Jeffrey Critchfield, MD
Professor
Medicine
School of Medicine

In the initial stages of my career, I focused on the basic science of T-lymphocyte regulation in laboratories at the NIH and UCSF. I then transitioned to a faculty position at the General, where I held leadership roles with trainees, faculty, and SFDPH staff centered on improving the care of hospitalized patients across the care continuum and into the community. During this time, I served as Chief of Staff for the Medical Staff, Medical Director of Risk Management, Chief Medical Experience Officer, and the founding Chief of the Division of Hospital Medicine.

In 2025, I accepted the role of Vice-Dean, UCSF School of Medicine at the General. The Vice-Dean’s office is at the center of UCSF’s partnership with the City and County of San Francisco initiated in 1873. I cherish our 150+ year collaboration between a premier academic institution and an iconic public institution, a partnership heralded across the USA and the globe. We have 3,000 UCSF faculty and staff working at the General. We host trainees from all four UCSF Professional Schools, with nearly a third of UCSF’s learners on our campus each day. I have an abiding belief in the ability of the collective to bring forward spirit and action, uplifting patients, their loved ones, and the people here who partner with them.

Education:

• MD, University of California, San Francisco, CA, 1988-1994
• BAS, Classics, Biology, Stanford University, Palo Alto, CA, 1983-1987

Training:

• Internship, Internal Medicine, University of California, San Francisco, CA, 1994-1995
• Residency, Internal Medicine, University of California, San Francisco, CA, 1995-1996
• Fellowship, Rheumatology, University of California, San Francisco, CA 1996-1997
• Chief Residency, Internal Medicine, University of California, San Francisco, CA, 1997-1998
• Fellowship, Rheumatology, University of California, San Francisco, CA, 1998-1999
• Post-doc, Rheumatology University of California, San Francisco, CA 1999-2001

Certification:

• Medical License, Medical Board of California, #A60018, 1996
• Internal Medicine, Recertified, 2012, participant in Longitudinal Knowledge Assessment

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• Diagnostic Scheming.
  Journal of general internal medicine 2015 Martin M, Sedighi Manesh R, Henderson MC, Critchfield JM
• Functional disability in late-middle-aged and older adults admitted to a safety-net hospital.
  Journal of the American Geriatrics Society 2014 Brown RT, Pierluissi E, Guzman D, Kessell ER, Goldman LE, Sarkar U, Schneidermann M, Critchfield JM, Kushel MB
• Support from hospital to home for elders: a randomized trial.
  Annals of internal medicine 2014 Goldman LE, Sarkar U, Kessell E, Guzman D, Schneidermann M, Pierluissi E, Walter B, Vittinghoff E, Critchfield J, Kushel M
• "Missing pieces"--functional, social, and environmental barriers to recovery for vulnerable older adults transitioning from hospital to home.
  Journal of the American Geriatrics Society 2014 Greysen SR, Hoi-Cheung D, Garcia V, Kessell E, Sarkar U, Goldman L, Schneidermann M, Critchfield J, Pierluissi E, Kushel M
• Failure of atorvastatin to modulate CSF HIV-1 infection: results of a pilot study.
  Neurology 2008 Probasco JC, Spudich SS, Critchfield J, Lee E, Lollo N, Deeks SG, Price RW
• Interpretation of serologic tests in an HIV-infected patient with kidney disease.
  Nature clinical practice. Nephrology 2006 Hernandez GT, Critchfield JM, Rodriguez RA
• Reducing unnecessary inpatient laboratory testing in a teaching hospital.
  American journal of clinical pathology 2006 May TA, Clancy M, Critchfield J, Ebeling F, Enriquez A, Gallagher C, Genevro J, Kloo J, Lewis P, Smith R, Ng VL
• Treating the latent reservoir of HIV.
  The AIDS reader 2004 Critchfield JM, Deeks SG
• Intravenous antigen administration as a therapy for autoimmune demyelinating disease
  Annals of Neurology 1996 Racke, M; Critchfield, JM; Quigley, L; McFarland, H.; Lenardo, MJ
• Antigen-Induced Programmed T Cell Death as a New Approach to Immune Therapy
  Clinical Immunology and Immunopathology 1995 Critchfield, JM; Lenardo, MJ
• Parameters controlling the programmed death of mature mouse T lymphocytes in high-dose suppression
  Cellular Immunology 1995 Jeffrey M. Critchfield Juan Carlos Zúñiga-Pflücker Michael Lenardo
• T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis
  Science 1994 J M Critchfield, M K Racke, J C Zúñiga-Pflücker, B Cannella, C S Raine, J Goverman, M J Lenardo