Hua Su, MD
Professor
Anesthesia
School of Medicine
My research interests include: (1) adeno-associated viral vector (AAV)-mediated tissue specific gene transfer and gene expression; (2) the pathogenesis of cerebrovascular malformation; (3) development of new therapies for ischemic stroke and arteriovenous malformation; and (4) the impact of aging, peripheral injury (such as bone fracture), and innate immune response on stroke recovery.
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2019
- Postdoctoral Fellow Medicine University of California, San Francisco 1992
Websites
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- Center for Cerebrovascular Research (anesthesia.ucsf.edu)
- Profile at avm.ucsf.edu (avm.ucsf.edu)
Grants and Projects
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- Reduction of Brain AVM Severity through Inhibition of Pathogenic Angiogenesis, NIH, 2020-2025
- Uncover the Pathogenesis of Brain Arteriovenous Malformation, NIH, 1990-2023
- Cell type-specific influences on HHT pathogenesis, NIH, 2015-2019
- Soluble VEGF receptor therapy for brain arteriovenous malformation, NIH, 2014-2017
- Integrative Study of Brain Vascular Malformations, NIH/NINDS, 2002-2014
- Targeted Gene Expression in Ischemic Brain by Intravenous Delivery, NIH, 2010-2013
Publications (172)
Top publication keywords:
Arteriovenous FistulaIntracranial Arteriovenous MalformationsMemory, Long-TermFractures, Bonealpha7 Nicotinic Acetylcholine ReceptorActivin Receptors, Type IIntracranial HemorrhagesGenetic VectorsEndothelial CellsActivin Receptors, Type IIArteriovenous MalformationsVascular Endothelial Growth Factor ADependovirusEndoglinGene Transfer Techniques
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CNS resident macrophages enhance dysfunctional angiogenesis and circulating monocytes infiltration in brain arteriovenous malformation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Ma L, Zhu X, Tang C, Pan P, Yadav A, Liang R, Press K, Nelson J, Su H -
Abstract 116: Increased Collagen I/Collagen III Ratio is Associated With Hemorrhage in Brain Arteriovenous Malformations in Human and Mouse.
Stroke 2024 Zahra Shabani nabikandi, Joana Schurger, Alka Yadav, Rich Liang, Kelly Press, Shantel Weinsheimer, Annika Schmidt, Helen Kim, Hua Su -
Abstract TMP3: Overexpression of Alk1 in Brain Endothelial Cells Alleviates the Severity of Brain Arteriovenous Malformations in Alk1 Mutant Mice.
Stroke 2024 Alka Yadav, Rich Liang, Kelly Press, Annika Schmidt, Zahra Shabani nabikandi, Sally Huang, Trevor Gonzalez, Aravind Asokan, Hua Su -
Abstract TMP5: Mutation of Pdgfrß Enhances the Severity of Brain Arteriovenous Malformation on Endoglin Mutant Mice Through Exacerbation of Angiogenesis and Inflammation.
Stroke 2024 Alka Yadav, Leandro Barbosa Do Prado, Chaoliang Tang, Sonali Shaligram, Rich Liang, Kelly Press, Jasneet Dhaliwal, Ethan A Winkler, Hua Su -
Abstract TP2: Increase of EphrinB2/EphB4 Signaling Reduces the Severity of Brain Arteriovenous Malformation in Endoglin Deficient Mice Through Reduction of Angiogenesis and Inflammation.
Stroke 2024 Zahra Shabani nabikandi, Leandro Barbosa Do Prado, Alka Yadav, Rui Zhang, Wan Zhu, Sonali Shaligram, Joana Schuger, Rich Liang, Kelly Press, Hua Su
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Abstract WP318: Increased Synapse Elimination by Inflammatory Cells Contribute to Lon-Lasting Post-Stroke Memory Dysfunction in Aged Mice.
Stroke 2024 Zahra Shabani nabikandi, peipei Pan, Qifeng Li, Zhanqiang Wang, Kang Huo, Hua Su -
Increased Collagen I/Collagen III Ratio Is Associated with Hemorrhage in Brain Arteriovenous Malformations in Human and Mouse.
Cells 2024 Shabani Z, Schuerger J, Zhu X, Tang C, Ma L, Yadav A, Liang R, Press K, Weinsheimer S, Schmidt A, Wang C, Sekhar A, Nelson J, Kim H, Su H -
Vascular Dysfunctions Contribute to the Long-Term Cognitive Deficits Following COVID-19.
Biology 2023 Shabani Z, Liu J, Su H -
CNS resident macrophages enhance dysfunctional angiogenesis and circulating monocytes infiltration in brain arteriovenous malformation.
Research square 2023 Ma L, Zhu X, Tang C, Pan P, Yadav A, Liang R, Press K, Su H -
Abstract 52: Prevalence Of Somatic Activating Kras Mutations In Pediatric And Adult Sporadic Brain Arteriovenous Malformations.
Stroke 2023 Ethan A Winkler, Joseph Garcia, Cynthia Tsang, Jeffrey Nelson, Charles McCulloch, Shantel Weinsheimer, Christine K Fox, Heather Fullerton, Nerissa Ko, Hua Su, Tomasz Nowakowski, Daniel L Cooke, Steven… -
Cellular loci involved in the development of brain arteriovenous malformations.
Frontiers in human neuroscience 2022 Shabani Z, Schuerger J, Su H -
Remodeling of the Neurovascular Unit Following Cerebral Ischemia and Hemorrhage.
Cells 2022 Sato Y, Falcone-Juengert J, Tominaga T, Su H, Liu J -
Potential Targets for the Treatment of Brain Arteriovenous Malformations.
Translational stroke research 2022 Yadav A, Su H -
N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes.
Journal of neuroinflammation 2022 Joffre J, Wong E, Lawton S, Lloyd E, Nguyen N, Xu F, Sempio C, Kobzik L, Zlatanova I, Schumacher M, Klawitter J, Su H, Rabl K, Wilhelmsen K, Yeh CC, Hellman J -
Abstract 19: Long-lasting Post-stroke Memory Dysfunction In Aged Mice Is Like Due To Exacerbated Hippocampal Inflammation And Synapses Removing.
Stroke 2022 Peipei Pan, Qifeng Li, Zhanqiang Wang, Rich Liang, Kang Huo, Eric Ding, Chandler Beon, Kelly Press, Hua Su -
Abstract TMP5: Bone Marrow-derived And Clonally Expanded Alk1- Endothelial Cells Contribute To Brain Arteriovenous Malformation In Mice.
Stroke 2022 Sonali Shaligram, Rui Zhang, Wan Zhu, Li Ma, Man Luo, Qiang Li, Miriam Weiss, Thomas Arnold, Santander Grez NG, Rich Liang, Leandro Predo, Chaoliang Tang, Peipei Pan, Hua Su -
12 Genetics and Vascular Biology of Brain Vascular Malformations.
2022 Helen Kim, Ludmila Pawlikowska, Hua Su -
Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice.
Translational stroke research 2021 Shaligram SS, Zhang R, Zhu W, Ma L, Luo M, Li Q, Weiss M, Arnold T, Santander N, Liang R, do Prado L, Tang C, Pan F, Oh SP, Pan P, Su H -
Somatic mosaicism in the MAPK pathway in sporadic brain arteriovenous malformation and association with phenotype.
Journal of neurosurgery 2021 Gao S, Nelson J, Weinsheimer S, Winkler EA, Rutledge C, Abla AA, Gupta N, Shieh JT, Cooke DL, Hetts SW, Tihan T, Hess CP, Ko N, Walcott BP, McCulloch CE, Lawton MT, Su H, Pawlikowska L, Kim H -
Review of treatment and therapeutic targets in brain arteriovenous malformation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Pan P, Weinsheimer S, Cooke D, Winkler E, Abla A, Kim H, Su H -
Proof-of-concept single-arm trial of bevacizumab therapy for brain arteriovenous malformation.
BMJ neurology open 2021 Muster R, Ko N, Smith W, Su H, Dickey MA, Nelson J, McCulloch CE, Sneed PK, Clarke JL, Saloner DA, Eisenmenger L, Kim H, Cooke DL -
Abstract 63: Mutation of Platelet-Derived Growth Factor Receptor B Causes Cerebrovascular Malformation and Enhances Brain Arteriovenous Malformation Severity in Mice.
Stroke 2021 Leandro Prado, Chaoliang Tang, Sonali Shaligram, Rich Liang, Ethan Winkler, Hua Su -
Abstract P795: Activating Transcription Factor 3 Improves Stroke Recovery Through Reduction of Neuronal Damage and Neuroinflammation.
Stroke 2021 Zhanqiang Wang, Peipei Pan, Rich Liang, Qifeng Li, Janothon Pan, Zhonghui Guan, Hua Su -
Reduction of neuroinflammation alleviated mouse post bone fracture and stroke memory dysfunction.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Huo K, Wei M, Zhang M, Wang Z, Pan P, Shaligram SS, Huang J, Prado LBD, Wong J, Su H -
Bone Fracture Enhanced Blood-Brain Barrier Breakdown in the Hippocampus and White Matter Damage of Stroke Mice
International Journal of Molecular Science. 2020 J Huang, H Lyu, K Huo, LB Do Prado, C Tang,Z Wang, Q Li, J Wong, and H Su -
Bone Fracture Enhanced Blood-Brain Barrier Breakdown in the Hippocampus and White Matter Damage of Stroke Mice.
International journal of molecular sciences 2020 Huang J, Lyu H, Huo K, Do Prado LB, Tang C, Wang Z, Li Q, Wong J, Su H -
The role of mural cells in hemorrhage of brain arteriovenous malformation.
Brain hemorrhages 2020 Pan P, Shaligram SS, Do Prado LB, He L, Su H -
Reduction of endoglin receptor impairs mononuclear cell-migration.
Exploration of medicine 2020 Han Z, Shaligram S, Faughnan ME, Clark D, Sun Z, Su H -
Concurrent Presentation of Brain Arteriovenous Malformation, Peripheral Arteriovenous Malformation, and Cerebellar Astrocytoma: Case report.
Interdisciplinary Neurosurgery 2020 Ayushi Gautam, Zhengda Sun, Ethan Winkler, Hua Su, Tim McCalmont, Helen Kim, Tarik Tihan, William Y. Hoffman, Chris F. Dowd, Ilona J. Frieden, Daniel L. Cooke -
Concurrent presentation of brain arteriovenous malformation, peripheral arteriovenous malformation, and cerebellar astrocytoma: Case report.
Interdisciplinary neurosurgery : Advanced techniques and case management 2020 Gautam A, Sun Z, Winkler E, Su H, McCalmont TH, Kim H, Tihan T, Hoffman WY, Dowd CF, Frieden IJ, Cooke DL -
Abstract TP118: Activation of Alpha-7 Nicotinic Acetylcholine Receptor Improved Long-Term Cognitive Function of Mice With Long-Bone Fracture and Stroke.
Stroke 2020 Kang Hou, Meng Wei, Meng Zhang, Zhanqiang Wang, Sonali Shaligram, Jinhao Huang, Leandro Barbosa Do Prado, Julia Wong, Rose Carion, Tuanpeng Sun, Lei Zhan, Hua SU -
Abstract TP119: Tibia Fracture Leads to Long-Lasting Memory Dysfunction in Mice Through Enhanced Blood-Brain Barrie Breakdown in the Hippocampus and White Matter Damage.
Stroke 2020 Jinhao Huang, Haiyan Lyu, Kang Hou, Leandro Barbosa Do Prado, Chaoliang Tang, Zhanqiang Wang, Julia Wong, Hua Su -
Recent Advances in Basic Research for Brain Arteriovenous Malformation.
International journal of molecular sciences 2019 Barbosa Do Prado L, Han C, Oh SP, Su H -
Risk factors for hemorrhage of brain arteriovenous malformation.
CNS neuroscience & therapeutics 2019 Shaligram SS, Winkler E, Cooke D, Su H -
Effect of elevation of vascular endothelial growth factor level on exacerbation of hemorrhage in mouse brain arteriovenous malformation.
Journal of neurosurgery 2019 Cheng P, Ma L, Shaligram S, Walker EJ, Yang ST, Tang C, Zhu W, Zhan L, Li Q, Zhu X, Lawton MT, Su H -
Abstract 66: Reduction of the Number of Endothelial Cells Harboring Mutations of AVM Causative Genes Lessens Brain AVM Severity.
Stroke 2019 Sonali S Shaligram, Rui Zhang, Cameron M McDougall, Wan Zhu, Wan Zhu, Li Ma, Michael L Lawton, Hua Su -
Abstract TMP105: Elevation of VEGF Exacerbates Hemorrhage in Mouse Brain Arteriovenous Malformation.
Stroke 2019 Li Ma, Philip Cheng, Sonali Shaligram, Espen J Walker, Shun-Tai Yang, Chaoliang Tang, Wan Zhu, Qiang Li, Xiaonan Zhu, Hua Su -
Fracture shortly before stroke in mice leads to hippocampus inflammation and long-lasting memory dysfunction.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2019 Li Z, Wei M, Lyu H, Huo K, Wang L, Zhang M, Su H -
Induction of Brain Arteriovenous Malformation Through CRISPR/Cas9-Mediated Somatic Alk1 Gene Mutations in Adult Mice.
Translational stroke research 2018 Zhu W, Saw D, Weiss M, Sun Z, Wei M, Shaligram S, Wang S, Su H -
Reductions in brain pericytes are associated with arteriovenous malformation vascular instability.
Journal of neurosurgery 2018 Winkler EA, Birk H, Burkhardt JK, Chen X, Yue JK, Guo D, Rutledge WC, Lasker GF, Partow C, Tihan T, Chang EF, Su H, Kim H, Walcott BP, Lawton MT -
Risk factors for ischemic stroke post bone fracture.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2018 An Q, Chen Z, Huo K, Su H, Qu QM -
Impact of Bone Fracture on Ischemic Stroke Recovery.
International journal of molecular sciences 2018 Wei M, Lyu H, Huo K, Su H -
SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway.
Aging and disease 2018 Zhang M, Deng YN, Zhang JY, Liu J, Li YB, Su H, Qu QM -
Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model.
Stroke 2018 Zhu W, Chen W, Zou D, Wang L, Bao C, Zhan L, Saw D, Wang S, Winkler E, Li Z, Zhang M, Shen F, Shaligram S, Lawton M, Su H -
Animal Models and Prospective Therapeutic Targets for Brain Arteriovenous Malformation.
Molecular, Genetic, and Cellular Advances in Cerebrovascular Diseases 2018 Wan Zhu, Rui Zhang, Li Ma, Hua Su -
Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells.
Oncotarget 2017 Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL -
Inflammation and genetic factors in stroke pathogenesis.
Neuroimmunology and neuroinflammation 2017 Su H -
The roles of endoglin gene in cerebrovascular diseases.
Neuroimmunology and neuroinflammation 2017 Zhu W, Ma L, Zhang R, Su H -
Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis.
Translational stroke research 2017 Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z -
381 Reductions in Brain Pericytes are Associated with Arteriovenous Malformation Vascular Instability.
Neurosurgery 2017 Ethan A Winkler, Harjus Birk, Jan-Karl Burkhardt, Xiaolin Chen, John K Yue, Diana Guo, William Caleb Rutledge, George Lasker, Tarik Tihan, Edward F Chang, Hua Su, Helen Kim, Brian Patrick Walcott, … -
Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages.
Stroke 2017 Chen X, Cooke DL, Saloner D, Nelson J, Su H, Lawton MT, Hess C, Tihan T, Zhao Y, Kim H -
Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity.
Stroke 2017 Zhu W, Shen F, Mao L, Zhan L, Kang S, Sun Z, Nelson J, Zhang R, Zou D, McDougall CM, Lawton MT, Vu TH, Wu Z, Scaria A, Colosi P, Forsayeth J, Su H -
Morbidity after Hemorrhage in Children with Untreated Brain Arteriovenous Malformation.
Cerebrovascular diseases (Basel, Switzerland) 2017 Ma L, Kim H, Chen XL, Wu CX, Ma J, Su H, Zhao Y -
Abstract 125: Increased Endothelial Endoglin Gene Deletion and Co-deletion of EphrinB2 Enhance Brain Arteriovenous Malformation in Mice.
Stroke 2017 Rui Zhang, Wan Zhu, Li Ma, Man Luo, Lei Zhan, Hua Su -
Abstract 198: Endovascular Biopsy: in vivo Brain Aneurysm Endothelial Cell Sampling and Gene Expression Analysis.
Stroke 2017 Daniel L Cooke, Van Halbach, Steven Hetts, Matthew Amans, Christopher Dowd, Randall Higashida, Devon Lawson, Jeffrey Nelson, David McCoy, Helen Kim, Tomoki Hashimoto, Zena Werb, Hua Su, Zhengda Sun -
Abstract TMP111: Thalidomide and Lenalidomide Treatment Reduces Microhemorrhage in Brain Arteriovenous Malformation in Mice Through Increasing Mural Cell Coverage.
Stroke 2017 Wan Zhu, Dingquan Zou, Wanqiu Chen, Chen Bao, Rui Zhang, Lei Zhan, Zhengxi Li, Meng Zhang, Ethan Winkler, Michael T. Lawton, Hua Su -
Abstract TP445: Bevacizumab Therapy for Brain Arteriovenous Malformations.
Stroke 2017 Daniel L Cooke, Helen Kim, Wade Smith, Michael Lawton, Jennifer Clarke, David Saloner, Nerissa Ko, Patricia Sneed, Charles McCulloch, Hua Su -
Gene Therapy for Stroke.
Translational Research in Stroke 2017 Fanxia Shen, Hua Su -
Activation of Alpha-7 Nicotinic Acetylcholine Receptor Reduces Brain Edema in Mice with Ischemic Stroke and Bone Fracture.
Molecular neurobiology 2016 Zou D, Luo M, Han Z, Zhan L, Zhu W, Kang S, Bao C, Li Z, Nelson J, Zhang R, Su H -
Correction: Bone Fracture Pre-Ischemic Stroke Exacerbates Ischemic Cerebral Injury in Mice.
PloS one 2016 Wang L, Kang S, Zou D, Zhan L, Li Z, Zhu W, Su H -
Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice.
Translational stroke research 2016 Ma L, Shen F, Jun K, Bao C, Kuo R, Young WL, Nishimura SL, Su H -
Persistent infiltration and pro-inflammatory differentiation of monocytes cause unresolved inflammation in brain arteriovenous malformation.
Angiogenesis 2016 Zhang R, Han Z, Degos V, Shen F, Choi EJ, Sun Z, Kang S, Wong M, Zhu W, Zhan L, Arthur HM, Oh SP, Faughnan ME, Su H -
Carnosic Acid Prevents Beta-Amyloid-Induced Injury in Human Neuroblastoma SH-SY5Y Cells via the Induction of Autophagy.
Neurochemical research 2016 Liu J, Su H, Qu QM -
Morphometric characterization of brain arteriovenous malformations for clinical and radiological studies to identify silent intralesional microhemorrhages.
Clinical neuropathology 2016 Pekmezci M, Nelson J, Su H, Hess C, Lawton MT, Sonmez M, Young WL, Kim H, Tihan T -
Bone Fracture Pre-Ischemic Stroke Exacerbates Ischemic Cerebral Injury in Mice.
PloS one 2016 Wang L, Kang S, Zou D, Zhan L, Li Z, Zhu W, Su H -
SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model.
Neurochemical research 2016 Zhang JY, Deng YN, Zhang M, Su H, Qu QM -
Recombinant VLP-Z of JC Polyomavirus: A Novel Vector for Targeting Gene Delivery.
Intervirology 2016 Deng YN, Zeng JY, Su H, Qu QM -
Impact and risk factors of post-stroke bone fracture.
World journal of experimental medicine 2016 Huo K, Hashim SI, Yong KL, Su H, Qu QM -
Abstract 54: Soluble FLT1 Gene Therapy Through Systemic Viral Delivery Reduces the Severity of Mouse Brain Arteriovenous Malformation.
Stroke 2016 Wan Zhu, Fanxia Shen, Shuai Kang, Lei Mao, Zhengda Sun, Dingquan Zou, Rui Zhang, Lei Zhan, John Forsayeth, Hua Su -
Abstract WP111: Activation of a7 Nicotinic Acetylcholine Receptor Improves Blood-Brain Barrier Integrity in Mice with Ischemic Stroke and Bone Fracture.
Stroke 2016 Dingquan Zou, Zhenyi Han, Lei Zhan, Wan Zhu, Shuai Kang, Chen Bao, Alireza Sadighi, Zhao Li, Jeffrey Nelson, Rui Zhang, Hua Su -
12 Genetics and Vascular Biology of Angiogenesis and Vascular Malformations.
Stroke 2016 Helen Kim, Ludmila Pawlikowska, Hua Su, William L. Young -
Vascular Integrity in the Pathogenesis of Brain Arteriovenous Malformation.
Acta neurochirurgica. Supplement 2016 Zhang R, Zhu W, Su H -
Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels✩.
Biotechnology reports (Amsterdam, Netherlands) 2015 Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL -
Review
The role of macrophage in the pathogenesis of brain arteriovenous malformation 2015 Ma L, Guo Y, Zhao YL, Su H -
Inhibition of pathological brain angiogenesis through systemic delivery of AAV vector expressing soluble FLT1.
Gene therapy 2015 Shen F, Mao L, Zhu W, Lawton MT, Pechan P, Colosi P, Wu Z, Scaria A, Su H -
385. Intravenous Delivery of AAV9-CMV-sFLT1 Reduces the Severity of Brain Arteriovenous Malformation Without Causing Significant Side Effects in a Mouse Model.
Molecular Therapy 2015 Wan Zhu, Fanxia Shen, Lei Zhan, Shuai Kang, Rui Zhang, Dingquan Zou, John Forsayeth, Zhijian Wu, Peter Colosi, Hua Su -
Abstract 191: Persistent Infiltration of Active Microglia in Brain Arteriovenous Malformation Causes Unresolved Inflammation and Lesion Progression.
Stroke 2015 Rui Zhang, Vincent Degos, Shuai Kang, Michael Wong, Lei Zhan, Hua Su -
Abstract W P413: Intravenous Delivery of the AAV9-sFLT Vector Reverses the Phenotype of Spontaneously Developed Brain Arteriovenous Malformation in Mice.
Stroke 2015 Lei Mao, Fanxia Shen, Yue He, Lei Zhan, Michael T. Lawton, Hua Su -
Endovascular biopsy: Technical feasibility of novel endothelial cell harvesting devices assessed in a rabbit aneurysm model.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2015 Cooke DL, Bauer D, Sun Z, Stillson C, Nelson J, Barry D, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Su H, Saeed MM -
Endovascular biopsy: Technical feasibility of novel endothelial cell harvesting devices assessed in a rabbit aneurysm model.
Interventional Neuroradiology 2015 Daniel L Cooke, Diana Bauer, Zhengda Sun, Carol Stillson, Jeffrey Nelson, David Barry, Steven W Hetts, Randall T Higashida, Christopher F Dowd, Van V Halbach, Hua Su, Maythem M Saeed -
Recombinant human erythropoietin improves the neurofunctional recovery of rats following traumatic brain injury via an increase in circulating endothelial progenitor cells
Transl Stroke Res.2015 Feb;6(1):50-59. 2015 Wang L, Wang X, Su H, Han Z, Yu H, Wang D, Jiang R, Liu Z, Zhang J. -
Adult mouse venous hypertension model: common carotid artery to external jugular vein anastomosis.
Journal of visualized experiments : JoVE 2015 Yang ST, Rodriguez-Hernandez A, Walker EJ, Young WL, Su H, Lawton MT -
Endovascular Biopsy: Technical Feasibility of Novel Endothelial Cell Harvesting Devices Assessed in a Rabbit Aneurysm Model.
Interventional Neuroradiology 2015 Daniel L. Cooke, Diana Bauer, Zhengda Sun, Carol Stillson, Jeffrey Nelson, David Barry, Steven W. Hetts, Randall T. Higashida, Christopher F. Dowd, Van V. Halbach, Hua Su, Maythem M. Saeed -
Endovascular treatment of severe acute basilar artery occlusion
J Clin Neurosci 2015 Wang L, Shi W, Su Z, Liu X, Su H, Liu J, Liu Z -
Targeted Gene Therapy for Ischemic Stroke.
Gene Delivery and Therapy for Neurological Disorders 2015 Fanxia Shen, Hua Su -
The Role of Macrophage in the Pathogenesis of Brain Arteriovenous Malformation.
International journal of hematology research 2015 Ma L, Guo Y, Zhao YL, Su H -
Endothelial cell high-enrichment from endovascular biopsy sample by laser capture microdissection and fluorescence activated cell sorting.
Journal of biotechnology 2014 Sun Z, Su H, Long B, Sinclair E, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Cooke DL -
Distinctive distribution of lymphocytes in unruptured and previously untreated brain arterviovenous malformation
Neuroimmunology and Neuroinflammation 2014 Guo Y, Tihan T, Lawton MT, Kim H, Young WL, Zhao Y, Su H. -
Endovascular treatment of severe acute basilar artery occlusion.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2014 Wang L, Shi W, Su Z, Liu X, Su H, Liu J, Liu Z, Lawton MT -
Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.
PloS one 2014 Han Z, Shen F, He Y, Degos V, Camus M, Maze M, Young WL, Su H -
Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture.
Journal of neurochemistry 2014 Han Z, Li L, Wang L, Degos V, Maze M, Su H -
Endoglin deficiency impairs stroke recovery.
Stroke 2014 Shen F, Degos V, Chu PL, Han Z, Westbroek EM, Choi EJ, Marchuk D, Kim H, Lawton MT, Maze M, Young WL, Su H -
Brain arteriovenous malformation modeling, pathogenesis, and novel therapeutic targets.
Translational stroke research 2014 Chen W, Choi EJ, McDougall CM, Su H -
Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia.
PloS one 2014 Choi EJ, Chen W, Jun K, Arthur HM, Young WL, Su H -
Abstract W P98: Activation of a7 Nicotinic Acetylcholine Receptor Reduces Pro-Inflammatory Macrophage and Improves Ischemic Stroke Recovery.
Stroke 2014 Zhenying Han, Fanxia Shen, Yue He, Vincent Degos, Marine Camus, Mamta Wankhede, Mervyn Maze, William L. Young, Hua Su -
De novo cerebrovascular malformation in the adult mouse after endothelial Alk1 deletion and angiogenic stimulation.
Stroke 2014 Chen W, Sun Z, Han Z, Jun K, Camus M, Wankhede M, Mao L, Arnold T, Young WL, Su H -
Development of the central nervous system vasculature and the pathogenesis of brain arteriovenous malformations.
Comprehensive Management of Arteriovenous Malformations of the Brain and Spine 2014 Steven W. Hetts, Hua Su, Tarik Tihan, Tomoki Hashimoto, Ludmila Pawlikowska, Michael T. Lawton -
Distinctive distribution of lymphocytes in unruptured and previously untreated brain arteriovenous malformation.
Neuroimmunology and neuroinflammation 2014 Guo Y, Tihan T, Kim H, Hess C, Lawton MT, Young WL, Zhao Y, Su H -
ERRATUM TO: Induction of Brain Arteriovenous Malformation in the Adult Mouse.
Cerebral Angiogenesis 2014 Wanqiu Chen, William L. Young, Hua Su -
Induction of brain arteriovenous malformation in the adult mouse.
Methods in molecular biology (Clifton, N.J.) 2014 Chen W, Young WL, Su H -
Endovascular biopsy: evaluating the feasibility of harvesting endothelial cells using detachable coils.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2013 Cooke DL, Su H, Sun Z, Guo Y, Guo D, Saeed MM, Hetts SW, Higashida RT, Dowd CF, Young WL, Halbach VV -
Bone fracture exacerbates murine ischemic cerebral injury.
Anesthesiology 2013 Degos V, Maze M, Vacas S, Hirsch J, Guo Y, Shen F, Jun K, van Rooijen N, Gressens P, Young WL, Su H -
Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction.
Anesthesiology 2013 Degos V, Vacas S, Han Z, van Rooijen N, Gressens P, Su H, Young WL, Maze M -
Abstract TMP116: AAV-sFLT: A Potential Therapeutic Agent for the Treatment of Brain Angiogenic Diseases.
Stroke 2013 Lei Mao, Fanxia Shen, Wanqiu Chen, Babatunde Akinpelu, Michael T. Lawton, William L. Young, Hua Su -
Abstract TMP118: Alk1 Deficiency Impairs Mural Cell Recruitment During Brain Angiogenesis.
Stroke 2013 Wanqiu Chen, Yi Guo, Kristine Jun, Mamta Wankhede, Hua Su, William L. Young -
Abstract TMP69: Endoglin Deficiency Exacerbates Ischemic Brain Injury.
Stroke 2013 Fanxia Shen, Vincent Degos, Zhenying Han, Eun-Jung Choi, William L. Young, Hua Su -
Endoglin deficiency in bone marrow is sufficient to cause cerebrovascular dysplasia in the adult mouse after vascular endothelial growth factor stimulation.
Stroke 2013 Choi EJ, Walker EJ, Degos V, Jun K, Kuo R, Pile-Spellman J, Su H, Young WL -
Intravenous delivery of adeno-associated viral vector serotype 9 mediates effective gene expression in ischemic stroke lesion and brain angiogenic foci.
Stroke 2012 Shen F, Kuo R, Milon-Camus M, Han Z, Jiang L, Young WL, Su H -
Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.
Arteriosclerosis, thrombosis, and vascular biology 2012 Chen W, Guo Y, Walker EJ, Shen F, Jun K, Oh SP, Degos V, Lawton MT, Tihan T, Davalos D, Akassoglou K, Nelson J, Pile-Spellman J, Su H, Young WL -
Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue.
Neuroreport 2012 Kahle MP, Lee B, Pourmohamad T, Cunningham A, Su H, Kim H, Chen Y, McCulloch CE, Barbaro NM, Lawton MT, Young WL, Bix GJ -
Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation.
Translational stroke research 2012 Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H, Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL -
Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue.
Neuroreport 2012 Michael P. Kahle, Boyeon Lee, Tony Pourmohamad, Austin Cunningham, Hua Su, Helen Kim, Yongmei Chen, Charles E. McCulloch, Nicholas M. Barbaro, Michael T. Lawton, William L. Young, Gregory J. Bix -
Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse.
Cerebrovascular diseases (Basel, Switzerland) 2012 Choi EJ, Walker EJ, Shen F, Oh SP, Arthur HM, Young WL, Su H -
Bevacizumab attenuates VEGF-induced angiogenesis and vascular malformations in the adult mouse brain.
Stroke 2012 Walker EJ, Su H, Shen F, Degos V, Amend G, Jun K, Young WL -
Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture.
Stroke 2012 Guo Y, Saunders T, Su H, Kim H, Akkoc D, Saloner DA, Hetts SW, Hess C, Lawton MT, Bollen AW, Pourmohamad T, McCulloch CE, Tihan T, Young WL, University of California, San Francisco Brain Arteriovenous… -
Abstract 2217: Magnetic Resonance Blood-Brain Barrier Permeability Measurements To Predict Hemorrhagic Transformation In A Rat Model Of Ischemic Stroke.
Stroke 2012 Angelika Hoffmann, Jo¨rg Bredno, Michael F Wendland, Nikita Derugin, Jason Hom, Hua Su, Peter T Ohara, William L Young, Max Wintermark -
Abstract 3153: Endoglin Deficiency in Bone Marrow is Sufficient to Cause Vascular Dysplasia in the Adult Mouse Brain After VEGF Stimulation.
Stroke 2012 Eun-Jung Choi, Espen J. Walker, Kristine Jun, Robert Kuo, Hua Su, William L. Young -
Abstract 3169: Reduced PDGFR-beta Expression After Regional Alk1 Deletion and VEGF Stimulation in the Brain is Associated with Reduced Mural Cell Coverage.
Stroke 2012 Wanqiu Chen, Yi Guo, Andrew W. Bollen, Hua Su, William L. Young -
Abstract 3187: Inflammatory Cell Infiltration Correlates with Hemosiderin Deposition (Intra-lesion Hemorrhage) in Surgical Excised Unruptured Human Brain Arteriovenous Malformations.
Stroke 2012 Yi Guo, Hua Su, Helen Kim, Michael T. Lawton, Andrew W. Bollen, William L. Young -
Abstract 3190: Increased Inflammatory Response in Aged Mice is Associated with More Severe Neuronal Injury at the Acute Stage of Ischemic Stroke.
Stroke 2012 Fanxia Shen, Lidan Jiang, Robert Kuo, Vincent Degos, Espen J. Walker, Hua Su, William L. Young -
Abstract 3194: Bevacizumab (Avastin) Crosses the Blood-brain Barrier and Attenuates VEGF-induced Angiogenesis and Vascular Dysplasia in an Adult Mouse Model of Brain Arteriovenous Malformations.
Stroke 2012 Espen J. Walker, Hua Su, Fanxia Shen, Kristine Jun, Vincent Degos, Gregory Amend, William L. Young -
Sca-1+ cardiosphere-derived cells are enriched for Isl1-expressing cardiac precursors and improve cardiac function after myocardial injury.
PloS one 2012 Ye J, Boyle A, Shih H, Sievers RE, Zhang Y, Prasad M, Su H, Zhou Y, Grossman W, Bernstein HS, Yeghiazarians Y -
Cerebrovascular Casting of the Adult Mouse for 3D Imaging and Morphological Analysis.
Journal of visualized experiments : JoVE 2011 Walker EJ, Shen F, Young WL, Su H -
Cerebrovascular casting of the adult mouse for 3D imaging and morphological analysis.
Journal of visualized experiments : JoVE 2011 Walker EJ, Shen F, Young WL, Su H -
Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke.
Translational stroke research 2011 Jiang L, Shen F, Degos V, Schonemann M, Pleasure SJ, Mellon SH, Young WL, Su H -
Coexpression of angiopoietin-1 with VEGF increases the structural integrity of the blood-brain barrier and reduces atrophy volume.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011 Shen F, Walker EJ, Jiang L, Degos V, Li J, Sun B, Heriyanto F, Young WL, Su H -
Arteriovenous malformation in the adult mouse brain resembling the human disease.
Annals of neurology 2011 Walker EJ, Su H, Shen F, Choi EJ, Oh SP, Chen G, Lawton MT, Kim H, Chen Y, Chen W, Young WL -
Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm.
Acta neurochirurgica. Supplement 2011 Kim H, Su H, Weinsheimer S, Pawlikowska L, Young WL -
Treatment of focal brain ischemia with viral vector-mediated gene transfer.
Methods in molecular biology (Clifton, N.J.) 2011 Su H, Yang GY -
Bone marrow-derived cells contribute to vascular endothelial growth factor-induced angiogenesis in the adult mouse brain by supplying matrix metalloproteinase-9.
Stroke 2010 Hao Q, Su H, Palmer D, Sun B, Gao P, Yang GY, Young WL -
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.
Science (New York, N.Y.) 2010 Kuhnert F, Mancuso MR, Shamloo A, Wang HT, Choksi V, Florek M, Su H, Fruttiger M, Young WL, Heilshorn SC, Kuo CJ -
Evidence of endothelial progenitor cells in the human brain and spinal cord arteriovenous malformations.
Neurosurgery 2010 Gao P, Chen Y, Lawton MT, Barbaro NM, Yang GY, Su H, Ling F, Young WL -
VEGF Induces More Severe Cerebrovascular Dysplasia in Endoglin than in Alk1 Mice.
Translational stroke research 2010 Hao Q, Zhu Y, Su H, Shen F, Yang GY, Kim H, Young WL -
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors.
Cell stem cell 2010 Delaloy C, Liu L, Lee JA, Su H, Shen F, Yang GY, Young WL, Ivey KN, Gao FB -
Endothelial progenitor cell transplantation improves long-term stroke outcome in mice.
Annals of neurology 2010 Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J, Chen Y, Su H, Young WL, Yang GY -
Reduced expression of integrin alphavbeta8 is associated with brain arteriovenous malformation pathogenesis.
The American journal of pathology 2009 Su H, Kim H, Pawlikowska L, Kitamura H, Shen F, Cambier S, Markovics J, Lawton MT, Sidney S, Bollen AW, Kwok PY, Reichardt L, Young WL, Yang GY, Nishimura SL -
Attenuation of brain response to vascular endothelial growth factor-mediated angiogenesis and neurogenesis in aged mice.
Stroke 2009 Gao P, Shen F, Gabriel RA, Law D, Yang EY, Yang E, Yang GY, Young WL, Su H -
Combining angiogenic gene and stem cell therapies for myocardial infarction.
The journal of gene medicine 2009 Pons J, Huang Y, Takagawa J, Arakawa-Hoyt J, Ye J, Grossman W, Kan YW, Su H -
Soluble endoglin modulates aberrant cerebral vascular remodeling.
Annals of neurology 2009 Chen Y, Hao Q, Kim H, Su H, Letarte M, Karumanchi SA, Lawton MT, Barbaro NM, Yang GY, Young WL -
Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain.
Journal of neuropathology and experimental neurology 2009 Zhu Y, Cuevas IC, Gabriel RA, Su H, Nishimura S, Gao P, Fields A, Hao Q, Young WL, Yang GY, Boudreau NJ -
Nonischemic cerebral venous hypertension promotes a pro-angiogenic stage through HIF-1 downstream genes and leukocyte-derived MMP-9.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009 Gao P, Zhu Y, Ling F, Shen F, Lee B, Gabriel RA, Hao Q, Yang GY, Su H, Young WL -
Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development.
Stroke 2008 Kim H, Pawlikowska L, Chen Y, Su H, Yang GY, Young WL -
Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation.
American journal of physiology. Heart and circulatory physiology 2008 Hao Q, Su H, Marchuk DA, Rola R, Wang Y, Liu W, Young WL, Yang GY -
Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2008 Hao Q, Liu J, Pappu R, Su H, Rola R, Gabriel RA, Lee CZ, Young WL, Yang GY -
VEGF improves survival of mesenchymal stem cells in infarcted hearts.
Biochemical and biophysical research communications 2008 Pons J, Huang Y, Arakawa-Hoyt J, Washko D, Takagawa J, Ye J, Grossman W, Su H -
Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model.
Radiology 2008 Saeed M, Martin A, Jacquier A, Bucknor M, Saloner D, Do L, Ursell P, Su H, Kan YW, Higgins CB -
Overexpression of netrin-1 induces neovascularization in the adult mouse brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008 Fan Y, Shen F, Chen Y, Hao Q, Liu W, Su H, Young WL, Yang GY -
Additive effect of AAV-mediated angiopoietin-1 and VEGF expression on the therapy of infarcted heart.
International journal of cardiology 2008 Su H, Takagawa J, Huang Y, Arakawa-Hoyt J, Pons J, Grossman W, Kan YW -
AAV serotype 1 mediates more efficient gene transfer to pig myocardium than AAV serotype 2 and plasmid.
The journal of gene medicine 2008 Su H, Yeghiazarians Y, Lee A, Huang Y, Arakawa-Hoyt J, Ye J, Orcino G, Grossman W, Kan YW -
Development of a cerebral microvascular dysplasia model in rodents.
Acta neurochirurgica. Supplement 2008 Su H, Hao Q, Shen F, Zhu Y, Lee CZ, Young WL, Yang GY -
Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping.
Exercise immunology review 2008 Beiter T, Zimmermann M, Fragasso A, Armeanu S, Lauer UM, Bitzer M, Su H, Young WL, Niess AM, Simon P -
Genetic considerations relevant to intracranial hemorrhage and brain arteriovenous malformations.
Acta neurochirurgica. Supplement 2008 Kim H, Marchuk DA, Pawlikowska L, Chen Y, Su H, Yang GY, Young WL -
Adeno-associated viral vector-mediated hypoxia-regulated VEGF gene transfer promotes angiogenesis following focal cerebral ischemia in mice.
Gene therapy 2007 Shen F, Fan Y, Su H, Zhu Y, Chen Y, Liu W, Young WL, Yang GY -
Neutrophil depletion decreases VEGF-induced focal angiogenesis in the mature mouse brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007 Hao Q, Chen Y, Zhu Y, Fan Y, Palmer D, Su H, Young WL, Yang GY -
Adeno-Associated Viral Vector-Delivered Hypoxia-Inducible Gene Expression in Ischemic Hearts.
Cardiac Gene Expression 2007 Hua Su, Yuet Wai Kan -
Adeno-associated viral vector-delivered hypoxia-inducible gene expression in ischemic hearts.
Methods in molecular biology (Clifton, N.J.) 2007 Su H, Kan YW -
Recombinant adeno-associated viral vector encoding human VEGF165 induces neomicrovessel formation in the adult mouse brain.
Frontiers in bioscience : a journal and virtual library 2006 Shen F, Su H, Liu W, Kan YW, Young WL, Yang GY -
Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice.
Stroke 2006 Shen F, Su H, Fan Y, Chen Y, Zhu Y, Liu W, Young WL, Yang GY -
AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect.
Gene therapy 2006 Su H, Huang Y, Takagawa J, Barcena A, Arakawa-Hoyt J, Ye J, Grossman W, Kan YW -
228. AAV Mediated Hypoxia-Inducible VEGF Expression and Neovascular Formation in Ischemic Pig Myocardium.
Molecular Therapy 2006 Hua Su, Yerem Yeghiazarians, Andrew Lee, Yu Huang, Janice Arakawa-Hoyt, Jianqin Ye, Gina Orcino, William Growssman, Yuet W. Kan -
343. Vascular Endothelial Growth Factor Prevents Bone Marrow Derived-Mesenchymal Stem Cell Senescence In Vitro.
Molecular Therapy 2006 Jennifer Pons, Hua Su, Yu Huang, Y.W. Kan -
Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts.
Proceedings of the National Academy of Sciences of the United States of America 2004 Su H, Joho S, Huang Y, Barcena A, Arakawa-Hoyt J, Grossman W, Kan YW -
Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb.
Molecular therapy : the journal of the American Society of Gene Therapy 2003 Chang DS, Su H, Tang GL, Brevetti LS, Sarkar R, Wang R, Kan YW, Messina LM -
Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model.
Proceedings of the National Academy of Sciences of the United States of America 2002 Su H, Arakawa-Hoyt J, Kan YW -
Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart.
Proceedings of the National Academy of Sciences of the United States of America 2000 Su H, Lu R, Kan YW -
Adeno-associated viral-mediated gene transfer to hepatoma: thymidine kinase/interleukin 2 is more effective in tumor killing in non-ganciclovir (GCV)-treated than in GCV-treated animals.
Molecular therapy : the journal of the American Society of Gene Therapy 2000 Su H, Lu R, Ding R, Kan YW -
Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice.
Proceedings of the National Academy of Sciences of the United States of America 1997 Su H, Lu R, Chang JC, Kan YW -
Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex.
The Journal of cell biology 1996 Kypta RM, Su H, Reichardt LF -
Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene.
Human gene therapy 1996 Su H, Chang JC, Xu SM, Kan YW -
Identification of the transcriptional unit, structural organization, and promoter sequence of the human sex-determining region Y (SRY) gene, using a reverse genetic approach.
American journal of human genetics 1993 Su H, Lau YF -
Demonstration of a stage-specific expression of the ZFY protein in fetal mouse testis using anti-peptide antibodies.
Molecular reproduction and development 1992 Su H, Lau YF -
Isolation of a phylogenetically conserved and testis-specific gene using a monoclonal antibody against the serological H-Y antigen.
Journal of reproductive immunology 1992 Su H, Kozak CA, Veerhuis R, Lau YF, Wiberg U