Horia Todor, PhD
Assistant Researcher
Microbiology and Immunology
School of Medicine

Publications (19)

Top publication keywords:
Bacillus subtilisMembrane ProteinsHalobacterium salinarumClustered Regularly Interspaced Short Palindromic RepeatsSigma FactorTranscription FactorsGenes, BacterialBacteriaMetabolomicsCytoplasmArchaeal ProteinsGenes, EssentialGene Expression Regulation, ArchaealType VI Secretion SystemsTranscription, Genetic

• Correction of a widespread bias in pooled chemical genomics screens improves their interpretability.
  Molecular systems biology 2024 Kim LM, Todor H, Gross CA
• Comprehensive double-mutant analysis of the Bacillus subtilis envelope using double-CRISPRi.
  bioRxiv : the preprint server for biology 2024 Koo BM, Todor H, Sun J, van Gestel J, Hawkins JS, Hearne CC, Banta AB, Huang KC, Peters JM, Gross CA
• Lipopolysaccharide transport regulates bacterial sensitivity to a cell wall-degrading intermicrobial toxin.
  PLoS pathogens 2023 Trotta KL, Hayes BM, Schneider JP, Wang J, Todor H, Rockefeller Grimes P, Zhao Z, Hatleberg WL, Silvis MR, Kim R, Koo BM, Basler M, Chou S
• Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin.
  bioRxiv : the preprint server for biology 2023 Trotta KL, Hayes BM, Schneider JP, Wang J, Todor H, Grimes PR, Zhao Z, Hatleberg WL, Silvis MR, Kim R, Koo BM, Basler M, Chou S
• Three Bacterial DedA Subfamilies with Distinct Functions and Phylogenetic Distribution.
  mBio 2023 Todor H, Herrera N, Gross CA

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• Three bacterial DedA subfamilies with distinct functions and phylogenetic distribution.
  bioRxiv : the preprint server for biology 2023 Todor H, Herrera N, Gross C
• Morphological and Transcriptional Responses to CRISPRi Knockdown of Essential Genes in Escherichia coli.
  mBio 2021 Silvis MR, Rajendram M, Shi H, Osadnik H, Gray AN, Cesar S, Peters JM, Hearne CC, Kumar P, Todor H, Huang KC, Gross CA
• Computational pipeline for designing guide RNAs for mismatch-CRISPRi.
  STAR protocols 2021 van Gestel J, Hawkins JS, Todor H, Gross CA
• Rewiring the specificity of extracytoplasmic function sigma factors.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Todor H, Osadnik H, Campbell EA, Myers KS, Li H, Donohue TJ, Gross CA
• Bacterial CRISPR screens for gene function.
  Current opinion in microbiology 2020 Todor H, Silvis MR, Osadnik H, Gross CA
• Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis.
  Cell systems 2020 Hawkins JS, Silvis MR, Koo BM, Peters JM, Osadnik H, Jost M, Hearne CC, Weissman JS, Todor H, Gross CA
• Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.
  Cell systems 2017 Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA
• Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein.
  mBio 2015 Dulmage KA, Todor H, Schmid AK
• Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences.
  PloS one 2015 Todor H, Gooding J, Ilkayeva OR, Schmid AK
• A transcription factor links growth rate and metabolism in the hypersaline adapted archaeon Halobacterium salinarum.
  Molecular microbiology 2014 Todor H, Dulmage K, Gillum N, Bain JR, Muehlbauer MJ, Schmid AK
• Hsp104 overexpression cures Saccharomyces cerevisiae [PSI+] by causing dissolution of the prion seeds.
  Eukaryotic cell 2014 Park YN, Zhao X, Yim YI, Todor H, Ellerbrock R, Reidy M, Eisenberg E, Masison DC, Greene LE
• Protein-DNA binding dynamics predict transcriptional response to nutrients in archaea.
  Nucleic acids research 2013 Todor H, Sharma K, Pittman AM, Schmid AK
• Sequestration of Sup35 by aggregates of huntingtin fragments causes toxicity of [PSI+] yeast.
  The Journal of biological chemistry 2012 Zhao X, Park YN, Todor H, Moomau C, Masison D, Eisenberg E, Greene LE
• Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation.
  The Journal of biological chemistry 2005 Barrett DM, Black SM, Todor H, Schmidt-Ullrich RK, Dawson KS, Mikkelsen RB