Jay Conrad, PhD
Associate Professor
Institute for Neurodegenerative Diseases
School of Medicine

Publications (8)

Top publication keywords:
Oxidation-ReductionHydrocarbons, FluorinatedIndolesCatalysisLightLignansMethylationAldehydesPhotochemical ProcessesNitrilesSolventsPhosphatesMesylatesIridiumLactones

• Model of P-Glycoprotein Ligand Binding and Validation with Efflux Substrate Matched Pairs.
  Journal of medicinal chemistry 2024 Conrad J, Paras NA, Vaz RJ
• Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics.
  Nature machine intelligence 2022 Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ
• Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.
  Organic letters 2021 Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J
• Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles.
  ACS omega 2021 Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J
• Selectivity in the Addition of Electron Deficient Radicals to the C2 Position of Indoles.
  European journal of organic chemistry 2020 Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J
• Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.
  ACS medicinal chemistry letters 2020 Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras…
• Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism.
  The Journal of organic chemistry 2018 O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J
• Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes.
  Angewandte Chemie (International ed. in English) 2015 Welin ER, Warkentin AA, Conrad JC, MacMillan DW