Jason Pomerantz, MD
Professor
Surgery
School of Medicine

He is one of two craniofacial surgeons at UCSF and the sole craniofacial surgeon providing care of facial trauma and craniofacial reconstruction at Zuckerberg San Francisco General Hospital. Additionally, Dr. Pomerantz is one of four surgeons at UCSF performing facial gender affirmation surgery, and the only surgeon to perform these procedures at ZSFGH, where he led and performed the first series of facial gender affirmation operations for an underserved population at a county hospital in the United States. He also is Co-Chair of the Department of Surgery Research Committee at UCSF, overseeing the department research activities focused on student and resident scholarly work and Director of Pomerantz Laboratory. The Pomerantz Laboratory studies basic and translational aspects of tissue regeneration. Their research program is closely related to regenerative medicine. With foundations in muscle and cancer biology, they are investigating regenerative mechanisms including stem cell function and de-differentiation. By employing model organisms such as zebrafish and mouse and extending discoveries to human cells and tissues, they aim to gain fundamental insight that can be translated into clinical advances, most notably solving the structural and reconstructive problems of the limbs, face, and head.

• Loss of transcriptional heterogeneity in aged human muscle stem cells.
  PloS one 2023 Barruet E, Striedinger K, Marangoni P, Pomerantz JH
• Long-pulsed neodymium-doped yttrium aluminum garnet for hair reduction in pediatric microtia repair.
  Pediatric dermatology 2023 Braun M, Pomerantz JH, Hoffman WY, Mathes EF
• Patient-Reported Outcomes in Gender-Affirming Facial Surgery: Recommendations from a Multidisciplinary Gender Health Panel.
  Facial plastic surgery & aesthetic medicine 2023 Zebolsky AL, Gulati A, Badiee RK, Pardo ST, Deutsch MB, Knott PD, Park AM, Pomerantz JH, Hoffman WY, Seth R
• Gender-Affirming Facial Feminization Surgery at a Public, Safety-Net Hospital: A Single-Center Early Experience.
  The Journal of craniofacial surgery 2022 Alcon A, Badiee RK, Barnes LL, Pardo ST, Zevin B, Pomerantz JH
• Racial and Socioeconomic Disparities in Prompt Craniosynostosis Workup and Treatment.
  The Journal of craniofacial surgery 2022 Badiee RK, Maru J, Yang SC, Alcon A, Rosenbluth G, Pomerantz JH
• Robin Sequence: 5-Year Speech Outcomes-A Case-Control Study.
  Plastic and reconstructive surgery 2022 Logjes RJH, Breugem CC, Pomerantz JH
• Superior Long-term Appearance of Strip Craniectomy Compared with Cranial Vault Reconstruction in Metopic Craniosynostosis.
  Plastic and reconstructive surgery. Global open 2022 Badiee RK, Popowitz E, Mark IT, Alcon A, Hwang J, Rorison E, Auguste KI, Hoffman WY, Sun PP, Pomerantz JH
• Disparities in Timing of Alveolar Bone Grafting and Dental Reconstruction in Patients With Clefts.
  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2022 Badiee RK, Yang SC, Alcon A, Weeks AC, Rosenbluth G, Pomerantz JH
• Modeling the ACVR1R206H mutation in human skeletal muscle stem cells.
  eLife 2021 Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, Pomerantz JH, Hsiao EC
• Comparing Long-term Outcomes of Open Cranial Vault Reconstruction and Minimally Invasive Strip Craniectomy in Metopic Craniosynostosis.
  Plastic & Reconstructive Surgery Global Open 2021 Ryan Badiee, Emma Popowitz, Ian Mark, Joan Hwang, Eve Rorison, Kurtis Auguste, William Y. Hoffman, Peter P. Sun, Jason H. Pomerantz
• An Early Experience with Gender-affirming Facial Feminization Surgery at a Public, Safety-net Hospital.
  Plastic & Reconstructive Surgery Global Open 2021 Andre Alcon, Ryan K. Badiee, Laura L. Barnes, Seth T. Pardo, Barry Zevin, Jason H. Pomerantz
• Comparing Long-term Outcomes of Open Cranial Vault Reconstruction and Minimally Invasive Strip Craniectomy in Metopic Craniosynostosis
  Plastic and Reconstructive Surgery - Global Open. 2021 Badiee RK, Popowitz E, Mark I, Hwang J, Rorison E, Auguste KI, Hoffman WY, Sun PP, and Pomerantz JH.
• Purification and preservation of satellite cells from human skeletal muscle.
  STAR protocols 2021 Striedinger K, Barruet E, Pomerantz JH
• Long-term Speech Outcomes of Cleft Palate Repair in Robin Sequence versus Isolated Cleft Palate.
  Plastic and reconstructive surgery. Global open 2021 Logjes RJH, Upton S, Mendelsohn BA, Badiee RK, Breugem CC, Hoffman WY, Pomerantz JH
• ACVR1R206H increases osteogenic/ECM gene expression and impairs myofiber formation in human skeletal muscle stem cells
  bioRxiv 2021 Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, and Pomerantz JH.
• Facial Feminization Surgery: Key CT Findings for Preoperative Planning and Postoperative Evaluation.
  AJR. American journal of roentgenology 2020 Callen AL, Badiee RK, Phelps A, Potigailo V, Wang E, Lee S, Talbott J, Glastonbury C, Pomerantz JH, Narvid J
• Facial Feminization Surgery: Key CT Findings for Preoperative Planning and Postoperative Evaluation.
  AJR. American journal of roentgenology 2020 Callen AL, Badiee RK, Phelps A, Potigailo V, Wang E, Lee S, Talbott J, Glastonbury C, Pomerantz JH, Narvid J
• Satellite cell activation and retention of muscle regenerative potential after long-term denervation.
  Stem cells (Dayton, Ohio) 2020 Wong A, Garcia SM, Tamaki S, Striedinger K, Barruet E, Hansen SL, Young DM, Pomerantz JH
• Transitioning Multidisciplinary Craniofacial Care to Telehealth during the COVID-19 Pandemic: A Single Center Experience.
  Plastic and reconstructive surgery. Global open 2020 Badiee RK, Willsher H, Rorison E, Langham M, Donnelly A, Rosenbluth G, Pomerantz JH
• Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart.
  Genes 2020 Lee S, Hesse R, Tamaki S, Garland C, Pomerantz JH
• MON-710 ACVR1 Activation in Primary and iPS-Derived Human Skeletal Muscle Stem Cells Impairs Myogenic Transcriptional Signature and Function.
  Journal of the Endocrine Society 2020 Emilie Barruet, Steven Garcia, Stanley Tamaki, Blanca M Morales, Jake Wu, Tania Moody, Jason H Pomerantz, Edward Chiaming Hsiao
• Functionally heterogeneous human satellite cells identified by single cell RNA sequencing.
  eLife 2020 Barruet E, Garcia SM, Striedinger K, Wu J, Lee S, Byrnes L, Wong A, Xuefeng S, Tamaki S, Brack AS, Pomerantz JH
• From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells.
  Current opinion in cell biology 2020 Trentesaux C, Striedinger K, Pomerantz JH, Klein OD
• TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia.
  Molecular genetics & genomic medicine 2019 Balkin DM, Poranki M, Forester CM, Dorsey MJ, Slavotinek A, Pomerantz JH
• A Cross-sectional Study of the Association between Homelessness and Facial Fractures.
  Plastic and reconstructive surgery. Global open 2019 Nguyen AB, Grimes B, Neuhaus J, Pomerantz JH
• Case Report of Floating-Harbor Syndrome With Bilateral Cleft Lip.
  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2019 Ko J, Pomerantz JH, Perry H, Shieh JT, Slavotinek AM, Oberoi S, Klein OD
• The Role of Muscle Stem Cells in Regeneration and Recovery after Denervation: A Review.
  Plastic and reconstructive surgery 2019 Wong A, Pomerantz JH
• Muscle stem cell activation in a mouse model of rotator cuff injury.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2018 Davies MR, Garcia S, Tamaki S, Liu X, Lee S, Jose A, Pomerantz JH, Feeley BT
• High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells.
  Stem cell reports 2018 Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH
• Recalcitrant Invasive Skin Cancer of the Scalp: Combined Extirpation and Microsurgical Reconstruction Without Cranioplasty.
  The Journal of craniofacial surgery 2017 Cho GJ, Wang F, Garcia SM, Viner J, Hoffman WY, McDermott MW, Pomerantz JH
• EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells.
  Stem cell reports 2017 Niethamer TK, Larson AR, O'Neill AK, Bershteyn M, Hsiao EC, Klein OD, Pomerantz JH, Bush JO
• Human Satellite Cell Isolation and Xenotransplantation.
  Methods in molecular biology (Clifton, N.J.) 2017 Garcia SM, Tamaki S, Xu X, Pomerantz JH
• The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration.
  eLife 2015 Hesse RG, Kouklis GK, Ahituv N, Pomerantz JH
• Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles.
  Stem cell reports 2015 Xu X, Wilschut KJ, Kouklis G, Tian H, Hesse R, Garland C, Sbitany H, Hansen S, Seth R, Knott PD, Hoffman WY, Pomerantz JH
• Bilateral Coronoidectomy by Craniofacial Approach for Hecht Syndrome-Related Trismus.
  The Journal of craniofacial surgery 2015 Balkin DM, Chen I, Oberoi S, Pomerantz JH
• Abstract 143.
  Plastic & Reconstructive Surgery 2015 Xiaoti Xu, Karlijn Wilschut, Gayle Kouklis, Hua Tian, Robert Hesse, Jason H. Pomerantz
• Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets.
  BMC biotechnology 2014 Tamaki S, Nye C, Slorach E, Scharp D, Blau HM, Whiteley PE, Pomerantz JH
• Tumor suppressors: enhancers or suppressors of regeneration?
  Development (Cambridge, England) 2013 Pomerantz JH, Blau HM
• Regenerative strategies for craniofacial disorders.
  Frontiers in physiology 2012 Garland CB, Pomerantz JH
• Re"evolutionary" regenerative medicine.
  JAMA 2010 Blau HM, Pomerantz JH
• Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice.
  Cell 2010 Sacco A, Mourkioti F, Tran R, Choi J, Llewellyn M, Kraft P, Shkreli M, Delp S, Pomerantz JH, Artandi SE, Blau HM
• Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle.
  Cell stem cell 2010 Pajcini KV, Corbel SY, Sage J, Pomerantz JH, Blau HM
• Reprogramming to a muscle fate by fusion recapitulates differentiation.
  Journal of cell science 2009 Pomerantz JH, Mukherjee S, Palermo AT, Blau HM
• Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 Palermo A, Doyonnas R, Bhutani N, Pomerantz J, Alkan O, Blau HM
• Myoblasts and macrophages share molecular components that contribute to cell-cell fusion.
  Journal of Experimental Medicine 2008 Kostin V. Pajcini, Jason H. Pomerantz, Ozan Alkan, Regis Doyonnas, Helen M. Blau
• Suture techniques for the nasal tip.
  Aesthetic surgery journal 2008 Gruber RP, Weintraub J, Pomerantz J
• Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation.
  The Journal of biological chemistry 2007 Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu BM, Harland R, Blau HM, Longaker MT
• Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons.
  Proceedings of the National Academy of Sciences of the United States of America 2007 Zhang F, Pomerantz JH, Sen G, Palermo AT, Blau HM
• A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Wehrman TS, Raab WJ, Casipit CL, Doyonnas R, Pomerantz JH, Blau HM
• 49: Plastic Surgery Research Council 2005 Clifford C. Synder, MD Award - Nuclear Cloning by Fusion of Somatic Cells
  Plastic and Reconstructive Surgery. 2006 Pomerantz JH and Blau HM (published as "APA Pomerantz, Jason MD; Pomerantz, Blau J.")
• Noggin suppression enhances osteogenesis of murine osteoblasts.
  Journal of the American College of Surgeons 2005 Derrick C. Wan, Jason Pomerantz, Randall Nacamuli, Matthew Siedhoff, Helen Blau, Michael T. Longaker
• PSEF 2005 Scientific Essay Contest D. Ralph Millard, MD Investigator Award, First Place: siRNA Mediated Noggin Suppression Enhances Osteoblast Differentiation and Mineral Deposition.
  Plastic & Reconstructive Surgery 2005 Derrick Wan, Jason H. Pomerantz, Randall P. Nacamuli, Michael T. Longaker
• Bone marrow contribution to skeletal muscle: a physiological response to stress.
  Developmental biology 2005 Palermo AT, Labarge MA, Doyonnas R, Pomerantz J, Blau HM
• Nuclear reprogramming: a key to stem cell function in regenerative medicine.
  Nature cell biology 2004 Pomerantz J, Blau HM
• Adult Bone-Marrow-Derived Stem Cells. From Brain to Brawn
  Differentiation. 2004 Blau H and Pomerantz J.
• Muscle injury: Blood to the rescue
  Experimental Hematology. 2004 Blau HM, Doyonnas R, Labarge MA, Sacco A, Palermo A, and Pomerantz J.
• Reprogramming Mechanisms: Inducing the myogenic program in non-muscle cells
  Differentiation. 2004 Pomerantz J and Blau HM.
• Essential role for oncogenic Ras in tumour maintenance.
  Nature 1999 Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N, Shen Q, O'Hagan R, Pantginis J, Zhou H, Horner JW, Cordon-Cardo C, Yancopoulos GD, DePinho RA
• Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis.
  International journal of oncology 1999 Orlow I, Rabbani F, Chin L, Pomerantz J, Ligeois N, Dudas M, Depinho R, Cordón-Cardó C
• The INK4a/ARF tumor suppressor: one gene--two products--two pathways.
  Trends in biochemical sciences 1998 Chin L, Pomerantz J, DePinho RA
• The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53.
  Cell 1998 Pomerantz J, Schreiber-Agus N, Liégeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA
• The familial melanoma gene INK4a, cooperates with activated RAS in development of melanoma: A mouse model
  Journal of Dermatological Science. 1998 Chin L, Pomerantz J, Wong M, Horner J, and DePinho R.
• Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.
  Genes & development 1997 Chin L, Pomerantz J, Polsky D, Jacobson M, Cohen C, Cordon-Cardo C, Horner JW, DePinho RA
• Mouse Models to examine the role of INK4a and RAS in malignant melanoma
  Journal Investigative Dermatology. 1997 Chin L, Pomerantz J, Liegeois N, Jacobson M, Horner J, and DePinho R.