Jason Smith, MD
Professor
Surgery
School of Medicine
jason.smith2@ucsf.edu 415-353-1606
Dr. Jason W. Smith is a cardiac and transplant surgeon who specializes in heart transplantation and the use of mechanical circulatory support, such as artificial heart pumps and left ventricular assist devices.
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He has expertise in complex cardiac procedures that include mitral valve repair and replacement, aortic valve surgery, transcatheter aortic valve procedures (minimally invasive techniques to replace a failing valve), surgeries to treat the ascending aorta and aortic arch, treatment of endocarditis (infections of the heart's inner lining), operations to correct atrial fibrillation (irregular and often rapid heartbeats), and sternal repair and reconstruction. He also manages extracorporeal membrane oxygenation (ECMO), which supports the heart and lungs by using a machine to oxygenate blood outside of the body. He is the surgical director of UCSF's heart transplantation and mechanical circulatory support programs.
Smith has been active in a national effort to increase access to heart transplantation by improving the use of donor organs. He served as a primary investigator for a nationwide clinical trial on donation after cardiac death.
Smith earned his medical degree from the Stritch School of Medicine at Loyola University Chicago, then completed a residency in general surgery and a fellowship in cardiothoracic surgery at Loyola University Medical Center. He completed a fellowship in heart and lung transplantation at Stanford Medicine. Upon completing his training, he joined the surgical faculty at the University of Washington. Prior to joining UCSF, he served as surgical director of transplant and mechanical circulatory support at the University of Wisconsin – Madison.
Smith serves on the membership and professional standards committee of the national Organ Procurement and Transplantation Network. He frequently makes presentations on issues related to organ transplantation and utilization and belongs to numerous professional and honorary societies. He is a San Francisco native.
Education & Training
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- Heart and Lung Transplant and Mechanical Circulatory Support Stanford University Hospital and Clinics 06/2012
- Cardiothoracic Surgery Loyola University Medical Center 06/2011
- General Surgery Loyola University Medical Center 06/2009
- Research Fellowship Loyola University Medical Center, Burn Shock Trauma Center 06/2005
- MD Medicine Loyola University Medical School 06/2002
- BA University Scholar Baylor University 12/1993
Interests
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- Heart Transplantation
- Donor Organ Utilization
- Organ Donation after Cardiopulmonary determination
- ECMO
- Left Ventricular Assist Devices
- Normothermic Regional Perfusion
- Ex Vivo Organ Perfusion
- Total Artificial Heart
- Advanced Heart Failure
Publications (46)
Top publication keywords:
Heart FailureTissue DonorsAbdominal InjuriesSocieties, MedicalCardiologyHeart-Assist DevicesPeritoneal DialysisHLA AntigensOrgan PreservationShock, HemorrhagicHeart TransplantationSepsisEndocarditisAbdominal CavityTissue and Organ Procurement
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Six Square Miles of Urban America: Association Between Firearm Discharge, Injury, and Fatality.
Journal of the American College of Surgeons 2024 Risinger WB, Uma CV, Benns MV, Ruther MH, Nash NA, Bozeman MC, Coleman JJ, Smith JW, Harbrecht BG, Miller KR -
Phase I clinical trial of the feasibility and safety of direct peritoneal resuscitation in liver transplantation.
American journal of surgery 2024 Rodriguez IE, Asher ZP, Klingenberg K, Wright FL, Nydam TL, Adams MA, Bababekov YJ, Peltz E, Smith JW, Saben JL, Kennealey P, Pomposelli JJ, Pomfret EA, Moore HB -
2024 EAST Presidential Address: One Day.
The journal of trauma and acute care surgery 2024 Smith JW -
Distance to Burn Center Does Not Impact Long-term Anxiety and Depression Risk Following Burn Injury.
Journal of burn care & research : official publication of the American Burn Association 2024 Risinger WB, Dye CN, Thompson SK, Uma CV, Keeven DD, Nash NA, Smith JW, Bozeman MC -
Author reply: "What do we mean by source control and what are we trying to accomplish with an open abdomen in severe complicated intra-abdominal sepsis?"
The journal of trauma and acute care surgery 2024 Risinger WB, Smith JW
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Applying the antecedent, behaviour, and consequence taxonomy to unintentional firearm injury as determined by a collaborative firearm injury database.
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention 2024 Risinger WB, Nickols AK, Harris AN, Benns MV, Nash NA, Bozeman MC, Pera SJ, Coleman JC, Franklin GA, Smith JW, Harbrecht BG, Miller KR -
Increasing Utilization of Extended Criteria Donor Hearts for Transplantation: The OCS Heart EXPAND Trial.
JACC. Heart failure 2024 Schroder JN, Patel CB, DeVore AD, Casalinova S, Koomalsingh KJ, Shah AS, Anyanwu AC, D'Alessandro DA, Mudy K, Sun B, Strueber M, Khaghani A, Shudo Y, Esmailian F, Liao K, Pagani FD, Silvestry S, Wang … -
A Decade of Analysis of Unplanned Extubation Etiology in Trauma Patients Including the Impact of the COVID Pandemic.
Respiratory care 2023 Harbrecht BG, Miller KR, Egger ME, Nash NA, Doan R, Georgel J, Franklin GA, Smith JW, Bozeman MC, Benns MV -
Expanding the Donation After Circulatory Death Transplant Pool in the United States.
The Annals of thoracic surgery 2023 Fiedler A, Miller PN, Smith JW -
Plasma resuscitation improves and restores intestinal microcirculatory physiology following haemorrhagic shock.
Vox sanguinis 2023 Schucht JE, Harbrecht BG, Bond LM, Risinger WB, Matheson PJ, Smith JW -
Damage control surgery in emergency general surgery: What you need to know.
The journal of trauma and acute care surgery 2023 Risinger WB, Smith JW -
Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study.
Trauma surgery & acute care open 2023 Ziesmann M, Byerly S, Yeh DD, Boltz M, Gelbard R, Haut ER, Smith JW, Stein DM, Zarzaur BL, Bensard DD, Biffl WL, Boyd A, Brommeland T, Cothren Burlew C, Fabian T, Lauerman M, Leichtle S, Moore EE, … -
Transplantation Outcomes with Donor Hearts after Circulatory Death.
The New England journal of medicine 2023 Schroder JN, Patel CB, DeVore AD, Bryner BS, Casalinova S, Shah A, Smith JW, Fiedler AG, Daneshmand M, Silvestry S, Geirsson A, Pretorius V, Joyce DL, Um JY, Esmailian F, Takeda K, Mudy K, Shudo Y, … -
Comment on: Detection and management of HLA sensitization in candidates for adult heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023 Fiedler AG, Klein L, DeMarco T, Kouretas P, Smith JW -
Establishing a core outcomes set for massive transfusion: An Eastern Association for the Surgery of Trauma modified Delphi method consensus study.
The journal of trauma and acute care surgery 2023 Gelbard RB, Nahmias J, Byerly S, Ziesmann M, Stein D, Haut ER, Smith JW, Boltz M, Zarzaur B, Callum J, Cotton BA, Cripps M, Gunter OL, Holcomb JB, Kerby J, Kornblith LZ, Moore EE, Riojas CM, Schreiber… -
Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant.
Innovations (Philadelphia, Pa.) 2022 Wisneski A, Smith JW, Nguyen TC, Fiedler AG -
Effect of Plasma Resuscitation with Adjunctive Peritoneal Resuscitation on Hepatic Blood Flow and End-Organ Damage after Hemorrhagic Shock.
Journal of the American College of Surgeons 2022 Smith JW, Schucht JE, Harbrecht BG, Bond LM, Matheson PJ -
Direct Peritoneal Resuscitation for Trauma.
Advances in surgery 2022 Pera SJ, Schucht J, Smith JW -
A new pandemic and an old epidemic: The impact of COVID-19 and gun violence as measured by years of potential life lost in a US city.
Surgery 2022 Risinger WB, Pera SJ, Bhutiani N, Ruther M, Harbrecht BG, Smith JW, Benns MV, Miller KR -
Normothermic regional perfusion surgical technique for the procurement of cardiac donors after circulatory death.
JTCVS techniques 2022 Fiedler AG, DeVries S, Czekajlo C, Smith JW -
Unconventional use of total artificial heart in a patient with severe, destructive prosthetic valve endocarditis.
Journal of cardiac surgery 2021 Johnstad C, Bomareddi S, Hermsen JL, Smith JW, Fiedler AG -
Survival after orthotopic heart transplantation in patients with BMI > = 35 with and without diabetes.
Clinical transplantation 2021 Fiedler AG, Stalter L, Marka N, Dhingra R, Hermsen JL, Smith JW -
Left ventricular assist device implantation by bi-thoracotomy technique: A single-center perspective.
Journal of cardiac surgery 2021 Stoeckl EM, Smith JW, Dhingra R, Fiedler AG -
Risk factors and outcomes for delayed kidney graft function in simultaneous heart and kidney transplant recipients: A UNOS/OPTN database analysis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Parajuli S, Karim AS, Muth BL, Leverson GE, Yang Q, Dhingra R, Smith JW, Foley DP, Mandelbrot DA -
Successful heart transplantation in a patient who recovered from COVID-19.
Journal of cardiac surgery 2021 Johnstad CM, Murray D, Dhingra R, Smith JW, Fiedler AG -
Orthotopic Heart Transplant: How I Teach It.
The Annals of thoracic surgery 2020 Fiedler AG, Hermsen JL, Bommareddi S, Smith JW -
Amiodarone Use Prior to Cardiac Transplant Impacts Early Post-Transplant Survival.
Cardiovascular drugs and therapy 2020 Allana SS, Rajput FA, Smith JW, Lozonschi L, Liou JI, Johnson M, Kohmoto T, Dhingra R -
2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.
Journal of cardiac failure 2020 Writing Committee Members, Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin C, Meehan K, … -
2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.
Journal of the American College of Cardiology 2020 Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin CM, Meehan K, Morrow DA, Schlendorf K, Smith … -
Long-term discontinuation of warfarin in a patient with HeartMate 3 left ventricular assist device without complication.
Journal of cardiac surgery 2019 Fiedler AG, Hermsen JL, Smith JW, Dhingra R -
Small Left Ventricular Size Is an Independent Risk Factor for Ventricular Assist Device Thrombosis.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2019 Chivukula VK, Beckman JA, Prisco AR, Lin S, Dardas TF, Cheng RK, Farris SD, Smith JW, Mokadam NA, Mahr C, Aliseda A -
Left Ventricular Assist Device Inflow Cannula Angle and Thrombosis Risk.
Circulation. Heart failure 2018 Chivukula VK, Beckman JA, Prisco AR, Dardas T, Lin S, Smith JW, Mokadam NA, Aliseda A, Mahr C -
Dilemmas in Dual Disease: Complexity and Futility in Prosthetic Valve Endocarditis and Substance Use Disorder.
The American journal of bioethics : AJOB 2018 Kirkpatrick JN, Smith JW -
Invited Commentary.
The Annals of thoracic surgery 2017 Smith JW, Mokadam NA -
Pulmonary function tests do not predict mortality in patients undergoing continuous-flow left ventricular assist device implantation.
The Journal of thoracic and cardiovascular surgery 2017 Bedzra EKS, Dardas TF, Cheng RK, Pal JD, Mahr C, Smith JW, Shively K, Masri SC, Levy WC, Mokadam NA -
The Benefit of Donor-Recipient Matching for Patients Undergoing Heart Transplantation.
Journal of the American College of Cardiology 2017 Nguyen VP, Mahr C, Mokadam NA, Pal J, Smith JW, Dardas TF -
Outflow Graft Obstruction Treated With Transcatheter Management: A Novel Therapy for a New Diagnosis.
The Annals of thoracic surgery 2017 Bhamidipati CM, Pal JD, Jones TK, McCabe JM, Reisman M, Smith JW, Mahr C, Mokadam NA -
Successful Repair of Acute Type A Aortic Dissection 15 Years Following Bilateral Lung Transplantation.
Journal of cardiac surgery 2015 Hermsen JL, Madathil R, Berfield KS, Li K, Smith JW, Mulligan MS -
Endovascular Repair for Type A Aortic Dissection After Transcatheter Aortic Valve Replacement With a Medtronic CoreValve.
The Annals of thoracic surgery 2015 Berfield KK, Sweet MP, McCabe JM, Reisman M, Mackensen GB, Mokadam NA, Dean LS, Smith JW -
Systematic donor selection review process improves cardiac transplant volumes and outcomes.
The Journal of thoracic and cardiovascular surgery 2015 Smith JW, O'Brien KD, Dardas T, Pal JD, Fishbein DP, Levy WC, Mahr C, Masri SC, Cheng RK, Stempien-Otero A, Mokadam NA -
Periportal fibrosis without cirrhosis does not affect outcomes after continuous flow ventricular assist device implantation.
The Journal of thoracic and cardiovascular surgery 2015 Sargent JE, Dardas TF, Smith JW, Pal JD, Cheng RK, Masri SC, Shively KR, Colyer LM, Mahr C, Mokadam NA -
Late Surgical Bleeding Following Total Artificial Heart Implantation.
Journal of cardiac surgery 2015 Hermsen JL, Smith JW, Pal JD, Mahr C, Masri SC, Dardas TF, Cheng RK, Mokadam NA -
Self-administration education and polypharmacy in mechanical circulatory support patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2013 Hermsen JL, Smith JW, Mokadam NA -
The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma.
American journal of surgery 2009 Smith JW, Moreira J, Abood G, Aranha GV, Nagda S, Wagner RH, Shoup M -
Immunologic responses to critical injury and sepsis.
Journal of intensive care medicine 2006 Smith JW, Gamelli RL, Jones SB, Shankar R -
New perspectives for a new century: implications of pathogen responses for the future of antimicrobial therapy.
Journal of burn care & research : official publication of the American Burn Association 2006 Melstrom KA, Smith JW, Gamelli RL, Shankar R