Janine Lupo, PhD
Professor
Radiology
School of Medicine
Janine Lupo, PhD, is a Professor in the Surbeck Laboratory of Advanced Imaging and Neuroimaging Research Interest Group of the Department of Radiology and Biomedical Imaging. She is a member of the UCSF/UC Berkeley Graduate Group in Bioengineering, Helen Diller Family Comprehensive Cancer Center, Institute for Computational Health Sciences, and Quantitative Biosciences Institute.
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Dr. Lupo received her BSE in Bioengineering at the University of Pennsylvania, School of Engineering and Applied Science in Philadelphia before completing her PhD at the UCSF/UCB PhD Joint Graduate Group in Bioengineering. Before accepting an in residence position, Dr. Lupo was an Assistant and Associate Researcher in the Department of Radiology and Biomedical Imaging at UCSF.
Dr. Lupo’s research focuses on the development and application of novel MR imaging data acquisition, processing, and analysis techniques for the evaluation of patients with brain tumors and other neurological diseases using our research 3T and 7T whole body scanners. This includes the development of quantitative algorithms critical for processing data from advanced acquisitions for patient studies, implementation of statistical and machine learning models to relate imaging markers with biological characteristics from pathology and clinical outcome in order to both identify patients who would benefit most for a given therapy, and monitor the effects of therapy over time on tumor control, normal brain tissue structure, and cognition.
Dr. Lupo has been the Principal or Co-Principal Investigator for multiple NIH and DoD grants, as well as a co-Project leader of 2 projects within an NIH Programmatic Project Grant and Brain Tumor SPORE Grant. She has published over 75 research articles.
Expertise: Bioengineering
Specialty: Neuroimaging
Professional Interests: Magnetic resonance imaging, ultra-high field MRI, algorithm development for quantitative image analysis, imaging biomarker discovery, brain cancer, neurological diseases, evaluation of therapy, the effects of therapy on cognition, statistical modeling, and deep learning
Awards
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- Emerging Leader Award Finalist, Mark Foundation for Cancer Research, 2021
- Johnson & Johnson Women In STEM2D award in Engineering, UCSF nominee, UCSF, 2017
- RAP Family Support Award, UCSF, 2016
- Clinical Loan Repayment Program Continuation Award, National Institutes of Health, 2012
- RAP Grants Novel Clinical/Translational Methods Award, UCSF, 2012
- Radiology Symposium Poster Award, UCSF, 2011
- Neuroimaging Poster Award Nomination, ISMRM Conference, 2010
- Clinical Loan Repayment Program Award, National Institutes of Health, 2010
- Brain Tumor SPORE Career Development Award, UCSF, 2010
- Honorable Mention Poster Award, UCSF BTS Symposium, 2010
- Radiology Symposium Poster Award, UCSF, 2008
- Surbeck Scholar Award, UCSF Department of Radiology and Biomedical Imaging, 2006
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2021
- PhD Joint Graduate Program in Bioegineering University of California, Berkeley & San Francisco 2006
- BSE School of Engineering and Applied Sciences University of Pennslyvania 2001
Interests
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- 7 Tesla MRI
- brain tumors
- machine learning
- Neuroimaging
Grants and Projects
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- Noninvasive Metabolic Signatures to Improve Management of Molecular Subtypes of Glioma, NIH, 2005-2024
- Brain Vascular Malformation Consortium: Predictor's of Clinical Course, NIH, 2009-2024
- Mitigation of preanalytic factors influencing brain tumor protein phosphorylation, NIH, 2019-2024
- Brain Tumor SPORE Grant, NIH, 2002-2023
- Improved Monitoring of Premanifest and Early Huntingtons Using 7T Multimodal Mri, NIH, 2017-2022
- 3D Multi-Contrast MRI with Automatic Brain Tissue and Lesion Segmentation, NIH, 2019-2021
- Microbleeds as a Marker of Radiation-induced Brain Injury in Pediatric Patients, NIH, 2015-2021
Publications (87)
Top publication keywords:
Hemangioma, Cavernous, Central Nervous SystemGlioblastomaPerfusionCerebral VeinsGliomaMagnetic Resonance SpectroscopyImage Processing, Computer-AssistedMagnetic Resonance ImagingRadiation InjuriesVascular System InjuriesImage Interpretation, Computer-AssistedBrain NeoplasmsCerebral HemorrhageCerebral ArteriesEcho-Planar Imaging
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Quantitative assessment of preanalytic variables on clinical evaluation of PI3/AKT/mTOR signaling activity in diffuse glioma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2024 Beccari S, Mohamed E, Voong V, Hilz S, Lafontaine M, Shai A, Lim Y, Martinez J, Switzman B, Yu RL, Lupo JM, Chang EF, Hervey-Jumper SL, Berger MS, Costello JF, Phillips JJ -
Noninvasive Autopsy-Validated Tumor Probability Maps Identify Glioma Invasion Beyond Contrast Enhancement.
Neurosurgery 2024 Bobholz SA, Lowman AK, Connelly JM, Duenweg SR, Winiarz A, Nath B, Kyereme F, Brehler M, Bukowy J, Coss D, Lupo JM, Phillips JJ, Ellingson BM, Krucoff MO, Mueller WM, Banerjee A, LaViolette PS -
Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
Cell 2024 Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q, Youngblood MW, Stasiak LA, Hou Y, Wang J, Yamaguchi TN, Lafontaine M, Shai A, Smirnov IV, Solomon DA, … -
Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach.
Cancers 2024 Autry AW, Vaziri S, Gordon JW, Chen HY, Kim Y, Dang D, LaFontaine M, Noeske R, Bok R, Villanueva-Meyer JE, Clarke JL, Oberheim Bush NA, Chang SM, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Li Y -
Altered Iron and Microstructure in Huntington's Disease Subcortical Nuclei: Insight From 7T MRI.
Journal of magnetic resonance imaging : JMRI 2024 Yao J, Morrison MA, Jakary A, Avadiappan S, Rowley P, Glueck J, Driscoll T, Geschwind MD, Nelson AB, Possin KL, Xu D, Hess CP, Lupo JM
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Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part I: Event Rates and Clinical Outcome.
Stroke 2023 Flemming KD, Kim H, Hage S, Mandrekar J, Kinkade S, Girard R, Torbey M, Huang J, Huston J, Shu Y, Lanzino G, Selwyn R, Hart B, Mabray M, Feghali J, Sair HI, Narvid J, Lupo JM, Lee J, Stadnik A, … -
Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling.
Stroke 2023 Hage S, Kinkade S, Girard R, Flemming KD, Kim H, Torbey MT, Huang J, Huston J, Shu Y, Selwyn RG, Hart BL, Mabray MC, Feghali J, Sair HI, Narvid J, Lupo JM, Lee J, Stadnik A, Alcazar-Felix RJ, Shenkar … -
Ethical considerations of preclinical models in imaging research.
Magnetic resonance in medicine 2023 Garza-Villarreal EA, Moy L, Mao H, Hussain T, Lupo JM, Fleischer CC, Scott AD -
Evaluation of deep learning models for quality control of MR spectra.
Frontiers in neuroscience 2023 Vaziri S, Liu H, Xie E, Ratiney H, Sdika M, Lupo JM, Xu D, Li Y -
Ethical Considerations for MRI Research in Human Subjects in the Era of Precision Medicine.
Journal of magnetic resonance imaging : JMRI 2023 Mao H, Garza-Villarreal EA, Moy L, Hussain T, Scott AD, Lupo JM, Zhou XJ, Fleischer CC -
Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas.
NeuroImage. Clinical 2023 Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y -
Cavernous Angioma Symptomatic Hemorrhage (CASH) Trial Readiness II: Imaging Biomarkers and Trial Modeling.
medRxiv : the preprint server for health sciences 2023 Hage S, Kinkade S, Girard R, Flemming KD, Kim H, Torbey MT, Huang J, Huston J, Shu Y, Selwyn RG, Hart BL, Mabray MC, Feghali J, Sair HI, Narvid J, Lupo JM, Lee J, Stadnik A, Alcazar R, Shenkar R, … -
Editorial for "Relationship Between Microstructural Alterations and Cognitive Decline After Whole-Brain Radiation Therapy for Brain Metastases: An Exploratory Whole-Brain MR Analysis Based on Neurite Orientation Dispersion and Density Imaging".
Journal of magnetic resonance imaging : JMRI 2023 Yao J, Morrison MA, Lupo JM -
Evaluation of major depressive disorder using 7 Tesla phase sensitive neuroimaging before and after mindfulness-based cognitive therapy.
Journal of affective disorders 2023 Jakary A, Lupo JM, Mackin S, Yin A, Murray D, Yang T, Mukherjee P, Larson P, Xu D, Eisendrath S, Luks T, Li Y -
A feasibility study for quantitative assessment of cerebrovascular malformations using flutriciclamide ([18F]GE-180) PET/MRI.
Frontiers in medicine 2023 Kim SJW, Lupo JM, Chen Y, Pampaloni MH, VanBrocklin HF, Narvid J, Kim H, Seo Y -
DeepSWI: Using Deep Learning to Enhance Susceptibility Contrast on T2*-Weighted MRI.
Journal of magnetic resonance imaging : JMRI 2023 Genc O, Morrison MA, Villanueva-Meyer JE, Burns B, Hess CP, Banerjee S, Lupo JM -
Comparison of quantitative susceptibility mapping methods for iron-sensitive susceptibility imaging at 7T: An evaluation in healthy subjects and patients with Huntington's disease.
NeuroImage 2022 Yao J, Morrison MA, Jakary A, Avadiappan S, Chen Y, Luitjens J, Glueck J, Driscoll T, Geschwind MD, Nelson AB, Villanueva-Meyer JE, Hess CP, Lupo JM -
Longitudinal MR spectroscopy to detect progression in patients with lower-grade glioma in the surveillance phase.
Neuro-oncology advances 2022 Avalos LN, Luks TL, Gleason T, Damasceno P, Li Y, Lupo JM, Phillips J, Oberheim Bush NA, Taylor JW, Chang SM, Villanueva-Meyer JE -
Functional network alterations in young brain tumor patients with radiotherapy-induced memory impairments and vascular injury.
Frontiers in neurology 2022 Morrison MA, Walter S, Mueller S, Felton E, Jakary A, Stoller S, Molinaro AM, Braunstein SE, Hess CP, Lupo JM -
Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-13C]pyruvate MRI data from patients with glioma.
NeuroImage. Clinical 2022 Vaziri S, Autry AW, Lafontaine M, Kim Y, Gordon JW, Chen HY, Hu JY, Lupo JM, Chang SM, Clarke JL, Villanueva-Meyer JE, Bush NAO, Xu D, Larson PEZ, Vigneron DB, Li Y -
Improving the Automatic Classification of Brain MRI Acquisition Contrast with Machine Learning.
Journal of digital imaging 2022 Cluceru J, Lupo JM, Interian Y, Bove R, Crane JC -
An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro).
Frontiers in oncology 2022 Kline C, Stoller S, Byer L, Samuel D, Lupo JM, Morrison MA, Rauschecker AM, Nedelec P, Faig W, Dubal DB, Fullerton HJ, Mueller S -
Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging.
Neuro-oncology 2022 Cluceru J, Interian Y, Phillips JJ, Molinaro AM, Luks TL, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Shai A, Chunduru P, Pedoia V, Villanueva-Meyer JE, Chang SM, Lupo JM -
Comparison of quantitative susceptibility mapping methods on evaluating radiation-induced cerebral microbleeds and basal ganglia at 3T and 7T.
NMR in biomedicine 2022 Chen Y, Genc O, Poynton CB, Banerjee S, Hess CP, Lupo JM -
Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project.
Stroke 2021 Kim H, Flemming KD, Nelson JA, Lui A, Majersik JJ, Cruz MD, Zabramski J, Trevizo O, Lanzino G, Zafar A, Torbey M, Mabray MC, Robinson M, Narvid J, Lupo J, Thompson RE, Hanley DF, McBee N, Treine K, … -
Relationship between 7T MR-angiography features of vascular injury and cognitive decline in young brain tumor patients treated with radiation therapy.
Journal of neuro-oncology 2021 Avadiappan S, Morrison MA, Jakary A, Felton E, Stoller S, Hess CP, Molinaro AM, Braunstein SE, Mueller S, Lupo JM -
7-T Magnetic Resonance Imaging in the Management of Brain Tumors.
Magnetic resonance imaging clinics of North America 2021 Morrison MA, Lupo JM -
Pilot Study of Hyperpolarized 13C Metabolic Imaging in Pediatric Patients with Diffuse Intrinsic Pontine Glioma and Other CNS Cancers.
AJNR. American journal of neuroradiology 2020 Autry AW, Park I, Kline C, Chen HY, Gordon JW, Raber S, Hoffman C, Kim Y, Okamoto K, Vigneron DB, Lupo JM, Prados M, Li Y, Xu D, Mueller S -
Diffusion MRI as an early marker of response to immune checkpoint inhibitors.
Neuro-oncology 2020 Lupo JM -
Longitudinal outcomes of cochlear implantation and bimodal hearing in a large group of adults: A multicenter clinical study.
American journal of otolaryngology 2020 Kelsall D, Lupo J, Biever A -
Centrally Reduced Diffusion Sign for Differentiation between Treatment-Related Lesions and Glioma Progression: A Validation Study.
AJNR. American journal of neuroradiology 2020 Alcaide-Leon P, Cluceru J, Lupo JM, Yu TJ, Luks TL, Tihan T, Bush NA, Villanueva-Meyer JE -
Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas.
Neuro-oncology 2020 Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM -
Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2020 Morrison MA, Mueller S, Felton E, Jakary A, Stoller S, Avadiappan S, Yuan J, Molinaro AM, Braunstein S, Banerjee A, Hess CP, Lupo JM -
Simultaneous multi-slice spin- and gradient-echo dynamic susceptibility-contrast perfusion-weighted MRI of gliomas.
NMR in biomedicine 2020 Han M, Yang B, Fernandez B, Lafontaine M, Alcaide-Leon P, Jakary A, Burns BL, Morrison MA, Villanueva-Meyer JE, Chang SM, Banerjee S, Lupo JM -
Characterization of serial hyperpolarized 13C metabolic imaging in patients with glioma.
NeuroImage. Clinical 2020 Autry AW, Gordon JW, Chen HY, LaFontaine M, Bok R, Van Criekinge M, Slater JB, Carvajal L, Villanueva-Meyer JE, Chang SM, Clarke JL, Lupo JM, Xu D, Larson PEZ, Vigneron DB, Li Y -
A Fully Automated Method for Segmenting Arteries and Quantifying Vessel Radii on Magnetic Resonance Angiography Images of Varying Projection Thickness.
Frontiers in neuroscience 2020 Avadiappan S, Payabvash S, Morrison MA, Jakary A, Hess CP, Lupo JM -
QSMGAN: Improved Quantitative Susceptibility Mapping using 3D Generative Adversarial Networks with increased receptive field.
NeuroImage 2019 Chen Y, Jakary A, Avadiappan S, Hess CP, Lupo JM -
Treatment-induced lesions in newly diagnosed glioblastoma patients undergoing chemoradiotherapy and heat-shock protein vaccine therapy.
Journal of neuro-oncology 2019 Alcaide-Leon P, Luks TL, Lafontaine M, Lupo JM, Okada H, Clarke JL, Villanueva-Meyer JE -
Toward Automatic Detection of Radiation-Induced Cerebral Microbleeds Using a 3D Deep Residual Network.
Journal of digital imaging 2019 Chen Y, Villanueva-Meyer JE, Morrison MA, Lupo JM -
Technical Note: Simultaneous segmentation and relaxometry for MRI through multitask learning.
Medical physics 2019 Cao P, Liu J, Tang S, Leynes AP, Lupo JM, Xu D, Larson PEZ -
Correlation of Tumor Perfusion Between Carbon-13 Imaging with Hyperpolarized Pyruvate and Dynamic Susceptibility Contrast MRI in Pre-Clinical Model of Glioblastoma.
Molecular imaging and biology 2019 Park I, Lupo JM, Nelson SJ -
Risk factors of radiotherapy-induced cerebral microbleeds and serial analysis of their size compared with white matter changes: A 7T MRI study in 113 adult patients with brain tumors.
Journal of magnetic resonance imaging : JMRI 2019 Morrison MA, Hess CP, Clarke JL, Butowski N, Chang SM, Molinaro AM, Lupo JM -
Machine Learning in Neurooncology Imaging: From Study Request to Diagnosis and Treatment.
AJR. American journal of roentgenology 2018 Villanueva-Meyer JE, Chang P, Lupo JM, Hess CP, Flanders AE, Kohli M -
A comparison of coil combination strategies in 3D multi-channel MRSI reconstruction for patients with brain tumors.
NMR in biomedicine 2018 Vareth M, Lupo J, Larson P, Nelson S -
A user-guided tool for semi-automated cerebral microbleed detection and volume segmentation: Evaluating vascular injury and data labelling for machine learning.
NeuroImage. Clinical 2018 Morrison MA, Payabvash S, Chen Y, Avadiappan S, Shah M, Zou X, Hess CP, Lupo JM -
Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor.
Translational oncology 2017 Autry A, Phillips JJ, Maleschlijski S, Roy R, Molinaro AM, Chang SM, Cha S, Lupo JM, Nelson SJ -
Relationship between radiation dose and microbleed formation in patients with malignant glioma.
Radiation oncology (London, England) 2017 Wahl M, Anwar M, Hess CP, Chang SM, Lupo JM -
Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
Cancer 2017 Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D -
Identifying Voxels at Risk for Progression in Glioblastoma Based on Dosimetry, Physiologic and Metabolic MRI.
Radiation research 2017 Anwar M, Molinaro AM, Morin O, Chang SM, Haas-Kogan DA, Nelson SJ, Lupo JM -
Automated algorithm for counting microbleeds in patients with familial cerebral cavernous malformations.
Neuroradiology 2017 Zou X, Hart BL, Mabray M, Bartlett MR, Bian W, Nelson J, Morrison LA, McCulloch CE, Hess CP, Lupo JM, Kim H -
Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors.
Neuro-oncology 2016 Roddy E, Sear K, Felton E, Tamrazi B, Gauvain K, Torkildson J, Buono BD, Samuel D, Haas-Kogan DA, Chen J, Goldsby RE, Banerjee A, Lupo JM, Molinaro AM, Fullerton HJ, Mueller S -
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
Journal of neuro-oncology 2016 Nelson SJ, Li Y, Lupo JM, Olson M, Crane JC, Molinaro A, Roy R, Clarke J, Butowski N, Prados M, Cha S, Chang SM -
Magnetic resonance analysis of malignant transformation in recurrent glioma.
Neuro-oncology 2016 Jalbert LE, Neill E, Phillips JJ, Lupo JM, Olson MP, Molinaro AM, Berger MS, Chang SM, Nelson SJ -
Investigating tumor perfusion by hyperpolarized 13 C MRI with comparison to conventional gadolinium contrast-enhanced MRI and pathology in orthotopic human GBM xenografts.
Magnetic resonance in medicine 2016 Park I, von Morze C, Lupo JM, Ardenkjaer-Larsen JH, Kadambi A, Vigneron DB, Nelson SJ -
Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials.
Translational oncology 2015 Wen Q, Jalilian L, Lupo JM, Li Y, Roy R, Molinaro AM, Chang SM, Prados M, Butowski N, Clarke J, Nelson SJ -
Magnetic Resonance (MR) Metabolic Imaging in Glioma.
Brain pathology (Zurich, Switzerland) 2015 Chaumeil MM, Lupo JM, Ronen SM -
Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T.
NeuroImage. Clinical 2015 Wen Q, Kelley DA, Banerjee S, Lupo JM, Chang SM, Xu D, Hess CP, Nelson SJ -
The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma.
Neuro-oncology 2015 Lupo JM, Molinaro AM, Essock-Burns E, Butowski N, Chang SM, Cha S, Nelson SJ -
Simultaneous imaging of radiation-induced cerebral microbleeds, arteries and veins, using a multiple gradient echo sequence at 7 Tesla.
Journal of magnetic resonance imaging : JMRI 2014 Bian W, Banerjee S, Kelly DA, Hess CP, Larson PE, Chang SM, Nelson SJ, Lupo JM -
Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
Journal of neuro-oncology 2014 Wen Q, Jalilian L, Lupo JM, Molinaro AM, Chang SM, Clarke J, Prados M, Nelson SJ -
Advanced magnetic resonance imaging methods for planning and monitoring radiation therapy in patients with high-grade glioma.
Seminars in radiation oncology 2014 Lupo JM, Nelson SJ -
Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels.
Journal of magnetic resonance imaging : JMRI 2014 Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ -
Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
Cancer research 2014 Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM -
Quantitative 7T phase imaging in premanifest Huntington disease.
AJNR. American journal of neuroradiology 2014 Apple AC, Possin KL, Satris G, Johnson E, Lupo JM, Jakary A, Wong K, Kelley DA, Kang GA, Sha SJ, Kramer JH, Geschwind MD, Nelson SJ, Hess CP -
Susceptibility-weighted MR imaging of radiation therapy-induced cerebral microbleeds in patients with glioma: a comparison between 3T and 7T.
Neuroradiology 2013 Bian W, Hess CP, Chang SM, Nelson SJ, Lupo JM -
Computer-aided detection of radiation-induced cerebral microbleeds on susceptibility-weighted MR images.
NeuroImage. Clinical 2013 Bian W, Hess CP, Chang SM, Nelson SJ, Lupo JM -
Survival analysis in patients with newly diagnosed glioblastoma using pre- and postradiotherapy MR spectroscopic imaging.
Neuro-oncology 2013 Li Y, Lupo JM, Parvataneni R, Lamborn KR, Cha S, Chang SM, Nelson SJ -
Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
Neuro-oncology 2013 Lupo JM, Essock-Burns E, Molinaro AM, Cha S, Chang SM, Butowski N, Nelson SJ -
Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM.
Journal of magnetic resonance imaging : JMRI 2012 Essock-Burns E, Phillips JJ, Molinaro AM, Lupo JM, Cha S, Chang SM, Nelson SJ -
A serial in vivo 7T magnetic resonance phase imaging study of white matter lesions in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012 Bian W, Harter K, Hammond-Rosenbluth KE, Lupo JM, Xu D, Kelley DA, Vigneron DB, Nelson SJ, Pelletier D -
Performance of two commercially available automated immunoassays for the determination of Epstein-Barr virus serological status.
Clinical and vaccine immunology : CVI 2012 Lupo J, Germi R, Semenova T, Buisson M, Seigneurin JM, Morand P -
T1 and T2 Metabolite Relaxation Times in Normal Brain at 3T and 7T
J Mol Imaging Dynam 2012 Li Y, Xu D, Ozturk-Isik E, Lupo JM, Chen AP, Vigneron DB, Nelson SJ. -
Advances in ultra-high field MRI for the clinical management of patients with brain tumors.
Current opinion in neurology 2011 Lupo JM, Li Y, Hess CP, Nelson SJ -
7-Tesla susceptibility-weighted imaging to assess the effects of radiotherapy on normal-appearing brain in patients with glioma.
International journal of radiation oncology, biology, physics 2011 Lupo JM, Chuang CF, Chang SM, Barani IJ, Jimenez B, Hess CP, Nelson SJ -
Serial analysis of imaging parameters in patients with newly diagnosed glioblastoma multiforme.
Neuro-oncology 2011 Li Y, Lupo JM, Polley MY, Crane JC, Bian W, Cha S, Chang S, Nelson SJ -
Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
Neuro-oncology 2010 Essock-Burns E, Lupo JM, Cha S, Polley MY, Butowski NA, Chang SM, Nelson SJ -
Multi-channel metabolic imaging, with SENSE reconstruction, of hyperpolarized [1-(13)C] pyruvate in a live rat at 3.0 tesla on a clinical MR scanner.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2010 Tropp J, Lupo JM, Chen A, Calderon P, McCune D, Grafendorfer T, Ozturk-Isik E, Larson PE, Hu S, Yen YF, Robb F, Bok R, Schulte R, Xu D, Hurd R, Vigneron D, Nelson S -
Multiparametric characterization of grade 2 glioma subtypes using magnetic resonance spectroscopic, perfusion, and diffusion imaging.
Translational oncology 2009 Bian W, Khayal IS, Lupo JM, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ -
Analysis of hyperpolarized dynamic 13C lactate imaging in a transgenic mouse model of prostate cancer.
Magnetic resonance imaging 2009 Lupo JM, Chen AP, Zierhut ML, Bok RA, Cunningham CH, Kurhanewicz J, Vigneron DB, Nelson SJ -
GRAPPA-based susceptibility-weighted imaging of normal volunteers and patients with brain tumor at 7 T.
Magnetic resonance imaging 2008 Lupo JM, Banerjee S, Hammond KE, Kelley DA, Xu D, Chang SM, Vigneron DB, Majumdar S, Nelson SJ -
Pulse sequence for dynamic volumetric imaging of hyperpolarized metabolic products.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008 Cunningham CH, Chen AP, Lustig M, Hargreaves BA, Lupo J, Xu D, Kurhanewicz J, Hurd RE, Pauly JM, Nelson SJ, Vigneron DB -
Development of a robust method for generating 7.0 T multichannel phase images of the brain with application to normal volunteers and patients with neurological diseases.
NeuroImage 2007 Hammond KE, Lupo JM, Xu D, Metcalf M, Kelley DA, Pelletier D, Chang SM, Mukherjee P, Vigneron DB, Nelson SJ -
Analysis of metabolic indices in regions of abnormal perfusion in patients with high-grade glioma.
AJNR. American journal of neuroradiology 2007 Lupo JM, Cha S, Chang SM, Nelson SJ -
Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.
AJNR. American journal of neuroradiology 2007 Cha S, Lupo JM, Chen MH, Lamborn KR, McDermott MW, Berger MS, Nelson SJ, Dillon WP -
Feasibility of dynamic susceptibility contrast perfusion MR imaging at 3T using a standard quadrature head coil and eight-channel phased-array coil with and without SENSE reconstruction.
Journal of magnetic resonance imaging : JMRI 2006 Lupo JM, Lee MC, Han ET, Cha S, Chang SM, Berger MS, Nelson SJ -
Partially-parallel, susceptibility-weighted MR imaging of brain vasculature at 7 Tesla using sensitivity encoding and an autocalibrating parallel technique.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2006 Lupo JM, Banerjee S, Kelley D, Xu D, Vigneron DB, Majumdar S, Nelson SJ -
Dynamic susceptibility-weighted perfusion imaging of high-grade gliomas: characterization of spatial heterogeneity.
AJNR. American journal of neuroradiology 2005 Lupo JM, Cha S, Chang SM, Nelson SJ