Howie Rosen, MD
Professor
Neurology
School of Medicine

Education & Training

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• Residency Neurology University of California, San Francisco 1996
• Residency Internal Medicine Albert Einstein College of Medicine 1992
• BA, MD Medicine Boston University 6-year BA/MD program 1989

Videos

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• Frontotemporal Dementia (youtube.com)

Grants and Projects

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• Multidisciplinary Research Fellowship in Alzheimer's disease and Related Dementias, NIH, 2005-2025
• Frontotemporal Dementia: Genes, Images, and Emotions, NIH, 2001-2022
• Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS), NIH, 2014-2019
• New Approaches to Dementia Heterogeneity, NIH, 2004-2019
• Multimodal imaging in frontotemporal degeneration, NIH, 2013-2018
• Awareness of Deficits in Dementia, NIH, 2010-2015
• A Resource for Biomedical Mass Spectrometry, NIH, 1975-2014
• Establishing Therapeutic Efficacy in Frontotemporal Degeneration, NIH, 2013-2014
• The Frontotemporal Lobar Degeneration Neuroimaging Initiative, NIH, 2009-2014
• Emotion in Dementia, NIH, 2002-2006

Publications (341)

Top publication keywords:
Cognitive DysfunctionAphasia, Primary ProgressiveDementiaAmyloid beta-PeptidesFrontotemporal Lobar DegenerationAlzheimer DiseaseBraintau ProteinsPositron-Emission TomographyPick Disease of the BrainAtrophyNeuropsychological TestsNeurodegenerative DiseasesFrontotemporal DementiaSupranuclear Palsy, Progressive

• Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum.
  Brain : a journal of neurology 2024 Illán-Gala I, Lorca-Puls DL, Tee BL, Ezzes Z, de Leon J, Miller ZA, Rubio-Guerra S, Santos-Santos M, Gómez-Andrés D, Grinberg LT, Spina S, Kramer JH, Wauters LD, Henry ML, Boxer AL, Rosen HJ, Miller …
• Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
  JAMA network open 2024 Staffaroni AM, Clark AL, Taylor JC, Heuer HW, Sanderson-Cimino M, Wise AB, Dhanam S, Cobigo Y, Wolf A, Manoochehri M, Forsberg L, Mester C, Rankin KP, Appleby BS, Bayram E, Bozoki A, Clark D, Darby RR…
• Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.
  Neurology 2024 Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto …
• Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
  Cell 2024 Logan T, Simon MJ, Rana A, Cherf GM, Srivastava A, Davis SS, Yoon Low RL, Chiu CL, Fang M, Huang F, Bhalla A, Llapashtica C, Prorok R, Pizzo ME, Calvert MEK, Sun EW, Hsiao-Nakamoto J, Rajendra Y, Lexa…
• Enlarged perivascular spaces are associated with white matter injury, cognition and inflammation in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
  Brain communications 2024 Karvelas N, Oh B, Wang E, Cobigo Y, Tsuei T, Fitzsimons S, Younes K, Ehrenberg A, Geschwind MD, Schwartz D, Kramer JH, Ferguson AR, Miller BL, Silbert LC, Rosen HJ, Elahi FM

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• Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia.
  bioRxiv : the preprint server for biology 2024 Hsiao-Nakamoto J, Chiu CL, VandeVrede L, Ravi R, Vandenberg B, De Groot J, Tsogtbaatar B, Fang M, Auger P, Gould NS, Marchioni F, Powers CA, Davis SS, Suh JH, Alkabsh J, Heuer HW, Lago AL, Scearce-…
• Differential diagnosis of frontotemporal dementia subtypes with explainable deep learning on structural MRI.
  Frontiers in neuroscience 2024 Ma D, Stocks J, Rosen H, Kantarci K, Lockhart SN, Bateman JR, Craft S, Gurcan MN, Popuri K, Beg MF, Wang L, ALLFTD consortium
• Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum.
  Brain : a journal of neurology 2024 Lorca-Puls DL, Gajardo-Vidal A, Mandelli ML, Illán-Gala I, Ezzes Z, Wauters LD, Battistella G, Bogley R, Ratnasiri B, Licata AE, Battista P, García AM, Tee BL, Lukic S, Boxer AL, Rosen HJ, Seeley WW, …
• Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Ho PC, Yu WH, Tee BL, Lee WP, Li C, Gu Y, Yokoyama JS, Reyes-Dumeyer D, Choi YB, Yang HS, Vardarajan BN, Tzuang M, Lieu K, Lu A, Faber KM, Potter ZD, Revta C, Kirsch M, McCallum J, Mei D, Booth B, …
• Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Chen Y, Spina S, Callahan P, Grinberg LT, Seeley WW, Rosen HJ, Kramer JH, Miller BL, Rankin KP
• Neurite-based white matter alterations in MAPT mutation carriers: A multi-shell diffusion MRI study in the ALLFTD consortium.
  Neurobiology of aging 2023 Corriveau-Lecavalier N, Tosakulwong N, Lesnick TG, Fought AJ, Reid RI, Schwarz CG, Senjem ML, Jack CR, Jones DT, Vemuri P, Rademakers R, Ramos EM, Geschwind DH, Knopman DS, Botha H, Savica R, Graff-…
• Functional network collapse in neurodegenerative disease.
  bioRxiv : the preprint server for biology 2023 Brown JA, Lee AJ, Fernhoff K, Pistone T, Pasquini L, Wise AB, Staffaroni AM, Luisa Mandelli M, Lee SE, Boxer AL, Rankin KP, Rabinovici GD, Luisa Gorno Tempini M, Rosen HJ, Kramer JH, Miller BL, Seeley…
• Atrophy in behavioural variant frontotemporal dementia spans multiple large-scale prefrontal and temporal networks.
  Brain : a journal of neurology 2023 Eldaief MC, Brickhouse M, Katsumi Y, Rosen H, Carvalho N, Touroutoglou A, Dickerson BC
• FTLD targets brain regions expressing recently evolved genes.
  medRxiv : the preprint server for health sciences 2023 Pasquini L, Pereira FL, Seddighi S, Zeng Y, Wei Y, Illán-Gala I, Vatsavayai SC, Friedberg A, Lee AJ, Brown JA, Spina S, Grinberg LT, Sirkis DW, Bonham LW, Yokoyama JS, Boxer AL, Kramer JH, Rosen HJ, …
• Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease.
  Brain communications 2023 Llibre-Guerra JJ, Iaccarino L, Coble D, Edwards L, Li Y, McDade E, Strom A, Gordon B, Mundada N, Schindler SE, Tsoy E, Ma Y, Lu R, Fagan AM, Benzinger TLS, Soleimani-Meigooni D, Aschenbrenner AJ, …
• Diminished baseline autonomic outflow in semantic dementia relates to left-lateralized insula atrophy.
  NeuroImage. Clinical 2023 Hua AY, Roy ARK, Kosik EL, Morris NA, Chow TE, Lukic S, Montembeault M, Borghesani V, Younes K, Kramer JH, Seeley WW, Perry DC, Miller ZA, Rosen HJ, Miller BL, Rankin KP, Gorno-Tempini ML, Sturm VE
• Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis.
  Brain : a journal of neurology 2023 Bocancea DI, Svenningsson AL, van Loenhoud AC, Groot C, Barkhof F, Strandberg O, Smith R, Alzheimer’s Disease Neuroimaging Initiative, La Joie R, Rosen HJ, Pontecorvo MJ, Rabinovici GD, van der Flier …
• Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum.
  Annals of neurology 2023 Zhang L, Flagan TM, Häkkinen S, Chu SA, Brown JA, Lee AJ, Pasquini L, Mandelli ML, Gorno-Tempini ML, Sturm VE, Yokoyama JS, Appleby BS, Cobigo Y, Dickerson BC, Domoto-Reilly K, Geschwind DH, Ghoshal N…
• Neuropsychiatric symptoms and imbalance of atrophy in behavioral variant frontotemporal dementia.
  Human brain mapping 2023 Sokolowski A, Roy ARK, Goh SM, Hardy EG, Datta S, Cobigo Y, Brown JA, Spina S, Grinberg L, Kramer J, Rankin KP, Seeley WW, Sturm VE, Rosen HJ, Miller BL, Perry DC
• Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy.
  Genome medicine 2023 Sirkis DW, Warly Solsberg C, Johnson TP, Bonham LW, Sturm VE, Lee SE, Rankin KP, Rosen HJ, Boxer AL, Seeley WW, Miller BL, Geier EG, Yokoyama JS
• Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
  medRxiv : the preprint server for health sciences 2023 Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, …
• Literacy, but not memory, is associated with hippocampal connectivity in illiterate adults.
  Research square 2023 de Paula França Resende E, Lara VP, Santiago ALC, Friedlaender CV, Rosen HJ, Brown JA, Cobigo Y, Silva LLG, de Souza LC, Rincon L, Grinberg LT, Maciel FIP, Caramelli P
• Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2023 Taylor JC, Heuer HW, Clark AL, Wise AB, Manoochehri M, Forsberg L, Mester C, Rao M, Brushaber D, Kramer J, Welch AE, Kornak J, Kremers W, Appleby B, Dickerson BC, Domoto-Reilly K, Fields JA, Ghoshal N…
• Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
  JAMA neurology 2023 Friedberg A, Pasquini L, Diggs R, Glaubitz EA, Lopez L, Illán-Gala I, Iaccarino L, La Joie R, Mundada N, Knudtson M, Neylan K, Brown J, Allen IE, Rankin KP, Bonham LW, Yokoyama JS, Ramos EM, Geschwind…
• Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia.
  Brain communications 2023 Montembeault M, Miller ZA, Geraudie A, Pressman P, Slegers A, Millanski C, Licata A, Ratnasiri B, Mandelli ML, Henry M, Cobigo Y, Rosen HJ, Miller BL, Brambati SM, Gorno-Tempini ML, Battistella G
• Behavioural subphenotypes and their anatomic correlates in neurodegenerative disease.
  Brain communications 2023 Roy ARK, Datta S, Hardy E, Sturm VE, Kramer JH, Seeley WW, Rankin KP, Rosen HJ, Miller BL, Perry DC
• Alzheimer's disease phenotypes show different sleep architecture.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Falgàs N, Walsh CM, Yack L, Simon AJ, Allen IE, Kramer JH, Rosen HJ, Joie R, Rabinovici G, Miller B, Spina S, Seeley WW, Ranasinghe K, Vossel K, Neylan TC, Grinberg LT
• Correction: Cortical microstructure in primary progressive aphasia: a multicenter study.
  Alzheimer's research & therapy 2023 Illán-Gala I, Montal V, Borrego-Écija S, Mandelli ML, Falgàs N, Welch AE, Pegueroles J, Santos-Santos M, Bejanin A, Alcolea D, Dols-Icardo O, Belbin O, Sánchez-Saudinós MB, Bargalló N, González-Ortiz …
• Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Kremers W, Lapid MI, Leger G, …
• Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers.
  JAMA neurology 2023 Casaletto KB, Kornack J, Paolillo EW, Rojas JC, VandeBunte A, Staffaroni AS, Lee S, Heuer H, Forsberg L, Ramos EM, Miller BL, Kramer JH, Yaffe K, Petrucelli L, Boxer A, Boeve B, Gendron TF, Rosen H, …
• Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD 2023 Chow TE, Veziris CR, Mundada N, Martinez-Arroyo AI, Kramer JH, Miller BL, Rosen HJ, Gorno-Tempini ML, Rankin KP, Seeley WW, Rabinovici GD, La Joie R, Sturm VE
• Amyloid, tau and metabolic PET correlates of cognition in early and late-onset Alzheimer's disease.
  Brain : a journal of neurology 2022 Tanner JA, Iaccarino L, Edwards L, Asken BM, Gorno-Tempini ML, Kramer JH, Pham J, Perry DC, Possin K, Malpetti M, Mellinger T, Miller BL, Miller Z, Mundada NS, Rosen HJ, Soleimani-Meigooni DN, Strom A…
• Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Bonham LW, Geier EG, Sirkis DW, Leong JK, Ramos EM, Wang Q, Karydas A, Lee SE, Sturm VE, Sawyer RP, Friedberg A, Ichida JK, Gitler AD, Sugrue L, Cordingley M, Bee W, Weber E, Kramer JH, Rankin KP, …
• Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2022 Younes K, Borghesani V, Montembeault M, Spina S, Mandelli ML, Welch AE, Weis E, Callahan P, Elahi FM, Hua AY, Perry DC, Karydas A, Geschwind D, Huang E, Grinberg LT, Kramer JH, Boxer AL, Rabinovici GD…
• Dynamic autonomic nervous system states arise during emotions and manifest in basal physiology.
  Psychophysiology 2022 Pasquini L, Noohi F, Veziris CR, Kosik EL, Holley SR, Lee A, Brown JA, Roy ARK, Chow TE, Allen I, Rosen HJ, Kramer JH, Miller BL, Saggar M, Seeley WW, Sturm VE
• Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
  Nature medicine 2022 Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, …
• Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling.
  NeuroImage. Clinical 2022 Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, Perrin RJ, Kramer J, Rosen HJ, Alzheimer’s …
• Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia.
  Neurology 2022 Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mackenzie IR…
• Differences in Motor Features of C9orf72, MAPT, or GRN Variant Carriers With Familial Frontotemporal Lobar Degeneration.
  Neurology 2022 Tipton PW, Deutschlaender AB, Savica R, Heckman MG, Brushaber DE, Dickerson BC, Gavrilova RH, Geschwind DH, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Hsiung GR, Huey ED, Irwin DJ, …
• Enhanced positive emotional reactivity in frontotemporal dementia reflects left-lateralized atrophy in the temporal and frontal lobes.
  Cortex; a journal devoted to the study of the nervous system and behavior 2022 Shdo SM, Roy ARK, Datta S, Sible IJ, Lukic S, Perry DC, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW, Holley SR, Gorno-Tempini ML, Sturm VE
• ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion.
  Nature methods 2022 Adebimpe A, Bertolero M, Dolui S, Cieslak M, Murtha K, Baller EB, Boeve B, Boxer A, Butler ER, Cook P, Colcombe S, Covitz S, Davatzikos C, Davila DG, Elliott MA, Flounders MW, Franco AR, Gur RE, Gur …
• Default Mode Network quantitative diffusion and resting-state functional magnetic resonance imaging correlates in sporadic Creutzfeldt-Jakob disease.
  Human brain mapping 2022 Paoletti M, Caverzasi E, Mandelli ML, Brown JA, Henry RG, Miller BL, Rosen HJ, DeArmond SJ, Bastianello S, Seeley WW, Geschwind MD
• Proposed research criteria for prodromal behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2022 Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, …
• Network-wise concordance of multimodal neuroimaging features across the Alzheimer's disease continuum.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2022 Stocks J, Popuri K, Heywood A, Tosun D, Alpert K, Beg MF, Rosen H, Wang L, Alzheimer's Disease Neuroimaging Initiative
• Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders.
  Cell reports. Medicine 2022 Gendron TF, Heckman MG, White LJ, Veire AM, Pedraza O, Burch AR, Bozoki AC, Dickerson BC, Domoto-Reilly K, Foroud T, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Huey ED…
• Cortical hypometabolism reflects local atrophy and tau pathology in symptomatic Alzheimer's disease.
  Brain : a journal of neurology 2022 Strom A, Iaccarino L, Edwards L, Lesman-Segev OH, Soleimani-Meigooni DN, Pham J, Baker SL, Landau SM, Jagust WJ, Miller BL, Rosen HJ, Gorno-Tempini ML, Rabinovici GD, La Joie R, Alzheimer’s Disease …
• Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes.
  Brain communications 2022 Chen KH, Hua AY, Toller G, Lwi SJ, Otero MC, Haase CM, Rankin KP, Rosen HJ, Miller BL, Levenson RW
• Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration.
  JAMA network open 2022 Illán-Gala I, Nigro S, VandeVrede L, Falgàs N, Heuer HW, Painous C, Compta Y, Martí MJ, Montal V, Pagonabarraga J, Kulisevsky J, Lleó A, Fortea J, Logroscino G, Quattrone A, Quattrone A, Perry DC, …
• Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases.
  Brain : a journal of neurology 2022 Benatar M, Wuu J, McHutchison C, Postuma RB, Boeve BF, Petersen R, Ross CA, Rosen H, Arias JJ, Fradette S, McDermott MP, Shefner J, Stanislaw C, Abrahams S, Cosentino S, Andersen PM, Finkel RS, Granit…
• Right uncinate fasciculus supports socioemotional sensitivity in health and neurodegenerative disease.
  NeuroImage. Clinical 2022 Toller G, Mandelli ML, Cobigo Y, Rosen HJ, Kramer JH, Miller BL, Gorno-Tempini ML, Rankin KP
• Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
  JAMA neurology 2022 Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van …
• Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration.
  Neurology 2022 Mattsson-Carlgren N, Grinberg LT, Boxer A, Ossenkoppele R, Jonsson M, Seeley W, Ehrenberg A, Spina S, Janelidze S, Rojas-Martinex J, Rosen H, La Joie R, Lesman-Segev O, Iaccarino L, Kollmorgen G, …
• Cortical microstructure in primary progressive aphasia: a multicenter study.
  Alzheimer's research & therapy 2022 Illán-Gala I, Montal V, Borrego-Écija S, Mandelli ML, Falgàs N, Welch AE, Pegueroles J, Santos-Santos M, Bejanin A, Alcolea D, Dols-Icardo O, Belbin O, Sánchez-Saudinós MB, Bargalló N, González-Ortiz …
• The severity of neuropsychiatric symptoms is higher in early-onset than late-onset Alzheimer's disease.
  European journal of neurology 2021 Falgàs N, Allen IE, Spina S, Grant H, Piña Escudero SD, Merrilees J, Gearhart R, Rosen HJ, Kramer JH, Seeley WW, Neylan TC, Miller BL, Rabinovici GD, Grinberg LT, Walsh CM
• The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Silverman HE, Ake JM, Manoochehri M, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Fields JA, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Lapid MI, Litvan I, …
• Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study.
  The Lancet. Neurology 2021 Thijssen EH, La Joie R, Strom A, Fonseca C, Iaccarino L, Wolf A, Spina S, Allen IE, Cobigo Y, Heuer H, VandeVrede L, Proctor NK, Lago AL, Baker S, Sivasankaran R, Kieloch A, Kinhikar A, Yu L, Valentin…
• Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
  Cell 2021 Logan T, Simon MJ, Rana A, Cherf GM, Srivastava A, Davis SS, Low RLY, Chiu CL, Fang M, Huang F, Bhalla A, Llapashtica C, Prorok R, Pizzo ME, Calvert MEK, Sun EW, Hsiao-Nakamoto J, Rajendra Y, Lexa KW,…
• Clinical, neuroimaging, and neuropathological characterization of a patient with Alzheimer's disease syndrome due to Pick's pathology.
  Neurocase 2021 Toller G, Zitser J, Sukhanov P, Grant H, Miller BL, Kramer JH, Rosen HJ, Rankin KP, Grinberg LT
• Comorbid neuropathological diagnoses in early versus late-onset Alzheimer's disease.
  Brain : a journal of neurology 2021 Spina S, La Joie R, Petersen C, Nolan AL, Cuevas D, Cosme C, Hepker M, Hwang JH, Miller ZA, Huang EJ, Karydas AM, Grant H, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW, …
• Computationally derived anatomic subtypes of behavioral variant frontotemporal dementia show temporal stability and divergent patterns of longitudinal atrophy.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Ranasinghe KG, Toller G, Cobigo Y, Chiang K, Callahan P, Eliazer C, Kramer JH, Rosen HJ, Miller BL, Rankin KP
• Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, Joseph-Mathurin N, Perrin …
• Specific cortical and subcortical grey matter regions are associated with insomnia severity.
  PloS one 2021 Falgàs N, Illán-Gala I, Allen IE, Mumford P, Essanaa YM, Le MM, You M, Grinberg LT, Rosen HJ, Neylan TC, Kramer JH, Walsh CM
• Selective vulnerability to atrophy in sporadic Creutzfeldt-Jakob disease.
  Annals of clinical and translational neurology 2021 Younes K, Rojas JC, Wolf A, Sheng-Yang GM, Paoletti M, Toller G, Caverzasi E, Luisa Mandelli M, Illán-Gala I, Kramer JH, Cobigo Y, Miller BL, Rosen HJ, Geschwind MD
• Multimodal neuroimaging of sex differences in cognitively impaired patients on the Alzheimer's continuum: greater tau-PET retention in females.
  Neurobiology of aging 2021 Edwards L, La Joie R, Iaccarino L, Strom A, Baker SL, Casaletto KB, Cobigo Y, Grant H, Kim M, Kramer JH, Mellinger TJ, Pham J, Possin KL, Rosen HJ, Soleimani-Meigooni DN, Wolf A, Miller BL, Rabinovici…
• APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.
  Hippocampus 2021 Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH
• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
  Neurology 2021 Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, …
• Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2021 Barker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung …
• Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration.
  JAMA network open 2021 Illán-Gala I, Falgàs N, Friedberg A, Castro-Suárez S, Keret O, Rogers N, Oz D, Nigro S, Quattrone A, Quattrone A, Wolf A, Younes K, Santos-Santos M, Borrego-Écija S, Cobigo Y, Dols-Icardo O, Lladó A, …
• Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, …
• Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Illán-Gala I, Casaletto KB, Borrego-Écija S, Arenaza-Urquijo EM, Wolf A, Cobigo Y, Goh SYM, Staffaroni AM, Alcolea D, Fortea J, Blesa R, Clarimon J, Iulita MF, Brugulat-Serrat A, Lladó A, Grinberg LT,…
• Clinical and Neuroimaging Aspects of Familial Frontotemporal Lobar Degeneration Associated with MAPT and GRN Mutations.
  Advances in experimental medicine and biology 2021 Boeve BF, Rosen H
• Smaller Volume in Left-Lateralized Brain Structures Correlates with Greater Experience of Negative Non-target Emotions in Neurodegenerative Diseases.
  Cerebral cortex (New York, N.Y. : 1991) 2021 Chen KH, Hua AY, Lwi SJ, Haase CM, Rosen HJ, Miller BL, Levenson RW
• Spatial Relationships between Molecular Pathology and Neurodegeneration in the Alzheimer's Disease Continuum.
  Cerebral cortex (New York, N.Y. : 1991) 2021 Iaccarino L, La Joie R, Edwards L, Strom A, Schonhaut DR, Ossenkoppele R, Pham J, Mellinger T, Janabi M, Baker SL, Soleimani-Meigooni D, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD
• Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia.
  Annals of neurology 2020 Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, …
• 18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases.
  Brain : a journal of neurology 2020 Soleimani-Meigooni DN, Iaccarino L, La Joie R, Baker S, Bourakova V, Boxer AL, Edwards L, Eser R, Gorno-Tempini ML, Jagust WJ, Janabi M, Kramer JH, Lesman-Segev OH, Mellinger T, Miller BL, Pham J, …
• Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET.
  Neurology 2020 La Joie R, Visani AV, Lesman-Segev OH, Baker SL, Edwards L, Iaccarino L, Soleimani-Meigooni DN, Mellinger T, Janabi M, Miller ZA, Perry DC, Pham J, Strom A, Gorno-Tempini ML, Rosen HJ, Miller BL, …
• Brain volumetric deficits in MAPT mutation carriers: a multisite study.
  Annals of clinical and translational neurology 2020 Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, …
• Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH
• Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease.
  Neurology 2020 Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer JH, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley WW, …
• Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease.
  Alzheimer's research & therapy 2020 Singleton EH, Pijnenburg YAL, Sudre CH, Groot C, Kochova E, Barkhof F, La Joie R, Rosen HJ, Seeley WW, Miller B, Cardoso MJ, Papma J, Scheltens P, Rabinovici GD, Ossenkoppele R
• Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.
  JAMA network open 2020 Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, …
• Salience Network Atrophy Links Neuron Type-Specific Pathobiology to Loss of Empathy in Frontotemporal Dementia.
  Cerebral cortex (New York, N.Y. : 1991) 2020 Pasquini L, Nana AL, Toller G, Brown JA, Deng J, Staffaroni A, Kim EJ, Hwang JL, Li L, Park Y, Gaus SE, Allen I, Sturm VE, Spina S, Grinberg LT, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW
• Baseline neuropsychological profiles in prion disease predict survival time.
  Annals of clinical and translational neurology 2020 Sundaram SE, Staffaroni AM, Walker NC, Casaletto KB, Casey M, Golubjatnikov A, Metcalf S, O'Leary K, Wong K, Benisano K, Forner S, Gonzalez Catalan M, Allen IE, Rosen HJ, Kramer JH, Geschwind MD
• Latent atrophy factors related to phenotypical variants of posterior cortical atrophy.
  Neurology 2020 Groot C, Yeo BTT, Vogel JW, Zhang X, Sun N, Mormino EC, Pijnenburg YAL, Miller BL, Rosen HJ, La Joie R, Barkhof F, Scheltens P, van der Flier WM, Rabinovici GD, Ossenkoppele R
• Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Gentry MT, Lapid MI, Syrjanen J, Calvert K, Hughes S, Brushaber D, Kremers W, Bove J, Brannelly P, Coppola G, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, …
• Comparing two facets of emotion perception across multiple neurodegenerative diseases.
  Social cognitive and affective neuroscience 2020 Brown CL, Hua AY, De Coster L, Sturm VE, Kramer JH, Rosen HJ, Miller BL, Levenson RW
• Longitudinal structural and metabolic changes in frontotemporal dementia.
  Neurology 2020 Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, Rabinovici GD
• Association of Late-Onset Unprovoked Seizures of Unknown Etiology With the Risk of Developing Dementia in Older Veterans.
  JAMA neurology 2020 Keret O, Hoang TD, Xia F, Rosen HJ, Yaffe K
• Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.
  Brain : a journal of neurology 2020 Ducharme S, Dols A, Laforce R, Devenney E, Kumfor F, van den Stock J, Dallaire-Théroux C, Seelaar H, Gossink F, Vijverberg E, Huey E, Vandenbulcke M, Masellis M, Trieu C, Onyike C, Caramelli P, de …
• Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
  Frontiers in neurology 2020 Shdo SM, Ranasinghe KG, Sturm VE, Possin KL, Bettcher BM, Stephens ML, Foley JM, You SC, Rosen HJ, Miller BL, Kramer JH, Rankin KP
• Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials.
  Neurology 2020 Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer H, Hsiung …
• Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer's disease.
  Science advances 2020 Mattsson-Carlgren N, Andersson E, Janelidze S, Ossenkoppele R, Insel P, Strandberg O, Zetterberg H, Rosen HJ, Rabinovici G, Chai X, Blennow K, Dage JL, Stomrud E, Smith R, Palmqvist S, Hansson O
• Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial.
  JAMA neurology 2020 Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R,…
• Language and spatial dysfunction in Alzheimer disease with white matter thorn-shaped astrocytes.
  Neurology 2020 Resende EPF, Nolan AL, Petersen C, Ehrenberg AJ, Spina S, Allen IE, Rosen HJ, Kramer J, Miller BL, Seeley WW, Gorno-Tempini ML, Miller Z, Grinberg LT
• Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH
• Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, …
• Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, …
• New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Boxer AL, Gold M, Feldman H, Boeve BF, Dickinson SL, Fillit H, Ho C, Paul R, Pearlman R, Sutherland M, Verma A, Arneric SP, Alexander BM, Dickerson BC, Dorsey ER, Grossman M, Huey ED, Irizarry MC, …
• The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Boeve B, Bove J, Brannelly P, Brushaber D, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Faber K, Fields J, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-…
• Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel…
• Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, Dickinson S, Domoto-…
• Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET.
  Science translational medicine 2020 La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, …
• Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: Recent findings from ARTFL and LEFFTDS.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Rosen HJ, Boeve BF, Boxer AL
• Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Miyagawa T, Brushaber D, Syrjanen J, Kremers W, Fields J, Forsberg LK, Heuer HW, Knopman D, Kornak J, Boxer A, Rosen HJ, Boeve BF, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever …
• Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes.
  Social cognitive and affective neuroscience 2019 Hua AY, Chen KH, Brown CL, Lwi SJ, Casey JJ, Rosen HJ, Miller BL, Levenson RW
• Nonlinear Z-score modeling for improved detection of cognitive abnormality.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, …
• Grant Report on PREDICT-ADFTD: Multimodal Imaging Prediction of AD/FTD and Differential Diagnosis.
  Journal of psychiatry and brain science 2019 Wang L, Heywood A, Stocks J, Bae J, Ma D, Popuri K, Toga AW, Kantarci K, Younes L, Mackenzie IR, Zhang F, Beg MF, Rosen H, Alzheimer’s Disease Neuroimaging Initiative
• Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
  Brain communications 2019 Miller ZA, Spina S, Pakvasa M, Rosenberg L, Watson C, Mandelli ML, Paredes MF, Joie R, Rabinovici GD, Rosen HJ, Grinberg LT, Huang EJ, Miller BL, Seeley WW, Gorno-Tempini ML
• Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants.
  Acta neuropathologica communications 2019 Lin LC, Nana AL, Hepker M, Hwang JL, Gaus SE, Spina S, Cosme CG, Gan L, Grinberg LT, Geschwind DH, Coppola G, Rosen HJ, Miller BL, Seeley WW
• Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy.
  Neuron 2019 Brown JA, Deng J, Neuhaus J, Sible IJ, Sias AC, Lee SE, Kornak J, Marx GA, Karydas AM, Spina S, Grinberg LT, Coppola G, Geschwind DH, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW
• Evidence of corticofugal tau spreading in patients with frontotemporal dementia.
  Acta neuropathologica 2019 Kim EJ, Hwang JL, Gaus SE, Nana AL, Deng J, Brown JA, Spina S, Lee MJ, Ramos EM, Grinberg LT, Kramer JH, Boxer AL, Gorno-Tempini ML, Rosen HJ, Miller BL, Seeley WW
• Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency.
  Frontiers in neurology 2019 Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL
• Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
  Nature genetics 2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, …
• Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.
  JAMA neurology 2019 Staffaroni AM, Kramer AO, Casey M, Kang H, Rojas JC, Orrú CD, Caughey B, Allen IE, Kramer JH, Rosen HJ, Blennow K, Zetterberg H, Geschwind MD
• Alzheimer Disease-associated Cortical Atrophy Does not Differ Between Chinese and Whites.
  Alzheimer disease and associated disorders 2019 Fan J, Tse M, Carr JS, Miller BL, Kramer JH, Rosen HJ, Bonham LW, Yokoyama JS
• Alzheimer's disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation.
  Acta neuropathologica 2019 Petersen C, Nolan AL, de Paula França Resende E, Miller Z, Ehrenberg AJ, Gorno-Tempini ML, Rosen HJ, Kramer JH, Spina S, Rabinovici GD, Miller BL, Seeley WW, Heinsen H, Grinberg LT
• Factors that predict diagnostic stability in neurodegenerative dementia.
  Journal of neurology 2019 Perry DC, Datta S, Miller ZA, Rankin KP, Gorno-Tempini ML, Kramer JH, Rosen HJ, Seeley WW, Miller BL
• A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.
  Human brain mapping 2019 Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH
• Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain.
  NeuroImage. Clinical 2019 Ossenkoppele R, Iaccarino L, Schonhaut DR, Brown JA, La Joie R, O'Neil JP, Janabi M, Baker SL, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW, Jagust WJ, Rabinovici GD
• Cortical microstructure in the behavioural variant of frontotemporal dementia: looking beyond atrophy.
  Brain : a journal of neurology 2019 Illán-Gala I, Montal V, Borrego-Écija S, Vilaplana E, Pegueroles J, Alcolea D, Sánchez-Saudinós B, Clarimón J, Turón-Sans J, Bargalló N, González-Ortiz S, Rosen HJ, Gorno-Tempini ML, Miller BL, Lladó …
• Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.
  NeuroImage. Clinical 2019 Lee SE, Sias AC, Kosik EL, Flagan TM, Deng J, Chu SA, Brown JA, Vidovszky AA, Ramos EM, Gorno-Tempini ML, Karydas AM, Coppola G, Geschwind DH, Rademakers R, Boeve BF, Boxer AL, Rosen HJ, Miller BL, …
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
  Nature genetics 2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, …
• Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.
  Brain : a journal of neurology 2019 Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller…
• 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes.
  Alzheimer's research & therapy 2019 Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-…
• Evaluating Patient Brain and Behavior Pathways to Caregiver Health in Neurodegenerative Diseases.
  Dementia and geriatric cognitive disorders 2019 Hua AY, Wells JL, Haase CM, Chen KH, Rosen HJ, Miller BL, Levenson RW
• Multimodal imaging in familial FTLD: phenoconversion and planning for the future.
  Brain : a journal of neurology 2019 Boeve BF, Rosen HJ
• Measurement of spinal cord atrophy using phase sensitive inversion recovery (PSIR) imaging in motor neuron disease.
  PloS one 2018 Olney NT, Bischof A, Rosen H, Caverzasi E, Stern WA, Lomen-Hoerth C, Miller BL, Henry RG, Papinutto N
• Primary School Education May Be Sufficient to Moderate a Memory-Hippocampal Relationship.
  Frontiers in aging neuroscience 2018 Resende EPF, Rosen HJ, Chiang K, Staffaroni AM, Allen I, Grinberg LT, Carmona KC, Guimarães HC, Carvalho VA, Barbosa MT, de Souza LC, Caramelli P
• Tau Mutations as a Novel Risk Factor for Cancer-Letter.
  Cancer research 2018 Deutschländer AB, Boeve BF, Rosen HJ, Boxer AL, Wszolek ZK, LEFFTDS Consortium
• Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2018 La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe …
• Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series.
  Journal of neurology 2018 Kim EJ, Brown JA, Deng J, Hwang JL, Spina S, Miller ZA, DeMay MG, Valcour V, Karydas A, Ramos EM, Coppola G, Miller BL, Rosen HJ, Seeley WW, Grinberg LT
• Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.
  Annals of clinical and translational neurology 2018 Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, …
• Resting parasympathetic dysfunction predicts prosocial helping deficits in behavioral variant frontotemporal dementia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2018 Sturm VE, Sible IJ, Datta S, Hua AY, Perry DC, Kramer JH, Miller BL, Seeley WW, Rosen HJ
• Cognition and Incarceration: Cognitive Impairment and Its Associated Outcomes in Older Adults in Jail.
  Journal of the American Geriatrics Society 2018 Ahalt C, Stijacic-Cenzer I, Miller BL, Rosen HJ, Barnes DE, Williams BA
• Network Architecture Underlying Basal Autonomic Outflow: Evidence from Frontotemporal Dementia.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Sturm VE, Brown JA, Hua AY, Lwi SJ, Zhou J, Kurth F, Eickhoff SB, Rosen HJ, Kramer JH, Miller BL, Levenson RW, Seeley WW
• Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA.
  Cortex; a journal devoted to the study of the nervous system and behavior 2018 Mandelli ML, Welch AE, Vilaplana E, Watson C, Battistella G, Brown JA, Possin KL, Hubbard HI, Miller ZA, Henry ML, Marx GA, Santos-Santos MA, Bajorek LP, Fortea J, Boxer A, Rabinovici G, Lee S, Deleon…
• Deficits in physiological and self-conscious emotional response to errors in hoarding disorder.
  Psychiatry research 2018 Zakrzewski JJ, Datta S, Scherling C, Nizar K, Vigil O, Rosen H, Mathews CA
• Analgesic Effect and Potential Cumulative Benefit from Caudal Epidural D5W in Consecutive Participants with Chronic Low-Back and Buttock/Leg Pain.
  Journal of alternative and complementary medicine (New York, N.Y.) 2018 Maniquis-Smigel L, Reeves KD, Rosen HJ, Lyftogt J, Graham-Coleman C, Cheng AL, Rabago D
• Enhanced Positive Emotional Reactivity Undermines Empathy in Behavioral Variant Frontotemporal Dementia.
  Frontiers in neurology 2018 Hua AY, Sible IJ, Perry DC, Rankin KP, Kramer JH, Miller BL, Rosen HJ, Sturm VE
• Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers.
  Annals of clinical and translational neurology 2018 Meeter LHH, Gendron TF, Sias AC, Jiskoot LC, Russo SP, Donker Kaat L, Papma JM, Panman JL, van der Ende EL, Dopper EG, Franzen S, Graff C, Boxer AL, Rosen HJ, Sanchez-Valle R, Galimberti D, Pijnenburg…
• A case of semantic variant primary progressive aphasia with Pick's pathology.
  Neurocase 2018 Caplan A, Marx G, Elofson J, Lis C, Grinberg L, Miller B, Rosen H
• Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
  JAMA neurology 2018 Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, …
• Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration.
  Neurology 2018 Seo SW, Thibodeau MP, Perry DC, Hua A, Sidhu M, Sible I, Vargas JNS, Gaus SE, Rabinovici GD, Rankin KD, Boxer AL, Kramer JH, Rosen HJ, Gorno-Tempini ML, Grinberg LT, Huang EJ, DeArmond SJ, Trojanowski…
• Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
  PLoS medicine 2018 Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J, International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, …
• Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
  PLoS medicine 2018 Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J, International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, …
• Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.
  Neurology 2017 La Joie R, Bejanin A, Fagan AM, Ayakta N, Baker SL, Bourakova V, Boxer AL, Cha J, Karydas A, Jerome G, Maass A, Mensing A, Miller ZA, O'Neil JP, Pham J, Rosen HJ, Tsai R, Visani AV, Miller BL, Jagust …
• Neuroimaging in Dementia.
  Seminars in neurology 2017 Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD
• Clinicopathological correlations in behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2017 Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel…
• Reward deficits in behavioural variant frontotemporal dementia include insensitivity to negative stimuli.
  Brain : a journal of neurology 2017 Perry DC, Datta S, Sturm VE, Wood KA, Zakrzewski J, Seeley WW, Miller BL, Kramer JH, Rosen HJ
• Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimer's disease.
  Brain : a journal of neurology 2017 Bejanin A, Schonhaut DR, La Joie R, Kramer JH, Baker SL, Sosa N, Ayakta N, Cantwell A, Janabi M, Lauriola M, O'Neil JP, Gorno-Tempini ML, Miller ZA, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD
• Progressive Brain Atrophy Despite Persistent Viral Suppression in HIV Patients Older Than 60 Years.
  Journal of acquired immune deficiency syndromes (1999) 2017 Clifford KM, Samboju V, Cobigo Y, Milanini B, Marx GA, Hellmuth JM, Rosen HJ, Kramer JH, Allen IE, Valcour VG
• Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline.
  Neurology 2017 Risacher SL, Anderson WH, Charil A, Castelluccio PF, Shcherbinin S, Saykin AJ, Schwarz AJ, Alzheimer's Disease Neuroimaging Initiative
• In vivo staging of regional amyloid deposition.
  Neurology 2017 Grothe MJ, Barthel H, Sepulcre J, Dyrba M, Sabri O, Teipel SJ, Alzheimer's Disease Neuroimaging Initiative
• Mistakes, Too Few to Mention? Impaired Self-conscious Emotional Processing of Errors in the Behavioral Variant of Frontotemporal Dementia.
  Frontiers in behavioral neuroscience 2017 Scherling CS, Zakrzewski J, Datta S, Levenson RW, Shimamura AP, Sturm VE, Miller BL, Rosen HJ
• Visuospatial Functioning in the Primary Progressive Aphasias.
  Journal of the International Neuropsychological Society : JINS 2017 Watson CL, Possin K, Allen IE, Hubbard HI, Meyer M, Welch AE, Rabinovici GD, Rosen H, Rankin KP, Miller Z, Santos-Santos MA, Kramer JH, Miller BL, Gorno-Tempini ML
• Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease.
  NeuroImage. Clinical 2017 Iaccarino L, Tammewar G, Ayakta N, Baker SL, Bejanin A, Boxer AL, Gorno-Tempini ML, Janabi M, Kramer JH, Lazaris A, Lockhart SN, Miller BL, Miller ZA, O'Neil JP, Ossenkoppele R, Rosen HJ, Schonhaut DR…
• Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
  NeuroImage. Clinical 2017 Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ
• Prosocial deficits in behavioral variant frontotemporal dementia relate to reward network atrophy.
  Brain and behavior 2017 Sturm VE, Perry DC, Wood K, Hua AY, Alcantar O, Datta S, Rankin KP, Rosen HJ, Miller BL, Kramer JH
• Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy.
  NeuroImage. Clinical 2017 Brown JA, Hua AY, Trujllo A, Attygalle S, Binney RJ, Spina S, Lee SE, Kramer JH, Miller BL, Rosen HJ, Boxer AL, Seeley WW
• APOE genotype and early β-amyloid accumulation in older adults without dementia.
  Neurology 2017 Lim YY, Mormino EC, Alzheimer's Disease Neuroimaging Initiative
• Will My Soul Go to Heaven If They Take My Brain? Beliefs and Worries About Brain Donation Among Four Ethnic Groups.
  The Gerontologist 2017 Boise L, Hinton L, Rosen HJ, Ruhl M
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
  Nature genetics 2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers …
• Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.
  Brain imaging and behavior 2017 Yokoyama JS, Marx G, Brown JA, Bonham LW, Wang D, Coppola G, Seeley WW, Rosen HJ, Miller BL, Kramer JH, Dubal DB
• Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups.
  Alzheimer disease and associated disorders 2017 Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC
• Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
  Brain and behavior 2017 Binney RJ, Pankov A, Marx G, He X, McKenna F, Staffaroni AM, Kornak J, Attygalle S, Boxer AL, Schuff N, Gorno-Tempini ML, Weiner MW, Kramer JH, Miller BL, Rosen HJ
• Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
  PLoS medicine 2017 Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen …
• Typical and atypical pathology in primary progressive aphasia variants.
  Annals of neurology 2017 Spinelli EG, Mandelli ML, Miller ZA, Santos-Santos MA, Wilson SM, Agosta F, Grinberg LT, Huang EJ, Trojanowski JQ, Meyer M, Henry ML, Comi G, Rabinovici G, Rosen HJ, Filippi M, Miller BL, Seeley WW, …
• Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
  Frontiers in aging neuroscience 2017 Russo MJ, Campos J, Vázquez S, Sevlever G, Allegri RF, Alzheimer's Disease Neuroimaging Initiative
• Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.
  Acta neuropathologica 2017 Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J, International FTD-Genomics Consortium (IFGC), Momeni P, Sugrue LP, …
• Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2017 Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM…
• Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.
  Neurocase 2017 Bonham LW, Sirkis DW, Fan J, Aparicio RE, Tse M, Ramos EM, Wang Q, Coppola G, Rosen HJ, Miller BL, Yokoyama JS
• Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations.
  Neurology 2017 Spina S, Schonhaut DR, Boeve BF, Seeley WW, Ossenkoppele R, O'Neil JP, Lazaris A, Rosen HJ, Boxer AL, Perry DC, Miller BL, Dickson DW, Parisi JE, Jagust WJ, Murray ME, Rabinovici GD
• Genome-wide association study identifies MAPT locus influencing human plasma tau levels.
  Neurology 2017 Chen J, Yu JT, Wojta K, Wang HF, Zetterberg H, Blennow K, Yokoyama JS, Weiner MW, Kramer JH, Rosen H, Miller BL, Coppola G, Boxer AL, Alzheimer's Disease Neuroimaging Initiative
• White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV.
  Journal of neurovirology 2017 Watson C, Busovaca E, Foley JM, Allen IE, Schwarz CG, Jahanshad N, Nir TM, Esmaeili-Firidouni P, Milanini B, Rosen H, Carmichael OT, Thompson PM, Valcour VG
• Multimodal characterization of older APOE2 carriers reveals selective reduction of amyloid load.
  Neurology 2017 Grothe MJ, Villeneuve S, Dyrba M, Bartrés-Faz D, Wirth M, Alzheimer's Disease Neuroimaging Initiative
• Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers.
  NeuroImage. Clinical 2016 Lee SE, Sias AC, Mandelli ML, Brown JA, Brown AB, Khazenzon AM, Vidovszky AA, Zanto TP, Karydas AM, Pribadi M, Dokuru D, Coppola G, Geschwind DH, Rademakers R, Gorno-Tempini ML, Rosen HJ, Miller BL, …
• ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.
  Journal of acquired immune deficiency syndromes (1999) 2016 Wendelken LA, Jahanshad N, Rosen HJ, Busovaca E, Allen I, Coppola G, Adams C, Rankin KP, Milanini B, Clifford K, Wojta K, Nir TM, Gutman BA, Thompson PM, Valcour V
• Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
  Journal of neurology, neurosurgery, and psychiatry 2016 Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB, International FTD-Genomics Consortium (IFGC),, International Parkinson's Disease Genomics Consortium (…
• Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort.
  NeuroImage. Clinical 2016 Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil JP, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD
• Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.
  Neurology(R) neuroimmunology & neuroinflammation 2016 Miller ZA, Sturm VE, Camsari GB, Karydas A, Yokoyama JS, Grinberg LT, Boxer AL, Rosen HJ, Rankin KP, Gorno-Tempini ML, Coppola G, Geschwind DH, Rademakers R, Seeley WW, Graff-Radford NR, Miller BL
• Progression of brain atrophy in PSP and CBS over 6 months and 1 year.
  Neurology 2016 Dutt S, Binney RJ, Heuer HW, Luong P, Attygalle S, Bhatt P, Marx GA, Elofson J, Tartaglia MC, Litvan I, McGinnis SM, Dickerson BC, Kornak J, Waltzman D, Voltarelli L, Schuff N, Rabinovici GD, Kramer …
• Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer's disease.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Zhang X, Mormino EC, Sun N, Sperling RA, Sabuncu MR, Yeo BT, Alzheimer’s Disease Neuroimaging Initiative
• Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage.
  Neurology 2016 Bertoux M, Sarazin M, Pasquier F, Bottlaender M, de Souza LC, Mioshi E, Hornberger M, Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, …
• Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration.
  JAMA neurology 2016 Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W,…
• Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD.
  Annals of clinical and translational neurology 2016 Tosun D, Schuff N, Rabinovici GD, Ayakta N, Miller BL, Jagust W, Kramer J, Weiner MM, Rosen HJ
• Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.
  Annals of clinical and translational neurology 2016 Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS
• Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia.
  Brain : a journal of neurology 2016 Mandelli ML, Vilaplana E, Brown JA, Hubbard HI, Binney RJ, Attygalle S, Santos-Santos MA, Miller ZA, Pakvasa M, Henry ML, Rosen HJ, Henry RG, Rabinovici GD, Miller BL, Seeley WW, Gorno-Tempini ML
• Polygenic risk of Alzheimer disease is associated with early- and late-life processes.
  Neurology 2016 Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR, Alzheimer's Disease Neuroimaging Initiative
• Decreased Self-Appraisal Accuracy on Cognitive Tests of Executive Functioning Is a Predictor of Decline in Mild Cognitive Impairment.
  Frontiers in aging neuroscience 2016 Scherling CS, Wilkins SE, Zakrezewski J, Kramer JH, Miller BL, Weiner MW, Rosen HJ
• Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study.
  PloS one 2016 Zhang Y, Walter R, Ng P, Luong PN, Dutt S, Heuer H, Rojas-Rodriguez JC, Tsai R, Litvan I, Dickerson BC, Tartaglia MC, Rabinovici G, Miller BL, Rosen HJ, Schuff N, Boxer AL
• Reading words and other people: A comparison of exception word, familiar face and affect processing in the left and right temporal variants of primary progressive aphasia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2016 Binney RJ, Henry ML, Babiak M, Pressman PS, Santos-Santos MA, Narvid J, Mandelli ML, Strain PJ, Miller BL, Rankin KP, Rosen HJ, Gorno-Tempini ML
• Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
  JAMA neurology 2016 Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen…
• Features of Patients With Nonfluent/Agrammatic Primary Progressive Aphasia With Underlying Progressive Supranuclear Palsy Pathology or Corticobasal Degeneration.
  JAMA neurology 2016 Santos-Santos MA, Mandelli ML, Binney RJ, Ogar J, Wilson SM, Henry ML, Hubbard HI, Meese M, Attygalle S, Rosenberg L, Pakvasa M, Trojanowski JQ, Grinberg LT, Rosen H, Boxer AL, Miller BL, Seeley WW, …
• The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum.
  Scientific reports 2016 Xu W, Wang HF, Tan L, Tan MS, Tan CC, Zhu XC, Miao D, Yu WJ, Jiang T, Tan L, Yu JT, Alzheimer’s Disease Neuroimaging Initiative Group
• Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy.
  Parkinsonism & related disorders 2016 Tsai RM, Lobach I, Bang J, Whitwell JL, Senjem ML, Jack CR, Rosen H, Miller B, Boxer AL, AL-108-231 Investigators
• Dominant hemisphere lateralization of cortical parasympathetic control as revealed by frontotemporal dementia.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Guo CC, Sturm VE, Zhou J, Gennatas ED, Trujillo AJ, Hua AY, Crawford R, Stables L, Kramer JH, Rankin K, Levenson RW, Rosen HJ, Miller BL, Seeley WW
• Better verbal memory in women than men in MCI despite similar levels of hippocampal atrophy.
  Neurology 2016 Sundermann EE, Biegon A, Rubin LH, Lipton RB, Mowrey W, Landau S, Maki PM, Alzheimer's Disease Neuroimaging Initiative
• Amyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI.
  Neurology 2016 Landau SM, Horng A, Fero A, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative
• Assessment of the genetic variance of late-onset Alzheimer's disease.
  Neurobiology of aging 2016 Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK, Alzheimer's Disease Genetics Consortium (ADGC)
• Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
  PloS one 2016 Karch CM, Ezerskiy LA, Bertelsen S, Alzheimer’s Disease Genetics Consortium (ADGC), Goate AM
• Alzheimer's Disease Assessment Scale-Cognitive subscale variants in mild cognitive impairment and mild Alzheimer's disease: change over time and the effect of enrichment strategies.
  Alzheimer's research & therapy 2016 Podhorna J, Krahnke T, Shear M, Harrison JE, Alzheimer’s Disease Neuroimaging Initiative
• Plasma neurofilament light chain predicts progression in progressive supranuclear palsy.
  Annals of clinical and translational neurology 2016 Rojas JC, Karydas A, Bang J, Tsai RM, Blennow K, Liman V, Kramer JH, Rosen H, Miller BL, Zetterberg H, Boxer AL
• Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage.
  Neurology 2016 Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, Christine You S, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A,…
• The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume.
  Neurobiology of aging 2016 Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, Westman E, Tsolaki M, …
• Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression.
  JAMA neurology 2016 Zetterberg H, Skillbäck T, Mattsson N, Trojanowski JQ, Portelius E, Shaw LM, Weiner MW, Blennow K, Alzheimer’s Disease Neuroimaging Initiative
• Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
  European journal of nuclear medicine and molecular imaging 2015 Teipel S, Grothe MJ, Alzheimer´s Disease Neuroimaging Initiative
• Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
  JAMA neurology 2015 Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T…
• Highly adaptive tests for group differences in brain functional connectivity.
  NeuroImage. Clinical 2015 Kim J, Pan W, Alzheimer's Disease Neuroimaging Initiative
• Comparison of Visual and Quantitative Florbetapir F 18 Positron Emission Tomography Analysis in Predicting Mild Cognitive Impairment Outcomes.
  JAMA neurology 2015 Schreiber S, Landau SM, Fero A, Schreiber F, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative
• Cortical Amyloid β Deposition and Current Depressive Symptoms in Alzheimer Disease and Mild Cognitive Impairment.
  Journal of geriatric psychiatry and neurology 2015 Chung JK, Plitman E, Nakajima S, Chakravarty MM, Caravaggio F, Gerretsen P, Iwata Y, Graff-Guerrero A, Alzheimer’s Disease Neuroimaging Initiative
• Development of a diagnostic test based on multiple continuous biomarkers with an imperfect reference test.
  Statistics in medicine 2015 García Barrado L, Coart E, Burzykowski T, Alzheimer's Disease Neuroimaging Initiative
• Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults.
  BMC geriatrics 2015 Trzepacz PT, Hochstetler H, Wang S, Walker B, Saykin AJ, Alzheimer’s Disease Neuroimaging Initiative
• Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration.
  NeuroImage. Clinical 2015 Pankov A, Binney RJ, Staffaroni AM, Kornak J, Attygalle S, Schuff N, Weiner MW, Kramer JH, Dickerson BC, Miller BL, Rosen HJ
• Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease.
  Human brain mapping 2015 Ossenkoppele R, Cohn-Sheehy BI, La Joie R, Vogel JW, Möller C, Lehmann M, van Berckel BN, Seeley WW, Pijnenburg YA, Gorno-Tempini ML, Kramer JH, Barkhof F, Rosen HJ, van der Flier WM, Jagust WJ, …
• CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2015 Zhang DF, Li J, Wu H, Cui Y, Bi R, Zhou HJ, Wang HZ, Zhang C, Wang D, Alzheimer's Disease Neuroimaging Initiative (ADNI), Kong QP, Li T, Fang Y, Jiang T, Yao YG
• Cerebral Microbleeds, CSF p-Tau, and Cognitive Decline: Significance of Anatomic Distribution.
  AJNR. American journal of neuroradiology 2015 Chiang GC, Cruz Hernandez JC, Kantarci K, Jack CR, Weiner MW, Alzheimer's Disease Neuroimaging Initiative
• Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects.
  Brain : a journal of neurology 2015 Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, …
• Estimating anatomical trajectories with Bayesian mixed-effects modeling.
  NeuroImage 2015 Ziegler G, Penny WD, Ridgway GR, Ourselin S, Friston KJ, Alzheimer's Disease Neuroimaging Initiative
• The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.
  Brain : a journal of neurology 2015 Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel …
• Associations between Verbal Learning Slope and Neuroimaging Markers across the Cognitive Aging Spectrum.
  Journal of the International Neuropsychological Society : JINS 2015 Gifford KA, Phillips JS, Samuels LR, Lane EM, Bell SP, Liu D, Hohman TJ, Romano RR, Fritzsche LR, Lu Z, Jefferson AL, Alzheimer’s Disease Neuroimaging Initiative
• Longitudinal Partial Volume Correction in 2-[18F]-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Studies of Alzheimer Disease.
  Journal of computer assisted tomography 2015 Malpas CB, Saling MM, Velakoulis D, Desmond P, Hicks RJ, O'Brien TJ, Alzheimer Disease Neuroimaging Initiative
• Frontotemporal Dementia and Psychiatric Illness: Emerging Clinical and Biological Links in Gene Carriers.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2015 Block NR, Sha SJ, Karydas AM, Fong JC, De May MG, Miller BL, Rosen HJ
• Amyloid in dementia associated with familial FTLD: not an innocent bystander.
  Neurocase 2015 Naasan G, Rabinovici GD, Ghosh P, Elofson JD, Miller BL, Coppola G, Karydas A, Fong J, Perry D, Lee SE, Yokoyama JS, Seeley WW, Kramer JH, Weiner MW, Schuff N, Jagust WJ, Grinberg LT, Pribadi M, Yang …
• Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
  JAMA 2015 Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ, Amyloid PET Study Group, Verfaillie SC, Zwan MD, Adriaanse SM, Lammertsma AA, Barkhof F, …
• Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation.
  Brain : a journal of neurology 2015 Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin …
• A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy.
  JAMA neurology 2015 Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, Haase CM, Miller J, Poon WW, Rosen A, Rosen H, …
• Comparing CSF biomarkers and brain MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease.
  Neurology. Clinical practice 2015 Forner SA, Takada LT, Bettcher BM, Lobach IV, Tartaglia MC, Torres-Chae C, Haman A, Thai J, Vitali P, Neuhaus J, Bostrom A, Miller BL, Rosen HJ, Geschwind MD
• Blood protein predictors of brain amyloid for enrichment in clinical trials?
  Alzheimer's & dementia (Amsterdam, Netherlands) 2015 Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wong KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, Covin A, Hehir CT, Baker D, Bazenet C, …
• Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.
  PloS one 2015 Yokoyama JS, Lee AK, Takada LT, Busovaca E, Bonham LW, Chao SZ, Tse M, He J, Schwarz CG, Carmichael OT, Matthews BR, Karydas A, Weiner MW, Coppola G, DeCarli CS, Miller BL, Rosen HJ
• Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
  JAMA neurology 2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, …
• Longitudinal gray matter contraction in three variants of primary progressive aphasia: A tenser-based morphometry study.
  NeuroImage. Clinical 2015 Brambati SM, Amici S, Racine CA, Neuhaus J, Miller Z, Ogar J, Dronkers N, Miller BL, Rosen H, Gorno-Tempini ML
• Applying Automated MR-Based Diagnostic Methods to the Memory Clinic: A Prospective Study.
  Journal of Alzheimer's disease : JAD 2015 Klöppel S, Peter J, Ludl A, Pilatus A, Maier S, Mader I, Heimbach B, Frings L, Egger K, Dukart J, Schroeter ML, Perneczky R, Häussermann P, Vach W, Urbach H, Teipel S, Hüll M, Abdulkadir A, Alzheimer’…
• Common Variants in PLD3 and Correlation to Amyloid-Related Phenotypes in Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD 2015 Wang C, Tan L, Wang HF, Yu WJ, Liu Y, Jiang T, Tan MS, Hao XK, Zhang DQ, Yu JT, Alzheimer's Disease Neuroimaging Initiative
• Identification of Conversion from Normal Elderly Cognition to Alzheimer's Disease using Multimodal Support Vector Machine.
  Journal of Alzheimer's disease : JAD 2015 Zhan Y, Chen K, Wu X, Zhang D, Zhang J, Yao L, Guo X, Alzheimer’s Disease Neuroimaging Initiative
• Mapping the Progression of Atrophy in Early- and Late-Onset Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD 2015 Migliaccio R, Agosta F, Possin KL, Canu E, Filippi M, Rabinovici GD, Rosen HJ, Miller BL, Gorno-Tempini ML
• Risk Stratification Using Cerebrospinal Fluid Biomarkers in Patients with Mild Cognitive Impairment: An Exploratory Analysis.
  Journal of Alzheimer's disease : JAD 2015 Michaud TL, Kane RL, McCarten JR, Gaugler JE, Nyman JA, Kuntz KM, Alzheimer's Disease Neuroimaging Initiative
• Study of amyloid-β peptide functional brain networks in AD, MCI and HC.
  Bio-medical materials and engineering 2015 Jiang J, Duan H, Huang Z, Yu Z, Alzheimer's Disease Neuroimaging Initiative
• Anomalous functional language lateralization in semantic variant PPA.
  Neurology 2014 Miller ZA, Hinkley LB, Herman A, Honma S, Findlay A, Block N, Ketelle R, Rabinovici G, Rosen H, Nagarajan SS, Miller BL, Gorno-Tempini ML
• Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
  JAMA neurology 2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, …
• Damage to left frontal regulatory circuits produces greater positive emotional reactivity in frontotemporal dementia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2014 Sturm VE, Yokoyama JS, Eckart JA, Zakrzewski J, Rosen HJ, Miller BL, Seeley WW, Levenson RW
• Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion.
  Brain : a journal of neurology 2014 Lee SE, Khazenzon AM, Trujillo AJ, Guo CC, Yokoyama JS, Sha SJ, Takada LT, Karydas AM, Block NR, Coppola G, Pribadi M, Geschwind DH, Rademakers R, Fong JC, Weiner MW, Boxer AL, Kramer JH, Rosen HJ, …
• The Chinese Verbal Learning Test specifically assesses hippocampal state.
  American journal of Alzheimer's disease and other dementias 2014 Tsai RM, Leong JK, Dutt S, Chang CC, Lee AK, Chao SZ, Yokoyama JS, Tse M, Kramer JH, Miller BL, Rosen HJ
• Interleukin-6, age, and corpus callosum integrity.
  PloS one 2014 Bettcher BM, Watson CL, Walsh CM, Lobach IV, Neuhaus J, Miller JW, Green R, Patel N, Dutt S, Busovaca E, Rosen HJ, Yaffe K, Miller BL, Kramer JH
• Frontotemporal dementia and its subtypes: a genome-wide association study.
  The Lancet. Neurology 2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernández I, Ruiz A, Boada …
• Self-awareness in neurodegenerative disease relies on neural structures mediating reward-driven attention.
  Brain : a journal of neurology 2014 Shany-Ur T, Lin N, Rosen HJ, Sollberger M, Miller BL, Rankin KP
• Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy.
  Journal of neurology, neurosurgery, and psychiatry 2014 Wagshal D, Sankaranarayanan S, Guss V, Hall T, Berisha F, Lobach I, Karydas A, Voltarelli L, Scherling C, Heuer H, Tartaglia MC, Miller Z, Coppola G, Ahlijanian M, Soares H, Kramer JH, Rabinovici GD, …
• Three-Class Differential Diagnosis among Alzheimer Disease, Frontotemporal Dementia, and Controls.
  Frontiers in neurology 2014 Raamana PR, Rosen H, Miller B, Weiner MW, Wang L, Beg MF
• Anatomical correlates of reward-seeking behaviours in behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2014 Perry DC, Sturm VE, Seeley WW, Miller BL, Kramer JH, Rosen HJ
• An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.
  PLoS genetics 2014 Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind MD, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G
• Is Obesity A Disease or A Behavior Abnormality? Did the AMA Get It Right?
  Missouri medicine 2014 Rosen H
• Metacognition in the behavioral variant of frontotemporal dementia and Alzheimer's disease.
  Neuropsychology 2014 Rosen HJ, Alcantar O, Zakrzewski J, Shimamura AP, Neuhaus J, Miller BL
• Application of quantitative DTI metrics in sporadic CJD.
  NeuroImage. Clinical 2014 Caverzasi E, Henry RG, Vitali P, Lobach IV, Kornak J, Bastianello S, Dearmond SJ, Miller BL, Rosen HJ, Mandelli ML, Geschwind MD
• Neural substrates of socioemotional self-awareness in neurodegenerative disease.
  Brain and behavior 2014 Sollberger M, Rosen HJ, Shany-Ur T, Ullah J, Stanley CM, Laluz V, Weiner MW, Wilson SM, Miller BL, Rankin KP
• Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration.
  Annals of neurology 2014 Scherling CS, Hall T, Berisha F, Klepac K, Karydas A, Coppola G, Kramer JH, Rabinovici G, Ahlijanian M, Miller BL, Seeley W, Grinberg LT, Rosen H, Meredith J, Boxer AL
• Practical utility of amyloid and FDG-PET in an academic dementia center.
  Neurology 2013 Sánchez-Juan P, Ghosh PM, Hagen J, Gesierich B, Henry M, Grinberg LT, O'Neil JP, Janabi M, Huang EJ, Trojanowski JQ, Vinters HV, Gorno-Tempini M, Seeley WW, Boxer AL, Rosen HJ, Kramer JH, Miller BL, …
• NIH EXAMINER: conceptualization and development of an executive function battery.
  Journal of the International Neuropsychological Society : JINS 2013 Kramer JH, Mungas D, Possin KL, Rankin KP, Boxer AL, Rosen HJ, Bostrom A, Sinha L, Berhel A, Widmeyer M
• Depressive symptoms in Chinese-American subjects with cognitive impairment.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013 Chao SZ, Matthews BR, Yokoyama JS, Lai NB, Ong H, Tse M, Yuan RF, Lin A, Kramer J, Yaffe K, Kornak J, Miller BL, Rosen HJ
• MRI markers for mild cognitive impairment: comparisons between white matter integrity and gray matter volume measurements.
  PloS one 2013 Zhang Y, Schuff N, Camacho M, Chao LL, Fletcher TP, Yaffe K, Woolley SC, Madison C, Rosen HJ, Miller BL, Weiner MW
• Progranulin mutations as risk factors for Alzheimer disease.
  JAMA neurology 2013 Perry DC, Lehmann M, Yokoyama JS, Karydas A, Lee JJ, Coppola G, Grinberg LT, Geschwind D, Seeley WW, Miller BL, Rosen H, Rabinovici G
• Financial errors in dementia: testing a neuroeconomic conceptual framework.
  Neurocase 2013 Chiong W, Hsu M, Wudka D, Miller BL, Rosen HJ
• Neuroimaging in frontotemporal dementia.
  International review of psychiatry (Abingdon, England) 2013 Rohrer JD, Rosen HJ
• TDP-43 frontotemporal lobar degeneration and autoimmune disease.
  Journal of neurology, neurosurgery, and psychiatry 2013 Miller ZA, Rankin KP, Graff-Radford NR, Takada LT, Sturm VE, Cleveland CM, Criswell LA, Jaeger PA, Stan T, Heggeli KA, Hsu SC, Karydas A, Khan BK, Grinberg LT, Gorno-Tempini ML, Boxer AL, Rosen HJ, …
• Deficits in self-awareness impact the diagnosis of asymptomatic neurocognitive impairment in HIV.
  AIDS research and human retroviruses 2013 Chiao S, Rosen HJ, Nicolas K, Wendelken LA, Alcantar O, Rankin KP, Miller B, Valcour V
• Patterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia.
  Brain and language 2013 Rohrer JD, Caso F, Mahoney C, Henry M, Rosen HJ, Rabinovici G, Rossor MN, Miller B, Warren JD, Fox NC, Ridgway GR, Gorno-Tempini ML
• Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
  Acta neuropathologica 2013 Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW
• Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease.
  Brain : a journal of neurology 2013 Lehmann M, Ghosh PM, Madison C, Laforce R, Corbetta-Rastelli C, Weiner MW, Greicius MD, Seeley WW, Gorno-Tempini ML, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD
• MRI signatures of brain macrostructural atrophy and microstructural degradation in frontotemporal lobar degeneration subtypes.
  Journal of Alzheimer's disease : JAD 2013 Zhang Y, Tartaglia MC, Schuff N, Chiang GC, Ching C, Rosen HJ, Gorno-Tempini ML, Miller BL, Weiner MW
• Neuroimaging features of C9ORF72 expansion.
  Alzheimer's research & therapy 2012 Yokoyama JS, Rosen HJ
• The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier).
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2012 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M…
• The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementia.
  Journal of the International Neuropsychological Society : JINS 2012 Possin KL, Chester SK, Laluz V, Bostrom A, Rosen HJ, Miller BL, Kramer JH
• Frontotemporal dementia in eight Chinese individuals.
  Neurocase 2012 Chao SZ, Rosen HJ, Azor V, Ong H, Tse MM, Lai NB, Hou CE, Seeley WW, Miller BL, Matthews BR
• Gender modulates the APOE ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, Karydas A, Rosen HJ, Miller BL, Kramer JH, Greicius MD, Alzheimer's Disease Neuroimaging Initiative
• Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion.
  Journal of neurology, neurosurgery, and psychiatry 2012 Khan BK, Yokoyama JS, Takada LT, Sha SJ, Rutherford NJ, Fong JC, Karydas AM, Wu T, Ketelle RS, Baker MC, Hernandez MD, Coppola G, Geschwind DH, Rademakers R, Lee SE, Rosen HJ, Rabinovici GD, Seeley WW…
• Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, …
• Role of right pregenual anterior cingulate cortex in self-conscious emotional reactivity.
  Social cognitive and affective neuroscience 2012 Sturm VE, Sollberger M, Seeley WW, Rankin KP, Ascher EA, Rosen HJ, Miller BL, Levenson RW
• Behaviour, physiology and experience of pathological laughing and crying in amyotrophic lateral sclerosis.
  Brain : a journal of neurology 2011 Olney NT, Goodkind MS, Lomen-Hoerth C, Whalen PK, Williamson CA, Holley DE, Verstaen A, Brown LM, Miller BL, Kornak J, Levenson RW, Rosen HJ
• Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD.
  Neurology 2011 Rabinovici GD, Rosen HJ, Alkalay A, Kornak J, Furst AJ, Agarwal N, Mormino EC, O'Neil JP, Janabi M, Karydas A, Growdon ME, Jang JY, Huang EJ, Dearmond SJ, Trojanowski JQ, Grinberg LT, Gorno-Tempini ML…
• MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia.
  NeuroImage 2011 Tosun D, Rosen H, Miller BL, Weiner MW, Schuff N
• Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.
  Brain : a journal of neurology 2011 Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno…
• Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia.
  International journal of Alzheimer's disease 2011 Zhang Y, Schuff N, Ching C, Tosun D, Zhan W, Nezamzadeh M, Rosen HJ, Kramer JH, Gorno-Tempini ML, Miller BL, Weiner MW
• Anosognosia in neurodegenerative disease.
  Neurocase 2011 Rosen HJ
• Recruitment of Chinese American elders into dementia research: the UCSF ADRC experience.
  The Gerontologist 2011 Chao SZ, Lai NB, Tse MM, Ho RJ, Kong JP, Matthews BR, Miller BL, Rosen HJ
• Know thyself: real-world behavioral correlates of self-appraisal accuracy.
  The Clinical neuropsychologist 2011 Krueger CE, Rosen HJ, Taylor HG, Espy KA, Schatz J, Rey-Casserly C, Kramer JH
• Tracking emotional valence: the role of the orbitofrontal cortex.
  Human brain mapping 2011 Goodkind MS, Sollberger M, Gyurak A, Rosen HJ, Rankin KP, Miller B, Levenson R
• Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia.
  Neuropsychology 2011 Krueger CE, Laluz V, Rosen HJ, Neuhaus JM, Miller BL, Kramer JH
• Neuroimaging in dementia.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2011 Tartaglia MC, Rosen HJ, Miller BL
• Occupation attributes relate to location of atrophy in frontotemporal lobar degeneration.
  Neuropsychologia 2010 Spreng RN, Rosen HJ, Strother S, Chow TW, Diehl-Schmid J, Freedman M, Graff-Radford NR, Hodges JR, Lipton AM, Mendez MF, Morelli SA, Black SE, Miller BL, Levine B
• AVP-923, a combination of dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect and neuropathic pain.
  IDrugs : the investigational drugs journal 2010 Olney N, Rosen H
• Neuroimaging in dementia.
  Continuum (Minneapolis, Minn.) 2010 Tartaglia MC, Vitali P, Migliaccio R, Agosta F, Rosen H
• Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden.
  Brain : a journal of neurology 2010 Rabinovici GD, Furst AJ, Alkalay A, Racine CA, O'Neil JP, Janabi M, Baker SL, Agarwal N, Bonasera SJ, Mormino EC, Weiner MW, Gorno-Tempini ML, Rosen HJ, Miller BL, Jagust WJ
• Longitudinal rates of lobar atrophy in frontotemporal dementia, semantic dementia, and Alzheimer's disease.
  Alzheimer disease and associated disorders 2010 Krueger CE, Dean DL, Rosen HJ, Halabi C, Weiner M, Miller BL, Kramer JH
• Neuroanatomical correlates of cognitive self-appraisal in neurodegenerative disease.
  NeuroImage 2009 Rosen HJ, Alcantar O, Rothlind J, Sturm V, Kramer JH, Weiner M, Miller BL
• The emotional brain: combining insights from patients and basic science.
  Neurocase 2009 Rosen HJ, Levenson RW
• White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI.
  Brain : a journal of neurology 2009 Zhang Y, Schuff N, Du AT, Rosen HJ, Kramer JH, Gorno-Tempini ML, Miller BL, Weiner MW
• Patterns of structural complexity in Alzheimer's disease and frontotemporal dementia.
  Human brain mapping 2009 Young K, Du AT, Kramer J, Rosen H, Miller B, Weiner M, Schuff N
• Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease.
  Journal of the International Neuropsychological Society : JINS 2009 Possin KL, Brambati SM, Rosen HJ, Johnson JK, Pa J, Weiner MW, Miller BL, Kramer JH
• Standardised measurement of self-awareness deficits in FTD and AD.
  Journal of neurology, neurosurgery, and psychiatry 2009 Williamson C, Alcantar O, Rothlind J, Cahn-Weiner D, Miller BL, Rosen HJ
• Correlating DWI MRI with pathologic and other features of Jakob-Creutzfeldt disease.
  Alzheimer disease and associated disorders 2009 Geschwind MD, Potter CA, Sattavat M, Garcia PA, Rosen HJ, Miller BL, DeArmond SJ
• Left frontal lobe contributions to concept formation: a quantitative MRI study of performance on the Delis-Kaplan Executive Function System Sorting Test.
  Journal of clinical and experimental neuropsychology 2008 Fine EM, Delis DC, Dean D, Beckman V, Miller BL, Rosen HJ, Kramer JH
• Neuroimaging in dementia.
  Seminars in neurology 2008 Vitali P, Migliaccio R, Agosta F, Rosen HJ, Geschwind MD
• Dextromethorphan/quinidine sulfate for pseudobulbar affect.
  Drugs of today (Barcelona, Spain : 1998) 2008 Rosen H
• Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease.
  Brain : a journal of neurology 2008 Garbutt S, Matlin A, Hellmuth J, Schenk AK, Johnson JK, Rosen H, Dean D, Kramer J, Neuhaus J, Miller BL, Lisberger SG, Boxer AL
• Cortical neuroanatomy and cognition.
  Handbook of clinical neurology 2008 Rosen HJ, Viskontas IV
• Distinct MRI atrophy patterns in autopsy-proven Alzheimer's disease and frontotemporal lobar degeneration.
  American journal of Alzheimer's disease and other dementias 2007 Rabinovici GD, Seeley WW, Kim EJ, Gorno-Tempini ML, Rascovsky K, Pagliaro TA, Allison SC, Halabi C, Kramer JH, Johnson JK, Weiner MW, Forman MS, Trojanowski JQ, Dearmond SJ, Miller BL, Rosen HJ
• Patterns of white matter atrophy in frontotemporal lobar degeneration.
  Archives of neurology 2007 Chao LL, Schuff N, Clevenger EM, Mueller SG, Rosen HJ, Gorno-Tempini ML, Kramer JH, Miller BL, Weiner MW
• Atrophy progression in semantic dementia with asymmetric temporal involvement: a tensor-based morphometry study.
  Neurobiology of aging 2007 Brambati SM, Rankin KP, Narvid J, Seeley WW, Dean D, Rosen HJ, Miller BL, Ashburner J, Gorno-Tempini ML
• Magnetic resonance imaging correlates of set shifting.
  Journal of the International Neuropsychological Society : JINS 2007 Kramer JH, Quitania L, Dean D, Neuhaus J, Rosen HJ, Halabi C, Weiner MW, Magnotta VA, Delis DC, Miller BL
• 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration.
  Neurology 2007 Rabinovici GD, Furst AJ, O'Neil JP, Racine CA, Mormino EC, Baker SL, Chetty S, Patel P, Pagliaro TA, Klunk WE, Mathis CA, Rosen HJ, Miller BL, Jagust WJ
• Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia.
  Brain : a journal of neurology 2007 Du AT, Schuff N, Kramer JH, Rosen HJ, Gorno-Tempini ML, Rankin K, Miller BL, Weiner MW
• A tensor based morphometry study of longitudinal gray matter contraction in FTD.
  NeuroImage 2007 Brambati SM, Renda NC, Rankin KP, Rosen HJ, Seeley WW, Ashburner J, Weiner MW, Miller BL, Gorno-Tempini ML
• A real reason for patients with pseudobulbar affect to smile.
  Annals of neurology 2007 Rosen HJ, Cummings J
• Behavioral features in semantic dementia vs other forms of progressive aphasias.
  Neurology 2006 Rosen HJ, Allison SC, Ogar JM, Amici S, Rose K, Dronkers N, Miller BL, Gorno-Tempini ML
• Hypoperfusion in frontotemporal dementia and Alzheimer disease by arterial spin labeling MRI.
  Neurology 2006 Du AT, Jahng GH, Hayasaka S, Kramer JH, Rosen HJ, Gorno-Tempini ML, Rankin KP, Miller BL, Weiner MW, Schuff N
• Multiple cognitive deficits in amnestic mild cognitive impairment.
  Dementia and geriatric cognitive disorders 2006 Kramer JH, Nelson A, Johnson JK, Yaffe K, Glenn S, Rosen HJ, Miller BL
• Patterns of frontal lobe atrophy in frontotemporal dementia: a volumetric MRI study.
  Dementia and geriatric cognitive disorders 2006 Perry RJ, Graham A, Williams G, Rosen H, Erzinçlioglu S, Weiner M, Miller B, Hodges J
• Self-conscious emotion deficits in frontotemporal lobar degeneration.
  Brain : a journal of neurology 2006 Sturm VE, Rosen HJ, Allison S, Miller BL, Levenson RW
• Frontotemporal dementia: clinicopathological correlations.
  Annals of neurology 2006 Forman MS, Farmer J, Johnson JK, Clark CM, Arnold SE, Coslett HB, Chatterjee A, Hurtig HI, Karlawish JH, Rosen HJ, Van Deerlin V, Lee VM, Miller BL, Trojanowski JQ, Grossman M
• Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy.
  Archives of neurology 2006 Boxer AL, Geschwind MD, Belfor N, Gorno-Tempini ML, Schauer GF, Miller BL, Weiner MW, Rosen HJ
• Clinical and neuropsychological features of corticobasal degeneration.
  Mechanisms of ageing and development 2005 Belfor N, Amici S, Boxer AL, Kramer JH, Gorno-Tempini ML, Rosen HJ, Miller BL
• Dissociations in hippocampal and frontal contributions to episodic memory performance.
  Neuropsychology 2005 Kramer JH, Rosen HJ, Du AT, Schuff N, Hollnagel C, Weiner MW, Miller BL, Delis DC
• Neuroanatomical correlates of behavioural disorders in dementia.
  Brain : a journal of neurology 2005 Rosen HJ, Allison SC, Schauer GF, Gorno-Tempini ML, Weiner MW, Miller BL
• Neuroanatomical correlates of impaired recognition of emotion in dementia.
  Neuropsychologia 2005 Rosen HJ, Wilson MR, Schauer GF, Allison S, Gorno-Tempini ML, Pace-Savitsky C, Kramer JH, Levenson RW, Weiner M, Miller BL
• Frontotemporal lobar degeneration: demographic characteristics of 353 patients.
  Archives of neurology 2005 Johnson JK, Diehl J, Mendez MF, Neuhaus J, Shapira JS, Forman M, Chute DJ, Roberson ED, Pace-Savitsky C, Neumann M, Chow TW, Rosen HJ, Forstl H, Kurz A, Miller BL
• The natural history of temporal variant frontotemporal dementia.
  Neurology 2005 Seeley WW, Bauer AM, Miller BL, Gorno-Tempini ML, Kramer JH, Weiner M, Rosen HJ
• Regulation of immunity by lysosphingolipids and their G protein-coupled receptors.
  The Journal of clinical investigation 2004 Goetzl EJ, Rosen H
• Neuropsychological and functional measures of severity in Alzheimer disease, frontotemporal dementia, and semantic dementia.
  Alzheimer disease and associated disorders 2004 Rosen HJ, Narvaez JM, Hallam B, Kramer JH, Wyss-Coray C, Gearhart R, Johnson JK, Miller BL
• Cognitive and behavioral profile in a case of right anterior temporal lobe neurodegeneration.
  Cortex; a journal devoted to the study of the nervous system and behavior 2004 Gorno-Tempini ML, Rankin KP, Woolley JD, Rosen HJ, Phengrasamy L, Miller BL
• Hippocampal volume and retention in Alzheimer's disease.
  Journal of the International Neuropsychological Society : JINS 2004 Kramer JH, Schuff N, Reed BR, Mungas D, Du AT, Rosen HJ, Jagust WJ, Miller BL, Weiner MW, Chui HC
• 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions.
  Archives of neurology 2004 Wilhelmsen KC, Forman MS, Rosen HJ, Alving LI, Goldman J, Feiger J, Lee JV, Segall SK, Kramer JH, Lomen-Hoerth C, Rankin KP, Johnson J, Feiler HS, Weiner MW, Lee VM, Trojanowski JQ, Miller BL
• Cognition and anatomy in three variants of primary progressive aphasia.
  Annals of neurology 2004 Gorno-Tempini ML, Dronkers NF, Rankin KP, Ogar JM, Phengrasamy L, Rosen HJ, Johnson JK, Weiner MW, Miller BL
• Recognition of emotion in the frontal and temporal variants of frontotemporal dementia.
  Dementia and geriatric cognitive disorders 2004 Rosen HJ, Pace-Savitsky K, Perry RJ, Kramer JH, Miller BL, Levenson RW
• Right and left medial orbitofrontal volumes show an opposite relationship to agreeableness in FTD.
  Dementia and geriatric cognitive disorders 2004 Rankin KP, Rosen HJ, Kramer JH, Schauer GF, Weiner MW, Schuff N, Miller BL
• Focal right inferotemporal atrophy in AD with disproportionate visual constructive impairment.
  Neurology 2003 Boxer AL, Kramer JH, Du AT, Schuff N, Weiner MW, Miller BL, Rosen HJ
• Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease.
  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 2003 Kramer JH, Jurik J, Sha SJ, Rankin KP, Rosen HJ, Johnson JK, Miller BL
• Cinguloparietal atrophy distinguishes Alzheimer disease from semantic dementia.
  Archives of neurology 2003 Boxer AL, Rankin KP, Miller BL, Schuff N, Weiner M, Gorno-Tempini ML, Rosen HJ
• Emotion comprehension in the temporal variant of frontotemporal dementia.
  Brain : a journal of neurology 2002 Rosen HJ, Perry RJ, Murphy J, Kramer JH, Mychack P, Schuff N, Weiner M, Levenson RW, Miller BL
• Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD.
  Neurology 2002 Rosen HJ, Hartikainen KM, Jagust W, Kramer JH, Reed BR, Cummings JL, Boone K, Ellis W, Miller C, Miller BL
• Patterns of brain atrophy in frontotemporal dementia and semantic dementia.
  Neurology 2002 Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N, Weiner M, Feiwell R, Kramer JH, Miller BL
• Patterns of cerebral atrophy in primary progressive aphasia.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Rosen HJ, Kramer JH, Gorno-Tempini ML, Schuff N, Weiner M, Miller BL
• Neuroanatomy of the self: evidence from patients with frontotemporal dementia.
  Neurology 2001 Miller BL, Seeley WW, Mychack P, Rosen HJ, Mena I, Boone K
• Novel applications of social-personality measures to the study of dementia.
  Neurocase 2001 Mychack P, Rosen H, Miller BL