Jessica Neely, MD
Assistant Professor
Pediatrics
School of Medicine

Dr. Neely is a pediatric rheumatologist who studies a rare pediatric condition known as juvenile dermatomyositis using multi-modal single cell technologies of biological samples collected from her patients. Her research seeks to identify novel treatment targets and biomarkers for this condition to develop precision medicine approaches to care. Her work also seeks to better understand the immune dysregulation that leads to juvenile dermatomyositis.

Education & Training

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• Pediatric Rheumatology Fellowship University of California, San Francisco 06/2019
• Pediatric Residency University of California, San Francisco 06/2016
• MD Medicine University of Kentucky College of Medicine 05/2013

Websites

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• The Next Level of Rare Disease Care, How UCSF is tackling juvenile dermatomyositis (give.ucsfbenioffchildrens.org)
• Juvenile Myositis Precision Medicine (JuMP) Biorepository (juvenilemyositisstudy.ucsf.edu)
• Center of Excellence, Improving Juvenile Myositis Program UCSF Precision (I JuMP UP) (juvenilemyositis.ucsf.edu)

Publications (12)

Top publication keywords:
Synovial MembraneRegistriesAnemia, Hemolytic, AutoimmuneUltraviolet RaysRheumatologyReceptors, ThrombopoietinSkinLupus Erythematosus, SystemicScleroderma, SystemicDermatomyositisMyositisPrecision MedicineEnvironmental ExposureArthritis, JuvenilePurpura, Thrombocytopenic, Idiopathic

• Gene expression meta-analysis reveals aging and cellular senescence signatures in scleroderma-associated interstitial lung disease.
  Frontiers in immunology 2024 Yang MM, Lee S, Neely J, Hinchcliff M, Wolters PJ, Sirota M
• Coordinated immune dysregulation in Juvenile Dermatomyositis revealed by single-cell genomics.
  bioRxiv : the preprint server for biology 2023 Rabadam G, Wibrand C, Flynn E, Hartoularos GC, Sun Y, Ye CJ, Kim S, Gartner Z, Sirota M, Neely J
• Baseline characteristics of children with juvenile dermatomyositis enrolled in the first year of the new Childhood Arthritis and Rheumatology Research Alliance registry.
  Pediatric rheumatology online journal 2022 Neely J, Ardalan K, Huber A, Kim S, Childhood Arthritis and Rheumatology Research Alliance Investigators
• Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity.
  Frontiers in immunology 2022 Neely J, Hartoularos G, Bunis D, Sun Y, Lee D, Kim S, Ye CJ, Sirota M
• Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis.
  Frontiers in immunology 2021 Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M

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• Access to Care and Diagnostic Delays in Juvenile Dermatomyositis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
  ACR open rheumatology 2021 Neely J, Shalen J, Sturrock H, Kim S, Childhood Arthritis and Rheumatology Research Alliance Investigators
• Advances Toward Precision Medicine in Juvenile Dermatomyositis.
  Current rheumatology reports 2019 Neely J, Kim S
• Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues.
  ACR open rheumatology 2019 Neely J, Rychkov D, Paranjpe M, Waterfield M, Kim S, Sirota M
• Association of Short-Term Ultraviolet Radiation Exposure and Disease Severity in Juvenile Dermatomyositis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
  Arthritis care & research 2019 Neely J, Long CS, Sturrock H, Kim S, Childhood Arthritis and Rheumatology Research Alliance Registry Investigators
• Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant Patients.
  Frontiers in pediatrics 2019 Neely JA, Dvorak CC, Pantell MS, Melton A, Huang JN, Shimano KA
• Autoimmune haemolytic anaemia and autoimmune thrombocytopenia in childhood-onset systemic lupus erythematosus: updates on pathogenesis and treatment.
  Current opinion in rheumatology 2018 Neely J, von Scheven E
• Gene therapy for haemophilia.
  The Cochrane database of systematic reviews 2014 Sharma A, Easow Mathew M, Sriganesh V, Neely JA, Kalipatnapu S