Jeremy Reiter, MD, PhD
Professor & Chair, Department of Biochemistry and Biophysics
Biochemistry and Biophysics
School of Medicine

1. The discovery that Smoothened, a critical component of the Hedgehog pathway, localizes to and works in cilia. This was the first demonstration that the Hedgehog signal transduction machinery functions at cilia. 2. They were the first to show that cancers can be ciliated and that cancers can require cilia for growth. 3. They helped show that the region at the base of the cilium called the transition zone is a gate that controls ciliary composition. For example, the transition zone regulates the ciliary localization of Smoothened and, therefore, is required for Hedgehog signaling. 4. They identified many transition zone components and discovered that some ciliopathies are caused by inherited human mutations in these transition zone components. 5. They found a phosphoinositide that marks the ciliary membrane and helps direct which proteins localize to cilia. This was the first identification of a specific cilia-enriched lipid. 6. They investigated how cilia regulate adult tissue homeostasis. Recently, they have shown how cilia of hypothalamic neurons signal to regulate satiety and how cilia restrict adipogenesis.

• GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
  Nature structural & molecular biology 2024 Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay…
• ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function.
  bioRxiv : the preprint server for biology 2023 Ha K, Loeb GB, Park M, Pinedo A, Park CH, Brandes N, Ritu F, Ye CJ, Reiter JF, Delling M
• Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
  Cell reports 2023 Hoi KK, Xia W, Wei MM, Ulloa Navas MJ, Garcia Verdugo JM, Nachury MV, Reiter JF, Fancy SPJ
• Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease.
  Physiological genomics 2023 Jung HJ, Dixon EE, Coleman R, Watnick T, Reiter JF, Outeda P, Cebotaru V, Woodward OM, Welling PA
• Rab35 is required for embryonic development and kidney and ureter homeostasis through regulation of epithelial cell junctions.
  bioRxiv : the preprint server for biology 2023 Clearman KR, Timpratoom N, Patel D, Rains AB, Haycraft CJ, Croyle MJ, Reiter JF, Yoder BK
• An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals.
  Current biology : CB 2023 Coyle MC, Tajima AM, Leon F, Choksi SP, Yang A, Espinoza S, Hughes TR, Reiter JF, Booth DS, King N
• Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma.
  Research square 2023 Daggubati V, Vykunta A, Choudhury A, Qadeer Z, Mirchia K, Saulnier O, Zakimi N, Hines K, Paul M, Wang L, Jura N, Xu L, Reiter J, Taylor M, Weiss W, Raleigh D
• GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
  bioRxiv : the preprint server for biology 2023 Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay …
• Physiological Condition-Dependent Changes in Ciliary GPCR Localization in the Brain.
  eNeuro 2023 Brewer KM, Engle SE, Bansal R, Brewer KK, Jasso KR, McIntyre JC, Vaisse C, Reiter JF, Berbari NF
• Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
  eLife 2023 Hall EA, Kumar D, Prosser SL, Yeyati PL, Herranz-Pérez V, García-Verdugo JM, Rose L, McKie L, Dodd DO, Tennant PA, Megaw R, Murphy LC, Ferreira MF, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter…
• MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R.
  JCI insight 2023 Bernard A, Ojeda Naharros I, Yue X, Mifsud F, Blake A, Bourgain-Guglielmetti F, Ciprin J, Zhang S, McDaid E, Kim K, Nachury MV, Reiter JF, Vaisse C
• Zika virus alters centrosome organization to suppress the innate immune response.
  EMBO reports 2022 Kodani A, Knopp KA, Di Lullo E, Retallack H, Kriegstein AR, DeRisi JL, Reiter JF
• A kinesin mimics DNA.
  Nature cell biology 2022 Kumar D, Reiter JF
• The Intimate Connection Between Lipids and Hedgehog Signaling.
  Frontiers in cell and developmental biology 2022 Nguyen TD, Truong ME, Reiter JF
• The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
  Science (New York, N.Y.) 2022 Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, …
• Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity.
  Developmental cell 2021 Xie C, Abrams SR, Herranz-Pérez V, García-Verdugo JM, Reiter JF
• ATXN10 Is Required for Embryonic Heart Development and Maintenance of Epithelial Cell Phenotypes in the Adult Kidney and Pancreas.
  Frontiers in cell and developmental biology 2021 Bentley-Ford MR, Andersen RS, Croyle MJ, Haycraft CJ, Clearman KR, Foote JB, Reiter JF, Yoder BK
• Ciliary Hedgehog signaling regulates cell survival to build the facial midline.
  eLife 2021 Abrams SR, Reiter JF
• A ciliopathy complex builds distal appendages to initiate ciliogenesis.
  The Journal of cell biology 2021 Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
• Label-retention expansion microscopy.
  The Journal of cell biology 2021 Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B
• Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight.
  The Journal of clinical investigation 2021 Wang Y, Bernard A, Comblain F, Yue X, Paillart C, Zhang S, Reiter JF, Vaisse C
• Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models.
  The Journal of clinical investigation 2021 Daggubati V, Hochstelter J, Bommireddy A, Choudhury A, Krup AL, Kaur P, Tong P, Li A, Xu L, Reiter JF, Raleigh DR
• Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
  The Journal of cell biology 2021 Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR
• How the centriole builds its cilium: of mothers, daughters, and the acquisition of appendages.
  Current opinion in structural biology 2020 Kumar D, Reiter J
• A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development.
  eLife 2020 Hasenpusch-Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, Abrams SR, Reiter JF, Schneider-Maunoury S, Theil T
• Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
  Cell 2019 Hilgendorf KI, Johnson CT, Mezger A, Rice SL, Norris AM, Demeter J, Greenleaf WJ, Reiter JF, Kopinke D, Jackson PK
• Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
  Cell 2019 Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T
• SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.
  The Journal of cell biology 2019 Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF
• Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures.
  Frontiers in cellular neuroscience 2019 Bansal R, Engle SE, Antonellis PJ, Whitehouse LS, Baucum AJ, Cummins TR, Reiter JF, Berbari NF
• Deformed alignment of super-resolution images for semi-flexible structures.
  PloS one 2019 Shi X, Garcia G, Wang Y, Reiter JF, Huang B
• Misactivation of Hedgehog signaling causes inherited and sporadic cancers.
  The Journal of clinical investigation 2019 Raleigh DR, Reiter JF
• Cilia-Associated Oxysterols Activate Smoothened.
  Molecular cell 2018 Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald …
• Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination.
  Neuron 2018 Park SM, Lim JS, Ramakrishina S, Kim SH, Kim WK, Lee J, Kang HC, Reiter JF, Kim DS, Kim HH, Lee JH
• How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In.
  Current biology : CB 2018 Garcia G, Raleigh DR, Reiter JF
• Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity.
  Nature genetics 2018 Siljee JE, Wang Y, Bernard AA, Ersoy BA, Zhang S, Marley A, Von Zastrow M, Reiter JF, Vaisse C
• Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.
  Developmental cell 2017 Sigg MA, Menchen T, Lee C, Johnson J, Jungnickel MK, Choksi SP, Garcia G, Busengdal H, Dougherty GW, Pennekamp P, Werner C, Rentzsch F, Florman HM, Krogan N, Wallingford JB, Omran H, Reiter JF
• Hedgehog signaling drives medulloblastoma growth via CDK6.
  The Journal of clinical investigation 2017 Raleigh DR, Choksi PK, Krup AL, Mayer W, Santos N, Reiter JF
• Erratum: Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome.
  Nature cell biology 2017 Shi X, Garcia G, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF
• Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome.
  Nature cell biology 2017 Shi X, Garcia G, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF
• Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.
  Cell 2017 Kopinke D, Roberson EC, Reiter JF
• Genes and molecular pathways underpinning ciliopathies.
  Nature reviews. Molecular cell biology 2017 Reiter JF, Leroux MR
• Cilia and Obesity.
  Cold Spring Harbor perspectives in biology 2017 Vaisse C, Reiter JF, Berbari NF
• Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.
  Cold Spring Harbor perspectives in biology 2017 Garcia-Gonzalo FR, Reiter JF
• Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
  Cell 2017 Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T
• Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.
  Neuron 2016 Jayaraman D, Kodani A, Gonzalez DM, Mancias JD, Mochida GH, Vagnoni C, Johnson J, Krogan N, Harper JW, Reiter JF, Yu TW, Bae BI, Walsh CA
• Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.
  Cell 2016 Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA
• A primer on the mouse basal body.
  Cilia 2016 Garcia G, Reiter JF
• MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone.
  PLoS biology 2016 Li C, Jensen VL, Park K, Kennedy J, Garcia-Gonzalo FR, Romani M, De Mori R, Bruel AL, Gaillard D, Doray B, Lopez E, Rivière JB, Faivre L, Thauvin-Robinet C, Reiter JF, Blacque OE, Valente EM, Leroux …
• Endothelial primary cilia inhibit atherosclerosis.
  EMBO reports 2016 Dinsmore C, Reiter JF
• Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.
  PLoS genetics 2015 Yee LE, Garcia-Gonzalo FR, Bowie RV, Li C, Kennedy JK, Ashrafi K, Blacque OE, Leroux MR, Reiter JF
• Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
  Developmental cell 2015 Garcia-Gonzalo FR, Phua SC, Roberson EC, Garcia G, Abedin M, Schurmans S, Inoue T, Reiter JF
• Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.
  eLife 2015 Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF
• TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
  The Journal of cell biology 2015 Roberson EC, Dowdle WE, Ozanturk A, Garcia-Gonzalo FR, Li C, Halbritter J, Elkhartoufi N, Porath JD, Cope H, Ashley-Koch A, Gregory S, Thomas S, Sayer JA, Saunier S, Otto EA, Katsanis N, Davis EE, …
• Ciliary vesicle formation: a prelude to ciliogenesis.
  Developmental cell 2015 Yee LE, Reiter JF
• Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration.
  Cell cycle (Georgetown, Tex.) 2015 Vagnozzi AN, Reiter JF, Wong SY
• Katanin p80 regulates human cortical development by limiting centriole and cilia number.
  Neuron 2014 Hu WF, Pomp O, Ben-Omran T, Kodani A, Henke K, Mochida GH, Yu TW, Woodworth MB, Bonnard C, Raj GS, Tan TT, Hamamy H, Masri A, Shboul M, Al Saffar M, Partlow JN, Al-Dosari M, Alazami A, Alowain M, …
• C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Ye X, Zeng H, Ning G, Reiter JF, Liu A
• A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity.
  Journal of cell science 2014 Santos N, Reiter JF
• Hedgehog signaling controls T cell killing at the immunological synapse.
  Science (New York, N.Y.) 2013 de la Roche M, Ritter AT, Angus KL, Dinsmore C, Earnshaw CH, Reiter JF, Griffiths GM
• Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.
  Development (Cambridge, England) 2013 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY
• Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.
  Journal of molecular endocrinology 2013 D'Amico E, Gayral S, Massart C, Van Sande J, Reiter JF, Dumont JE, Robaye B, Schurmans S
• Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
  The EMBO journal 2013 Kodani A, Salomé Sirerol-Piquer M, Seol A, Garcia-Verdugo JM, Reiter JF
• Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells.
  Cancer research 2012 Spassov DS, Wong CH, Wong SY, Reiter JF, Moasser MM
• Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Wu VM, Chen SC, Arkin MR, Reiter JF
• The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization.
  EMBO reports 2012 Reiter JF, Blacque OE, Leroux MR
• Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access.
  The Journal of cell biology 2012 Garcia-Gonzalo FR, Reiter JF
• A high-fat diet regulates gastrin and acid secretion through primary cilia.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Saqui-Salces M, Dowdle WE, Reiter JF, Merchant JL
• Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.
  PLoS genetics 2012 Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF
• Disruption of a ciliary B9 protein complex causes Meckel syndrome.
  American journal of human genetics 2011 Dowdle WE, Robinson JF, Kneist A, Sirerol-Piquer MS, Frints SG, Corbit KC, Zaghloul NA, Zaghloul NA, van Lijnschoten G, Mulders L, Verver DE, Zerres K, Reed RR, Attié-Bitach T, Johnson CA, García-…
• A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
  Nature genetics 2011 Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, Noriega TR, Seol AD, Robinson JF, Bennett CL, Josifova DJ, García-Verdugo JM, Katsanis N, Hildebrandt F, Reiter JF
• Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.
  Cell 2011 Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, …
• Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
  Development (Cambridge, England) 2011 Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D, Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, Yoder BK
• Wounding mobilizes hair follicle stem cells to form tumors.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Wong SY, Reiter JF
• Crippling SWI-SNF makes tumors GLI-ful.
  Nature medicine 2010 Reiter JF
• The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells.
  Stem cells and development 2010 Hunkapiller J, Singla V, Seol A, Reiter JF
• Tilting at nodal windmills: planar cell polarity positions cilia to tell left from right.
  Developmental cell 2010 Santos N, Reiter JF
• Vive la science! Vive le hérisson!
  EMBO reports 2010 Reiter JF, de Sauvage FJ
• Ofd1, a human disease gene, regulates the length and distal structure of centrioles.
  Developmental cell 2010 Singla V, Romaguera-Ros M, Garcia-Verdugo JM, Reiter JF
• Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.
  Cell stem cell 2010 Walker E, Chang WY, Hunkapiller J, Cagney G, Garcha K, Torchia J, Krogan NJ, Reiter JF, Stanford WL
• Floxin, a resource for genetically engineering mouse ESCs.
  Nature methods 2009 Singla V, Hunkapiller J, Santos N, Seol AD, Norman AR, Wakenight P, Skarnes WC, Reiter JF
• Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.
  Nature medicine 2009 Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH, Dlugosz AA, Reiter JF
• The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling.
  Current biology : CB 2009 Aanstad P, Santos N, Corbit KC, Scherz PJ, Trinh le A, Salvenmoser W, Huisken J, Reiter JF, Stainier DY
• Building it up and taking it down: the regulation of vertebrate ciliogenesis.
  Developmental dynamics : an official publication of the American Association of Anatomists 2008 Santos N, Reiter JF
• A cilium is not a cilium is not a cilium: signaling contributes to ciliary morphological diversity.
  Developmental cell 2008 Reiter JF
• Neur-ons and neur-offs: regulators of neural induction in vertebrate embryos and embryonic stem cells.
  Human molecular genetics 2008 Gaulden J, Reiter JF
• The primary cilium at the crossroads of mammalian hedgehog signaling.
  Current topics in developmental biology 2008 Wong SY, Reiter JF
• Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms.
  Nature cell biology 2007 Corbit KC, Shyer AE, Dowdle WE, Gaulden J, Singla V, Chen MH, Chuang PT, Reiter JF
• Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Reiter JF, Mostov K
• The primary cilium as the cell's antenna: signaling at a sensory organelle.
  Science (New York, N.Y.) 2006 Singla V, Reiter JF
• Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.
  Genes & development 2005 Reiter JF, Skarnes WC
• Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli.
  Developmental biology 2005 May SR, Ashique AM, Karlen M, Wang B, Shen Y, Zarbalis K, Reiter J, Ericson J, Peterson AS
• Vertebrate Smoothened functions at the primary cilium.
  Nature 2005 Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF
• Notch signaling can regulate endoderm formation in zebrafish.
  Developmental dynamics : an official publication of the American Association of Anatomists 2004 Kikuchi Y, Verkade H, Reiter JF, Kim CH, Chitnis AB, Kuroiwa A, Stainier DY
• Multiple roles for Gata5 in zebrafish endoderm formation.
  Development (Cambridge, England) 2001 Reiter JF, Kikuchi Y, Stainier DY
• The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors.
  Genes & development 2000 Kikuchi Y, Trinh LA, Reiter JF, Alexander J, Yelon D, Stainier DY
• Gata5 is required for the development of the heart and endoderm in zebrafish.
  Genes & development 1999 Reiter JF, Alexander J, Rodaway A, Yelon D, Patient R, Holder N, Stainier DY