Jason Boehme, MD
Assistant Professor
Pediatrics
School of Medicine

Education & Training

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• Fellowship Pediatric Critical Care University of California, San Francisco
• Residency School of Medicine University of California, San Francisco

Interests

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• Vascular disease
• Pulmonary Hypertension
• Pulmonary Vascular Disease
• Cellular Metabolism
• Vascular Smooth Muscle
• Congenital Heart Disease
• Lymphatic Biology
• Vascular Biology

Publications (10)

Top publication keywords:
Vascular DiseasesHemeEndothelial CellsHypoxia-Inducible Factor 1, alpha SubunitNADPH OxidasesPulmonary ArteryMuscle, Smooth, VascularLymphSheepNitric OxideLeukomalacia, PeriventricularHypoxiaMyocytes, Smooth MusclePentose Phosphate PathwayHydroxymethylglutaryl-CoA Reductase Inhibitors

• Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation.
  Nitric oxide : biology and chemistry 2023 Boehme JT, Sun X, Lu Q, Barton J, Wu X, Gong W, Raff GW, Datar SA, Wang T, Fineman JR, Black SM
• HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow.
  Scientific reports 2021 Boehme JT, Morris CJ, Chiacchia SR, Gong W, Wu KY, Kameny RJ, Raff GW, Fineman JR, Maltepe E, Datar SA
• Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease.
  Pulmonary circulation 2020 Zhu T, Chiacchia S, Kameny RJ, Garcia De Herreros A, Gong W, Raff GW, Boehme JB, Maltepe E, Lasheras JC, Black SM, Datar SA, Fineman JR
• Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling.
  American journal of respiratory cell and molecular biology 2019 Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR
• Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.
  PLoS biology 2019 Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, …

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• Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.
  PLoS biology 2018 Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, …
• Analysis of the microRNA signature driving adaptive right ventricular hypertrophy in an ovine model of congenital heart disease.
  American journal of physiology. Heart and circulatory physiology 2018 Kameny RJ, He Y, Zhu T, Gong W, Raff GW, Chapin CJ, Datar SA, Boehme JT, Hata A, Fineman JR
• KLF2-mediated disruption of PPAR-γ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow.
  American journal of physiology. Heart and circulatory physiology 2018 Morris CJ, Kameny RJ, Boehme J, Gong W, He Y, Zhu T, Maltepe E, Raff GW, Fineman JR, Datar SA
• Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation.
  American journal of physiology. Heart and circulatory physiology 2016 Boehme J, Sun X, Tormos KV, Gong W, Kellner M, Datar SA, Kameny RJ, Yuan JX, Raff GW, Fineman JR, Black SM, Maltepe E
• Spare hypoxia, spoil the child?
  The Journal of clinical investigation 2015 Boehme J, Maltepe E