Jaehoon Shin, MD, PhD
Assistant Professor
Radiology
School of Medicine

Dr. Shin earned his MD at Seoul National University, South Korea in 2008, followed by a PhD at Johns Hopkins University in 2016. His clinical training includes an internship year at MedStar Harbor Hospital in Baltimore followed by a diagnostic radiology residency with early specialization in interventional radiology (ESIR) at UCSF. In 2022, Dr. Shin completed an interventional radiology fellowship, also at UCSF.

Dr. Shin received the prestigious Samsung Scholarship for doctoral study, and was awarded Best Case in Neuroradiology at the 2019 American Institute for Radiologic Pathology. Dr. Shin is a collaborator on a Medical Research Award from the Robert J. & Helen C. Kleberg Foundation, and principal investigator for a Society for Interventional Radiology Pilot Research Grant. Dr. Shin’s research addresses novel T cell-based imaging (synNotch-PET), which has the potential to detect early cancers and pre-cancerous lesions. Additional research projects include locoregional T cell therapy to enhance treatments for pancreatic cancer and glioblastoma and single-cell RNA sequencing to better understand venous insufficiency and druggable target biological processes.

• Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.
  Neuron 2017 Beckervordersandforth R, Ebert B, Schäffner I, Moss J, Fiebig C, Shin J, Moore DL, Ghosh L, Trinchero MF, Stockburger C, Friedland K, Steib K, von Wittgenstein J, Keiner S, Redecker C, Hölter SM, …
• Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth.
  Cell stem cell 2016 Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL
• Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression.
  Molecular cell 2015 Zeng Y, Yao B, Shin J, Lin L, Kim N, Song Q, Liu S, Su Y, Guo JU, Huang L, Wan J, Wu H, Qian J, Cheng X, Zhu H, Ming GL, Jin P, Song H
• Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis.
  Cell stem cell 2015 Shin J, Berg DA, Zhu Y, Shin JY, Song J, Bonaguidi MA, Enikolopov G, Nauen DW, Christian KM, Ming GL, Song H
• Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair.
  Nature neuroscience 2015 Yu H, Su Y, Shin J, Zhong C, Guo JU, Weng YL, Gao F, Geschwind DH, Coppola G, Ming GL, Song H
• Seeking a roadmap toward neuroepigenetics.
  Neuron 2015 Shin J, Ming GL, Song H
• Molecular toggle switch of histone demethylase LSD1.
  Molecular cell 2015 Shin J, Ming GL, Song H
• Decoding neural transcriptomes and epigenomes via high-throughput sequencing.
  Nature neuroscience 2014 Shin J, Ming GL, Song H
• DNA modifications in the mammalian brain.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2014 Shin J, Ming GL, Song H
• Synaptic dysregulation in a human iPS cell model of mental disorders.
  Nature 2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis …
• Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain.
  Nature neuroscience 2013 Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B, Zhong C, Hu S, Le T, Fan G, Zhu H, Chang Q, Gao Y, Ming GL, Song H
• DNA modifications and neurological disorders.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2013 Weng YL, An R, Shin J, Song H, Ming GL
• DNA methylation presents distinct binding sites for human transcription factors.
  eLife 2013 Hu S, Wan J, Su Y, Song Q, Zeng Y, Nguyen HN, Shin J, Cox E, Rho HS, Woodard C, Xia S, Liu S, Lyu H, Ming GL, Wade H, Song H, Qian J, Zhu H
• By hook or by crook: multifaceted DNA-binding properties of MeCP2.
  Cell 2013 Shin J, Ming GL, Song H
• Platelet-rich plasma enhances the dermal regeneration efficacy of human adipose-derived stromal cells administered to skin wounds.
  Cell transplantation 2012 Bhang SH, Park J, Yang HS, Shin J, Kim BS
• Enhanced cartilage formation via three-dimensional cell engineering of human adipose-derived stem cells.
  Tissue engineering. Part A 2012 Yoon HH, Bhang SH, Shin JY, Shin J, Kim BS
• Enhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma.
  Experimental & molecular medicine 2011 Yang HS, Shin J, Bhang SH, Shin JY, Park J, Im GI, Kim CS, Kim BS