James Chen
Assistant Professor
Orofacial Sciences
School of Dentistry

Grants and Projects

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• Assessment of outcomes and cost-effectiveness in early orthodontic treatment, NIH, 2013-2021

Publications (6)

Top publication keywords:
JNK Mitogen-Activated Protein KinasesUbiquitin-Protein Ligase ComplexesProto-Oncogene Proteins c-junAmelogeninFluoridesApatitesMitosisSaccharomyces cerevisiae ProteinsCariostatic AgentsToothCalciumLigasesMatrix Metalloproteinase 20AmeloblastsDental Enamel

• Calcium-mediated differentiation of ameloblast lineage cells in vitro.
  Journal of experimental zoology. Part B, Molecular and developmental evolution 2009 Chen J, Zhang Y, Mendoza J, Denbesten P
• Comparative properties of recombinant human and bovine matrix metalloproteinase-20.
  Archives of oral biology 2008 Zhu L, Tanimoto K, Robinsin S, Chen J, Witkowska E, Hall S, Le T, Denbesten PK, Li W
• Effects of fluoride on the interactions between amelogenin and apatite crystals.
  Journal of dental research 2008 Tanimoto K, Le T, Zhu L, Chen J, Featherstone JD, Li W, DenBesten P
• JNK/c-Jun signaling pathway mediates the fluoride-induced down-regulation of MMP-20 in vitro.
  Matrix biology : journal of the International Society for Matrix Biology 2007 Zhang Y, Li W, Chi HS, Chen J, Denbesten PK
• The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition.
  The Journal of cell biology 2002 Kang D, Chen J, Wong J, Fang G
• MAD2B is an inhibitor of the anaphase-promoting complex.
  Genes & development 2001 Chen J, Fang G