzales J, Doan T
• Refractive Outcomes of Combined Cataract Surgery and Vitrectomy Compared to Cataract Surgery Alone.
  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2022 Kokame GT, Tanji TT, Yanagihara RT, Shantha JG, Nirwan RS, Tanji TM
• Prevalence of Epstein-Barr Virus in Patients with Intraocular Inflammation.
  Ocular immunology and inflammation 2022 Moussa K, Gonzales JA, Shantha J, Acharya NR, Doan T
• Comprehensive Assessment of Quality of Life, Functioning, and Mental Health in Children With Juvenile Idiopathic Arthritis and Noninfectious Uveitis.
  Arthritis care & research 2022 McDonald J, Cassedy A, Altaye M, Andringa J, Cooper AM, Drews-Botsch C, Engelhard G, Hennard T, Holland GN, Jenkins K, Lambert SR, Lipscomb J, McCracken C, McCurdy DK, Mwase N, Prahalad S, Shantha J, …
• Ophthalmic sequelae and psychosocial impact in pediatric ebola survivors.
  EClinicalMedicine 2022 Shantha JG, Canady D, Hartley C, Cassedy A, Miller C, Angeles-Han ST, Harrison-Williams LCM, Vandy MJ, Weil N, Bastien G, Yeh S
• Case Report: Delayed Onset Multi-Organ Toxicities in a Melanoma Patient Achieving Complete Response to BRAF/MEK Inhibition.
  Frontiers in oncology 2022 Knochelmann HM, Ware MB, Rali A, Linderman S, Shantha JG, Lawson DH, Yushak M, Swerlick R, Paulos CM, Yeh S, Kudchadkar R
• Cytomegalovirus retinitis in the highly active anti-retroviral therapy era.
  Annals of eye science 2022 Ude IN, Yeh S, Shantha JG
• Risk Factors for Retinal Detachment in Acute Retinal Necrosis.
  Ophthalmology. Retina 2022 Bavinger JC, Anthony CL, Lindeke-Myers AT, Lynch S, Xu LT, Barnett J, Levine D, Patel P, Shah R, Jain N, Rao P, Hendrick A, Cribbs BE, Yan J, Hubbard GB, Shantha JG, O'Keefe GD, Yeh S
• In office management of optic capture of scleral fixated posterior chamber intraocular lenses.
  American journal of ophthalmology case reports 2022 Kokame GT, Card K, Pisig AU, Shantha JG
• Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma.
  International journal of retina and vitreous 2021 Anthony CL, Bavinger JC, Shantha JG, O'Keefe GD, Pearce WA, Voloschin A, Grossniklaus HE, Yeh S
• INVOLUTION OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION AFTER ENDOPHTHALMITIS.
  Retinal cases & brief reports 2021 Kokame GT, Yannuzzi NA, Shantha JG, Yamane M, Relhan N, Gross J, Ryan EH, Flynn HW
• Uveitis in Children and Adolescents.
  Rheumatic diseases clinics of North America 2021 Chang MH, Shantha JG, Fondriest JJ, Lo MS, Angeles-Han ST
• Cytopathology of Vitreous Specimens in Acute Retinal Necrosis.
  Ocular immunology and inflammation 2021 Hojjatie SL, Shantha JG, O'Keefe GD, Kraft CS, Voloschin A, Grossniklaus H, Yeh S
• Implementation of the Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) study: Lessons learned for vision health systems strengthening in Sierra Leone.
  PloS one 2021 Shantha JG, Crozier I, Kraft CS, Grant DG, Goba A, Hayek BR, Hartley C, Barnes KG, Uyeki TM, Schieffelin J, Garry RF, Bausch DG, Farmer PE, Mattia JG, Vandy MJ, Yeh S, EVICT Study Investigators
• Assessment of retinal microvascular health by optical coherence tomography angiography among persons with HIV.
  AIDS (London, England) 2021 Collins LF, Shantha JG, Nesper PL, Sheth AN, Fawzi AA, Yeh S, Ofotokun I
• Update on biologic therapies for juvenile idiopathic arthritis-associated uveitis.
  Annals of eye science 2021 Thomas J, Kuthyar S, Shantha JG, Angeles-Han ST, Yeh S
• Retinopathy and Systemic Disease Morbidity in Severe COVID-19.
  Ocular immunology and inflammation 2021 Shantha JG, Auld SC, Anthony C, Ward L, Adelman MW, Maier CL, Price KW, Jacob JT, Fashina T, Randleman C, Xu LT, Barnett J, Sadan O, Kandiah PA, Varkey JB, Kraft CS, Rouphael N, Linderman S, Ahmed R, …
• Varicella zoster virus anterior uveitis complicated by thalamic stroke.
  Journal of ophthalmic inflammation and infection 2021 Anthony CL, Costarides AP, Yeh S, Shantha JG
• World Health Organization High Priority Pathogens: Ophthalmic Disease Findings and Vision Health Perspectives.
  Pathogens (Basel, Switzerland) 2021 Kuthyar S, Anthony CL, Fashina T, Yeh S, Shantha JG
• Long-term Management of Panuveitis and Choroidal Mass Associated with Rosai Dorfman Disease with Pegylated Interferon.
  Ocular immunology and inflammation 2021 Kim L, Bavinger JC, Shantha JG, Costarides A, Grossniklaus HE, Yeh S
• Posterior Segment Ophthalmic Manifestations in Ebola Survivors, Sierra Leone.
  Ophthalmology 2021 Berry DE, Bavinger JC, Fernandes A, Mattia JG, Mustapha J, Harrison-Williams L, Teshome M, Vandy MJ, Shantha JG, Yeh S, Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study Investigators
• Efficacy and Safety Outcomes of Cataract Surgery in Survivors of Ebola Virus Disease: 12-Month Results From the PREVAIL VII Study.
  Translational vision science & technology 2021 Eghrari AO, Shantha JG, Ross RD, Ryn CV, Crozier I, Hayek B, Gradin D, Roberts B, Prakalapakorn SG, Amegashie F, Nishant K, Singh G, Dolo R, Fankhauser J, Burkholder B, Pettitt J, Gross R, Brady T, …
• Ophthalmic manifestations and vision impairment in Lassa fever survivors.
  PloS one 2020 Li AL, Grant D, Gbakie M, Kanneh L, Mustafa I, Bond N, Engel E, Schieffelin J, Vandy MJ, Yeh S, Shantha JG
• Outcomes of Infectious Endophthalmitis in Patients with Systemic Antibiotic Allergies to Penicillins, Cephalosporins, or Vancomycin.
  Ophthalmology. Retina 2020 Meyer BI, Berry DE, Cribbs BE, Hendrick A, Jain N, Hubbard GB, O'Keefe G, Patel PS, Shantha JG, Yan J, Yeh S, Rao P
• Systemic Lupus Erythematosus-associated Retinal Vasculitis Treated with Adalimumab.
  Ocular immunology and inflammation 2020 Kuthyar S, Barnes AC, Bhawal J, Christiansen J, Shantha JG, Yeh S
• Ebola, COVID-19, and emerging infectious disease: lessons learned and future preparedness.
  Current opinion in ophthalmology 2020 Bavinger JC, Shantha JG, Yeh S
• Ophthalmic and psychosocial sequelae in Ebola virus disease survivors: ongoing need for health systems strengthening across disciplines.
  Expert review of anti-infective therapy 2020 Canady D, Weil NC, Miller C, Shantha JG, Bastien G, Yeh S
• Long-term multimodal imaging in acute posterior multifocal placoid pigment epitheliopathy and association with coxsackievirus exposure.
  PloS one 2020 Li AL, Palejwala NV, Shantha JG, O'Keefe G, Lee CS, Albini T, Yeh S
• SARS-CoV-2 and the Eye: Implications for the Retina Specialist from Human Coronavirus Outbreaks and Animal Models.
  Journal of vitreoretinal diseases 2020 FRCOphth AK, Shantha JG, Olivia Li JP, Faia LJ, Hartley C, Kuthyar S, Albini TA, Wu H, Chodosh J, Ting DSW, Yeh S
• Outcomes of Combination Systemic and Intravitreal Antiviral Therapy for Acute Retinal Necrosis.
  Ophthalmology. Retina 2020 Debiec MR, Lindeke-Myers AT, Shantha JG, Bergstrom CS, Hubbard GB, Yeh S
• Approach to Cataract Surgery in an Ebola Virus Disease Survivor with Prior Ocular Viral Persistence.
  Emerging infectious diseases 2020 Wells JR, Crozier I, Kraft CS, Sexton ME, Hill CE, Ribner BS, Bavari S, Palacios G, Pearce WA, Van Gelder R, Grossniklaus H, Cazares L, Zeng X, Shantha JG, Yeh S
• Toxoplasmosis chorioretinitis mimicking acute retinal necrosis associated with local corticosteroid.
  International journal of retina and vitreous 2020 Crosson JN, Kuthyar S, Shantha JG, Debiec MR, Laird PW, Hwang CS, Grossniklaus HE, Yeh S
• Pathogenesis of Uveitis in Ebola Virus Disease Survivors: Evolving Understanding from Outbreaks to Animal Models.
  Microorganisms 2020 Hartley C, Bavinger JC, Kuthyar S, Shantha JG, Yeh S
• Preparedness among Ophthalmologists: During and Beyond the COVID-19 Pandemic.
  Ophthalmology 2020 Olivia Li JP, Shantha J, Wong TY, Wong EY, Mehta J, Lin H, Lin X, Strouthidis NG, Park KH, Fung AT, McLeod SD, Busin M, Parke DW, Holland GN, Chodosh J, Yeh S, Ting DSW
• Presumed ocular histoplasmosis syndrome in a commercially insured population, United States.
  PloS one 2020 Benedict K, Shantha JG, Yeh S, Beer KD, Jackson BR
• Successful Treatment of Full-Thickness Macular Hole in Polypoidal Choroidal Vasculopathy with Anti-VEGF Therapy.
  Journal of vitreoretinal diseases 2020 Lindeke-Myers A, Kokame GT, Yeh S, Shantha J
• Relapsing Uveitis due to Human T-lymphotropic Virus Type 1 in a Patient Living With HIV Diagnosed by Metagenomic Deep Sequencing.
  Open forum infectious diseases 2020 Phadke VK, Shantha JG, O'Keefe G
• Update on the Management of Acute Retinal Necrosis.
  Ophthalmic surgery, lasers & imaging retina 2019 Li AL, Fine HF, Shantha JG, Yeh S
• Letermovir for the Management of Cytomegalovirus-associated Uveitis.
  Ocular immunology and inflammation 2019 Tsui E, Gonzales JA, Shantha JG, Acharya N, Doan T
• Update on the management of uveitis in children: an overview for the clinician.
  Expert review of ophthalmology 2019 Kim L, Li A, Angeles-Han S, Yeh S, Shantha J
• Insights From 2 Outbreaks in Southeastern Brazil: Yellow Fever Retinopathy.
  JAMA ophthalmology 2019 Shantha JG, Yeh S, Acharya N
• Ocular complications in Ebola virus disease survivors: the importance of continuing care in West Africa.
  Expert review of ophthalmology 2019 Berry DE, Li AL, Yeh S, Shantha JG
• Strength of Association between Pentosan Polysulfate and a Novel Maculopathy.
  Ophthalmology 2019 Hanif AM, Shah R, Yan J, Varghese JS, Patel SA, Cribbs BE, O'Keefe G, Hendrick AM, Shantha JG, Hubbard GB, Patel PS, Rao P, Yeh S, Jain N
• Association of Ocular Inflammation and Rubella Virus Persistence.
  JAMA ophthalmology 2019 Gonzales JA, Hinterwirth A, Shantha J, Wang K, Zhong L, Cummings M, Qian Y, Wilson MR, Acharya NR, Doan T
• Development of a screening eye clinic for Ebola virus disease survivors: Lessons learned and rapid implementation at ELWA Hospital in Monrovia, Liberia 2015.
  PLoS neglected tropical diseases 2019 Shantha JG, Hayek BR, Crozier I, Gargu C, Dolo R, Brown J, Fankhauser J, Yeh S
• Capnocytophaga Keratitis: Clinical Presentation and Use of Metagenomic Deep Sequencing for Diagnosis.
  Cornea 2019 Seitzman GD, Thulasi P, Hinterwirth A, Chen C, Shantha J, Doan T
• Cataract management in Ebola virus disease survivors: clinical and scientific implications.
  Future virology 2019 Li AL, Berry DE, Shantha JG, Yeh S
• Ocular manifestations of bartonellosis.
  Current opinion in ophthalmology 2018 Mabra D, Yeh S, Shantha JG
• CYTOMEGALOVIRUS RETINITIS ASSOCIATED WITH OCCLUSIVE VASCULOPATHY IN AN ELDERLY, HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE MAN.
  Retinal cases & brief reports 2018 Moussa K, Doan T, Stewart JM, Shantha J, Gonzales J, Acharya N, Cunningham ET
• Clinical Manifestations and Pathogenesis of Uveitis in Ebola Virus Disease Survivors.
  Ocular immunology and inflammation 2018 Yeh S, Shantha JG, Hayek B, Crozier I, Smith JR
• Blurry Vision and Eye Pain After Pterygium Surgery.
  JAMA ophthalmology 2018 Moussa K, Shantha J, Schallhorn JM
• Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Reverse Transcription-Polymerase Chain Reaction and Cataract Surgery Outcomes of Ebola Survivors in Sierra Leone.
  EBioMedicine 2018 Shantha JG, Mattia JG, Goba A, Barnes KG, Ebrahim FK, Kraft CS, Hayek BR, Hartnett JN, Shaffer JG, Schieffelin JS, Sandi JD, Momoh M, Jalloh S, Grant DS, Dierberg K, Chang J, Mishra S, Chan AK, Fowler…
• Reply.
  Ophthalmology 2018 Shantha JG, Crozier I, Hayek BR, Bruce BB, Fankhauser J, Yeh S
• Combination nivolumab- and cabiralizumab-associated acute bilateral anterior and posterior scleritis and anterior uveitis.
  American journal of ophthalmology case reports 2018 Gonzales JA, Shantha J, Acharya NR
• Long-term Outcome of Pars Plana Vitrectomy and Sutured Scleral-Fixated Posterior Chamber Intraocular Lens Implantation or Repositioning.
  American journal of ophthalmology 2018 Kokame GT, Yanagihara RT, Shantha JG, Kaneko KN
• Spectral-Domain Optical Coherence Tomography Angiography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy.
  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2017 de Carlo TE, Kokame GT, Shantha JG, Lai JC, Wee R
• Polypoidal Choroidal Vasculopathy in Highly Myopic Eyes with Elongated Axial Length.
  The open ophthalmology journal 2017 Kokame GT, Tom ES, Shantha JG, Kaneko KN
• Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas.
  The British journal of ophthalmology 2017 Gonzales J, Doan T, Shantha JG, Bloomer M, Wilson MR, DeRisi JL, Acharya N
• An update on ocular complications of Ebola virus disease.
  Current opinion in ophthalmology 2017 Shantha JG, Crozier I, Yeh S
• Ophthalmic Manifestations and Causes of Vision Impairment in Ebola Virus Disease Survivors in Monrovia, Liberia.
  Ophthalmology 2016 Shantha JG, Crozier I, Hayek BR, Bruce BB, Gargu C, Brown J, Fankhauser J, Yeh S
• Ebola virus disease and the eye.
  Current opinion in ophthalmology 2016 Shantha JG, Yeh S, Nguyen QD
• Long-term Management of Panuveitis and Iris Heterochromia in an Ebola Survivor.
  Ophthalmology 2016 Shantha JG, Crozier I, Varkey JB, Kraft CS, Lyon GM, Mehta AK, Carlson RD, Hill CE, Kumar G, Debiec MR, Patel PS, Olsen TW, Nussenblatt RB, Martin DF, Ströher U, Uyeki TM, Ribner BS, Smith JR, Yeh S
• En Face Spectral-Domain Optical Coherence Tomography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy.
  Ophthalmic surgery, lasers & imaging retina 2016 Kokame GT, Shantha JG, Hirai K, Ayabe J
• Prospective clinical trial of Intravitreal aflibercept treatment for PolypoIdal choroidal vasculopathy with hemorrhage or exudation (EPIC study): 6 month results.
  BMC ophthalmology 2016 Kokame GT, Lai JC, Wee R, Yanagihara R, Shantha JG, Ayabe J, Hirai K
• Choroidal Neovascularization Associated With Birdshot Chorioretinopathy.
  Ophthalmic surgery, lasers & imaging retina 2016 Shantha JG, Ho VY, Patel P, Forooghian F, Yeh S
• Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study.
  The Lancet. Infectious diseases 2015 Mattia JG, Vandy MJ, Chang JC, Platt DE, Dierberg K, Bausch DG, Brooks T, Conteh S, Crozier I, Fowler RA, Kamara AP, Kang C, Mahadevan S, Mansaray Y, Marcell L, McKay G, O'Dempsey T, Parris V, Pinto R…
• Secondary Vitreoretinal Lymphoma Masquerading as Acute Retinal Necrosis.
  Ophthalmic surgery, lasers & imaging retina 2015 Ryan ME, Shantha JG, Grossniklaus HE, Yeh S
• Persistence of Ebola Virus in Ocular Fluid during Convalescence.
  The New England journal of medicine 2015 Varkey JB, Shantha JG, Crozier I, Kraft CS, Lyon GM, Mehta AK, Kumar G, Smith JR, Kainulainen MH, Whitmer S, Ströher U, Uyeki TM, Ribner BS, Yeh S
• Advances in the management of acute retinal necrosis.
  International ophthalmology clinics 2015 Shantha JG, Weissman HM, Debiec MR, Albini TA, Yeh S
• Emerging causes of viral-associated uveitis.
  International ophthalmology clinics 2015 Connors DB, Shantha JG, Yeh S
• Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting.
  American journal of ophthalmology 2014 Yen M, Chen J, Ausayakhun S, Kunavisarut P, Vichitvejpaisal P, Ausayakhun S, Jirawison C, Shantha J, Holland GN, Heiden D, Margolis TP, Keenan JD
• American Society of Ophthalmic Plastic and Reconstructive Surgery fellowship survey: fellows selection criteria for training programs.
  Ophthalmic plastic and reconstructive surgery 2013 Shantha JG, Shulman B, Gonzalez M, Hink EM, Durairaj VD
• Bilateral proptosis as initial manifestation of mantle cell lymphoma.
  The American journal of medicine 2013 Walia SS, Stelton CR, Shantha JG, Connors DB, Walia HS
• CD4 count is predictive of outcome in HIV-positive patients undergoing abdominal operations.
  American journal of surgery 2010 Deneve JL, Shantha JG, Page AJ, Wyrzykowski AD, Rozycki GS, Feliciano DV