Jeffrey Sall, PhD, MD
Professor
Anesthesia
School of Medicine
Education & Training
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- Postdoctoral Studies Anesthesia & Perioperative Care University of California 2007
- Residency Anesthesia & Perioperative Care University of California 2006
- Internship Internal Medicine University of Iowa 2003
- M.D./Ph.D. Medicine/Neuroscience University of Iowa 2002
- B.S. Biology University of Nebraska 1994
Websites
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- Sall Lab group (anesthesia.ucsf.edu)
- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
- UCSF Anesthesia page (anesthesia.ucsf.edu)
Grants and Projects
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- A Multicenter, Double-blind, Randomized and Placebo-controlled Pivotal Phase 3 Study to Evaluate the Safety and Efficacy of T89 in Prevention and Treatment of Acute Mountain Sickness (AMS) After Rapid Ascent, Tasly Pharmaceutical, 2021-2025
- Comprehensive analysis of developmental cannabis exposure on brain, immune and sensory systems, California Bureau of Cannabis Control, 2022-2024
- A Phase 3/4 Randomized, Double-blind, Dose-ranging Study of the Safety and Efficacy of Dexmedetomidine (Dex) Used with Propofol (Pro) as Needed for Procedural Sedation of Pediatric Subjects =1 Month to <17 Years of Age Undergoing Mri Scans, Pfizer, 2020-2022
- A Double-blind, Randomized and Placebo-controlled Phase 2 Study to Evaluate the Safety and Efficacy of T89 in Prevention and Treatment of Acute Mountain Sickness During Rapid Ascent, Tasly Pharmaceutical, 2017-2021
- Prevention of cerebral injury in pediatric diabetic ketoacidosis, American Diabetes Association, 2017-2021
- Testosterone's role in sex-specific outcomes after early anesthesia, NIH, 2015-2021
- Volatile anesthetic alteration of neural precursor cell cycle and fate decisions, NIH, 2010-2015
Publications (41)
Top publication keywords:
Methyl EthersSpatial MemoryAnesthesiaRats, Sprague-DawleyMaze LearningPropofolMemory DisordersNeurotoxicity SyndromesSymportersAnesthetics, InhalationIsofluraneResearch ReportSolute Carrier Family 12, Member 2NeuroprotectionAnesthetics
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A Spatial Memory Deficit in Male But Not Female Rats After Neonatal Diazepam Exposure: A New Model for Developmental Sedative Neurotoxicity.
Anesthesia and analgesia 2024 Chinn GA, Cummins MH, Sall JW -
A Randomized Phase 2 Study to Evaluate Efficacy and Safety of AR36 for Prevention of Acute Mountain Sickness.
Wilderness & environmental medicine 2023 Schober A, Chinn G, Eichbaum Y, Dudley M, Sall JW, University of California San Francisco AR36 working group -
The Effect of Route of Administration and Vehicle on the Pharmacokinetics of THC and CBD in Adult, Neonate, and Breastfed Sprague-Dawley Rats.
Cannabis and cannabinoid research 2023 Soni I, Chinn GA, Halifax JC, Hellman J, Lynch KL, Sall JW -
Anesthesia-induced Recognition Deficit Is Improved in Postnatally Gonadectomized Male Rats.
Journal of neurosurgical anesthesiology 2021 Sasaki Russell JM, Hagelstein M, Lee BH, Sall JW -
Testosterone is Sufficient to Impart Susceptibility to Isoflurane Neurotoxicity in Female Neonatal Rats.
Journal of neurosurgical anesthesiology 2021 Chinn GA, Duong K, Horovitz TR, Sasaki Russell JM, Sall JW
Show all (36 more) Hide
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Androgenic Modulation of the Chloride Transporter NKCC1 Contributes to Age-dependent Isoflurane Neurotoxicity in Male Rats.
Anesthesiology 2020 Chinn GA, Sasaki Russell JM, Yabut NA, Maharjan D, Sall JW -
Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group.
British journal of anaesthesia 2020 Chinn GA, Pearn ML, Vutskits L, Mintz CD, Loepke AW, Lee JJ, Chen J, Bosnjak ZJ, Brambrink AM, Jevtovic-Todorovic V, Sun LS, Sall JW -
Voluntary Exercise Rescues the Spatial Memory Deficit Associated With Early Life Isoflurane Exposure in Male Rats.
Anesthesia and analgesia 2019 Chinn GA, Sasaki Russell JM, Banh ET, Lee SC, Sall JW -
Female rats are more vulnerable to lasting cognitive impairment after isoflurane exposure on postnatal day 4 than 7.
British journal of anaesthesia 2019 Sasaki Russell JM, Chinn GA, Maharjan D, Eichbaum Y, Sall JW -
Targeting Microglia: A New Avenue for Anesthesia Neuroprotection after Brain Injury?
Anesthesiology 2018 Vutskits L, Sall JW -
Increased Cytokines at High Altitude: Lack of Effect of Ibuprofen on Acute Mountain Sickness, Physiological Variables, or Cytokine Levels.
High altitude medicine & biology 2018 Lundeberg J, Feiner JR, Schober A, Sall JW, Eilers H, Bickler PE -
A poisoned chalice: the heritage of parental anaesthesia exposure.
British journal of anaesthesia 2018 Vutskits L, Sall JW, Jevtovic-Todorovic V -
Resection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies.
Journal of neurosurgery 2017 Southwell DG, Birk HS, Han SJ, Li J, Sall JW, Berger MS -
Reproducibility of science and developmental anaesthesia neurotoxicity: a tale of two cities.
British journal of anaesthesia 2017 Vutskits L, Sall JW -
Histological and cognitive alterations in adult diabetic rats following an episode of juvenile diabetic ketoacidosis: Evidence of permanent cerebral injury.
Neuroscience letters 2017 Glaser N, Sasaki-Russell J, Cohen M, Little C, O'Donnell M, Sall J -
Anesthesia Kills Brain Cells, but What Does It Mean?
Anesthesiology 2016 Sall JW -
Is a short anesthetic exposure in children safe? Time will tell: a focused commentary of the GAS and PANDA trials.
Annals of translational medicine 2016 Chinn GA, Sasaki Russell JM, Sall JW -
Summary of the Update Session on Clinical Neurotoxicity Studies.
Journal of neurosurgical anesthesiology 2016 Pinyavat T, Warner DO, Flick RP, McCann ME, Andropoulos DB, Hu D, Sall JW, Spann MN, Ing C -
Early exposure to volatile anesthetics impairs long-term associative learning and recognition memory.
PloS one 2014 Lee BH, Chan JT, Hazarika O, Vutskits L, Sall JW -
Effect of combining anesthetics in neonates on long-term cognitive function.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2014 Lee BH, Hazarika OD, Quitoriano GR, Lin N, Leong J, Brosnan H, Chan JT, May LD, Yu D, Alkhamisi A, Stratmann G, Sall JW -
Effect of general anesthesia in infancy on long-term recognition memory in humans and rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 Stratmann G, Lee J, Sall JW, Lee BH, Alvi RS, Shih J, Rowe AM, Ramage TM, Chang FL, Alexander TG, Lempert DK, Lin N, Siu KH, Elphick SA, Wong A, Schnair CI, Vu AF, Chan JT, Zai H, Wong MK, Anthony AM,… -
Isoflurane exposure in newborn rats induces long-term cognitive dysfunction in males but not females.
Neuropharmacology 2014 Lee BH, Chan JT, Kraeva E, Peterson K, Sall JW -
Accuracy of the Lifebox pulse oximeter during hypoxia in healthy volunteers.
Anaesthesia 2013 Dubowitz G, Breyer K, Lipnick M, Sall JW, Feiner J, Ikeda K, MacLeod DB, Bickler PE -
Biphasic change of progenitor proliferation in dentate gyrus after single dose of isoflurane in young adult rats.
Journal of neurosurgical anesthesiology 2013 Lin N, Moon TS, Stratmann G, Sall JW -
Technical communication: stability of propofol in polystyrene-based tissue culture plates.
Anesthesia and analgesia 2013 Sall JW, Leong J -
Distinct long-term neurocognitive outcomes after equipotent sevoflurane or isoflurane anaesthesia in immature rats.
British journal of anaesthesia 2013 Ramage TM, Chang FL, Shih J, Alvi RS, Quitoriano GR, Rau V, Barbour KC, Elphick SA, Kong CL, Tantoco NK, Ben-Tzur D, Kang H, McCreery MS, Huang P, Park A, Uy J, Rossi MJ, Zhao C, Di Geronimo RT, … -
Accuracy of carboxyhemoglobin detection by pulse CO-oximetry during hypoxemia.
Anesthesia and analgesia 2013 Feiner JR, Rollins MD, Sall JW, Eilers H, Au P, Bickler PE -
Propofol at clinically relevant concentrations increases neuronal differentiation but is not toxic to hippocampal neural precursor cells in vitro.
Anesthesiology 2012 Sall JW, Stratmann G, Leong J, Woodward E, Bickler PE -
Delayed environmental enrichment reverses sevoflurane-induced memory impairment in rats.
Anesthesiology 2012 Shih J, May LD, Gonzalez HE, Lee EW, Alvi RS, Sall JW, Rau V, Bickler PE, Lalchandani GR, Yusupova M, Woodward E, Kang H, Wilk AJ, Carlston CM, Mendoza MV, Guggenheim JN, Schaefer M, Rowe AM, … -
Beyond anesthetic properties: the effects of isoflurane on brain cell death, neurogenesis, and long-term neurocognitive function.
Anesthesia and analgesia 2010 Stratmann G, Sall JW, May LD, Loepke AW, Lee MT -
Erythropoietin promotes hippocampal neurogenesis in in vitro models of neonatal stroke.
Neurobiology of disease 2010 Osredkar D, Sall JW, Bickler PE, Ferriero DM -
Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats.
Anesthesiology 2010 Stratmann G, Sall JW, Bell JS, Alvi RS, May Ld, Ku B, Dowlatshahi M, Dai R, Bickler PE, Russell I, Lee MT, Hrubos MW, Chiu C -
Increasing the duration of isoflurane anesthesia decreases the minimum alveolar anesthetic concentration in 7-day-old but not in 60-day-old rats.
Anesthesia and analgesia 2009 Stratmann G, Sall JW, Eger EI, Laster MJ, Bell JS, May LD, Eilers H, Krause M, Heusen Fv, Gonzalez HE -
Effect of hypercarbia and isoflurane on brain cell death and neurocognitive dysfunction in 7-day-old rats.
Anesthesiology 2009 Stratmann G, May LD, Sall JW, Alvi RS, Bell JS, Ormerod BK, Rau V, Hilton JF, Dai R, Lee MT, Visrodia KH, Ku B, Zusmer EJ, Guggenheim J, Firouzian A -
Isoflurane differentially affects neurogenesis and long-term neurocognitive function in 60-day-old and 7-day-old rats.
Anesthesiology 2009 Stratmann G, Sall JW, May LD, Bell JS, Magnusson KR, Rau V, Visrodia KH, Alvi RS, Ku B, Lee MT, Dai R -
Isoflurane inhibits growth but does not cause cell death in hippocampal neural precursor cells grown in culture.
Anesthesiology 2009 Sall JW, Stratmann G, Leong J, McKleroy W, Mason D, Shenoy S, Pleasure SJ, Bickler PE -
Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial cells.
Experimental eye research 2004 Sall JW, Klisovic DD, O'Dorisio MS, Katz SE -
Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study.
Investigative ophthalmology & visual science 2001 Klisovic DD, O'Dorisio MS, Katz SE, Sall JW, Balster D, O'Dorisio TM, Craig E, Lubow M -
Octreotide: The Next Decade
Biology of Neuroendocrine Tumors 1999 Sall JW, O'Dorisio MS, O'Dorisio TM -
Flight-muscle polymorphism in the cricket Gryllus firmus: muscle characteristics and their influence on the evolution of flightlessness.
Physiological zoology 1997 Zera AJ, Sall J, Grudzinski K -
Arch Insect Biochem Physiol
Artificial selection on JHE activity in Gryllus assimilis: nature of activity differences between lines and effect on JH binding and metabolism 1996 Zera AJ, Sall J, Schwartz R