Jessica De Leon, MD
Assistant Professor
Neurology
School of Medicine

The underlying goal of my work is to improve dementia diagnosis in communities of different language and sociocultural backgrounds.

• Frontotemporal dementia: A unique window on the functional role of the temporal lobes.
  Handbook of clinical neurology 2022 Borghesani V, DeLeon J, Gorno-Tempini ML
• Children with developmental dyslexia show elevated parasympathetic nervous system activity at rest and greater cardiac deceleration during an empathy task.
  Biological psychology 2021 Palser ER, Morris NA, Roy ARK, Holley SR, Veziris CR, Watson C, Deleon J, Miller ZA, Miller BL, Gorno-Tempini ML, Sturm VE
• Tonal and orthographic analysis in a Cantonese-speaking individual with nonfluent/agrammatic variant primary progressive aphasia.
  Neurocase 2021 Tee BL, Deleon J, Chen Li Ying LK, Miller BL, Y Lo R, Europa E, Sudarsan S, Grasso S, Gorno-Tempini ML
• Functional and morphological correlates of developmental dyslexia: A multimodal investigation of the ventral occipitotemporal cortex.
  Journal of neuroimaging : official journal of the American Society of Neuroimaging 2021 Borghesani V, Wang C, Watson C, Bouhali F, Caverzasi E, Battistella G, Bogley R, Yabut NA, Deleon J, Miller ZA, Hoeft F, Mandelli ML, Gorno-Tempini ML
• Dissociating nouns and verbs in temporal and perisylvian networks: Evidence from neurodegenerative diseases.
  Cortex; a journal devoted to the study of the nervous system and behavior 2021 Lukic S, Borghesani V, Weis E, Welch A, Bogley R, Neuhaus J, Deleon J, Miller ZA, Kramer JH, Miller BL, Dronkers NF, Gorno-Tempini ML
• Enhanced visceromotor emotional reactivity in dyslexia and its relation to salience network connectivity.
  Cortex; a journal devoted to the study of the nervous system and behavior 2020 Sturm VE, Roy ARK, Datta S, Wang C, Sible IJ, Holley SR, Watson C, Palser ER, Morris NA, Battistella G, Rah E, Meyer M, Pakvasa M, Mandelli ML, Deleon J, Hoeft F, Caverzasi E, Miller ZA, Shapiro KA, …
• Effects of bilingualism on age at onset in two clinical Alzheimer's disease variants.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 de Leon J, Grasso SM, Welch A, Miller Z, Shwe W, Rabinovici GD, Miller BL, Henry ML, Gorno-Tempini ML
• Speech production differences in English and Italian speakers with nonfluent variant PPA.
  Neurology 2020 Canu E, Agosta F, Battistella G, Spinelli EG, DeLeon J, Welch AE, Mandelli ML, Hubbard HI, Moro A, Magnani G, Cappa SF, Miller BL, Filippi M, Gorno-Tempini ML
• Task-Free Functional Language Networks: Reproducibility and Clinical Application.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Battistella G, Borghesani V, Henry M, Shwe W, Lauricella M, Miller Z, Deleon J, Miller BL, Dronkers N, Brambati SM, Seeley WW, Mandelli ML, Gorno-Tempini ML
• Verbal Semantics and the Left Dorsolateral Anterior Temporal Lobe: A Longitudinal Case of Bilateral Temporal Degeneration.
  Aphasiology 2019 Vonk JMJ, Borghesani V, Battistella G, Younes K, DeLeon J, Welch A, Hubbard HI, Miller ZA, Miller BL, Gorno-Tempini ML
• Atypical clinical features associated with mixed pathology in a case of non-fluent variant primary progressive aphasia.
  Neurocase 2019 De Leon J, Mandelli ML, Nolan A, Miller ZA, Mead C, Watson C, Welch AE, Henry ML, Bourakova V, La Joie R, Bajorek LP, Grinberg L, Rabinovici G, Miller BL, Gorno-Tempini ML
• Differential intrinsic functional connectivity changes in semantic variant primary progressive aphasia.
  NeuroImage. Clinical 2019 Battistella G, Henry M, Gesierich B, Wilson SM, Borghesani V, Shwe W, Miller Z, Deleon J, Miller BL, Jovicich J, Papinutto N, Dronkers NF, Seeley WW, Mandelli ML, Gorno-Tempini ML
• Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA.
  Cortex; a journal devoted to the study of the nervous system and behavior 2018 Mandelli ML, Welch AE, Vilaplana E, Watson C, Battistella G, Brown JA, Possin KL, Hubbard HI, Miller ZA, Henry ML, Marx GA, Santos-Santos MA, Bajorek LP, Fortea J, Boxer A, Rabinovici G, Lee S, Deleon…
• Frontotemporal dementia.
  Handbook of clinical neurology 2018 Deleon J, Miller BL
• Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.
  Brain : a journal of neurology 2015 Baets J, Duan X, Wu Y, Smith G, Seeley WW, Mademan I, McGrath NM, Beadell NC, Khoury J, Botuyan MV, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, Liu YT, Senderek J, Weis J, Van den Bergh P, Merrill …
• Elicitation of specific syntactic structures in primary progressive aphasia.
  Brain and language 2012 Deleon J, Gesierich B, Besbris M, Ogar J, Henry ML, Miller BL, Gorno-Tempini ML, Wilson SM
• Syntactic processing depends on dorsal language tracts.
  Neuron 2011 Wilson SM, Galantucci S, Tartaglia MC, Rising K, Patterson DK, Henry ML, Ogar JM, DeLeon J, Miller BL, Gorno-Tempini ML
• Adult glial precursor proliferation in mutant SOD1G93A mice.
  Glia 2008 Magnus T, Carmen J, Deleon J, Xue H, Pardo AC, Lepore AC, Mattson MP, Rao MS, Maragakis NJ
• Neural regions essential for distinct cognitive processes underlying picture naming.
  Brain : a journal of neurology 2007 DeLeon J, Gottesman RF, Kleinman JT, Newhart M, Davis C, Heidler-Gary J, Lee A, Hillis AE