Jeffrey Whitman, MD
Associate Professor
Laboratory Medicine
School of Medicine

Education & Training

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• Residency Laboratory Medicine University of California, San Francisco 2019
• M.D. Medicine David Geffen School of Medicine, UCLA 2016
• M.S. Biochemistry and Molecular Biology University of California, Riverside 2011
• B.S. Biochemistry University of California, Riverside 2010

Grants and Projects

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• Development of Next-gen Chagas DetectTM Plus Rapid test for sensitive and specific diagnosis of Chagas disease, NIH, 2024-2027
• Host-parasite lipid metabolism in Trypanosoma cruzi-infected cardiac myocytes, NIH, 2020-2025

Publications (30)

Top publication keywords:
Serologic TestsGlycoproteinsPreservation, BiologicalNeuraminidaseAntibodies, ProtozoanTrypanosoma cruziAntigens, ProtozoanEndemic DiseasesHelminthiasisImmunodominant EpitopesBlood DonorsHelminthsAntibody FormationProtozoan ProteinsChagas Disease

• Trypanosoma cruzi trans-sialidase antigens: immunodominance and diagnostic applications.
  Trends in parasitology 2026 Marczak RJ, Bern C, Whitman JD
• A Trypanosoma cruzi trans-sialidase peptide demonstrates high serological prevalence among infected populations across endemic regions.
  The Journal of clinical investigation 2026 Kortbawi HM, Marczak RJ, Rajan JV, Bulaong NL, Pak JE, Wu W, Wang G, Mitchell A, Saxena A, Maheshwari A, Leone RA, Fleischmann CJ, Kelly EA, Teal E, Townsend RL, Stramer SL, Okamoto EE, Sherbuk JE, …
• Rapid COVID-19 Testing of Symptomatic Health Care Personnel: A Strategy for Safely Maintaining the Workforce.
  Journal of occupational and environmental medicine 2024 Tilly MK, McNicholas JE, Whitman JD, Tulsky JP, Villanueva AH, Kang J, Blanc PD, Solomon GM, Jacobson MA
• Chagas disease in immunocompromised patients.
  Clinical microbiology reviews 2024 Clark EH, Messenger LA, Whitman JD, Bern C
• Adaptation of Chagas Disease Screening Recommendations for a Community of At-risk HIV in the United States.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Hayon J, Lupo S, Poveda C, Jones KM, Qian Q, Wu H, Giordano TP, Fleischmann CJ, Bern C, Whitman JD, Clark EH

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• Chagas Disease Diagnostic Practices at Four Major Hospital Systems in California and Texas.
  The Journal of infectious diseases 2024 Kelly EA, Echeverri Alegre JI, Promer K, Hayon J, Iordanov R, Rangwalla K, Zhang JJ, Fang Z, Huang C, Bittencourt CE, Reed S, Andrade RM, Bern C, Clark EH, Whitman JD
• Concordance of Results by Three Chagas Disease Antibody Assays in U.S. Clinical Specimens.
  Journal of clinical microbiology 2023 Moser MS, Fleischmann CJ, Kelly EA, Prince HE, Bern C, Whitman JD
• Evaluation of InBios Chagas Detect Fast, a Novel Enzyme-Linked Immunosorbent Assay for the Detection of Anti-Trypanosoma cruzi Antibodies.
  Journal of clinical microbiology 2023 Moser MS, Fleischmann CJ, Kelly EA, Townsend RL, Stramer SL, Bern C, Whitman JD
• Detection of IgM, IgG, IgA and neutralizing antibody responses to SARS-CoV-2 infection and mRNA vaccination.
  Journal of medical microbiology 2023 Fleischmann CJ, Bulman CA, Yun C, Lynch KL, Wu AHB, Whitman JD
• A Rapid Nucleic Acid Amplification Test-Based, Conditional Release-to-Work Policy for Health Care Personnel With Symptoms Consistent With COVID-19.
  Journal of occupational and environmental medicine 2022 Jacobson MA, Hart C, Huen W, Suarez Guardado G, Villanueva A, Whitman J, Blanc PD
• Screening for Chagas Disease Should Be Included in Entry-to-Care Testing for At-Risk People With Human Immunodeficiency Virus (HIV) Living in the United States.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Clark EH, Marquez C, Whitman JD, Bern C
• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Liu J, Laurie MT, Rubio L, Vazquez SE, Sunshine S, Mitchell AM, Hapte-Selassie M, Mann SA, Pilarowski G, Black D, Marquez C, Rojas S, Lionakis MS, Petersen M, Whitman JD, Jain V, Anderson M, Havlir D,…
• Updated Estimates and Mapping for Prevalence of Chagas Disease among Adults, United States.
  Emerging infectious diseases 2022 Irish A, Whitman JD, Clark EH, Marcus R, Bern C
• Recommendations for Screening and Diagnosis of Chagas Disease in the United States.
  The Journal of infectious diseases 2022 Forsyth CJ, Manne-Goehler J, Bern C, Whitman J, Hochberg NS, Edwards M, Marcus R, Beatty NL, Castro-Sesquen YE, Coyle C, Stigler Granados P, Hamer D, Maguire JH, Gilman RH, Meymandi S
• Diagnostic Value of Nucleocapsid Protein in Blood for SARS-CoV-2 Infection.
  Clinical chemistry 2021 Zhang Y, Ong CM, Yun C, Mo W, Whitman JD, Lynch KL, Wu AHB
• Comparative Performance of Latest-Generation and FDA-Cleared Serology Tests for the Diagnosis of Chagas Disease.
  Journal of clinical microbiology 2021 Kelly EA, Bulman CA, Gunderson EL, Irish AM, Townsend RL, Sakanari JA, Stramer SL, Bern C, Whitman JD
• Significant and sustained decrease in non-SARS-CoV-2 respiratory viral infections during COVID-19 public health interventions.
  medRxiv : the preprint server for health sciences 2021 Whitman JD, Pham P, Bern C, Dekker EM, Haller BL, Jain V, Winston LG
• Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL.
  Cancer discovery 2021 Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera JM, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann BC, Satpathy AT, Manglik…
• SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
  Science translational medicine 2021 Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC
• Areas of Metabolomic Exploration for Helminth Infections.
  ACS infectious diseases 2021 Whitman JD, Sakanari JA, Mitreva M
• SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood.
  Nature communications 2020 Ng DL, Goldgof GM, Shy BR, Levine AG, Balcerek J, Bapat SP, Prostko J, Rodgers M, Coller K, Pearce S, Franz S, Du L, Stone M, Pillai SK, Sotomayor-Gonzalez A, Servellita V, Martin CSS, Granados A, …
• Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
  Nature biotechnology 2020 Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong …
• Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Lynch KL, Whitman JD, Lacanienta NP, Beckerdite EW, Kastner SA, Shy BR, Goldgof GM, Levine AG, Bapat SP, Stramer SL, Esensten JH, Hightower AW, Bern C, Wu AHB
• The endosymbiont Wolbachia rebounds following antibiotic treatment.
  PLoS pathogens 2020 Gunderson EL, Vogel I, Chappell L, Bulman CA, Lim KC, Luo M, Whitman JD, Franklin C, Choi YJ, Lefoulon E, Clark T, Beerntsen B, Slatko B, Mitreva M, Sullivan W, Sakanari JA
• Evaluation of matrix effects and prolonged storage on Trypanosoma cruzi serology in blood donor specimens.
  Transfusion 2020 Whitman JD, Townsend RL, Bern C, Stramer SL
• Chagas Disease in the United States: a Public Health Approach.
  Clinical microbiology reviews 2019 Bern C, Messenger LA, Whitman JD, Maguire JH
• Chagas Disease Serological Test Performance in U.S. Blood Donor Specimens.
  Journal of clinical microbiology 2019 Whitman JD, Bulman CA, Gunderson EL, Irish AM, Townsend RL, Stramer SL, Sakanari JA, Bern C
• Notes from the Field: Unintentional Fentanyl Overdoses Among Persons Who Thought They Were Snorting Cocaine - Fresno, California, January 7, 2019.
  MMWR. Morbidity and mortality weekly report 2019 Armenian P, Whitman JD, Badea A, Johnson W, Drake C, Dhillon SS, Rivera M, Brandehoff N, Lynch KL
• Optimization and Comparison of Information-Dependent Acquisition (IDA) to Sequential Window Acquisition of All Theoretical Fragment Ion Spectra (SWATH) for High-Resolution Mass Spectrometry in Clinical Toxicology.
  Clinical chemistry 2019 Whitman JD, Lynch KL
• Collection and Preservation of Terrestrial Arthropods.
  Methods in molecular biology (Clifton, N.J.) 2019 Whitman JD, Yanega D, Watson CBG, Strode VW