Ian Harris, MD
Professor
Medicine
School of Medicine

Dr. Harris' research focuses generally on the molecular mechanisms underlying cardiac development and growth and specifically on the transcriptional control of genes during cardiac development. Dr. Harris earned his degree from UCSF School of Medicine and completed his internship and residency in Internal Medicine at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. He went on to complete a research fellowship in cardiology/cell signaling in the laboratory of Dr. Anthony Muslin and then a chief residency in Internal Medicine at Washington University. Dr. Harris returned to UCSF Medical Center to complete his cardiology and adult congenital cardiology fellowships, as well as a research fellowship in developmental biology in the lab of Dr. Brian Black. Dr. Harris joined the University of California, San Francisco cardiology team in 2007.

• Outcomes among adult survivors of total cavopulmonary Fontan palliation for single ventricle.
  Heart (British Cardiac Society) 2022 Anigwe C, Yogeswaran V, Moon-Grady A, McAllister S, Aggarwal A, Blissett S, Harris IS, Kouretas PC, Mahadevan VS, Sabanayagam A, Agarwal A
• Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro.
  Virology 2021 Raymonda MH, Ciesla JH, Monaghan M, Leach J, Asantewaa G, Smorodintsev-Schiller LA, Lutz MM, Schafer XL, Takimoto T, Dewhurst S, Munger J, Harris IS
• Abstract 12644: Clinical Features and Outcomes by Systemic Ventricle Morphology in Adult Fontan Patients.
  Circulation 2021 Jessica M Hong, Vidhushei Yogeswaran, Christopher Anigwe, Anita J Moon-Grady, Ian S Harris, peter kouretas, Vaikom S Mahadevan, Anushree Agarwal
• Abstract 13179: Rates and Reasons for Emergency Department Use Among US Adults With Congenital Heart Disease.
  Circulation 2021 Jessica M Hong, Aarthi Sabanayagam, Ian S Harris, peter kouretas, Vaikom S Mahadevan, Shunji Sano, Anushree Agarwal
• Abstract 13185: Emergency Department Total and Out-of-Pocket Costs for Adults With Congenital Heart Disease in the United States.
  Circulation 2021 Jessica M Hong, Aarthi Sabanayagam, Ian S Harris, Peter Kouretas, Vaikom S Mahadevan, Shunji Sano
• Association of Insurance Status With Emergent Versus Nonemergent Hospital Encounters Among Adults With Congenital Heart Disease.
  Journal of the American Heart Association 2021 Agarwal A, Gurvitz M, Myers J, Jain S, Khan AM, Nah G, Harris IS, Kouretas P, Marcus GM
• Cardiac Remodelling in Adults Following Percutaneous PDA closure: A Meta-analysis.
  International Journal of Cardiology Congenital Heart Disease 2021 Sarah Blissett, Harsh Agrawal, Ahmed Kheiwa, Hope Caughron, Ian S. Harris, Anu Agarwal, Elyse Foster, Indika Mallawaarachchi, Vaikom S. Mahadevan
• CLINICAL OUTCOMES OF ADULTS WITH HYPOPLASTIC LEFT HEART SYNDROME: IS THERE A WAY TO IDENTIFY A GOOD FONTAN?.
  Journal of the American College of Cardiology 2021 Sophie McAllister, Christopher Anigwe, Vidhushei Yogeswaran, Anita Moon-Grady, Ian Harris, Peter Kouretas, Anushree Agarwal
• A practical guide to echocardiographic evaluation of adult Fontan patients.
  Echocardiography (Mount Kisco, N.Y.) 2020 Kheiwa A, Harris IS, Varadarajan P
• Echocardiographic differences between D-TGA and L-TGA in adult patients.
  Echocardiography (Mount Kisco, N.Y.) 2020 Kheiwa A, Harris IS, Varadarajan P
• Seguridad de la extracción transvenosa de electrodos en las cardiopatías congénitas del adulto: una perspectiva nacional.
  Revista Española de Cardiología 2020 Xiaofan Guo, Robert M. Hayward, Eric Vittinghoff, Sun Yong Lee, Ian S. Harris, Mark J. Pletcher, Byron K. Lee
• Abstract 15358: Cardiac Remodeling in Adults Following Percutaneous Patent Ductus Arteriosus Closure: A Meta-analysis.
  Circulation 2020 Sarah Blissett, Harsh Agrawal, Ahmed Kheiwa, Hope Caughron, Ian Harris, Anushree Agarwal, Elyse Foster, Indika Mallawaarachchi, Vaikom Mahadevan
• Abstract 16601: Impact of Insurance Status on Emergent Versus Non-Emergent Hospital Encounters Among Adults With Congenital Heart Disease.
  Circulation 2020 Anushree Agarwal, Michelle Z GURVITZ, Janet Myers, Sarthak Jain, Abigail Khan, gregory nah, Ian S Harris, Vaikom S Mahadevan, Peter C Kouretas, Gregory M Marcus
• Safety of transvenous lead removal in adult congenital heart disease: a national perspective.
  Revista espanola de cardiologia (English ed.) 2020 Guo X, Hayward RM, Vittinghoff E, Lee SY, Harris IS, Pletcher MJ, Lee BK
• Catheter-Directed Thrombolysis for Submassive Pulmonary Embolism in the Third Trimester of Pregnancy.
  JACC. Case reports 2020 Compadre AJ, Kohi M, Lokken RP, Blissett S, Harris IS, Lucero J, Rosenstein MG, Sobhani NC
• BODY MASS INDEX AND HEMODYNAMICS IN THE ADULT FONTAN POPULATION.
  Journal of the American College of Cardiology 2020 Vidhushei Yogeswaran, Christopher Anigwe, Sarah Blissett, Anika Aggarwal, Anita Moon Grady, Elyse Foster, Vaikom S. Mahadevan, Ian Stewart Harris, Anushree Agarwal
• ELEVATED BODY MASS INDEX IN THE ADULT FONTAN POPULATION: CLINICAL FEATURES AND OUTCOMES.
  Journal of the American College of Cardiology 2020 Vidhushei Yogeswaran, Christopher Anigwe, Sarah Blissett, Anika Aggarwal, Anita Moon Grady, Elyse Foster, Vaikom S. Mahadevan, Ian Stewart Harris, Anushree Agarwal
• INCIDENCE AND CLINICAL PREDICTORS OF ADVERSE EVENTS IN ADULTS AFTER TOTAL CAVOPULMONARY FONTAN PALLIATION.
  Journal of the American College of Cardiology 2020 Christopher Anigwe, Vidhushei Yogeswaran, Anita Moon-Grady, Anika Aggarwal, Sarah Blissett, Ian Stewart Harris, Peter Kouretas, Vaikom S. Mahadevan, Elyse Foster, Anushree Agarwal
• PREDICTORS OF LONG-TERM MATERNAL CARDIOVASCULAR EVENTS AMONG WOMEN WITH CONGENITAL HEART DISEASE.
  Journal of the American College of Cardiology 2020 Hayley Schultz, Nasim C. Sobhani, Sarah Blissett, Juan M Gonzalez Velez, Ian Stewart Harris, Nisha Parikh, Molly Killion, Yolanda Tinajero, Elyse Foster, Anushree Agarwal
• Age- and Lesion-Related Comorbidity Burden Among US Adults With Congenital Heart Disease: A Population-Based Study.
  Journal of the American Heart Association 2019 Agarwal A, Thombley R, Broberg CS, Harris IS, Foster E, Mahadevan VS, John A, Vittinghoff E, Marcus GM, Dudley RA
• STIFF AND STRONG: DOES RESTRICTIVE RIGHT VENTRICULAR PHYSIOLOGY PROTECT RIGHT VENTRICULAR FUNCTION IN ADULTS WITH REPAIRED TETRALOGY OF FALLOT AND PULMONARY REGURGITATION?.
  Journal of the American College of Cardiology 2019 Sarah Blissett, Ahmed Kheiwa, Kelly Cordero, Anushree Agarwal, Elyse Foster, Ian Harris, Vaikom Mahadevan, Karen Ordovas
• Pregnancy complications and premature cardiovascular events among 1.6 million California pregnancies.
  Open heart 2019 Arnaout R, Nah G, Marcus G, Tseng Z, Foster E, Harris IS, Divanji P, Klein L, Gonzalez J, Parikh N
• Contraceptive Choices in the Immediate Postpartum Period in Women With Cardiac Disease.
  The American journal of cardiology 2019 Sobhani NC, Schultz H, Kheiwa A, Killion M, Parikh NI, Harris IS, Gonzalez JM, Agarwal A
• Abstract 17220: Risk Factors for Recurrent Peripartum Cardiomyopathy in 783 Women in California.
  Circulation 2018 Punag Divanji, Gregory Nah, Ian Harris, Anu Agarwal, Nisha I Parikh
• Understanding the Pediatric and Adult Healthcare System: Adapting to Change.
  2018 Megumi J. Okumura, Ian S. Harris, Mary Ellen Kleinhenz
• ATRIAL SEPTAL DEFECT IN ADULT PATIENT WITH EBSTEIN ANOMALY: TO CLOSE OR NOT TO CLOSE?.
  Journal of the American College of Cardiology 2018 Ahmed Kheiwa, Elyse Foster, Vaikom Mahadevan, Anushree Agarwal, Ian Harris
• Cardiopulmonary exercise testing in the evaluation of liver disease in adults who have had the Fontan operation.
  Archives of cardiovascular diseases 2017 Agarwal A, Cunnington C, Sabanayagam A, Zier L, McCulloch CE, Harris IS, Foster E, Atkinson D, Bryan A, Jenkins P, Dua J, Parker MJ, Karunaratne D, Moore JA, Meadows J, Clarke B, Hoschtitzky JA, …
• The efficacy of a video-based marker-less tracking system for gait analysis.
  Computer methods in biomechanics and biomedical engineering 2017 Ong A, Harris IS, Hamill J
• CORONARY ARTERY FISTULA IN PULMONARY ATRESIA WITH INTACT VENTRICULAR SEPTUM PHYSIOLOGY: TO CLOSE OR NOT TO CLOSE?.
  Journal of the American College of Cardiology 2017 Ahmed Kheiwa, Ian Harris, Anushree Agarwal, Vaikom Mahadevan, Aarthi Sabanayagam, Phillip Moore
• MORTALITY IN PREGNANT WOMEN WITH CONGENITAL HEART DISEASE: A SUBANALYSIS OF THE CALIFORNIA PREGNANCY-ASSOCIATED MORTALITY REVIEW.
  Journal of the American College of Cardiology 2017 Aarthi Sabanayagam, Anushree Agarwal, Christy MacCain, Elizabeth Lawton, Elliot Main, Afshan Hameed, Ian Harris, Elyse Foster
• PREVALENCE AND PREDICTORS OF ATRIAL TACHYARRHYTHMIAS IN ADULT FONTAN PATIENTS.
  Journal of the American College of Cardiology 2017 Anushree Agarwal, Aarthi Sabanayagam, Ahmed Kheiwa, Colin Cunnington, Ian Harris, Edward Gerstenfeld, Charles McCulloch, Elyse Foster, Zian Tseng, Lucas Zier, Petra Jenkins, Jaspal Dua, Devinda …
• PREVALENCE AND PREDICTORS OF PACEMAKER PLACEMENT IN ADULT FONTAN PATIENTS.
  Journal of the American College of Cardiology 2017 Anushree Agarwal, Aarthi Sabanayagam, Ahmed Kheiwa, Colin Cunnington, Edward Gerstenfeld, Charles McCulloch, Ian Harris, Zian Tseng, Elyse Foster, Petra Jenkins, Jaspal Dua, Devinda Karunaratne, …
• PREVALENCE OF ELEVATED BODY MASS INDEX AND ITS ASSOCIATION WITH CLINICAL FEATURES IN ADULT FONTAN PATIENTS.
  Journal of the American College of Cardiology 2017 Anushree Agarwal, Aarthi Sabanayagam, Ahmed Kheiwa, Colin Cunnington, Lucas Zier, Charles McCulloch, Ian Harris, Elyse Foster, Dougal Atkinson, Angela Bryan, Petra Jenkins, Jaspal Dua, Michael Parker,…
• SAFETY OF TRANSVENOUS LEAD REMOVAL IN ADULT CONGENITAL HEART DISEASE IN THE US.
  Journal of the American College of Cardiology 2017 Xiaofan Guo, Robert Hayward, Eric Vittinghoff, Sun Yong Lee, Ian Harris, Mark Pletcher, Byron Lee
• Coexistence of abnormal systolic motion of mitral valve in a consecutive group of 324 adult Tetralogy of Fallot patients assessed with echocardiography.
  Open heart 2016 Agarwal A, Harris IS, Mahadevan VS, Foster E
• Maternal arrhythmia and perinatal outcomes.
  Journal of perinatology : official journal of the California Perinatal Association 2016 Henry D, Gonzalez JM, Harris IS, Sparks TN, Killion M, Thiet MP, Bianco K
• MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.
  Development (Cambridge, England) 2016 Barnes RM, Harris IS, Jaehnig EJ, Sauls K, Sinha T, Rojas A, Schachterle W, McCulley DJ, Norris RA, Black BL
• Longitudinal development of obesity in the post-Fontan population.
  European journal of clinical nutrition 2015 Wellnitz K, Harris IS, Sapru A, Fineman JR, Radman M
• Can appropriate use criteria lead to appropriate care?
  Circulation. Cardiovascular quality and outcomes 2015 Lin GA, Harris IS
• 102: Pregnancy complications are increased among women with cardiomyopathy compared to those with other cardiac diseases.
  American Journal of Obstetrics and Gynecology 2015 Katherine Bianco, Ian Harris, Dana Henry, Molly Killion, Valerie Bosco, Mari-Paule Thiet, Juan Gonzalez
• Pathophysiology and Pharmacotherapy of Adult Congenital Heart Disease.
  Pathophysiology and Pharmacotherapy of Cardiovascular Disease 2015 Anushree Agarwal, Saurabh Aggarwal, Ian S. Harris
• Maternal Arrhythmia and Perinatal Outcomes.
  Obstetrics and Gynecology 2014 Dana Henry, Ian Harris, Valerie Bosco, Molly Killion, Mari-Paule Thiet, Katherine Bianco
• Reactive oxygen species delay control of lymphocytic choriomeningitis virus.
  Cell death and differentiation 2013 Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, Ohashi PS, Hengartner H, Zinkernagel RM…
• Management of pregnancy in patients with congenital heart disease.
  Progress in cardiovascular diseases 2011 Harris IS
• Development of the endocardium.
  Pediatric cardiology 2010 Harris IS, Black BL
• Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors.
  Cell 2008 De Val S, Chi NC, Meadows SM, Minovitsky S, Anderson JP, Harris IS, Ehlers ML, Agarwal P, Visel A, Xu SM, Pennacchio LA, Dubchak I, Krieg PA, Stainier DY, Black BL
• Transcriptional pathways in heart development.
  The FASEB Journal 2008 Brian L Black, Jione Kang, Ian S Harris, William Schachterle
• Determinants of myogenic specificity within MyoD are required for noncanonical E box binding.
  Molecular and cellular biology 2007 Heidt AB, Rojas A, Harris IS, Black BL
• Transcriptional control of second heart field development.
  Developmental Biology 2007 Brian L. Black, Jione Kang, Ian S. Harris, Will Schachterle, Anabel Rojas
• Current Diagnosis and Treatment in Cardiology, Crawford, M.H., ed
  Congenital Heart Disease in Adults 2007 Harris, I.S., and Foster, E.
• The AHA Clinical Cardiac Consult
  Renal Failure and the Cardiovascular System 2007 Harris, I.S. and Bader, D.S.
• Phonocardiographic timing of third and fourth heart sounds during acute myocardial infarction.
  Journal of electrocardiology 2006 Harris IS, Lee E, Yeghiazarians Y, Drew BJ, Michaels AD
• G-protein signaling participates in the development of diabetic cardiomyopathy.
  Diabetes 2004 Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ
• Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload.
  Circulation 2004 Harris IS, Zhang S, Treskov I, Kovacs A, Weinheimer C, Muslin AJ
• Washington Manual of Medical Therapeutics
  Washington Manual of Medical Therapeutics 2004 Harris, I.S., Lin, G.A., Green, G., Moylan, K.